logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
A

Anna Aagaard

astrazeneca
H指数:27
被引数:1,891
浏览量:0

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Mineralocorticoid Receptor Antagonists With an Acylurea as a Key Polar Interaction Motif

以酰脲为关键极性相互作用基团的盐皮质激素受体拮抗剂

ChemMedChem
IF3.4
2026-04-300
PRE
Anneli Nordqvist; Bo Lindmark; Kenneth L. Granberg; Anna Aagaard; Louise Barlind; Marlene Fredenwall; Eva Hansson; Anders Hogner; Ida Ivarsson; Maria Johansson; Jan Lindberg; Dongmei Liu; Henrik Sörensen; Stefan Tångefjord; Lena William-Olsson; Yoseph Atilaw; Zhong-Qing Yuan; Krister Bamberg; Gavin O’Mahony; Karl Edman
Identification and optimisation of a pyrimidopyridone series of IRAK4 inhibitors

嘧啶并吡啶酮系列IRAK4抑制剂的鉴定和优化

BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2022-06-012
PRE
Cumming, Iain A.; Degorce, Sebastien L.; Aagaard, Anna; Braybrooke, Erin L.; Davies, Nichola L.; Diene, Coura R.; Eatherton, Andrew J.; Felstead, Hannah R.; Groombridge, Sam D.; Lenz, Eva M.; Li, Yunxia; Nai, Youfeng; Pearson, Stuart; Robb, Graeme R.; Scott, James S.; Steward, Oliver R.; Wu, Chengyan; Xue, Yafeng; Zhang, Lanping; Zhang, Yanxiu
AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-08-3111
PRE
Narjes, Frank; Llinas, Antonio; von Berg, Stefan; Jirholt, Johan; Lever, Sarah; Pehrson, Rikard; Collins, Mia; Malmberg, Anna; Svanberg, Petter; Xue, Yafeng; Olsson, Roine, I; Malmberg, Jesper; Hughes, Glyn; Hossain, Nafizal; Grindebacke, Hanna; Leffler, Agnes; Krutrok, Nina; Back, Elisabeth; Ramnegard, Marie; Lepisto, Matti; Thunberg, Linda; Aagaard, Anna; McPheat, Jane; Hansson, Eva L.; Chen, Rongfeng; Xiong, Yao; Hansson, Thomas G.
Improving metabolic stability and removing aldehyde oxidase liability in a 5-azaquinazoline series of IRAK4 inhibitors
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2020-12-014
PREAI
Degorce, Sebastien L.; Aagaard, Anna; Anjum, Rana; Cumming, Iain A.; Diene, Coura R.; Fallan, Charlene; Johnson, Tony; Leuchowius, Karl-Johan; Orton, Alexandra L.; Pearson, Stuart; Robb, Graeme R.; Rosen, Alan; Scarfe, Graeme B.; Scott, James S.; Smith, James M.; Steward, Oliver R.; Terstiege, Ina; Tucker, Michael J.; Turner, Paul; Wilkinson, Stephen D.; Wrigley, Gail L.; Xue, Yafeng
Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2019-05-2921
OAAI
von Berg, Stefan; Xue, Yafeng; Collins, Mia; Llinas, Antonio; Olsson, Roine I.; Halvarsson, Torbjorn; Lindskog, Maria; Malmberg, Jesper; Jirholt, Johan; Krutrok, Nina; Ramnegard, Marie; Brannstrom, Marie; Lundqvist, Anders; Lepisto, Matti; Aagaard, Anna; McPheat, Jane; Hansson, Eva L.; Chen, Rongfeng; Xiong, Yao; Hansson, Thomas G.; Narjes, Frank
Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-12-3119
PREAI
Granberg, Kenneth L.; Yuan, Zhong-Qing; Lindmark, Bo; Edman, Karl; Kajanus, Johan; Hogner, Anders; Malmgren, Marcus; O'Mahony, Gavin; Nordqvist, Anneli; Lindberg, Jan; Tangefjord, Stefan; Kossenjans, Michael; Lofberg, Christian; Branalt, Jonas; Liu, Dongmei; Selmi, Nidhal; Nikitidis, Grigorios; Nordberg, Peter; Hayen, Ahlke; Aagaard, Anna; Hansson, Eva; Hermansson, Majlis; Ivarsson, Ida; Jansson-Lofmark, Rasmus; Karlsson, Ulla; Johansson, Ulrika; William-Olsson, Lena; Hartleib-Geschwindner, Judith; Bamberg, Krister
Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-08-1031
PREAI
Narjes, Frank; Xue, Yafeng; von Berg, Stefan; Malmberg, Jesper; Llinas, Antonio; Olsson, Rome, I; Jirholt, Johan; Grindebacke, Hanna; Leffler, Agnes; Hossain, Nafizal; Lepisto, Matti; Thunberg, Linda; Leek, Hanna; Aagaard, Anna; McPheat, Jane; Hansson, Eva L.; Back, Elisabeth; Tangefjord, Stefan; Chen, Rongfeng; Yao Xiong; Ge Hongbin; Hansson, Thomas G.
Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo
SCIENTIFIC REPORTS
IF3.9
2016-12-20107
OAAI
Dobson, Claire L.; Devine, Paul W. A.; Phillips, Jonathan J.; Higazi, Daniel R.; Lloyd, Christopher; Popovic, Bojana; Arnold, Joanne; Buchanan, Andrew; Lewis, Arthur; Goodman, Joanne; van der Walle, Christopher F.; Thornton, Peter; Vinall, Lisa; Lowne, David; Aagaard, Anna; Olsson, Lise-Lotte; Wollberg, Anna Ridderstad; Welsh, Fraser; Karamanos, Theodoros K.; Pashley, Clare L.; Iadanza, Matthew G.; Ranson, Neil A.; Ashcroft, Alison E.; Kippen, Alistair D.; Vaughan, Tristan J.; Radford, Sheena E.; Lowe, David C.
Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity

基于结构的盐皮质激素受体拮抗剂药物设计探索氧类固醇受体选择性

CHEMMEDCHEM
IF3.4
2016-12-1511
OAAI
Nordqvist, Anneli; O'Mahony, Gavin; Friden-Saxin, Maria; Fredenwall, Marlene; Hogner, Anders; Granberg, Kenneth L.; Aagaard, Anna; Backstrom, Stefan; Gunnarsson, Anders; Kaminski, Tim; Xue, Yafeng; Dellsen, Anita; Hansson, Eva; Hansson, Pia; Ivarsson, Ida; Karlsson, Ulla; Bamberg, Krister; Hermansson, Majlis; Georgsson, Jennie; Lindmark, Bo; Edman, Karl

研究方向

暂未获取到该数据
Y
Yafeng Xue
H 指数:33论文数:77被引数:3,260
E
Eva Hansson
H 指数:17论文数:40被引数:674
P
Peter Brzezinski
H 指数:55论文数:295被引数:1.1万
F
Frank Narjes
H 指数:33论文数:99被引数:2,930
Y
Yao Xiong
H 指数:20论文数:73被引数:1,446
J
James S. Scott
H 指数:51论文数:350被引数:8,478
J
Jane McPheat
H 指数:17论文数:24被引数:795
K
Krister Bamberg
H 指数:27论文数:62被引数:4,476
T
T. Hansson
H 指数:19论文数:51被引数:1,175
R
Rongfeng Chen
H 指数:25论文数:129被引数:2,168