Tomás González‐Hernández

universidad de la laguna

33H指数

103论文数

5.6K被引数

收录论文 23

发表时间

Dopamine Receptor D3 Induces Transient, mTORC1-Dependent Autophagy That Becomes Persistent, AMPK-Mediated, and Neuroprotective in Experimental Models of Huntington's Disease 多巴胺受体D3诱导短暂的、mTORC1依赖的自噬，该自噬在亨廷顿病实验模型中转变为持续性、AMPK介导的、具有神经保护作用的。

CELLS

IF5.2

2025-04-29

OAAI

Luis-Ravelo, Diego; Fumagallo-Reading, Felipe; Febles-Casquero, Alejandro; Lopez-Fernandez, Jonathan; Marcellino, Daniel J.; Gonzalez-Hernandez, Tomas

Random lasing as a sensing tool in brain samples of an animal model of Huntington's disease

APPLIED PHYSICS LETTERS

IF3.6

2022-09-23

PREAI

de Armas-Pillo, Sergio; Fumagallo-Reading, Felipe; Luis-Ravelo, Diego; Abdul-Jalbar, Beatriz; Gonzalez-Hernandez, Tomas; Lahoz, Fernando

Random Lasing Detection of Mutant Huntingtin Expression in Cells

SENSORS

IF3.5

2021-05-31

OAAI

de Armas-Rillo, Sergio; Fumagallo-Reading, Felipe; Luis-Ravelo, Diego; Abdul-Jalbar, Beatriz; Gonzalez-Hernandez, Tomas; Lahoz, Fernando

Prolonged dopamine D3 receptor stimulation promotes dopamine transporter ubiquitination and degradation through a PKC-dependent mechanism

PHARMACOLOGICAL RESEARCH

IF10.5

2021-03-01

PREAI

Luis-Ravelo, Diego; Fumagallo-Reading, Felipe; Castro-Hernandez, Javier; Barroso-Chinea, Pedro; Afonso-Oramas, Domingo; Febles-Casquero, Alejandro; Cruz-Muros, Ignacio; Salas-Hernandez, Josmar; Mesa-Infante, Virginia; Rodriguez-Nunez, Julia; Gonzalez-Hernandez, Tomas

DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis

AUTOPHAGY

IF14.3

2019-10-02

OAAI

Barroso-Chinea, Pedro; Luis-Ravelo, Diego; Fumagallo-Reading, Felipe; Castro-Hernandez, Javier; Salas-Hernandez, Josmar; Rodriguez-Nunez, Julia; Febles-Casquero, Alejandro; Cruz-Muros, Ignacio; Afonso-Oramas, Domingo; Abreu-Gonzalez, Pedro; Moratalla, Rosario; Millan, Mark J.; Gonzalez-Hernandez, Tomas

Long-term controlled GDNF over-expression reduces dopamine transporter activity without affecting tyrosine hydroxylase expression in the rat mesostriatal system

NEUROBIOLOGY OF DISEASE

IF5.6

2016-04-01

OAAI

Barroso-Chinea, Pedro; Cruz-Muros, Ignacio; Afonso-Oramas, Domingo; Castro-Hernandez, Javier; Salas-Hernandez, Josmar; Chtarto, Abdelwahed; Luis-Ravelo, Diego; Humbert-Claude, Marie; Tenenbaum, Liliane; Gonzalez-Hernandez, Tomas

Prolonged treatment with pramipexole promotes physical interaction of striatal dopamine D3 autoreceptors with dopamine transporters to reduce dopamine uptake

NEUROBIOLOGY OF DISEASE

IF5.6

2015-02-01

PREAI

Castro-Hernandez, Javier; Afonso-Oramas, Domingo; Cruz-Muros, Ignacio; Salas-Hernandez, Josmar; Barroso-Chinea, Pedro; Moratalla, Rosario; Millan, Mark J.; Gonzalez-Hernandez, Tomas

Neonatal Apneic Seizure of Occipital Lobe Origin: Continuous Video-EEG Recording

PEDIATRICS

IF6.4

2012-06-01

PREAI

Castro Conde, Jose Ramon; Gonzalez-Hernandez, Tomas; Gonzalez Barrios, Desire; Gonzalez Campo, Candelaria

Differential N termini in epithelial Na+ channel δ-subunit isoforms modulate channel trafficking to the membrane 上皮Na通道 δ 亚基同工型中的差异N末端调节通道向膜的运输

