Lequn Li

Tongji Medical College

H指数:25

被引数:3,493

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GFI1 enhances MHC-I expression in tumor cells and augments tumor responsiveness to PD-1/PD-L1 inhibitors

GFI1增强肿瘤细胞中MHC-I的表达并提高肿瘤对PD-1/PD-L1抑制剂的响应性

cancer immunology, immunotherapy

IF0

2026-05-220

Proteasome inhibition by bortezomib augments the efficacy of anti-PD-L1 therapy against lung cancer

硼替佐米通过抑制蛋白酶体增强了抗PD-L1疗法对肺癌的治疗效果。

European Journal of Pharmacology

IF4.7

2026-02-230

PRE

IFN-γ-mediated suppression of ANGPT2-Tie2 in endothelial cells facilitates tumor vascular normalization during immunotherapy

IFN-γ介导的ANGPT2-Tie2在血管内皮细胞中的抑制，有助于免疫治疗期间肿瘤血管的归整化。

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-04-300

Analysis of tumor cell proliferation (Ki-67) and cell cycle regulator proteins in lung adenocarcinoma with different radiological subtypes

不同影像学亚型肺腺癌中肿瘤细胞增殖（Ki-67）和细胞周期调控蛋白的分析

RESPIRATORY RESEARCH

IF5

2025-04-130

Targeting PD-1 and CD85j can restore intratumoral CD4+ GzmB+ T-cell functions to combat MHC-II-expressing tumors

靶向PD-1和CD85j可以恢复肿瘤内CD4+ GzmB+ T细胞功能，以对抗表达MHC-II的肿瘤

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2025-04-010

Glutamine deprivation confers immunotherapy resistance by inhibiting IFN-γ signaling in cancer cells

谷氨酰胺剥夺通过抑制癌细胞中IFN-γ信号通路赋予免疫疗法抗性

PHARMACOLOGICAL RESEARCH

IF10.5

2025-03-010

OAAI

Differences in tumor angiogenesis and related factors between lung adenocarcinomas manifesting as pure ground glass opacity and solid nodules

肺腺癌表现为纯磨玻璃结节和实性结节之间的肿瘤血管生成及相关因素的差异

DISCOVER ONCOLOGY

IF2.9

2025-02-130

Type B thymomas in patients with myasthenia gravis display a distinctive pattern of αβ TCR and IL-7 receptor α expression on CD4+CD8+ thymocytes

重症肌无力患者的b型胸腺瘤在CD4 CD8胸腺细胞上显示出 α β TCR和IL-7受体 α 表达的独特模式

AUTOIMMUNITY

IF3.1

2024-05-090

Lung cancer cell-intrinsic IL-15 promotes cell migration and sensitizes murine lung tumors to anti-PD-L1 therapy

BIOMARKER RESEARCH

IF11.5

2024-04-190

OAAI

TGFb Antagonizes IFNg-Mediated Adaptive Immune Evasion via Activation of the AKT-Smad3-SHP1 Axis in Lung Adenocarcinoma

CANCER RESEARCH

IF16.6

2023-05-055

CD4+ Cytotoxic T Lymphocytes in Cancer Immunity and Immunotherapy

CD4细胞毒性T淋巴细胞在癌症免疫和免疫治疗中的作用

ADVANCED BIOLOGY

IF2.6

2022-10-0415

PRE

Knockdown of hnRNPA1 Promotes NSCLC Metastasis and EMT by Regulating Alternative Splicing of LAS1L exon 9

敲低hnRNPA1通过调控LAS1L外显子9的选择性剪接促进NSCLC转移和EMT

FRONTIERS IN ONCOLOGY

IF3.3

2022-06-238

OAAI

IFN-γ activates the tumor cell-intrinsic STING pathway through the induction of DNA damage and cytosolic dsDNA formation

ONCOIMMUNOLOGY

IF6.3

2022-03-0328

Immune Checkpoint Inhibitors in Hepatocellular Carcinoma: Current Progresses and Challenges

免疫检查点抑制剂在肝细胞癌中的研究进展与挑战

FRONTIERS IN ONCOLOGY

IF3.3

2021-10-2230

OAAI

IFN-γ-induced ER stress impairs autophagy and triggers apoptosis in lung cancer cells

ONCOIMMUNOLOGY

IF6.3

2021-08-1083

An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma

MOLECULAR CANCER RESEARCH

IF4.7

2021-03-2610

CD8+CD57+T cells exhibit distinct features in human non-small cell lung cancer

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2020-06-3032

OAAI

IL-10 suppresses IFN-γ-mediated signaling in lung adenocarcinoma

IL-10抑制肺腺癌中ifn-γ 介导的信号传导

CLINICAL AND EXPERIMENTAL MEDICINE

IF3.5

2020-04-187

PREAI

Estrogen promotes the metastasis of non-small cell lung cancer via estrogen receptor β by upregulation of Toll-like receptor 4 and activation of the myd88/NF-κB/MMP2 pathway

ONCOLOGY REPORTS

IF3.9

2020-04-0213

Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA)

循环肿瘤DNA (ctDNA) 高通量靶向DNA甲基化测序无创诊断早期肺癌

THERANOSTICS

IF13.3

2019-01-01172

OAAI

Lequn Li

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教育背景

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