Nicole E. Wheeler - Publications, H-index & Citations

Nicole E. Wheeler

international gene synthesis consortium

24H指数

94论文数

2.2K被引数

收录论文 23

发表时间

The limits of sequence-based biosecurity screening tools in the age of AI-assisted protein design 基于序列的生物安全筛选工具在AI辅助蛋白质设计时代的局限性

Frontiers in Bioengineering and Biotechnology

IF4.8

2026-07-26

OAAI

BJ Bruce J. Wittmann; NE Nicole E. Wheeler † ‡; ST Steven T. Murphy ‡; TM Tom Mitchell ‡; BR Brittany Rife Magalis ‡; BT Bryan T. Gemler ‡; KF Kevin Flyangolts ‡; JD James Diggans ‡; AC Adam Clore ‡; JB Jacob Beal ‡; CB Craig Bartling ‡; TA Tessa Alexanian ‡; EH Eric Horvitz

Large-scale testing of antimicrobial lethality at single-cell resolution predicts mycobacterial infection outcomes 单细胞分辨率下的大规模抗菌致死性测试可预测分枝杆菌感染结局

Nature Microbiology

IF19.4

2026-01-09

OAAI

Alexander Jovanovic; Frederick K. Bright; Ahmad Sadeghi; Basil Wicki; Santiago E. Caño Muñiz; Greta C. Giannini; Sara Toprak; Loïc Sauteur; Anna Rodoni; Andreas Wüst; Andréanne Lupien; Sonia Borrell; Dorothy M. Grogono; Nicole E. Wheeler; Philippe Dehio; Johannes Nemeth; Hans Pargger; Rachel Thomson; Scott C. Bell; Sebastien Gagneux; Josephine M. Bryant; Tingying Peng; Andreas H. Diacon; R. Andres Floto; Michael Abanto; Lucas Boeck

Inter-tool Analysis of a NIST Dataset for Assessing Baseline Nucleic Acid Sequence Screening NIST数据集在评估基础核酸序列筛查中的跨工具分析

Applied Biosafety

IF0.7

2025-12-01

PREAI

Laird, Tyler S.; Flyangolts, Kevin; Bartling, Craig; Gemler, Bryan T.; Beal, Jacob; Mitchell, Tom; Murphy, Steven T.; Berlips, Jens; Foner, Leonard; Doughty, Ryan; Quintana, Felix; Nute, Michael; Treangen, Todd J.; Godbold, Gene; Ternus, Krista; Alexanian, Tessa; Wheeler, Nicole; Forry, Samuel P.

Biased sampling driven by bacterial population structure confounds machine learning prediction of antimicrobial resistance 由细菌种群结构驱动的有偏采样干扰了抗菌药物耐药性的机器学习预测

PLOS BIOLOGY

IF7.2

2025-12-01

PREAI

Yu, Yanying; Wheeler, Nicole E.; Barquist, Lars

Strengthening nucleic acid biosecurity screening against generative protein design tools 加强针对生成式蛋白质设计工具的核酸生物安全筛查

Science

IF45.8

2025-10-02

PREAI

Bruce J. Wittmann; Tessa Alexanian; Craig Bartling; Jacob Beal; Adam Clore; James Diggans; Kevin Flyangolts; Bryan T. Gemler; Tom Mitchell; Steven T. Murphy; Nicole E. Wheeler; Eric Horvitz

Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks 生物技术中的负责任人工智能：平衡发现、创新与生物安全风险

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

IF4.8

2025-02-05

OAAI

Wheeler, Nicole E.

Gauge your phage: benchmarking of bacteriophage identification tools in metagenomic sequencing data

MICROBIOME

IF12.7

2023-04-21

OAAI

Ho, Siu Fung Stanley; Wheeler, Nicole E.; Millard, Andrew D.; van Schaik, Willem

River adjustments, geomorphic sensitivity and management implications in the Waipa over line catchment, Aotearoa New Zealand

GEOMORPHOLOGY

IF3.3

2022-08-01

PREAI

Wheeler, Nicole; Pingram, Michael; David, Bruno; Marson, Will; Tunnicliffe, Jon; Brierley, Gary

Rapid Genomic Characterization and Global Surveillance of Klebsiella Using Pathogenwatch

CLINICAL INFECTIOUS DISEASES

IF7.3

2021-12-01

OAAI

Argimon, Silvia; David, Sophia; Underwood, Anthony; Abrudan, Monica; Wheeler, Nicole E.; Kekre, Mihir; Abudahab, Khalil; Yeats, Corin A.; Goater, Richard; Taylor, Ben; Harste, Harry; Muddyman, Dawn; Feil, Edward J.; Brisse, Sylvain; Holt, Kathryn; Donado-Godoy, Pilar; Ravikumar, K. L.; Okeke, Iruka N.; Carlos, Celia; Aanensen, David M.

