logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
Z

Zhenkun Lou

mayo clinic

67H指数
306论文数
1.4W被引数
收录论文 143
发表时间
logo
Ursodeoxycholic acid enhances cancer radioimmunotherapy by releasing a human-biased FXR-TRIM22-STAT1 immune brake熊去氧胆酸通过释放偏向于人体的FXR-TRIM22-STAT1免疫刹车增强癌症放射免疫疗法
errCell Research
IF25.9
err2026-09-30
err0
PREAI
errXinyan Li; Peicheng Jiang; Huan Yin; Zhenyu Huo; Xin Xu; Somaira Nowsheen; Khaled Aziz; Sufei Zheng; Nan Sun; Bin Chen; Zhenkun Lou; Min Deng
err分享
err收藏
Author Correction: Combination of PARP and KRASG12D inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDAC作者更正：PARP和KRASG12D抑制剂的组合通过利用胰腺癌的脆弱性增强治疗效果
errNature Communications
IF15.7
err2026-04-22
err0
errOAAI
errXin Xu; Xin Chen; Rongli Xu; Zhenyu Huo; Changying Li; Somaira Nowsheen; Khaled Aziz; Fan Yao; Zhenkun Lou; Min Deng
err分享
err收藏
Combination of PARP and KRASG12D inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDACPARP与KRASG12D抑制剂的联合应用通过利用胰腺导管腺癌（PDAC）的脆弱性增强治疗效果。
errNature Communications
IF15.7
err2026-02-24
err0
errOAAI
errXin Xu; Xin Chen; Rongli Xu; Zhenyu Huo; Changying Li; Somaira Nowsheen; Khaled Aziz; Fan Yao; Zhenkun Lou; Min Deng
err分享
err收藏
Increasing the Response of Mismatch Repair Proficient Rectal Cancer to Immunotherapy with Particle Radiation and DNA Damage Response Inhibitors-Preclinical Evidence通过粒子辐射和DNA损伤反应抑制剂提高错配修复功能完整的直肠癌对免疫治疗的反应性——临床前证据
errCancers
IF4.4
err2026-02-19
err0
errOAAI
errSalazar-Vilches, Cristian J.; Ebner, Daniel K.; Kloeber, Jake A.; Dragojevic, Sonja; Singh, Jasvinder; Haddock, Michael; Sharifzadeh, Yasamin; Sherry, Alexander D.; Jethwa, Krishan R.; Hallemeier, Christopher L.; Merrell, Kenneth W.; Mutter, Robert W.; Lou, Zhenkun; Callaghan, Cameron M.
err分享
err收藏
Clinical Evidence on Particle Radiation, DNA Damage Response Inhibitors, and Immunotherapy for Mismatch Repair-Proficient Rectal CancerSalazar-Vilches, C.J.; Ebner, D.K.; Kloeber, J.A.; Dragojevic, S.; Singh, J.; Haddock, M.; Sharifzadeh, Y.; Sherry, A.D.; Jethwa, K.R.; Hallemeier, C.L.; et al. 关于粒子辐射、DNA损伤反应抑制剂和免疫疗法在错配修复能力正常的直肠癌中的临床证据。Cancers 2026, 18, 652. [Google Scholar] [CrossRef] [PubMed]
errCancers
IF4.4
err2026-02-17
err1
errOAAI
errSalazar-Vilches, Cristian J.; Ebner, Daniel K.; Kloeber, Jake A.; Dragojevic, Sonja; Singh, Jasvinder; Haddock, Michael; Sharifzadeh, Yasamin; Sherry, Alexander D.; Jethwa, Krishan R.; Hallemeier, Christopher L.; Merrell, Kenneth; Mutter, Robert W.; Lou, Zhenkun; Callaghan, Cameron M.
err分享
err收藏
GCN5–ERK lactylation–phosphorylation loop amplifies lactate-driven cancer progressionGCN5–ERK 乳酰化–磷酸化环路放大了乳酸驱动的癌症进展
errNature Chemical Biology
IF13.7
err2026-01-13
err0
PREAI
errBingsong Huang; Mingpeng Jin; Gaofeng Cui; Zhe Wang; Feng Wang; Mu Chen; Lei Zhu; Yunxuan Li; Xiaoning Yang; Rui Li; Jinhuan Wu; Linhui Zhai; Yiming He; Jie Yang; Xin Ding; Qianwen Wang; Zhen Xv; Yaobing Ouyang; Jiale Li; Yangbohui Yang; Ke Li; Zhenkun Lou; Georges Mer; Jing Zhang; Yuping Chen; Jian Yuan; Chunlong Zhong
err分享
err收藏
Redox-driven ADAR1 activation promotes Okazaki fragment maturation and DNA replication integrity氧化还原驱动的ADAR1激活促进冈崎片段成熟和DNA复制完整性
errNature Structural & Molecular Biology
IF10.1
err2026-01-08
err0
PREAI
errBin Chen; Guangchao Sun; Jake A. Kloeber; Huaping Xiao; Yaobin Ouyang; Fei Zhao; Ya Li; Shilin Xu; Sonja Dragojevic; Zheming Wu; Shouhai Zhu; Yiqun Han; Ping Yin; Xinyi Tu; Hongran Qin; Xiang Zhou; Kuntian Luo; Kevin L. Peterson; Jinzhou Huang; Taro Hitosugi; Haiming Dai; Min Deng; Robert W. Mutter; Zhenkun Lou
err分享
err收藏
USP29 and SMURF1 orchestrate FSP1-mediated ferroptosis suppression to facilitate chemoresistance in gastric cancerUSP29和SMURF1协调抑制FSP1-mediated铁死亡以促进胃癌的化学抗性
errNature Communications
IF15.7
err2025-12-12
err0
errOAAI
