Juan J. Pérez - Publications, H-index & Citations

Juan J. Pérez

universitat politècnica de catalunya-barcelona tech

38H指数

307论文数

5.0K被引数

收录论文 71

发表时间

Functional analysis of two novel retinitis pigmentosa mutations reveals structural role of the third transmembrane helix in rhodopsin photoactivation 两种新型色素性视网膜炎突变的功能分析揭示了视杆细胞视蛋白光激活过程中第三跨膜螺旋的结构作用

International Journal of Biological Macromolecules

IF8.5

2026-04-24

OAAI

Pol Fernandez-Gonzalez; Alejandro Cruz; Feifei Wang; Arnau Cordomi; Margarita Morillo; Juan J. Perez; Pere Garriga

Small Molecule Protease Inhibitors as Model Peptidomimetics 小分子蛋白酶抑制剂作为模型肽模拟物

Pharmaceuticals 2025, Vol. 18, Page 1377

IF4.8

2025-09-21

OAAI

Patricia Gomez-Gutierrez; Juan J. Perez

Retigabine increases the conformational stability of the visual photoreceptor rhodopsin

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-11-01

OAAI

Wang, Feifei; Fernandez-Gonzalez, Pol; Jesus Perez, Juan; Morillo, Margarita; Garriga, Pere

The Discovery of inhibitors of the SARS-CoV-2 S protein through computational drug repurposing

COMPUTERS IN BIOLOGY AND MEDICINE

IF6.3

2024-03-01

OAAI

Aviles-Alia, Ana Isabel; Zulaica, Joao; Perez, Juan J.; -Martinez, Jaime Rubio; Geller, Ron; Granadino-Roldan, Jose M.

Assessment of the bound conformation of bombesin to the BB1 and BB2 receptors 评价蛙皮素与BB1和BB2受体的结合构象

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-01-01

OAAI

Vila-Julia, Guillem; Rubio-Martinez, Jaime; Perez, Juan J.

Discovery of Hit Compounds Targeting the P4 Allosteric Site of K-RAS, Identified through Ensemble-Based Virtual Screening 通过基于集合的虚拟筛选发现靶向k-ras的P4变构位点的命中化合物

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2023-10-12

OAAI

Gomez-Gutierrez, Patricia; Rubio-Martinez, Jaime; Perez, Juan J.

A Step Forward toward Selective Activation/Inhibition of Bak, a Pro-Apoptotic Member of the Bcl-2 Protein Family: Discovery of New Prospective Allosteric Sites Using Molecular Dynamics 朝着选择性激活/抑制Bak迈出的一步，Bak是Bcl-2蛋白家族的促凋亡成员: 使用分子动力学发现新的前瞻性变构位点

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2023-05-25

OAAI

Vila-Julia, Guillem; Perez, Juan J.; Rubio-Martinez, Jaime

Peptidic Scaffolds Enable Rapid and Multivariate Secondary Sphere Evolution for an Abiotic Metallocatalyst

INORGANIC CHEMISTRY

IF4.7

2022-04-21

OAAI

Ghosh, Sabari; Phuong Nguyen Tran; McElheny, Dan; Perez, Juan J.; Nguyen, Andy, I

Structure-Activity Studies of Novel Di-substituted [1,2,5]oxadiazolo [3,4-b]pyrazine Analogs Targeting the A-loop Regulatory Site of p38 MAP Kinase

CURRENT MEDICINAL CHEMISTRY

IF3.5

2022-03-01

OAAI

Carrasco, Esther; Gomez-Gutierrez, Patricia; Campos, Pedro M.; Vega, Miguel; Messeguer, Angel; Jesus Perez, Juan

New insights into the molecular mechanism of rhodopsin retinitis pigmentosa from the biochemical and functional characterization of G90V, Y102H and I307N mutations

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2022-01-07

OAAI

Guadalupe Herrera-Hernandez, Maria; Razzaghi, Neda; Fernandez-Gonzalez, Pol; Bosch-Presegue, Laia; Vila-Julia, Guillem; Perez, Juan Jesus; Garriga, Pere

Discovery of Diverse Natural Products as Inhibitors of SARS-CoV-2 Mpro Protease through Virtual Screening 通过虚拟筛选发现多种天然产物作为SARS-CoV-2 Mpro蛋白酶的抑制剂

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2021-11-22

OAAI

Rubio-Martinez, Jaime; Jimenez-Alesanco, Ana; Ceballos-Laita, Laura; Ortega-Alarcon, David; Vega, Sonia; Calvo, Cristina; Benitez, Cristina; Abian, Olga; Velazquez-Campoy, Adrian; Thomson, Timothy M.; Manuel Granadino-Roldan, Jose; Gomez-Gutierrez, Patricia; Perez, Juan J.

Discovery of novel 2,3,5-trisubstituted pyridine analogs as potent inhibitors of IL-1β via modulation of the p38 MAPK signaling pathway

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-11-01

OAAI

Carrasco, Esther; Gomez-Gutierrez, Patricia; Campos, Pedro M.; Vega, Miguel; Messeguer, Angel; Perez, Juan J.

Exploiting Knowledge on Structure-Activity Relationships for Designing Peptidomimetics of Endogenous Peptides 利用结构-活性关系的知识来设计内源肽的肽模拟物

BIOMEDICINES

IF3.9

2021-06-07

OAAI

Perez, Juan J.

Topical application of an amygdalin analogue reduces inflammation and keratinocyte proliferation in a psoriasis mouse model 苦杏仁苷类似物的局部应用可减少牛皮癣小鼠模型中的炎症和角质形成细胞增殖

EXPERIMENTAL DERMATOLOGY

IF3.1

2021-05-28

OAAI

Gago-Lopez, Nuria; Lagunas Arnal, Carmen; Perez, Juan J.; Wagner, Erwin F.

Computational Modeling as a Tool to Investigate PPI: From Drug Design to Tissue Engineering

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2021-05-20

OAAI

Perez, Juan J.; Perez, Roman A.; Perez, Alberto

Effect of Sodium Valproate on the Conformational Stability of the Visual G Protein-Coupled Receptor Rhodopsin

MOLECULES

IF4.6

2021-05-19

OAAI

Razzaghi, Neda; Fernandez-Gonzalez, Pol; Mas-Sanchez, Aina; Vila-Julia, Guillem; Jesus Perez, Juan; Garriga, Pere

Anti-inflammatory effect of amygdalin analogs following topical administration on the TPA-induced irritant contact dermatitis model in mice

EXPERIMENTAL DERMATOLOGY

IF3.1

2021-01-26

OAAI

Porras, Monica; Gomez, Lluis A.; Perez, Juan J.

Molecular Features of Non-Selective Small Molecule Antagonists of the Bradykinin Receptors

PHARMACEUTICALS

IF4.8

2020-09-21

OAAI

Rasaeifar, Bahareh; Gomez-Gutierrez, Patricia; Perez, Juan J.

Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide

SCIENTIFIC REPORTS

IF3.9

2020-09-02

OAAI

Gomara, Maria J.; Perez, Yolanda; Gomez-Gutierrez, Patricia; Herrera, Carolina; Ziprin, Paul; Martinez, Javier P.; Meyerhans, Andreas; Perez, Juan J.; Haro, Isabel

New Insights into the Stereochemical Requirements of the Bombesin BB1 Receptor Antagonists Binding

PHARMACEUTICALS

IF4.8

2020-08-17

OAAI

Rasaeifar, Bahareh; Gomez-Gutierrez, Patricia; Perez, Juan J.

研究方向