Whole-genome sequencing as part of national and international surveillance programmes for antimicrobial resistance: a roadmap

BMJ GLOBAL HEALTH

IF6.1

2020-11-25

OAAI

Vegyari, Carotin; Underwood, Anthony; Kekre, Mihir; Argimon, Silvia; Muddyman, Dawn; Abrudan, Monica; Carlos, Celia; Donado-Godoy, Pilar; Okeke, Iruka N.; Ravikumar, K. L.; Abudahab, Khalil; Afolayan, Ayorinde; Arevalo, Alejandra; Bernal-Morales, Johan; Castro, Erik Christopher; Gayeta, June; Govindan, Vandan; Guerrero, Maria Fernanda; Harste, Harry; Herrera, Elmer; Ajiboye, Jolaade Janet; Valdenarro, Polle Krystle; Lagrada, Marietta; Masim, Melissa Ana; Molloy, Ali; Nagaraj, Geeta; Oaikhena, Anderson Osemahu; Olorosa, Agnettah; Prabhu, Akshata; Shammana, Varun; Shincy, M. R.; Sravani, Darmavaram; Stelling, John; Taylor, Ben; Wheeler, Nicole; Schmider, Anneke; Aanensen, David

Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae

NATURE COMMUNICATIONS

IF15.7

2020-10-23

OAAI

Ma, Kevin C.; Mortimer, Tatum D.; Duckett, Marissa A.; Hicks, Allison L.; Wheeler, Nicole E.; Sanchez-Buso, Leonor; Grad, Yonatan H.

Improved Prediction of Bacterial Genotype-Phenotype Associations Using Interpretable Pangenome-Spanning Regressions

MBIO

IF4.7

2020-08-25

OAAI

Lees, John A.; Mai, T. Tien; Galardini, Marco; Wheeler, Nicole E.; Horsfield, Samuel T.; Parkhill, Julian; Corander, Jukka

Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae

NATURE COMMUNICATIONS

IF15.7

2020-08-17

OAAI

Ma, Kevin C.; Mortimer, Tatum D.; Hicks, Allison L.; Wheeler, Nicole E.; Sanchez-Buso, Leonor; Golparian, Daniel; Taiaroa, George; Rubin, Daniel H. F.; Wang, Yi; Williamson, Deborah A.; Unemo, Magnus; Harris, Simon R.; Grad, Yonatan H.

Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation

PLOS GENETICS

IF3.7

2020-06-08

OAAI

Bawn, Matt; Alikhan, Nabil-Fareed; Thilliez, Gaetan; Kirkwood, Mark; Wheeler, Nicole E.; Petrovska, Liljana; Dallman, Timothy J.; Adriaenssens, Evelien M.; Hall, Neil; Kingsley, Robert A.

Lean, mean, learning machines 精益，平均，学习机器

NATURE REVIEWS MICROBIOLOGY

IF103.3

2020-03-19

OAAI

Wheeler, Nicole E.; Sanchez-Buso, Leonor; Argimon, Silvia; Jeffrey, Benjamin

An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation

NATURE COMMUNICATIONS

IF15.7

2019-09-19

OAAI

Van Puyvelde, Sandra; Pickard, Derek; Vandelannoote, Koen; Heinz, Eva; Barbe, Barbara; de Block, Tessa; Clare, Simon; Coomber, Eve L.; Harcourt, Katherine; Sridhar, Sushmita; Lees, Emily A.; Wheeler, Nicole E.; Klemm, Elizabeth J.; Kuijpers, Laura; Kalonji, Lisette Mbuyi; Phoba, Marie-France; Falay, Dadi; Ngbonda, Dauly; Lunguya, Octavie; Jacobs, Jan; Dougan, Gordon; Deborggraeve, Stijn

We are falling behind on TB elimination targets: can whole-genome sequencing guide our efforts?

THORAX

IF7.7

2019-07-22

OAAI

Wheeler, Nicole

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis 人类和病原体基因组的联合测序揭示了肺炎球菌脑膜炎的遗传学

NATURE COMMUNICATIONS

IF15.7

2019-05-15

OAAI

Lees, John A.; Ferwerda, Bart; Kremer, Philip H. C.; Wheeler, Nicole E.; Seron, Mercedes Valls; Croucher, Nicholas J.; Gladstone, Rebecca A.; Bootsma, Hester J.; Rots, Nynke Y.; Wijmega-Monsuur, Alienke J.; Sanders, Elisabeth A. M.; Trzcinski, Krzysztof; Wyllie, Anne L.; Zwinderman, Aeilko H.; van den Berg, Leonard H.; van Rheenen, Wouter; Veldink, Jan H.; Harboe, Zitta B.; Lundbo, Lene F.; de Groot, Lisette C. P. G. M.; van Schoor, Natasja M.; van der Velde, Nathalie; Angquist, Lars H.; Sorensen, Thorkild I. A.; Nohr, Ellen A.; Mentzer, Alexander J.; Mills, Tara C.; Knight, Julian C.; du Plessis, Mignon; Nzenze, Susan; Weiser, Jeffrey N.; Parkhill, Julian; Madhi, Shabir; Benfield, Thomas; von Gottberg, Anne; van der Ende, Arie; Brouwer, Matthijs C.; Barrett, Jeffrey C.; Bentley, Stephen D.; van de Beek, Diederik

Tracing outbreaks with machine learning 用机器学习追踪爆发

NATURE REVIEWS MICROBIOLOGY

IF103.3

2019-02-11

OAAI

Wheeler, Nicole E.

Genomic correlates of extraintestinal infection are linked with changes in cell morphology in Campylobacter jejuni

MICROBIAL GENOMICS

IF4

2019-02-01

OAAI

Wheeler, Nicole E.; Blackmore, Timothy; Reynods, Angela D.; Midwinter, Anne C.; Marshall, Jonathan; French, Nigel P.; Savoian, Matthew S.; Gardner, Paul P.; Biggs, Patrick J.

研究方向