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J

Jürgen Scheller

heinrich heine university

68H指数
282论文数
2.1W被引数
收录论文 165
发表时间
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SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1SIRT4通过ULK1正向调控自噬，但与HDAC6和OPA1无关。
errFEBS Open Bio
IF2.3
err2025-11-20
err0
errOAAI
errIsabell Lehmkuhl; Khawar Amin; Lydia Gabriel; Nils Hampel; Afshin Iram; Julia Hesse; Constanze Wiek; Jasmin Thuy Vy Nguyen; Helmut Hanenberg; Jürgen Scheller; M. Reza Ahmadian; Björn Stork; Doreen M. Floss; Roland P. Piekorz
err分享
err收藏
iBody-mediated tuning of synthetic cytokine receptor activation via rational nanobody interface engineeringiBody介导的合成细胞因子受体活性的理性纳米抗体界面工程调控
errmAbs
IF7.3
err2025-09-25
err0
errOAAI
errRichard Kunze; Fabian Navratil; Joana Beichert; Felix Geyer; Doreen M. Floss; Harald Kolmar; Jürgen Scheller; Silke Pudewell
err分享
err收藏
Targeting the major pro-inflammatory interleukin-6-type cytokine receptor gp130 by antagonistic single domain antibodies靶向主要促炎白细胞介素-6型细胞因子受体gp130的抗性单域抗体
errFrontiers in Immunology
IF5.9
err2025-08-15
err0
errOAAI
errSilke Pudewell†; Julia Heuser†; Inna Dorogobed; Britta Lipinski; Thi Hong Hue Tran; Pia Metzenmacher; Richard Kunze; Felix Geyer; Stefan Zielonka; Doreen M. Floss; Harald Kolmar; Jens M. Moll; Jürgen Scheller
err分享
err收藏
An engineered palivizumab IgG2 subclass for synthetic gp130 and fas-mediated signaling
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-03-01
err0
errOAAI
errWittich, Christoph; Ettich, Julia; Hertell, Marcel; Roy, Biswadeep Ghosh; Xu, Haifeng C.; Floss, Doreen M.; Lang, Philipp A.; Scheller, Juergen
err分享
err收藏
Synthetic trimeric interleukin-6 receptor complexes with a STAT3 phosphorylation dominated activation profile
errCYTOKINE
IF3.7
err2024-12-01
err0
errOAAI
errSeibel, Christiane; Pudewell, Silke; Rafii, Puyan; Ettich, Julia; Weitz, Hendrik T.; Lang, Alexander; Petzsch, Patrick; Koehrer, Karl; Floss, Doreen M.; Scheller, Juergen
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Interleukin-11 receptor is an alternative α-receptor for interleukin-6 and the chimeric cytokine IC7
errFEBS JOURNAL
IF4.2
err2024-10-29
err3
errOAAI
errWeitz, Hendrik T.; Ettich, Julia; Rafii, Puyan; Wittich, Christoph; Schultz, Laura; Frank, Nils C.; Heise, Denise; Krusche, Matthias; Lokau, Juliane; Garbers, Christoph; Behnke, Kristina; Floss, Doreen M.; Kolmar, Harald; Moll, Jens M.; Scheller, Juergen
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A refined TTC assay precisely detects cardiac injury and cellular viability in the infarcted mouse heart
errSCIENTIFIC REPORTS
IF3.9
err2024-10-24
err0
errOAAI
errDing, Zheheng; Liu, Xueqing; Jiang, Hongyan; Zhao, Jianfeng; Temme, Sebastian; Bouvain, Pascal; Alter, Christina; Rafii, Puyan; Scheller, Juergen; Floegel, Ulrich; Zhu, Hongtao; Ding, Zhaoping
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Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-05-01
err2
errOAAI
errRafii, Puyan; Cruz, Patricia Rodrigues; Ettich, Julia; Seibel, Christiane; Padrini, Giacomo; Wittich, Christoph; Lang, Alexander; Petzsch, Patrick; Koehrer, Karl; Moll, Jens M.; Floss, Doreen M.; Scheller, Juergen
err分享
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Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes
errNATURE COMMUNICATIONS
IF15.7
err2024-02-05
err3
errOAAI
errGrosse-Segerath, Linda; Follert, Paula; Behnke, Kristina; Ettich, Julia; Buschmann, Tobias; Kirschner, Philip; Hartwig, Sonja; Lehr, Stefan; Korf-Klingebiel, Mortimer; Eberhard, Daniel; Lehwald-Tywuschik, Nadja; Al-Hasani, Hadi; Knoefel, Wolfram Trudo; Heinrich, Stefan; Levkau, Bodo; Wollert, Kai C.; Scheller, Juergen; Lammert, Eckhard
err分享
err收藏
Respiratory syncytial virus-approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-11-01
err1
errOAAI
errEttich, Julia; Wittich, Christoph; Moll, Jens M.; Behnke, Kristina; Floss, Doreen M.; Reiners, Jens; Christmann, Andreas; Lang, Philipp A.; Smits, Sander H. J.; Kolmar, Harald; Scheller, Juergen
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err收藏