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2012-03-15

PREAI

Wesch, Diana; Althaus, Mike; Miranda, Pablo; Cruz-Muros, Ignacio; Fronius, Martin; Gonzalez-Hernandez, Tomas; Clauss, Wolfgang G.; Alvarez de la Rosa, Diego; Giraldez, Teresa

The dopamine transporter is differentially regulated after dopaminergic lesion

NEUROBIOLOGY OF DISEASE

IF5.6

2010-12-01

PREAI

Afonso-Oramas, Domingo; Cruz-Muros, Ignacio; Barroso-Chinea, Pedro; Alvarez de la Rosa, Diego; Castro-Hernandez, Javier; Salas-Hernandez, Josmar; Giraldez, Teresa; Gonzalez-Hernandez, Tomas

The neuronal-specific SGK1.1 kinase regulates δ-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling 神经元特异性SGK1.1激酶独立于PY基序调节 δ-上皮Na通道，并将其与磷脂酶C信号传导偶联

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2010-10-01

PREAI

Wesch, Diana; Miranda, Pablo; Afonso-Oramas, Domingo; Althaus, Mike; Castro-Hernandez, Javier; Dominguez, Jaime; Morty, Rory E.; Clauss, Wolfgang; Gonzalez-Hernandez, Tomas; Alvarez de la Rosa, Diego; Giraldez, Teresa

Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson's disease

NEUROBIOLOGY OF DISEASE

IF5.6

2009-12-01

PREAI

Afonso-Oramas, Domingo; Cruz-Muros, Ignacio; de la Rosa, Diego Alvarez; Abreu, Pedro; Giraldez, Teresa; Castro-Hernandez, Javier; Salas-Hernandez, Josmar; Lanciego, Jose L.; Rodriguez, Manuel; Gonzalez-Hernandez, Tomas

Aging effects on the dopamine transporter expression and compensatory mechanisms

NEUROBIOLOGY OF AGING

IF3.5

2009-06-01

PREAI

Cruz-Muros, Ignacio; Afonso-Oramas, Domingo; Abreu, Pedro; Perez-Delgado, Maria A.; Rodriguez, Manuel; Gonzalez-Hernandez, Tomas

Deglycosylation and subcellular redistribution of VMAT2 in the mesostriatal system during normal aging

NEUROBIOLOGY OF AGING

IF3.5

2008-11-01

PREAI

Cruz-Muros, Ignacio; Afonso-Oramas, Domingo; Abreu, Pedro; Rodriguez, Manuel; Carmen Gonzalez, M.; Gonzalez-Hernandez, Tomas

Nitric oxide synthase expression in the cerebral cortex of patients with epilepsy 一氧化氮合酶在癫痫患者大脑皮层中的表达

EPILEPSIA

IF6.6

2007-11-05

OAAI

González-Hernández, T; García-Marín, V; Pérez-Delgado, MDM; González-González, ML; Rancel-Torres, N; González-Feria, L

Substantia nigra osmoregulation: taurine and ATP involvement 黑质渗透压调节: 牛磺酸和ATP参与

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2007-05-01

PREAI

Morales, Ingrid; Dopico, Jose G.; Sabate, Magdalena; Gonzalez-Hernandez, Tomas; Rodriguez, Manuel

Heterogeneous dopamine neurochemistry in the striatum: The fountain-drain matrix

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2006-10-01

PREAI

Rodriguez, Manuel; Morales, Ingrid; Gomez, Isabel; Gonzalez, Sergio; Gonzalez-Hernandez, Tomas; Gonzalez-Mora, Jose Luis

Tetrahydrobiopterin stimulates L-DOPA release from striatal tissue

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2006-07-01

PREAI

Abreu-Gonzalez, P.; Gonzalez-Hernandez, T.; Afonso-Oramas, D.; Cruz-Muros, I.; Barroso-Chinea, P.; Gonzalez, M. C.

Alcoholic myopathy:: Lack of effect of zinc supplementation

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2005-09-01

PREAI

Castellón, MCD; González-Reimers, E; López-Lirola, A; Olivera, RM; Santolaria-Fernández, F; Galindo-Martín, L; Abreu-González, P; González-Hernández, T

Response of the GABAergic and dopaminergic mesostriatal projections to the lesion of the contralateral dopaminergic mesostriatal pathway in the rat

MOVEMENT DISORDERS

IF7.6

2004-08-30

PREAI

González-Hernández, T; Barroso-Chinea, P; Rodríguez, M

研究方向