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A

Azadeh Shahsavar

Aarhus University
H指数:12
被引数:767

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Identification of Non-competitive and Reversible Inhibitors of Glycine Transporter 2: A Promising Non-opioid Therapeutic Strategy for Neuropathic Pain

鉴定甘氨酸转运蛋白2的非竞争性和可逆性抑制剂：一种有前景的非阿片类神经病理性疼痛治疗策略

Journal of Medicinal Chemistry
IF6.8
2026-04-010
PRE
Cioffi, Christopher L.; Pati, Tanmay K.; Lotsaris, Irina; Jayakumar, Srinivasan; Peiser-Oliver, Julian; Mahesh, Gaddam; Chater, Ryan P. Cantwell; Jayaraman, Aravindan; Frangos, Zachary J.; Suleria, Krishna; Evans, Sally; Kuppusamy, Ramajayam; Raja, Arun; Muthuraman, Parthasarathy; Mulmule, Jay; Mishra, Suman; Singh, Snigdha; Palanimuthu, Arunan; Michaelides, Michael; Shahsavar, Azadeh; Mohammadi, Sarasa; Vandenberg, Robert J.
A reversible allosteric inhibitor of GlyT2 for neuropathic pain without on-target side effects

GlyT2的可逆别构抑制剂在不产生靶向副作用的情况下缓解神经病理性疼痛

Nature Communications
IF15.7
2026-02-160
OA
Ryan P. Cantwell Chater; Julian Peiser-Oliver; Tanmay K. Pati; Ada S. Quinn; Irina Lotsaris; Zachary J. Frangos; Kristen E. Anderson; Anna E. Tischer; Billy J. Williams-Noonan; Karin R. Aubrey; Megan L. O’Mara; Michael Michaelides; Sarasa A. Mohammadi; Christopher L. Cioffi; Robert J. Vandenberg; Azadeh Shahsavar

研究方向

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