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Y

Yang Lee

MRC Laboratory of Molecular Biology
H指数:22
被引数:2,379

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Novel WRN helicase inhibitors selectively target microsatellite unstable cancer cells
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Picco, Gabriele; Rao, Yanhua; Al Saedi, Angham; Vieira, Sara F.; Lee, Yang; Shenje, Ray; Bhosle, Shriram; Walker, Samantha; May, Kieron; Herranz-Ors, Carmen; Dicer, Cansu; Gibson, Freddy; Banerjee, Ruby; Werner, Thilo; Cottom, Josh; Peng, Yang; Deng, Nanhua; Landis, Phil; Angel, Thomas; Bush, Jacob; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Lightfoot, Howard; Zappacosta, Francesca; Pettinger, Jonathan; Barthorpe, Syd; Eberl, Chris; Jones, Brian; Schneck, Jess; Murphy, Dennis; Taygerly, Josh; DeMartino, Mike; Coelho, Matthew; Houseley, Jon; Schwartz, Benjamin; Garnett, Mathew J.
Structure determination by cryoEM at 100 keV

100 keV低温下的结构测定

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-11-2711
OAAI
McMullan, Greg; Naydenova, Katerina; Mihaylov, Daniel; Yamashita, Keitaro; Peet, Mathew J.; Wilson, Hugh; Dickerson, Joshua L.; Chen, Shaoxia; Cannone, Giuseppe; Lee, Yang; Hutchings, Katherine A.; Gittins, Olivia; Sobhy, Mohamed A.; Wells, Torquil; El-Gomati, Mohamed M.; Dalby, Jason; Meffert, Matthias; Schulze-Briese, Clemens; Henderson, Richard; Russo, Christopher J.
A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine- induced ROCK2/JAM-A complex

淋巴管的3D仿生模型通过细胞因子诱导的ROCK2/jam-a复合物揭示细胞-细胞连接收紧和淋巴水肿

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-10-025
OAAI
Lee, Esak; Chan, Siu-Lung; Lee, Yang; Polacheck, William J.; Kwak, Sukyoung; Wen, Aiyun; Nguyen, Duc- Huy T.; Kutys, Matthew L.; Alimperti, Stella; Kolarzyk, Anna M.; Kwak, Tae Joon; Eyckmans, Jeroen; Bielenberg, Diane R.; Chen, Hong; Chen, Christopher S.
A small-molecule inhibitor of WRN selectively kills MSI-H cancer cells and phenocopies WRN genetic defects
CANCER RESEARCH
IF16.6
2023-04-041
PRE
Rao, Yanhua; Srivatsan, Anjana; Liimatta, Marya; Munoz, Diana; Quirit, Jeanne; Shi, Jianxia; Nguyen, An; Xin Linghu; Federowicz, Federowicz; Jones, Brian; Fleury, Melissa; Newby, Zach; Dillon, Michael P.; Barsanti, Paul A.; Lackner, Mark R.; White, Michael A.; Lee, Yang; Landis, Phil; Peng, Yang; Cicchini, Michelle; Cottom, Josh; Nickels, Leng; Brnardic, Ed; DeMartino, Michael; Taygerly, Josh
Epsin-mediated degradation of IP3R1 fuels atherosclerosis
NATURE COMMUNICATIONS
IF15.7
2020-08-0723
OAAI
Dong, Yunzhou; Lee, Yang; Cui, Kui; He, Ming; Wang, Beibei; Bhattacharjee, Sudarshan; Zhu, Bo; Yago, Tadayuki; Zhang, Kun; Deng, Lin; Ouyang, Kunfu; Wen, Aiyun; Cowan, Douglas B.; Song, Kai; Yu, Lili; Brophy, Megan L.; Liu, Xiaolei; Wylie-Sears, Jill; Wu, Hao; Wong, Scott; Cui, Guanglin; Kawashima, Yusuke; Matsumoto, Hiroyuki; Kodera, Yoshio; Wojcikiewicz, Richard J. H.; Srivastava, Sanjay; Bischoff, Joyce; Wang, Da-Zhi; Ley, Klaus; Chen, Hong

研究方向

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P
Paul G. Crichton
H 指数:24论文数:53被引数:2,229
E
Edmund R.S. Kunji
H 指数:62论文数:210被引数:1.2万
H
Hong Chen
H 指数:19论文数:71被引数:5,761
A
Aiyun Wen
H 指数:16论文数:37被引数:1,197
M
Martin Jastroch
H 指数:52论文数:233被引数:1.1万
J
Jonathan J. Ruprecht
H 指数:24论文数:53被引数:2,718
H
Hyo‐Bum Kwak
H 指数:34论文数:145被引数:3,683
B
Bo Zhu
H 指数:34论文数:165被引数:3,573
S
Scott W. Wong
H 指数:40论文数:143被引数:6,319
S
Sudarshan Bhattacharjee
H 指数:10论文数:34被引数:325