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F

Filippo Beleggia

University of Cologne
H指数:22
被引数:2,077

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A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer

小细胞肺癌中靶向依赖性无义介导降解以维持细胞稳态和免疫控制

Molecular Cancer
IF33.9
2026-08-270
OA
Lucia A. Torres-Fernández; Volker Boehm; Joel Kaufmann; Jonas P. Becker; Maria Garcia-Marquez; Beaunelle de Bruijn; Agnieszka Rumińska; Christian Müller; Graziella Bosco; Nazanin Alavinejad; Laura Lovric; Johanna Bihler; Hanna Schulte; Poorya Davoodi; Anna Schöllhorn; Kian R. Weihrauch; Laura Kaiser; Olta Ibruli; Fanyu Liu; Ariadne Androulidaki; Nina Wobst; Marcel Schmiel; Justinas Valiulis; Lukas Maas; Joshua D’Rozario; Vignesh Sakthivelu; Bianca Göbel; Marian Touet; Johannes Brägelmann; Katja Höpker; Felix John; Jürgen Wolf; Stefan Knapp; Alexander Quaas; Maria Cartolano; Silvia von Karstedt; Filippo Beleggia; Hans-Georg Rammensee; Cécile Gouttefangeas; Hans A. Schlößer; Angelika B. Riemer; Hans Christian Reinhardt; Niels H. Gehring; Martin Peifer; Roman K. Thomas; Julie George
Oncogenic KRAS-driven type I interferon signalling primes pancreatic cancer for necroptosis

KRAS致癌基因驱动的I型干扰素信号为胰腺癌的坏死性凋亡奠定基础

Nature Communications
IF15.7
2026-06-150
OAAI
Sofya Tishina; Alina Dahlhaus; Marta Manik; Lejla Mulalic; Janine Murr; Michael Kotliar; Hassan Rakhsh-Khorshid; Myrto Kostopoulou; Florian Hocher; Jenny Stroh; Julia Beck; Riley M. Williams; Gülce G. Balta; Fanyu Liu; Ali T. Abdallah; Christina M. Bebber; Moritz Reese; Jonathan K. M. Lim; Alexander Quaas; Johannes Brägelmann; Manolis Pasparakis; Filippo Beleggia; Siddharth Balachandran; Anna Trauzold; Gianmaria Liccardi; Igor Astsaturov; Maximilian Reichert; Ariadne Androulidaki; Silvia von Karstedt
Cancer neuroscience: The past, the present, and the road ahead

癌症神经科学：过去、现在与未来之路

Cell
IF42.5
2026-04-160
OAAI
Frank Winkler; Sophie Heuer; Ferdinand Althammer; Hellmut Augustin; Filippo Beleggia; Ihsan Ekin Demir; Julian Koenig; Rohini Kuner; Thomas Kuner; Sonja Loges; Michael Platten; Hans Christian Reinhardt; Judith M. Rich; Felix Sahm; Ruth Martha Stassart; Vera Thiel; Andreas Trumpp; Varun Venkataramani; Wolfgang Wick; Matthia A. Karreman
A disease model resource reveals core principles of tissue-specific cancer evolution

一个疾病模型资源揭示了组织特异性癌症演化的核心原则

Nature
IF48.5
2026-02-250
OAAI
Sebastian Mueller; Niklas de Andrade Krätzig; Markus Tschurtschenthaler; Miguel G. Silva; Chiara Thordsen; Riccardo Trozzo; Perrine Simon; Frederic Saab; Thorsten Kaltenbacher; Magdalena Zukowska; Daniele Lucarelli; Rupert Öllinger; Joscha Griger; Nina Groß; Tanja Groll; Jessica Löprich; Antonio E. Zaurito; Linus R. Schömig; Jeroen M. Bugter; Stefanie Bärthel; Chiara Falcomatà; Alexander Strong; Cordelia Brandt; Mulham Najajreh; Aristeidis Papargyriou; Roman Maresch; Katharina A. N. Collins; David Sailer; Christian Schneeweis; Sebastian Burger; Lisa M. Fröhlich; Christine Klement; Alexander Belka; Juan J. Montero; Ute Jungwirth; Maximilian Reichert; Markus Moser; Jens Neumann; George Vassiliou; Juan Cadiñanos; Ignacio Varela; Carsten Marr; Daniel F. Alonso; Pier-Luigi Lollini; Jean Zhao; Louis Chesler; Clare M. Isacke; Angela Riedel; Christian J. Braun; Martin L. Sos; Filippo Beleggia; Hans C. Reinhardt; Monica Musteanu; Mariano Barbacid; Michael Quante; Marc Schmidt-Supprian; Günter Schneider; Simon Clare; Trevor D. Lawley; Gordon Dougan; Katja Steiger; Nathalie Conte; Allan Bradley; Lena Rad; Dieter Saur; Roland Rad
Lack of caspase 8 directs neuronal progenitor-like reprogramming and small cell lung cancer progression

