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J

John T. Heiker

Helmholtz Munich
H指数:27
被引数:2,442

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Halogenated bisphenol A alternatives inhibit aldo-keto reductase 1C1 and induce metabolic alterations in human adipocytes

卤代双酚A替代物抑制醛酮还原酶1C1并诱导人脂肪细胞代谢改变

Journal of Hazardous Materials
IF11.3
2026-08-080
OA
Jasmin Kleißen; Cornelius Goerdeler; Alix Sarah Aldehoff; Isabel Karkossa; Anna Didio; Johannes Schmidt; Stefan Kalkhof; Jörg Lehmann; Ulrike Rolle-Kampczyk; Marina Grimaldi; Patrick Balaguer; Maximilian Faissner; Christoph Flamm; Martin Wabitsch; John Thomas Heiker; Kristin Schubert; Martin von Bergen
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

脂肪细胞肌红蛋白是能量消耗的决定因素，也是限制肥胖的潜在靶点

Advanced Science
IF14.1
2026-06-250
OAAI
Christian Strehlau; Helen Broghammer; Claudia Gebhardt; Anne Hoffmann; Tobias Hagemann; Şeyma Midilli; Rachel S. Zimmer; Kristin Schubert; Vasiliki Karagiannakou; Anastasia Georgiadi; Mario Ost; Martin Krüger; Lisa Roth; Kerstin Krause; Nora Klöting; Maria Keller; Martin Wabitsch; Rima Nuwayhid; Roland H. Stimson; Michael Stumvoll; Matthias Blüher; Juliane Weiner; John T. Heiker
Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo

血管胰高血糖素样肽-1抑制剂（vaspin）对脂肪细胞脂解作用的抑制损害了体内的体温调节功能。

Nature Communications
IF15.7
2025-12-100
OAAI
Inka Rapöhn; Helen Broghammer; Anne Hoffmann; Kevin Möhlis; Anna Moormann; Isabell Kaczmarek; Doreen Thor; Henning Großkopf; Laura Krieg; Isabel Karkossa; Kristin Schubert; Martin von Bergen; Kerstin Krause; Jana Breitfeld; Peter Kovacs; Nora Klöting; Rima Nuwayhid; Stefan Langer; Adhideb Ghosh; Christian Wolfrum; Michael Stumvoll; Matthias Blüher; John T. Heiker; Juliane Weiner
13C metabolic tracing in human SGBS cells provides a potential new approach methodology for assessing metabolism-disrupting properties of environmental chemicals

13C代谢示踪在人类SGBS细胞中的应用为评估环境化学物的代谢干扰特性提供了一种潜在的新方法。

Journal of Hazardous Materials
IF11.3
2025-11-040
OAAI
Cornelius Goerdeler; Beatrice Engelmann; Helen Broghammer; Alix Sarah Aldehoff; Martin Wabitsch; Kristin Schubert; Matthias Blüher; John T. Heiker; Ulrike Rolle-Kampczyk; Martin von Bergen
Advanced Proteomics Approaches Hold Potential for the Risk Assessment of Metabolism-Disrupting Chemicals as Omics-Based NAM: A Case Study Using the Phthalate Substitute DINCH

先进蛋白质组学方法作为基于组学的NAM，在代谢干扰化学物质的风险评估方面具有潜力：以邻苯二甲酸酯替代品DINCH为例研究

Environmental Science & Technology
IF11.3
2025-07-300
OA
Alix Sarah Aldehoff; Isabel Karkossa; Helen Broghammer; Sontje Krupka; Juliane Weiner; Cornelius Goerdeler; Rima Nuwayhid; Stefan Langer; Martin Wabitsch; Ulrike Rolle-Kampczyk; Nora Klöting; Matthias Blüher; John T. Heiker; Martin von Bergen; Kristin Schubert
Metabolomics in human SGBS cells as new approach method for studying adipogenic effects: Analysis of the effects of DINCH and MINCH on central carbon metabolism