Bispecific soluble cytokine receptor-nanobody fusions inhibit Interleukin (IL-)6 trans-signaling and IL-12/23 or tumor necrosis factor (TNF) signaling
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-11-01
err4
errOAAI
errGesiorowski, Annika; Ettich, Julia; Werner, Julia; Wittich, Christoph; Pieper, Stephan; Padrini, Giacomo; Behnke, Kristina; Floss, Doreen M.; Lang, Philipp A.; Moll, Jens M.; Scheller, Juergen
err分享
err收藏
Exploring the landscape of synthetic IL-6-type cytokines
errFEBS JOURNAL
IF4.2
err2023-07-28
err4
errOAAI
errScheller, Jurgen; Ettich, Julia; Wittich, Christoph; Pudewell, Silke; Floss, Doreen M. M.; Rafii, Puyan
err分享
err收藏
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-06-21
err13
errOAAI
errNakhaei-Rad, Saeideh; Haghighi, Fereshteh; Bazgir, Farhad; Dahlmann, Julia; Busley, Alexandra Viktoria; Buchholzer, Marcel; Kleemann, Karolin; Schaenzer, Anne; Borchardt, Andrea; Hahn, Andreas; Koetter, Sebastian; Schanze, Denny; Anand, Ruchika; Funk, Florian; Kronenbitter, Annette Vera; Scheller, Juergen; Piekorz, Roland P.; Reichert, Andreas S.; Volleth, Marianne; Wolf, Matthew J.; Cirstea, Ion Cristian; Gelb, Bruce D.; Tartaglia, Marco; Schmitt, Joachim P.; Krueger, Martina; Kutschka, Ingo; Cyganek, Lukas; Zenker, Martin; Kensah, George; Ahmadian, Mohammad R.
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IL-6 in the infarcted heart is preferentially formed by fibroblasts and modulated by purinergic signaling
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-06-01
err15
errOAAI
errAlter, Christina; Henseler, Anne-Sophie; Owenier, Christoph; Hesse, Julia; Ding, Zhaoping; Lautwein, Tobias; Bahr, Jasmin; Hayat, Sikander; Kramann, Rafael; Kostenis, Eva; Scheller, Juergen; Schrader, Juergen
err分享
err收藏
Targeting IL-6 trans-signalling: past, present and future prospects靶向IL-6信号转导: 过去、现在和未来前景
errNATURE REVIEWS IMMUNOLOGY
IF60.9
err2023-04-17
err155
errOAAI
errRose-John, Stefan; Jenkins, Brendan J.; Garbers, Christoph; Moll, Jens M.; Scheller, Juergen
err分享
err收藏
Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-04-15
err8
errOAAI
errRafii, Puyan; Seibel, Christiane; Weitz, Hendrik T.; Ettich, Julia; Minafra, Anna Rita; Petzsch, Patrick; Lang, Alexander; Floss, Doreen M.; Behnke, Kristina; Koehrer, Karl; Moll, Jens M.; Scheller, Juergen
err分享
err收藏
Constitutive Activation of gp130 in T Cells Results in Senescence and Premature AgingT细胞中gp130的组成性激活导致衰老和过早衰老
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-04-14
err5
PREAI
errRafii, Puyan; Reusswig, Friedrich; Werner, Julia; Xu, Haifeng; Lang, Philpp A.; Rose-John, Stefan; Gorressen, Simone; Alter, Christina; Schrader, Jurgen; Herebian, Diran; Floss, Doreen M.; Elvers, Margitta; Piekorz, Roland P.; Scheller, Jurgen; Behnke, Kristina
err分享
err收藏
Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor β Heterodimer
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err39
errOAAI
errLarsen, Jakob Vejby; Hansen, Maria; Moller, Bjarne; Madsen, Peder; Scheller, Juergen; Nielsen, Morten; Petersen, Claus Munck
err分享
err收藏
Synthetic Deletion of the Interleukin 23 Receptor (IL-23R) Stalk Region Led to Autonomous IL-23R Homodimerization and Activation白细胞介素23受体 (IL-23R) 茎区的合成缺失导致自主IL-23R同源二聚化和激活
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-17
err19
errOAAI
errHummel, Thorben M.; Ackfeld, Theresa; Schoenberg, Marco; Ciupka, Gregor; Schulz, Falk; Oberdoerster, Anne; Groetzinger, Joachim; Scheller, Juergen; Floss, Doreen M.
err分享
err收藏
Interleukin 6 receptor is not directly involved in regulation of body weight in diet-induced obesity with and without physical exercise
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2022-10-27
err7
errOAAI
errMinafra, Anna Rita; Chadt, Alexandra; Rafii, Puyan; Al-Hasani, Hadi; Behnke, Kristina; Scheller, Juergen
err分享
err收藏

研究方向

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合作学者
合作期刊
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Stefan Schreiber
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H 指数: 142 · 论文数: 1.5K
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Philip Rosenstiel
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