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Takashi Ikejima

Shenyang Pharmaceutical University

55H指数
287论文数
1.1W被引数
收录论文 135
发表时间
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Type I collagen alleviates tBHP-induced senescence in murine hippocampal neuronal HT22 cells through an F-actin/ferroptosis pathwayI型胶原蛋白通过F-肌动蛋白/铁死亡通路缓解叔丁基过氧化氢诱导的鼠海马神经元HT22细胞衰老
errConnective Tissue Research
IF2.1
err2026-08-06
err0
PREAI
errXiaoling Wang; Xin Li; Ling Ling; Toshihiko Hayashi; Kazunori Mizuno; Shunji Hattori; Hitomi Fujisaki; Weiwei Liu; Takashi Ikejima
err分享
err收藏
Silibinin restricts mitochondria-associated inflammatory pathways in LPS-stimulated murine microglia BV2 through TREM2西利宾抑制LPS刺激的小鼠小胶质细胞BV2中与线粒体相关的炎症通路，其作用机制是通过TREM2。
errCellular Immunology
IF2.9
err2026-04-06
err0
PREAI
errWenhui Chen; Xiaoling Wang; Panwen Liu; Yu Kang; Toshihiko Hayashi; Kazunori Mizuno; Shunji Hattori; Hitomi Fujisaki; Weiwei Liu; Takashi Ikejima
err分享
err收藏
Silibinin inhibits F-actin assembly leading to G2/M cell cycle arrest in human breast cancer cells − is targeted therapy on the horizon?西利宾抑制F-肌动蛋白组装，导致人乳腺癌细胞G2/M期细胞周期阻滞——靶向治疗是否即将到来？
errBiochemical Pharmacology
IF5.6
err2025-12-04
err0
PREAI
errJianing Fu; Siyu Liu; Ruxiao Zhao; Weiwei Liu; Toshihiko Hayashi; Kazunori Mizuno; Shunji Hattori; Hitomi Fujisaki; Takashi Ikejima
err分享
err收藏
High glucose induces hippocampal neuron impairment through the SKP1/COX7C pathway: A potential mechanism for perimenopausal depression高血糖通过SKP1/COX7C通路诱导海马神经元损伤：围绝经期抑郁的潜在机制
errActa Pharmaceutica Sinica B
IF14.6
err2025-09-06
err0
errOAAI
errZiqi Wang; Zhiyuan Liu; Sijia Feng; Xintong Song; Dequan Liu; Ning Ma; Xinyue Zhang; Weiwei Liu; Dan Ohtan Wang; Xiaoling Liu; Takashi Ikejima
err分享
err收藏
Gelatin enhances bacteria-phagocytosis via a ROS-mitochondria-STING axis in differentiated human macrophage-like U937 cells明胶通过ROS-线粒体-STING轴增强分化的人巨噬细胞样U937细胞的细菌吞噬作用
errMolecular Immunology
IF3
err2025-08-14
err0
PREAI
errXiaoli Sun; Meiling Li; Yuhang Ma; Kaihui Chen; Shunuo Jiang; Toshihiko Hayashi; Kikuji Itoh; Kazunori Mizuno; Shunji Hattori; Hitomi Fujisaki; Weiwei Liu; Takashi Ikejima
err分享
err收藏
AMPK impairment caused by gelatin disturbs mitochondrial dynamics leading to enhanced phagocytosis of bacteria in PMA-stimulated U937 cells明胶引起的AMPK功能障碍扰乱了线粒体动力学，导致PMA刺激的U937细胞中细菌吞噬作用增强。
errCellular Signalling
IF3.7
err2025-07-11
err0
PREAI
errKaihui Chen; Xiaoli Sun; Yue Feng; Shunuo Jiang; Hayashi Toshihiko; Itoh Kikuji; Mizuno Kazunori; Shunji Hattori; Hitomi Fujisaki; Weiwei Liu; Takashi Ikejima
err分享
err收藏
Inhibition of YAP/TAZ pathway contributes to the cytotoxicity of silibinin in MCF-7 and MDA-MB-231 human breast cancer cells
errCELLULAR SIGNALLING
IF3.7
err2024-07-01
err0
PREAI
errFu, Jianing; Liu, Weiwei; Liu, Siyu; Zhao, Ruxiao; Hayashi, Toshihiko; Zhao, Haina; Xiang, Yinlanqi; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Collagen I protects human keratinocytes HaCaT against UVB injury via restoring PINK1/parkin-mediated mitophagy
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2024-03-01
err3
PREAI
errZhu, Yuying; Xiang, Wendie; He, Sijun; San, Zhao; Liu, Weiwei; Wu, Jin; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
DNA damage-triggered activation of cGAS-STING pathway induces apoptosis in human keratinocyte HaCaT cells (vol 131 ,6222, 2021)
errMOLECULAR IMMUNOLOGY
IF3
err2023-12-01
err0
errOAAI