缺乏caspase 8导致神经祖细胞样重编程和小细胞肺癌进展

Nature Communications
IF15.7
2025-12-180
OAAI
Ariadne Androulidaki; Fanyu Liu; Christina M. Bebber; Ilmars Kisis; Vignesh Sakthivelu; Pascal Hunold; Lioba Koerner; Alina Dahlhaus; Fatma Isil Yapici; Christina Grimm; Alicja Pacholewska; Sofya Tishina; Franka Doskotz; Lucia A. Torres Fernández; Jenny Stroh; Ali T. Abdallah; Julia Beck; Lejla Mulalic; Anna Schmitt; Holger Grüll; Thorsten Persigehl; Alexander Quaas; Martin Peifer; Johannes Brägelmann; H. Christian Reinhardt; Pascal Nieper; Robert Hänsel-Hertsch; Roman K. Thomas; Julie George; Michal R. Schweiger; Manolis Pasparakis; Filippo Beleggia; Silvia von Karstedt
ERBB2 signaling drives immune cell evasion and resistance against immunotherapy in small cell lung cancer

ERBB2信号驱动小细胞肺癌中的免疫细胞逃逸以及对免疫治疗的抵抗

Nature Communications
IF15.7
2025-12-090
OA
Lydia Meder; Charlotte I. Orschel; Cyrielle L. Bouchez; Rahil Gholamipoorfard; Claudia V. Orschel; David Stahl; Christoph Kreer; Mirjam Koker; Marieke Nill; Ilayda G. Kocak; Ka-Won Noh; Xinlei Zhao; Leon Ullrich; Björn Häupl; Josefine Jakob; Marie-Lisa Eich; Alexandra Florin; Holger Grüll; Jürgen Wolf; Filippo Beleggia; Reinhard Büttner; Thomas Oellerich; Florian Klein; Johannes Brägelmann; H. Christian Reinhardt; Nima Abedpour; Roland T. Ullrich
Publisher Correction: Functional synapses between neurons and small cell lung cancer

出版更正：神经元和小细胞肺癌之间的功能性突触

Nature
IF48.5
2025-09-190
OAAI
Vignesh Sakthivelu; Anna Schmitt; Franka Odenthal; Kristiano Ndoci; Marian Touet; Ali H. Shaib; Abdulla Chihab; Gulzar A. Wani; Pascal Nieper; Griffin G. Hartmann; Isabel Pintelon; Ilmars Kisis; Maike Boecker; Naja M. Eckert; Manoela Iannicelli Caiaffa; Olta Ibruli; Julia Weber; Roman Maresch; Christina M. Bebber; Ali Chitsaz; Anna Lütz; Mira Kim Alves Carpinteiro; Kaylee M. Morris; Camilla A. Franchino; Jonas Benz; Laura Pérez-Revuelta; Jorge A. Soriano-Campos; Maxim A. Huetzen; Jonas Goergens; Milica Jevtic; Hannah M. Jahn-Kelleter; Hans Zempel; Aleksandra Placzek; Alexandru A. Hennrich; Karl-Klaus Conzelmann; Hannah L. Tumbrink; Pascal Hunold; Joerg Isensee; Lisa Werr; Felix Gaedke; Astrid Schauss; Marielle Minère; Marie Müller; Henning Fenselau; Yin Liu; Alena Heimsoeth; Gülce S. Gülcüler Balta; Henning Walczak; Christian Frezza; Ron D. Jachimowicz; Julie George; Marcel Schmiel; Johannes Brägelmann; Tim Hucho; Silvia von Karstedt; Martin Peifer; Alessandro Annibaldi; Robert Hänsel-Hertsch; Thorsten Persigehl; Holger Grüll; Martin L. Sos; Guido Reifenberger; Matthias Fischer; Dirk Adriaensen; Reinhard Büttner; Julien Sage; Inge Brouns; Roland Rad; Roman K. Thomas; Max Anstötz; Silvio O. Rizzoli; Matteo Bergami; Elisa Motori; Hans Christian Reinhardt; Filippo Beleggia
Functional synapses between neurons and small cell lung cancer

