David J. Clarke - Publications, H-index & Citations

David J. Clarke

University of Edinburgh

36H指数

148论文数

3.7K被引数

收录论文 60

发表时间

Isotope Decluttering Reduces Spectral Complexity while Maintaining Protein Structure 同位素消减可降低谱图复杂性同时保持蛋白质结构

Analytical Chemistry

IF6.7

2026-05-29

PREAI

Sneha S. Hakke; Willem E. M. Noteborn; Birol Cabukusta; Ye Gao; Kèvin Knoops; Carmen López-Iglesias; David P. A. Kilgour; David J. Clarke; Anjusha Mathew; Ron M.A Heeren

Shaping Antimalarials: A Geometry-First Approach to PfCLK3 Covalent Inhibitors

Journal of Medicinal Chemistry

IF6.8

2026-01-31

OAAI

Skye B. Brettell; Carla Fuentes-Guerra Bustos; Saumya Sharma; Gillian Cann; Lauren V. Carruthers; Abbey Begen; Graeme Milligan; David J. Clarke; Andrew B. Tobin; Andrew G. Jamieson

Lysine targeting covalent inhibitors of malarial kinase PfCLK3 赖氨酸靶向的恶性疟原虫激酶PfCLK3共价抑制剂

RSC Med. Chem.

IF3.6

2025-08-14

OAAI

Skye B. Brettell; Gillian Cann; Abbey Begen; Saumya Sharma; Amit Mahindra; Lauren V. Carruthers; Graeme Milligan; David J. Clarke; Andrew B. Tobin; Andrew G. Jamieson

Repurposing a Fully Reducing Polyketide Synthase toward 2-Methyl Guerbet-like Lipids

ACS CATALYSIS

IF13.1

2024-10-31

OAAI

Herrera, Michael A.; McColm, Stephen; Craigie, Louise-Marie; Simpson, Joanna; Brown, Fraser; Clarke, David J.; Carr, Reuben; Campopiano, Dominic J.

Modulators of the Hop-HSP90 Protein-Protein Interaction Disrupt KSHV Lytic Replication

ACS INFECTIOUS DISEASES

IF3.8

2024-10-30

OAAI

Okpara, Michael O.; Vaaltyn, Michaelone C.; Watson, Jessica L.; Alhassan, Mahama; Albericio, Fernando; de la Torre, Beatriz G.; Clarke, David J.; Veale, Clinton G. L.; Edkins, Adrienne L.

Targeting PfCLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-10-23

OAAI

Brettell, Skye B.; Janha, Omar; Begen, Abbey; Cann, Gillian; Sharma, Saumya; Olaniyan, Niniola; Yelland, Tamas; Hole, Alison J.; Alam, Benazir; Mayville, Emily; Gillespie, Ross; Capper, Michael; Fidock, David A.; Milligan, Graeme; Clarke, David J.; Tobin, Andrew B.; Jamieson, Andrew G.

Mass spectrometry-based methods for characterizing transient protein-protein interactions

TRENDS IN CHEMISTRY

IF13.6

2024-07-01

PREAI

Veale, Clinton G. L.; Clarke, David J.

Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-01-04

OAAI

Chen, Aochiu; Re, Rebecca N.; Davis, Tony D.; Tran, Kelley; Moriuchi, Yuta W.; Wu, Sitong; La Clair, James J.; Louie, Gordon V.; Bowman, Marianne E.; Clarke, David J.; Mackay, C. Logan; Campopiano, Dominic J.; Noel, Joseph P.; Burkart, Michael D.

Utilising Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) to track the oxidation of lignin by an alkaliphilic laccase

ANALYST

IF3.3

2024-01-01

OAAI

Towle, Zak; Cruickshank, Faye; Mackay, C. Logan; Clarke, David J.; Horsfall, Louise E.

A native mass spectrometry approach to qualitatively elucidate interfacial epitopes of transient protein-protein interactions

CHEMICAL COMMUNICATIONS

IF4.2

2024-01-01

OAAI

Veale, Clinton G. L.; Chakraborty, Abir; Mhlanga, Richwell; Albericio, Fernando; de la Torre, Beatriz G.; Edkins, Adrienne L.; Clarke, David J.

Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates

SCIENCE ADVANCES

IF12.5

2023-11-17

OAAI

Saleeb, Rebecca S.; Leighton, Craig; Lee, Ji-Eun; O'Shaughnessy, Judi; Jeacock, Kiani; Chappard, Alexandre; Cumberland, Robyn; Zhao, Tianxiao; Ball, Sarah R.; Sunde, Margaret; Clarke, David J.; Piche, Kristin; McPhail, Jacob A.; Louwrier, Ariel; Angers, Rachel; Gandhi, Sonia; Downey, Patrick; Kunath, Tilo; Horrocks, Mathew H.

3'-O-ß-Glucosyl-4',5'-didehydro-5'-deoxyadenosine Is a Natural Product of the Nucleocidin Producers Streptomyces virens and Streptomyces calvus

JOURNAL OF NATURAL PRODUCTS

IF3.6

2023-09-25

OAAI

Feng, Xuan; Zhang, Qingzhi; Clarke, David J.; Deng, Hai; O'Hagan, David

Determining the Location of the ?-Synuclein Dimer Interface Using Native Top-Down Fragmentation and Isotope Depletion-Mass Spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

IF2.7

2023-03-28

OAAI

Jeacock, Kiani; Chappard, Alexandre; Gallagher, Kelly J.; Mackay, C. Logan; Kilgour, David P. A.; Horrocks, Mathew H.; Kunath, Tilo; Clarke, David J.

Design and Fabrication of a Fully-Integrated, Miniaturised Fluidic System for the Analysis of Enzyme Kinetics

MICROMACHINES

IF3

2023-02-25

OAAI

Tsiamis, Andreas; Buchoux, Anthony; Mahon, Stephen T.; Walton, Anthony J.; Smith, Stewart; Clarke, David J.; Stokes, Adam A.

A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro

SCIENTIFIC REPORTS

IF3.9

2023-02-08

OAAI

Shelley, Jennifer R.; McHugh, Brian J.; Wills, Jimi; Dorin, Julia R.; Weller, Richard; Clarke, David J.; Davidson, Donald J.

A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif

NATURE COMMUNICATIONS

IF15.7

2022-08-26

OAAI

Wang, Shan; Lin, Sixing; Fang, Qing; Gyampoh, Roland; Lu, Zhou; Gao, Yingli; Clarke, David J.; Wu, Kewen; Trembleau, Laurent; Yu, Yi; Kyeremeh, Kwaku; Milne, Bruce F.; Tabudravu, Jioji; Deng, Hai

Probing TDP-43 condensation using an in silico designed aptamer

NATURE COMMUNICATIONS

IF15.7

2022-06-23

OAAI

Zacco, Elsa; Kantelberg, Owen; Milanetti, Edoardo; Armaos, Alexandros; Panei, Francesco Paolo; Gregory, Jenna; Jeacock, Kiani; Clarke, David J.; Chandran, Siddharthan; Ruocco, Giancarlo; Gustincich, Stefano; Horrocks, Mathew H.; Pastore, Annalisa; Tartaglia, Gian Gaetano

Pore dynamics and asymmetric cargo loading in an encapsulin nanocompartment

SCIENCE ADVANCES

IF12.5

2022-01-28

OAAI

Ross, Jennifer; McIver, Zak; Lambert, Thomas; Piergentili, Cecilia; Bird, Jasmine Emma; Gallagher, Kelly J.; Cruickshank, Faye L.; James, Patrick; Zarazua-Arvizu, Efrain; Horsfall, Louise E.; Waldron, Kevin J.; Wilson, Marcus D.; Mackay, C. Logan; Basle, Arnaud; Clarke, David J.; Marles-Wright, Jon

Magnetic braille using ferrofluids

JOURNAL OF PHYSICS D-APPLIED PHYSICS

IF3.2

2021-03-08

OAAI

Fletcher, A. M.; Downs, J. S. P.; Frost, W.; Clarke, D.; O'Grady, K.; Hirohata, A.

A native mass spectrometry platform identifies HOP inhibitors that modulate the HSP90-HOP protein-protein interaction

CHEMICAL COMMUNICATIONS

IF4.2

2021-01-01

OAAI

Veale, Clinton G. L.; Mateos-Jimenez, Maria; Vaaltyn, Michaelone C.; Muller, Ronel; Makhubu, Matodzi P.; Alhassan, Mahama; de la Torre, Beatriz G.; Albericio, Fernando; Mackay, C. Logan; Edkins, Adrienne L.; Clarke, David J.

研究方向