Patrice Le Pape - Publications, H-index & Citations

Patrice Le Pape

institut agro dijon and inrae and université bourgogne europe and chu dijon bourgogne

38H指数

224论文数

4.5K被引数

收录论文 73

发表时间

A new MRR1 gain-of-function mutation involved in cross-resistance to antifungal agents in the fungal priority pathogen Candida parapsilosis 一种新型MRR1获得功能突变参与真菌优先病原体近平滑念珠菌对抗真菌剂的交叉耐药性

Medical Mycology

IF2.3

2026-09-04

PREAI

Manon Cadeau; José Rivaldo de Lima; Alina Marcela Sabou; Estelle Robert; Patrice Le Pape; Isabelle Ourliac-Garnier; Florent Morio⁠

Immunological fitness of echinocandin-resistant Nakaseomyces glabratus (former Candida glabrata): The impact on the management of candidemia 棘白菌素耐药的 Nakaseomyces glabratus（前称 Candida glabrata）的免疫适应性：对念珠菌血症管理的影响

Virulence

IF5.4

2026-05-19

OAAI

Louise Basmaciyan; Nidia Alvarez-Rueda; Delphine Aldebert; Hafsa Sahnouni; Cecile Garnaud; Delphine Patarot; Amandine Ducreux; Fabienne Bon; Pascale Winckler; Patrice Le Pape; Murielle Cornet; Frédéric Dalle

Multi-fungicide resistance in both clinical and environmental isolates of the human fungal pathogen Aspergillus fumigatus 人类真菌病原体Aspergillus fumigatus在临床和环境分离株中的多真菌素抗性

MEDICAL MYCOLOGY

IF2.3

2025-12-01

PREAI

Hartuis, Sophie; Robert, Manon; Chouaki, Taieb; Morio, Florent; Alvarez-Moreno, Carlos Arturo; Le pape, Patrice; Lavergne, Rose-Anne

A one health perspective on Diutina catenulata: Phenotypic traits, stress sensitivity, and virulence across diverse isolates 从“一种健康”视角看Diutina catenulata：表型特征、应激敏感性和毒力在多样化分离株中的表现

JOURNAL DE MYCOLOGIE MEDICALE

IF0

2025-10-01

OAAI

de Albuquerque, Ianca Karine Prudencio; Morio, Florent; Albassier, Marjorie; Baron, Luc; Duchesne, Lea; Le Pape, Patrice; Ourliac-Garnier, Isabelle

Hyperinfection with Anisakis simplex sensu stricto: observations from a cluster of two cases in France 狭义似鲔线虫（Anisakis simplex sensu stricto）重度感染：来自法国两例聚集性病例的观察

Food and Waterborne Parasitology

IF3.1

2025-08-29

OAAI

Manon Robert; Maureen Duflot; Fakhri Jeddi; Carelle Koudougou; Louise Durand; Florent Morio; Mélanie Gay; Patrice Le Pape; Rose-Anne Lavergne

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1; 2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy 以药效团为指导对靶向酪蛋白激酶1的抗利什曼原虫治疗中具有潜力的咪唑并[1; 2-a]吡嗪衍生物进行先导化合物CTN1122的优化设计

RSC Med. Chem.

IF3.6

2025-08-14

PREAI

Lhana Tisseur; Cédric Logé; Sandrine Cojean; Khadidiatou Gassama; Lilian Karcher; Fabrice Pagniez; Christian Cavé; Guillaume Bernadat; Philippe M. Loiseau; Stéphane Bach; Jérôme Thiéfaine; Justine Bonnet; Carine Picot; Christophe Tomasoni; Olivier Leclercq; Blandine Baratte; Thomas Robert; Patrice Le Pape; Najma Rachidi; Marc-Antoine Bazin; Pascal Marchand

Synthesis and Biological Evaluation of Itraconazole Derivatives: Design in an Old Scaffold 伊曲康唑衍生物的合成与生物活性评价：基于古老骨架的设计

Inorganic Chemistry

IF4.7

2025-07-29

PREAI

Shuai Zhong; Apollonia Kalamatianou; Gonzalo Scalese; Cillian O’Beirne; Marta Redrado; Olivier Blacque; Carine Picot; Christophe Tomasoni; Cédric Logé; Marjorie Albassier; Isabelle Ourliac-Garnier; Fabrice Pagniez; Patrice Le Pape; Leticia Pérez-Díaz; Dinorah Gambino; Marcelo A. Comini; Kevin Cariou; Gilles Gasser

Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition 研究基于咪唑并 [1，2-a] 吡嗪的命中化合物CTN1122的C2调节: 合成，体外抗利什曼蛋白活性，细胞毒性和酪蛋白激酶1抑制

CHEMMEDCHEM

IF3.4

2025-01-06

PREAI

Tisseur, Lhana; Cojean, Sandrine; Gassama, Khadidiatou; Loge, Cedric; Pagniez, Fabrice; Cave, Christian; Bernadat, Guillaume; Loiseau, Philippe M.; Bach, Stephane; Thiefaine, Jerome; Picot, Carine; Tomasoni, Christophe; Leclercq, Olivier; Baratte, Blandine; Robert, Thomas; Le Pape, Patrice; Rachidi, Najma; Bazin, Marc-Antoine; Marchand, Pascal

Precise genome editing underlines the distinct contributions of mutations in ERG11, ERG3, MRR1, and TAC1 genes to antifungal resistance in Candida parapsilosis 精确的基因组编辑强调了ERG11，ERG3，MRR1和TAC1基因突变对念珠菌的抗真菌抗性的独特贡献

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-04-16

PREAI

Hartuis, Sophie; Ourliac-Garnier, Isabelle; Robert, Estelle; Albassier, Marjorie; Duchesne, Lea; Beaufils, Clara; Kuhn, Josephine; Le Pape, Patrice; Morio, Florent

Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-11-27

OAAI

Lin, Yan; Jung, Hyeim; Bulman, Christina A.; Ng, James; Vinck, Robin; O'Beirne, Cillian; Zhong, Shuai; Moser, Matthew S.; Tricoche, Nancy; Peguero, Ricardo; Li, Robert W.; Urban Jr, Joseph F.; Le Pape, Patrice; Pagniez, Fabrice; Moretto, Marco; Weil, Tobias; Lustigman, Sara; Cariou, Kevin; Mitreva, Makedonka; Sakanari, Judy A.; Gasser, Gilles

Is the C-Terminal Domain an Effective and Selective Target for the Design of Hsp90 Inhibitors against Candida Yeast?