神经元与小细胞肺癌之间的功能性突触

Nature
IF48.5
2025-09-100
OA
Vignesh Sakthivelu; Anna Schmitt; Franka Odenthal; Kristiano Ndoci; Marian Touet; Ali H. Shaib; Abdulla Chihab; Gulzar A. Wani; Pascal Nieper; Griffin G. Hartmann; Isabel Pintelon; Ilmars Kisis; Maike Boecker; Naja M. Eckert; Manoela Ianicelli Caiaffa; Olta Ibruli; Julia Weber; Roman Maresch; Christina M. Bebber; Ali Chitsaz; Anna Lütz; Mira Kim Alves Carpinteiro; Kaylee M. Morris; Camilla A. Franchino; Jonas Benz; Laura Pérez-Revuelta; Jorge A. Soriano-Campos; Maxim A. Huetzen; Jonas Goergens; Milica Jevtic; Hannah M. Jahn-Kelleter; Hans Zempel; Aleksandra Placzek; Alexandru A. Hennrich; Karl-Klaus Conzelmann; Hannah L. Tumbrink; Pascal Hunold; Joerg Isensee; Lisa Werr; Felix Gaedke; Astrid Schauss; Marielle Minère; Marie Müller; Henning Fenselau; Yin Liu; Alena Heimsoeth; Gülce S. Gülcüler Balta; Henning Walczak; Christian Frezza; Ron D. Jachimowicz; Julie George; Marcel Schmiel; Johannes Brägelmann; Tim Hucho; Silvia von Karstedt; Martin Peifer; Alessandro Annibaldi; Robert Hänsel-Hertsch; Thorsten Persigehl; Holger Grüll; Martin L. Sos; Guido Reifenberger; Matthias Fischer; Dirk Adriaensen; Reinhard Büttner; Julien Sage; Inge Brouns; Roland Rad; Roman K. Thomas; Max Anstötz; Silvio O. Rizzoli; Matteo Bergami; Elisa Motori; Hans Christian Reinhardt; Filippo Beleggia
Imaging mass cytometry dataset of small-cell lung cancer tumors and tumor microenvironments

小细胞肺癌肿瘤及肿瘤微环境的成像质谱 cytometry 数据集

BMC RESEARCH NOTES
IF1.7
2025-09-080
OAAI
Rose, France; Ibruli, Olta; Lichius, Luca; Kiljan, Martha; Gozum, Gokcen; Caiaffa, Manoela Iannicelli; Cai, Jiali; Niu, Li-na; Herter, Jan M.; Grull, Holger; Buttner, Reinhard; Beleggia, Filippo; Bosco, Graziella; George, Julie; Herter-Sprie, Grit S.; Reinhardt, Hans Christian; Bozek, Katarzyna
Inhibition of Nonsense-Mediated Decay in Small Cell Lung Cancer Promotes Tumor Cell Death and T Cell Cytotoxicity

抑制小细胞肺癌中的无义介导降解促进肿瘤细胞死亡和T细胞细胞毒性

Journal of Thoracic Oncology
IF20.8
2025-08-290
PRE
Lucia A. Torres Fernández; Volker Boehm; Joel Kaufmann; Agnieszka Rumińska; Christian Müller; Nazanin Alavinejad; Beaunelle de Bruijn; Laura Lovric; Kian R. Weihrauch; Laura Kaiser; Marcel Schmiel; Lukas Maas; Filippo Beleggia; Graziella Bosco; Ariadne Androulidaki; Liu Fanyu; Silvia von Karstedt; Maria Cartolano; Johannes Brägelmann; Justinas Valiulis; Joshua D’Rozario; Nina Wobst; Katja Höpker; Felix John; Jürgen Wolf; Alexander Quaas; Stefan Knapp; Anna Schöllhorn; Jonas P. Becker; Angelika B. Riemer; Cecile Gouttefangeas; Hans-Georg Rammensee; Niels Gehring; Martin Peifer; Roman K. Thomas; Julie George
Low Caspase 8 Expression Promotes Neuronal Progenitor Mimicry and Small Cell Lung Cancer Metastasis

