Timothy Wessler

University of North Carolina Chapel Hill

12H指数

36论文数

812被引数

收录论文 10

发表时间

Computational Modeling Insights into Extreme Heterogeneity in COVID-19 Nasal Swab Data

VIRUSES-BASEL

IF3.5

2023-12-30

OAAI

Zhang, Leyi; Cao, Han; Medlin, Karen; Pearson, Jason; Aristotelous, Andreas C.; Chen, Alexander; Wessler, Timothy; Forest, M. Gregory

Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration

ELIFE

IF0

2023-01-04

OAAI

Travis, Amanda M.; Manocha, Samiya; Willer, Jason R.; Wessler, Timothy S.; Skiba, Nikolai P.; Pearring, Jillian N.

Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection

BIOPHYSICAL JOURNAL

IF3.1

2022-05-01

OAAI

Chen, Alexander; Wessler, Timothy; Daftari, Katherine; Hinton, Kameryn; Boucher, Richard C.; Pickles, Raymond; Freeman, Ronit; Lai, Samuel K.; Forest, M. Gregory

A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes PBPK模型概括了抗PEG抗体介导的PEG脂质体清除的早期动力学

JOURNAL OF CONTROLLED RELEASE

IF11.5

2022-03-01

OAAI

Talkington, Anne M.; McSweeney, Morgan D.; Wessler, Timothy; Rath, Marielle K.; Li, Zibo; Zhang, Tao; Yuan, Hong; Frank, Jonathan E.; Forest, M. Gregory; Cao, Yanguang; Lai, Samuel K.

An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens

AAPS JOURNAL

IF3.7

2020-01-15

OAAI

Menezes, Bruna; Cilliers, Cornelius; Wessler, Timothy; Thurber, Greg M.; Linderman, Jennifer J.

Overcoming anti-PEG antibody mediated accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG 通过预输注高分子量游离PEG克服抗PEG抗体介导的PEG化脂质体的加速血液清除

JOURNAL OF CONTROLLED RELEASE

IF11.5

2019-10-01

OAAI

McSweeney, Morgan D.; Price, Lauren S. L.; Wessler, Timothy; Ciociola, Elizabeth C.; Herity, Leah B.; Piscitelli, Joseph A.; DeWalle, Alexander C.; Harris, Taylor N.; Chan, Andy K. P.; Saw, Ran Sing; Hu, Peiqi; Jennette, J. Charles; Forest, M. Gregory; Cao, Yanguang; Montgomery, Stephanie A.; Zamboni, William C.; Lai, Samuel K.

Modeling Barrier Properties of Intestinal Mucus Reinforced with IgG and Secretory IgA against Motile Bacteria

ACS INFECTIOUS DISEASES

IF3.8

2019-06-24

OAAI

Xu, Feifei; Newby, Jay M.; Schiller, Jennifer L.; Schroeder, Holly A.; Wessler, Timothy; Chen, Alex; Forest, M. Gregory; Lai, Samuel K.

Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology

IMMUNOLOGICAL REVIEWS

IF8.3

2018-08-11

208

OAAI

Cicchese, Joseph M.; Evans, Stephanie; Hult, Caitlin; Joslyn, Louis R.; Wessler, Timothy; Millar, Jess A.; Marino, Simeone; Cilfone, Nicholas A.; Mattila, Joshua T.; Linderman, Jennifer J.; Kirschner, Denise E.

A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors

NATURE COMMUNICATIONS

IF15.7

2017-10-10

OAAI

Newby, Jay; Schiller, Jennifer L.; Wessler, Timothy; Edelstein, Jasmine; Forest, M. Gregory; Lai, Samuel K.

Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus

ACS INFECTIOUS DISEASES

IF3.8

2015-12-02

OAAI

Wessler, Timothy; Chen, Alex; McKinley, Scott A.; Cone, Richard; Forest, M. Gregory; Lai, Samuel K.

研究方向