Chikashi Toyoshima - Publications, H-index & Citations

Chikashi Toyoshima

University of Tokyo

52H指数

216论文数

1.3W被引数

收录论文 63

发表时间

Structure-activity relationship studies on iezoside, a highly potent Ca2+ ATPase inhibitor

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

IF3.8

2024-07-05

PREAI

Kurisawa, Naoaki; Teranuma, Kazuya; Noto, Akari; Iwasaki, Arihiro; Kabashima, Yoshiki; Nakajima, Rie; Toyoshima, Chikashi; Suenaga, Kiyotake

The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase C末端尾区作为塞子调节XKR8脂质扰酶的作用

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-01

OAAI

Sakuragi, Takaharu; Kanai, Ryuta; Otani, Mayumi; Kikkawa, Masahide; Toyoshima, Chikashi; Nagata, Shigekazu

Crystal structures of Na+,K+-ATPase reveal the mechanism that converts the K+-bound form to Na+-bound form and opens and closes the cytoplasmic gate

FEBS LETTERS

IF3

2023-07-06

OAAI

Kanai, Ryuta; Vilsen, Bente; Cornelius, Flemming; Toyoshima, Chikashi

Cryo-electron microscopy of Na+,K+-ATPase reveals how the extracellular gate locks in the E2•2K+ state

FEBS LETTERS

IF3

2022-07-06

OAAI

Kanai, Ryuta; Cornelius, Flemming; Vilsen, Bente; Toyoshima, Chikashi

Structural Determination, Total Synthesis, and Biological Activity of Iezoside, a Highly Potent Ca2+-ATPase Inhibitor from the Marine Cyanobacterium Leptochromothrix valpauliae

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-06-08

PREAI

Kurisawa, Naoaki; Iwasaki, Arihiro; Teranuma, Kazuya; Dan, Shingo; Toyoshima, Chikashi; Hashimoto, Masaru; Suenaga, Kiyotake

Cryoelectron microscopy of Na+,K+-ATPase in the two E2P states with and without cardiotonic steroids

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-04-05

OAAI

Kanai, Ryuta; Cornelius, Flemming; Vilsen, Bente; Toyoshima, Chikashi

The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-10-08

OAAI

Sakuragi, Takaharu; Kanai, Ryuta; Tsutsumi, Akihisa; Narita, Hirotaka; Onishi, Eriko; Nishino, Kohei; Miyazaki, Takuya; Baba, Takeshi; Kosako, Hidetaka; Nakagawa, Atsushi; Kikkawa, Masahide; Toyoshima, Chikashi; Nagata, Shigekazu

Binding of cardiotonic steroids to Na+,K+-ATPase in the E2P state

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-12-28

OAAI

Kanai, Ryuta; Cornelius, Flemming; Ogawa, Haruo; Motoyama, Kanna; Vilsen, Bente; Toyoshima, Chikashi

What ATP binding does to the Ca2+ pump and how nonproductive phosphoryl transfer is prevented in the absence of Ca2+

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-07-16

OAAI

Kabashima, Yoshiki; Ogawa, Haruo; Nakajima, Rie; Toyoshima, Chikashi

Mechanism of the E2 to E1 transition in Ca2+ pump revealed by crystal structures of gating residue mutants

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-11-27

OAAI

Tsunekawa, Naoki; Ogawa, Haruo; Tsueda, Junko; Akiba, Toshihiko; Toyoshima, Chikashi

Suppressor mutation analysis combined with 3D modeling explains cohesin's capacity to hold and release DNA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-05-07

OAAI

Xu, Xingya; Kanai, Ryuta; Nakazawa, Norihiko; Wang, Li; Toyoshima, Chikashi; Yanagida, Mitsuhiro

Distinct pH dependencies of Na+/K+ selectivity at the two faces of Na,K-ATPase

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-02-01

OAAI

Cornelius, Flemming; Tsunekawa, Naoki; Toyoshima, Chikashi

Crystal Structures of SERCA2a and SERCA2b

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Ogawa, Haruo; Kabashima, Yoshiki; Nakajima, Rie; Toyoshima, Chikashi

Large Scale Production of Mammalian Membrane Proteins Toward Determination of High-Resolution Structure

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

Ogawa, Haruo; Toyoshima, Chikashi

Mn2+ transport by Ca2+-ATPase of sarcoplasmic reticulum (vol 590, pg 2086, 2016)

FEBS LETTERS

IF3

2016-12-23

OAAI

Yonekura, Shin-Ichiro; Toyoshima, Chikashi

Mn2+ transport by Ca2+-ATPase of sarcoplasmic reticulum

FEBS LETTERS

IF3

2016-06-23

OAAI

Yonekura, Shin-Ichiro; Toyoshima, Chikashi

Kinetics by X-Ray Crystallography: Sequential Substitution of K+ Bound To Na+, K+-ATPase

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Ogawa, Haruo; Cornelius, Flemming; Hirata, Ayami; Toyoshima, Chikashi

Sequential substitution of K+ bound to Na+, K+-ATPase visualized by X-ray crystallography

NATURE COMMUNICATIONS

IF15.7

2015-08-10

OAAI

Ogawa, Haruo; Cornelius, Flemming; Hirata, Ayami; Toyoshima, Chikashi

Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca2+ pumps with a unique mode of binding

FEBS LETTERS

IF3

2015-05-06

OAAI

Morita, Maho; Ogawa, Haruo; Ohno, Osamu; Yamori, Takao; Suenaga, Kiyotake; Toyoshima, Chikashi

Electron crystallography of ultrathin 3D protein crystals: Atomic model with charges

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-02-17

144

OAAI

Yonekura, Koji; Kato, Kazuyuki; Ogasawara, Mitsuo; Tomita, Masahiro; Toyoshima, Chikashi

研究方向