低Caspase 8表达促进神经元祖细胞拟态和小细胞肺癌转移

Journal of Thoracic Oncology
IF20.8
2025-08-290
PRE
Ariadne Androulidaki; Fanyu Liu; Christina M. Bebber; Ilmars Kisis; Vignesh Sakthivelu; Pascal Hunold; Lioba Koerner; Alina Dahlhaus; Fatma Isil Yapici; Christina Grimm; Alicja Pacholewska; Sofya Tishina; Franka Doskotz; Lucia A. Torres Fernández; Ali T. Abdallah; Julia Beck; Lejla Mulalic; Anna Schmitt; Holger Grüll; Thorsten Persigehl; Alexander Quaas; Johannes Brägelmann; H. Christian Reinhardt; Pascal Nieper; Robert Hänsel-Hertsch; Roman K. Thomas; Julie George; Michal R. Schweiger; Manolis Pasparakis; Filippo Beleggia; Silvia von Karstedt
CDK9 inhibition as an effective therapy for small cell lung cancer
CELL DEATH & DISEASE
IF9.6
2024-05-201
OAAI
Capuccino, L. Valdez; Kleitke, T.; Szokol, B.; Svajda, L.; Martin, F.; Bonechi, F.; Kreko, M.; Azami, S.; Montinaro, A.; Wang, Y.; Nikolov, V.; Kaiser, L.; Bonasera, D.; Saggau, J.; Scholz, T.; Schmitt, A.; Beleggia, F.; Reinhardt, H. C.; George, J.; Liccardi, G.; Walczak, H.; Tovari, J.; Braegelmann, J.; Montero, J.; Sos, M. L.; Orfi, L.; Peltzer, N.
An inducible Cd79b mutation confers ibrutinib sensitivity in mouse models of Myd88-driven diffuse large B-cell lymphoma
BLOOD ADVANCES
IF7.1
2024-02-282
OAAI
Fluemann, Ruth; Hansen, Julia; Meinel, Joern; Pfeiffer, Pauline; Wittkopf, Hannah Goldfarb; Luetz, Anna; Wirtz, Jessica; Moellmann, Michael; Zhou, Tanja; Tabatabai, Areya; Lohmann, Tim; Jauch, Maximilian; Beleggia, Filippo; Pelzer, Benedikt; Ullrich, Fabian; Hoefmann, Svenja; Arora, Aastha; Persigehl, Thorsten; Buettner, Reinhard; von Tresckow, Bastian; Klein, Sebastian; Jachimowicz, Ron D.; Reinhardt, Hans Christian; Knittel, Gero
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
BLOOD CANCER DISCOVERY
IF11.5
2022-11-076
OAAI
Fluemann, Ruth; Hansen, Julia; Pelzer, Benedikt W.; Nieper, Pascal; Lohmann, Tim; Kisis, Ilmars; Riet, Tobias; Kohlhas, Viktoria; Phuong-Hien Nguyen; Peifer, Martin; Abedpour, Nima; Bosco, Graziella; Thomas, Roman K.; Kochanek, Moritz; Knufer, Jacqueline; Jonigkeit, Lorenz; Beleggia, Filippo; Holzem, Alessandra; Buttner, Reinhard; Lohneis, Philipp; Meinel, Jorn; Ortmann, Monika; Persigehl, Thorsten; Hallek, Michael; Calado, Dinis Pedro; Chmielewski, Markus; Klein, Sebastian; Goethert, Joachim R.; Chapuy, Bjoern; Zevnik, Branko; Wunderlich, F. Thomas; von Tresckow, Bastian; Jachimowicz, Ron D.; Melnick, Ari M.; Reinhardt, Hans Christian; Knittel, Gero
Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes

