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Liangxing Wu

Texas A&M University System
H指数:15
被引数:1,248

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Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-02-072
PRE
Hummel, Joshua R.; Xiao, Kai-Jiong; Yang, Jeffrey C.; Epling, Leslie B.; Mukai Ken; Ye, Qinda; Xu, Meizhong; Qian, Dingquan; Huo, Lu; Weber, Michael; Roman, Valerie; Lo, Yvonne; Drake, Katherine; Stump, Kristine; Covington, Maryanne; Kapilashrami, Kanishk; Zhang, Guofeng; Ye, Min; Diamond, Sharon; Yeleswaram, Swamy; Macarron, Ricardo; Deller, Marc C.; Wee, Susan; Kim, Sunkyu; Wang, Xiaozhao; Wu, Liangxing; Yao, Wenqing
Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2

发现新型吡唑并嘧啶作为ALK2的有效，选择性和口服生物利用度抑制剂

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2022-06-226
OA
Nguyen, Minh H.; Atasoylu, Onur; Wu, Liangxing; Kapilashrami, Kanishk; Pusey, Michelle; Gallagher, Karen; Lai, Cheng-Tsung; Zhao, Peng; Barbosa, Joseph; Liu, Kai; He, Chunhong; Zhang, Colin; Styduhar, Evan D.; Witten, Michael R.; Chen, Yaoyu; Lin, Luping; Yang, Yan-ou; Covington, Maryanne; Diamond, Sharon; Yeleswaram, Swamy; Yao, Wenqing
Discovery of Pemigatinib: A Potent and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-07-1645
PREAI
Wu, Liangxing; Zhang, Colin; He, Chunhong; Qian, Dingquan; Lu, Liang; Sun, Yaping; Xu, Meizhong; Zhuo, Jincong; Liu, Phillip C. C.; Klabe, Ronald; Wynn, Richard; Covington, Maryanne; Gallagher, Karen; Leffet, Lynn; Bowman, Kevin; Diamond, Sharon; Koblish, Holly; Zhang, Yue; Soloviev, Maxim; Hollis, Gregory; Burn, Timothy C.; Scherle, Peggy; Yeleswaram, Swamy; Huber, Reid; Yao, Wenqing
The FAD-directed LSD1 specific inhibitor, INCB059872, inhibits cell migration and metastasis by suppressing premetastatic niche formation in a spontaneous metastasis mouse model
CANCER RESEARCH
IF16.6
2018-07-015
PRE
Lee, Sang Hyun; Diamond, Melody; Chadderton, Antony; Liu, Huiqing; Volgina, Alla; Roman, Valerie; Weber, Michael; He, Chunhong; Stewart, Rebecca; Hertel, Denise; Liu, Phillip; Wu, Liangxing; Oliver, Julian; Yeleswaram, Swamy; Roberts, Alan; Yao, Wenqing; Hollis, Gregory; Huber, Reid; Scherle, Peggy; Ruggeri, Bruce
The LSD1 specific inhibitor INCB059872 enhances the activity of mechanistically distinct immunotherapeutic agents in the syngeneic 4T1 mouse mammary tumor model
MOLECULAR CANCER THERAPEUTICS
IF5.5
2018-01-010
PRE
Lee, Sang Hyun; Diamond, Melody; Chadderton, Antony; Condamine, Thomas; Liu, Huiqing; Roman, Valerie; Lu, Jin; Zhang, Yan; Soloviev, Maxim; He, Chunhong; Wu, Liangxing; Koblish, Holly; Burn, Timothy; Combs, Andrew; Yeleswaram, Swamy; Roberts, Alan; Yao, Wenqing; Hollis, Gregory; Huber, Reid; Scherle, Peggy; Ruggeri, Bruce
Selective inhibition of FGFR4 by INCB062079 is efficacious in models of FGF19-and FGFR4-dependent cancers
CANCER RESEARCH
IF16.6
2017-07-013
PRE
Liu, Phillip C. C.; Lu, Liang; Bowman, Kevin; Stubbs, Matthew C.; Wu, Liangxing; DiMatteo, Darlise; Condon, Sindy; Klabe, Ronald; Qian, Ding-Quan; Wen, Xiaoming; Collier, Paul; Gallagher, Karen; Hansbury, Michael; He, Xin; Ruggeri, Bruce; Yang, Yan-ou; Covington, Maryanne; Burn, Timothy C.; Diamond-Fosbenner, Sharon; Wynn, Richard; Huber, Reid; Yao, Wenqing; Yeleswaram, Swamy; Scherle, Peggy; Hollis, Gregory
Combination of epigenetic regulation via LSD1 inhibition with signal transduction inhibitors significantly enhances anti-tumor activity in models of hematologic malignancies
CANCER RESEARCH
IF16.6
2017-07-012
PRE
Lee, Sang Hyun; Stubbs, Matthew; Juvekar, Ashish; Diamond, Melody; Chadderton, Antony; Collins, Robert; Wen, Xiaoming; Koblish, Holly; He, Chunhong; Wu, Liangxing; Wynn, Richard; Combs, Andrew; Xue, Chu-Biao; Yao, Wenqing; Hollis, Gregory; Huber, Reid; Scherle, Peggy; Ruggeri, Bruce
The LSD1 inhibitor INCB059872 is synergistic with ATRA in models of non-APL acute myelogenous leukemia
CANCER RESEARCH
IF16.6
2016-07-155
PRE
Ye, Min; Liu, Mike; Lu, Jin; Lo, Yvonne; Favata, Margaret; Yang, Gengjie; Diamond, Melody; Dostalik, Valerie; Waeltz, Paul; Fischer, Melissa Ann; He, Chunhong; Wu, Liangxing; Shan, Xiaochuan; Chang, Hong; Covington, Maryanne; Li, Yanlong; Burn, Tim; Wynn, Richard; Yao, Wenqing; Hollis, Gregory; Huber, Reid; Scherle, Peggy; Savona, Michael; Carroll, Martin; Ruggeri, Bruce; Lee, Sang Hyun

研究方向

暂未获取到该数据
W
Wenqing Yao
H 指数:31论文数:138被引数:3,582
P
Peggy Scherle
H 指数:56论文数:386被引数:1.6万
G
Gregory Hollis
H 指数:44论文数:218被引数:8,333
R
Reid Huber
H 指数:28论文数:184被引数:5,394
C
Chunhong He
H 指数:12论文数:74被引数:883
B
Bruce Ruggeri
H 指数:49论文数:210被引数:9,602
M
Melody Diamond
H 指数:13论文数:65被引数:1,415
S
Sang‐Hyun Lee
H 指数:32论文数:187被引数:3,807
S
Swamy Yeleswaram
H 指数:34论文数:189被引数:4,102
R
Richard Wynn
H 指数:54论文数:239被引数:1.0万