MICROORGANISMS

IF4.2

2023-11-22

OAAI

Rouges, Celia; Asad, Mohammad; Laurent, Adele D.; Marchand, Pascal; Le Pape, Patrice; Roemling, Ute

Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples

CLINICAL MICROBIOLOGY AND INFECTION

IF8.5

2023-02-01

OAAI

Nourrisson, Celine; Moniot, Maxime; Lavergne, Rose-Anne; Robert, Estelle; Bonnin, Virginie; Hagen, Ferry; Grenouillet, Frederic; Cafarchia, Claudia; Butler, Geraldine; Cassaing, Sophie; Sabou, Marcela; Le Pape, Patrice; Poirier, Philippe; Morio, Florent

Prototheca Infections and Ecology from a One Health Perspective

MICROORGANISMS

IF4.2

2022-04-29

OAAI

Libisch, Balazs; Picot, Carine; Ceballos-Garzon, Andres; Moravkova, Monika; Klimesova, Marcela; Telkes, Gabor; Chuang, Shih-Te; Le Pape, Patrice

Highly Conserved gsc1 Gene of Pneumocystis jirovecii in Patients with or without Prior Exposure to Echinocandins

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2022-01-18

OAAI

Bonnet, Pierre L.; Le Gal, Solene; Hoffmann, Claire, V; Morio, Florent; Diabira, Fouleymata; de Quelen, Athena; Curral, Guillaume; Negri, Steven; Cogulet, Virginie; Huon, Jean-Francois; Gregoire, Matthieu; Papon, Nicolas; Le Pape, Patrice; Bouchara, Jean-Philippe; Nevez, Gilles

Impact of TR34/L98H, TR46/Y121F/T289A and TR53 Alterations in Azole-Resistant Aspergillus fumigatus on Sterol Composition and Modifications after In Vitro Exposure to Itraconazole and Voriconazole

MICROORGANISMS

IF4.2

2022-01-04

OAAI

Lavergne, Rose-Anne; Albassier, Marjorie; Hardouin, Jean-Benoit; Alvarez-Moreno, Carlos; Pagniez, Fabrice; Morio, Florent; Le Pape, Patrice; Ourliac-Garnier, Isabelle

Genotypic, proteomic, and phenotypic approaches to decipher the response to caspofungin and calcineurin inhibitors in clinical isolates of echinocandin-resistant Candida glabrata

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IF3.6

2021-12-10

OAAI

Ceballos-Garzon, Andres; Monteoliva, Lucia; Gil, Concha; Alvarez-Moreno, Carlos; Vega-Vela, Nelson E.; Engelthaler, David M.; Bowers, Jolene; Le Pape, Patrice; Parra-Giraldo, Claudia M.

Confocal spectral microscopy, a non-destructive approach to follow contamination and biofilm formation of mCherry Staphylococcus aureus on solid surfaces

SCIENTIFIC REPORTS

IF3.9

2021-08-02

OAAI

Munir, Muhammad Tanveer; Maneewan, Nattar; Pichon, Julien; Gharbia, Mohammed; Oumarou-Mahamane, Ismael; Baude, Jessica; Thorin, Chantal; Lepelletier, Didier; Le Pape, Patrice; Eveillard, Matthieu; Irle, Mark; Pailhories, Helene; Aviat, Florence; Belloncle, Christophe; Federighi, Michel; Dubreil, Laurence

Characterisation of the antifungal effects of a plant-based compound, CIN-102, on the main septal filamentous fungi involved in human pathology

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE

IF3.2

2021-06-01

OAAI

D'Agostino, Maurine; Tesse, Nicolas; Lavergne, Rose Anne; Le Pape, Patrice; Bouchara, Jean Philippe; Frippiat, Jean Pol; Machouart, Marie; Debourgogne, Anne

The Extent of Aspergillosis in Critically Ill Patients With Severe Influenza Pneumonia: A Multicenter Cohort Study

CRITICAL CARE MEDICINE

IF6

2021-02-15

PREAI

Coste, Anne; Frerou, Aurelien; Raute, Anais; Couturaud, Francis; Morin, Jean; Egreteau, Pierre-Yves; Blanc, Francois-Xavier; Reignier, Jean; Tadie, Jean-Marc; Tran, Adissa; Pronier, Charlotte; Coste-Burel, Marianne; Nevez, Gilles; Gangneux, Jean-Pierre; Le Pape, Patrice; Ansart, Severine; Tonnelier, Jean-Marie; Bretonniere, Cedric; Aubron, Cecile

Multicenter Evaluation of an ELISA for the Detection of Cryptosporidium spp. Antigen in Clinical Human Stool Samples

MICROORGANISMS

IF4.2

2021-01-20

OAAI

Razakandrainibe, Romy; Merat, Celia; Kapel, Nathalie; Sautour, Marc; Guyot, Karine; Gargala, Gilles; Ballet, Jean-Jacques; Le Pape, Patrice; Dalle, Frederic; Favennec, Loic

研究方向