铁死亡反应分离小细胞肺癌 (SCLC) 神经内分泌亚型

NATURE COMMUNICATIONS
IF15.7
2021-04-0691
OAAI
Bebber, Christina M.; Thomas, Emily S.; Stroh, Jenny; Chen, Zhiyi; Androulidaki, Ariadne; Schmitt, Anna; Hoehne, Michaela N.; Stueker, Lukas; Alves, Cleidson de Padua; Khonsari, Armin; Dammert, Marcel A.; Parmaksiz, Fatma; Tumbrink, Hannah L.; Beleggia, Filippo; Sos, Martin L.; Riemer, Jan; George, Julie; Brodesser, Susanne; Thomas, Roman K.; Reinhardt, H. Christian; von Karstedt, Silvia
ATM activity in T cells is critical for immune surveillance of lymphoma in vivo
LEUKEMIA
IF13.4
2019-11-0513
PREAI
Riabinska, Arina; Lehrman, Daria; Jachimowicz, Ron Daniel; Knitter, Gero; Fritz, Christian; Schmitt, Anna; Geyer, Aenne; Heneweer, Carola; Wittersheim, Maike; Frenzel, Lukas P.; Torgovnick, Alessandro; Wiederstein, Janica Lea; Wunderlich, Claudia Maria; Ortmann, Monika; Paillard, Arlette; Woessmann, Wilhelm; Borkhardt, Arndt; Burdach, Stefan; Hansmann, Martin-Leo; Rosenwald, Andreas; Perner, Sven; Mall, Gita; Klapper, Wolfram; Merseburg, Andrea; Krueger, Marcus; Gruell, Holger; Persigehl, Thorsten; Wunderlich, Frank Thomas; Peifer, Martin; Utermoehlen, Olaf; Buettner, Reinhard; Beleggia, Filippo; Reinhardt, Hans Christian
Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta
AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2019-10-0144
OAAI
Moosa, Shahida; Yamamoto, Guilherme L.; Garbes, Lutz; Keupp, Katharina; Beleza-Meireles, Ana; Moreno, Carolina Araujo; Valadares, Eugenia Ribeiro; de Sousa, Sergio B.; Maia, Sofia; Saraiva, Jorge; Honjo, Rachel S.; Kim, Chong Ae; de Menezes, Hamilton Cabral; Lausch, Ekkehart; Lorini, Pablo Villavicencio; Lamounier, Arsonval, Jr.; Bezerra Carniero, Tulio Canella; Giunta, Cecilia; Rohrbach, Marianne; Janner, Marco; Semler, Oliver; Beleggia, Filippo; Li, Yun; Yigit, Goekhan; Reintjes, Nadine; Altmueller, Janine; Nuernberg, Peter; Cavalcanti, Denise P.; Zabel, Bernhard; Warman, Matthew L.; Bertola, Debora R.; Wollnik, Bernd; Netzer, Christian
Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndrome
JOURNAL OF MEDICAL GENETICS
IF3.7
2018-10-1542
PREAI
Paolacci, Stefano; Li, Yun; Agolini, Emanuele; Bellacchio, Emanuele; Arboleda-Bustos, Carlos E.; Carrero, Dido; Bertola, Debora; Al-Gazali, Lihadh; Alders, Mariel; Altmueller, Janine; Arboleda, Gonzalo; Beleggia, Filippo; Bruselles, Alessandro; Ciolfi, Andrea; Gillessen-Kaesbach, Gabriele; Krieg, Thomas; Mohammed, Shehla; Mueller, Christian; Noyelli, Antonio; Ortega, Jenny; Sandoval, Adrian; Velasco, Gloria; Yigit, Goekhan; Arboleda, Humberto; Lopez-Otin, Carlos; Wollnik, Bernd; Tartaglia, Marco; Hennekam, Raoul C.
The Cdkn1aSuPER Mouse as a Tool to Study p53-Mediated Tumor Suppression
CELL REPORTS
IF6.9
2018-10-0123
OAAI
Torgovnick, Alessandro; Heger, Jan Michel; Liaki, Vasiliki; Isensee, Joerg; Schmitt, Anna; Knittel, Gero; Riabinska, Arina; Beleggia, Filippo; Laurien, Lucie; Leeser, Uschi; Juengst, Christian; Siedek, Florian; Vogel, Wenzel; Kluemper, Niklas; Nolte, Hendrik; Wittersheim, Maike; Tharun, Lars; Castiglione, Roberta; Krueger, Marcus; Schauss, Astrid; Perner, Sven; Pasparakis, Manolis; Buettner, Reinhard; Persigehl, Thorsten; Hucho, Tim; Herter-Sprie, Grit Sophie; Schumacher, Bjoern; Reinhardt, Hans Christian

研究方向

暂未获取到该数据
H
Hans Christian Reinhardt
H 指数:49论文数:547被引数:9,468
B
Bernd Wollnik
H 指数:64论文数:295被引数:1.3万
T
Thorsten Persigehl
H 指数:38论文数:390被引数:7,193
A
Anna Schmitt
H 指数:21论文数:150被引数:2,908
R
Reinhard Büttner
H 指数:87论文数:1,013被引数:2.9万
J
Julie George
H 指数:37论文数:173被引数:9,710
S
Silvia von Karstedt
H 指数:23论文数:59被引数:4,269
M
Martin Peifer
H 指数:73论文数:477被引数:3.3万
R
Roman K. Thomas
H 指数:76论文数:488被引数:3.6万
J
Janine Altmüller
H 指数:92论文数:513被引数:3.2万