人SGBS细胞中的代谢组学作为研究脂肪形成作用的新方法: DINCH和MINCH对中心碳代谢的影响分析

ENVIRONMENTAL RESEARCH
IF7.7
2024-07-010
OAAI
Goerdeler, Cornelius; Engelmann, Beatrice; Aldehoff, Alix Sarah; Schaffert, Alexandra; Blueher, Matthias; Heiker, John T.; Wabitsch, Martin; Schubert, Kristin; Rolle-Kampczyk, Ulrike; von Bergen, Martin
Genetic dissection of serum vaspin highlights its causal role in lipid metabolism
OBESITY
IF4.7
2023-09-262
OAAI
Breitfeld, Jana; Horn, Katrin; Le Duc, Diana; Velluva, Akhil; Marzi, Carola; Grallert, Harald; Friedrich, Nele; Pietzner, Maik; Voelker, Uwe; Voelzke, Henry; Ahlqvist, Emma; Aly, Dina Mansour; Tuomi, Tiinamaija; Baber, Ronny; Kratzsch, Juergen; Thiery, Joachim; Isermann, Berend; Loeffler, Markus; Kloeting, Nora; Blueher, Matthias; Stumvoll, Michael; Heiker, John T.; Toenjes, Anke; Scholz, Markus; Kovacs, Peter
Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans
CLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
2022-12-088
OAAI
Christen, Lisa; Broghammer, Helen; Rapoehn, Inka; Moehlis, Kevin; Strehlau, Christian; Ribas-Latre, Aleix; Gebhardt, Claudia; Roth, Lisa; Krause, Kerstin; Landgraf, Kathrin; Koerner, Antje; Rohde-Zimmermann, Kerstin; Hoffmann, Anne; Kloeting, Nora; Ghosh, Adhideb; Sun, Wenfei; Dong, Hua; Wolfrum, Christian; Rassaf, Tienush; Hendgen-Cotta, Ulrike B.; Stumvoll, Michael; Blueher, Matthias; Heiker, John T.; Weiner, Juliane
Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity

在饮食诱导的肥胖中，胃旁路微生物群的功能变化通过肠FXR-TGR5串扰重新激活产热脂肪组织和系统葡萄糖控制

MICROBIOME
IF12.7
2022-06-2440
OAAI
Muenzker, Julia; Haase, Nadine; Till, Andreas; Sucher, Robert; Haange, Sven-Bastiaan; Nemetschke, Linda; Gnad, Thorsten; Jaeger, Elisabeth; Chen, Jiesi; Riede, Sjaak J.; Chakaroun, Rima; Massier, Lucas; Kovacs, Peter; Ost, Mario; Rolle-Kampczyk, Ulrike; Jehmlich, Nico; Weiner, Juliane; Heiker, John T.; Kloeting, Nora; Seeger, Gudrun; Morawski, Markus; Keitel, Verena; Pfeifer, Alexander; von Bergen, Martin; Heeren, Joerg; Kruegel, Ute; Fenske, Wiebke K.
Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes

邻苯二甲酸二 (2-乙基己基) 酯替代物通过激活ppar γ 加速人体脂肪生成，并在成熟脂肪细胞中引起氧化应激和代谢稳态受损

ENVIRONMENT INTERNATIONAL
IF9.7
2022-06-0141
OAAI
Schaffert, Alexandra; Karkossa, Isabel; Ueberham, Elke; Schlichting, Rita; Walter, Katharina; Arnold, Josi; Blueher, Matthias; Heiker, John T.; Lehmann, Joerg; Wabitsch, Martin; Escher, Beate I.; von Bergen, Martin; Schubert, Kristin
Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse
COMMUNICATIONS BIOLOGY
IF5.1
2022-05-032
OAAI
Muller-Eigner, Annika; Sanz-Moreno, Adrian; de-Diego, Irene; Venkatasubramani, Anuroop Venkateswaran; Langhammer, Martina; Gerlini, Raffaele; Rathkolb, Birgit; Aguilar-Pimentel, Antonio; Klein-Rodewald, Tanja; Calzada-Wack, Julia; Becker, Lore; Palma-Vera, Sergio; Gille, Benedikt; Forne, Ignasi; Imhof, Axel; Meng, Chen; Ludwig, Christina; Koch, Franziska; Heiker, John T.; Kuhla, Angela; Caton, Vanessa; Brenmoehl, Julia; Reyer, Henry; Schoen, Jennifer; Fuchs, Helmut; Gailus-Durner, Valerie; Hoeflich, Andreas; de Angelis, Martin Hrabe; Peleg, Shahaf

研究方向

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M
Matthias Blüher
H 指数:122论文数:1,234被引数:8.0万
M
Michael Stümvoll
H 指数:137论文数:1,085被引数:9.2万
N
Nora Klöting
H 指数:61论文数:319被引数:1.5万
J
Juliane Weiner
H 指数:15论文数:43被引数:982
P
Péter Kovács
H 指数:97论文数:1,026被引数:6.6万
K
Kerstin Krause
H 指数:27论文数:114被引数:2,146
A
Annette G. Beck‐Sickinger
H 指数:76论文数:683被引数:2.0万
M
Martin von Bergen�
H 指数:83论文数:592被引数:3.1万
K
Kristin Schubert
H 指数:29论文数:122被引数:2,787
A
Anke Tönjes
H 指数:83论文数:545被引数:5.1万