errLi, Can; Liu, Weiwei; Wang, Fang; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Silibinin ameliorates STING-mediated neuroinflammation via downregulation of ferroptotic damage in a sporadic Alzheimer's disease model
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2023-08-01
err16
PREAI
errLiu, Panwen; Chen, Wenhui; Kang, Yu; Wang, Chenkang; Wang, Xiaoling; Liu, Weiwei; Hayashi, Toshihiko; Qiu, Zhiyue; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2023-07-01
err19
PREAI
errDu, Qingqing; Wu, Xiaoyun; Ma, Kai; Liu, Weiwei; Liu, Panwen; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Inhibition of GluN2B pathway is involved in the neuroprotective effect of silibinin on streptozotocin-induced Alzheimer's disease models
errPHYTOMEDICINE
IF8.3
err2023-01-01
err7
PREAI
errLiu, Panwen; Wang, Chenkang; Chen, Wenhui; Kang, Yu; Liu, Weiwei; Qiu, Zhiyue; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axisI型胶原蛋白通过yap-mtor-自噬轴减少前脂肪细胞3T3-L1脂肪形成过程中的脂质积累
errBIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
IF3.3
err2022-09-01
err8
PREAI
errGao, Yanfang; Ma, Kai; Kang, Yu; Liu, Weiwei; Liu, Xiaoling; Long, Xinyu; Hayashi, Toshihiko; Hattori, Shunji; Mizuno, Kazunori; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Bi-phasic effect of gelatin in myogenesis and skeletal muscle regeneration
errDISEASE MODELS & MECHANISMS
IF3.3
err2021-12-24
err3
errOAAI
errLiu, Xiaoling; Zu, Er; Chang, Xinyu; Ma, Xiaowei; Wang, Ziqi; Song, Xintong; Li, Xiangru; Yu, Qing; Kamei, Ken-ichiro; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi; Wang, Dan Ohtan
err分享
err收藏
Silibinin relieves UVB-induced apoptosis of human skin cells by inhibiting the YAP-p73 pathway
errACTA PHARMACOLOGICA SINICA
IF8.4
err2021-12-15
err16
errOAAI
errLiu, Wei-wei; Wang, Fang; Li, Can; Song, Xiao-yu; Otkur, Wuxiyar; Zhu, Yu-ying; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Collagen type 1 enhances cell growth and insulin biosynthesis in rat pancreatic cells
errJOURNAL OF MOLECULAR ENDOCRINOLOGY
IF3.8
err2021-10-01
err6
errOAAI
errZhu, Yingying; Liu, Weiwei; Chen, Shuaigao; Xu, Fanxing; Zhang, Luxin; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors
errJOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
IF3.7
err2021-03-01
err13
PREAI
errLiu, Weiwei; Wang, Fang; Li, Can; Otkur, Wuxiyar; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Onodera, Satoshi; Ikejima, Takashi
err分享
err收藏
DNA damage-triggered activation of cGAS-STING pathway induces apoptosis in human keratinocyte HaCaT cells
errMOLECULAR IMMUNOLOGY
IF3
err2021-03-01
err65
PREAI
errLi, Can; Liu, Weiwei; Wang, Fang; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Fujisaki, Hitomi; Ikejima, Takashi
err分享
err收藏
Natural flavonoid silibinin promotes the migration and myogenic differentiation of murine C2C12 myoblasts via modulation of ROS generation and down-regulation of estrogen receptor α expression
errMOLECULAR AND CELLULAR BIOCHEMISTRY
IF3.7
err2020-08-12
err6
PREAI
errLong, Xinyu; Gao, Yanfang; Liu, Weiwei; Liu, Xiaoling; Hayashi, Toshihiko; Mizuno, Kazunori; Hattori, Shunji; Ikejima, Takashi
err分享
err收藏
Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells雌激素受体参与水飞蓟宾引起的人乳腺癌MCF-7细胞凋亡诱导因子的核转位
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2020-08-01
err7
PREAI
errLiu, Weiwei; Ji, Yachao; Sun, Yu; Si, Lingling; Fu, Jianing; Hayashi, Toshihiko; Onodera, Satoshi; Ikejima, Takashi
err分享
err收藏

研究方向

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合作学者
合作期刊
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