errZheming Wu; Xinyi Tu; Shouhai Zhu; Qi Jiang; Liewei Wang; Kaixiong Tao; Zhenkun Lou; Min Deng; Xiangyu Zeng
err分享
err收藏
Targeting the Intracellular Domain of PD-L1 to Sensitize Tumors to Cytotoxic Therapy
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errTu, Xinyi; Lou, Zhenkun; Dong, Haidong; Mutter, Robert
err分享
err收藏
Correction: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization更正：USP20通过β-catenin稳定化，正向调控肿瘤发生和化疗耐药性。
errCell Death & Differentiation
IF0
err2025-10-27
err0
errOAAI
errChenming Wu; Kuntian Luo; Fei Zhao; Ping Yin; Ying Song; Min Deng; Jinzhou Huang; Yuping Chen; Lei Li; SeungBaek Lee; JungJin Kim; Qin Zhou; Xinyi Tu; Somaira Nowsheen; Qifeng Luo; Xiumei Gao; Zhenkun Lou; Zhongmin Liu; Jian Yuan
err分享
err收藏
PAK1 inhibition synergistically enhances the anti-tumor efficacy of PARP inhibitors in ovarian cancersPAK1抑制协同增强了PARP抑制剂在卵巢癌中的抗肿瘤效果。
errGenes & Diseases
IF9.4
err2025-10-21
err0
errOAAI
errChangying Li; Xinyan Li; Ming Gao; Min Deng; Ye-Xiong Li; Zhenkun Lou
err分享
err收藏
Targeting the ATM-TRMT10A-BRCA1 axis confers synthetic lethality to PARP inhibition in metastatic castration-resistant prostate cancer靶向ATM-TRMT10A-BRCA1轴使PARP抑制在转移性去势抵抗性前列腺癌中产生合成致死效应
errScience Advances
IF12.5
err2025-10-10
err0
PREAI
errYing Yang; Qiang Liu; Xinyan Li; Hua Zhang; Xin Xu; Qi Ma; Somaira Nowsheen; Khaled Aziz; Ye-Xiong Li; Zhenkun Lou; Qiuzi Zhong; Min Deng
err分享
err收藏
KCTD10 is a sensor for co-directional transcription–replication conflictsKCTD10是共向性转录-复制冲突的传感器。
errNature
IF48.5
err2025-10-08
err0
errOAAI
errJake A. Kloeber; Bin Chen; Guangchao Sun; Charles S. King; Zhiquan Wang; Li Wang; Zheming Wu; Shouhai Zhu; Fei Zhao; Hongran Qin; Yaobin Ouyang; Huaping Xiao; Xinyi Tu; Jing Lu; Yanxia Jiang; Kuntian Luo; Ping Yin; Xinyan Wu; Robert W. Mutter; Jinzhou Huang; Zhenkun Lou
err分享
err收藏
PARP inhibitors potentiate proton therapy end-of-range effects by accelerating replication forks and promoting transcription conflictPARP抑制剂通过加速复制叉和促进转录冲突，增强了质子治疗射程末端的效应。
errinternational journal of radiation oncology biology physics
IF0
err2025-08-27
err0
errOAAI
errYiqun Han; Qin Zhou; Anna Dibbs; Bin Chen; Taylor M. Weiskittel; Nicholas B. Remmes; Zheming Wu; Daniel K. Ebner; Jake A. Kloeber; Cameron M. Callaghan; Anne E. Bendel; Trey C. Mullikin; Nadia N. Laack; Meng Xu-Welliver; Zhenkun Lou; Robert W. Mutter
err分享
err收藏
Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancerNSD3在DNA复制应激中的异构体特异性功能赋予了前列腺癌对PARP抑制剂的抗性
errMolecular Cell
IF16.6
err2025-06-26
err0
PREAI
errShouhai Zhu; Huanyao Gao; Dan Jiang; Guijie Guo; Jing Hou; Yiqun Han; Chao Zhang; Xiaoping Hu; Shreya Indulkar; Jake A. Kloeber; Qi Hu; Yanxia Jiang; Xiangyu Zeng; Yaobin Ouyang; Jing Lu; Ping Yin; Kuntian Luo; Jinzhou Huang; Zheming Wu; Bin Chen; Huaping Xiao; Sonja Dragojevic; Hongran Qin; Xiang Zhou; Jian Jin; Xinyi Tu; Liewei Wang; Zhenkun Lou
err分享
err收藏
Linear energy transfer optimized proton therapy for rectal cancer直肠癌症的线性能量传递优化质子疗法
errRADIOTHERAPY AND ONCOLOGY
IF5.3
err2025-06-01
err0
errOAAI
errMa, Jiasen; Dragojevic, Sonja; Remmes, Nicholas B.; Mendelson, Nicole L.; Kloeber, Jake A.; Ebner, Daniel K.; Wu, Zheming; Gunn, Heather J.; Merrell, Kenneth W.; Hallemeier, Christopher L.; Haddock, Michael G.; Jethwa, Krishan R.; Lou, Zhenkun; Mutter, Robert W.; Callaghan, Cameron M.
err分享
err收藏
The interplay between chromatin remodeling and DNA double-strand break repair: Implications for cancer biology and therapeutics染色质重塑与DNA双链断裂修复之间的相互作用: 对癌症生物学和治疗学的影响
errDNA REPAIR
IF2.7
err2025-02-01
err1
errOAAI
errHe, Liujun; Moon, Jaeyoung; Cai, Chenghui; Hao, Yalan; Lee, Hyorin; Kim, Wootae; Zhao, Fei; Lou, Zhenkun
err分享
err收藏
The UFMylation pathway is impaired in Alzheimer's disease
errMOLECULAR NEURODEGENERATION
IF17.5
err2024-12-18
err0
errOAAI
errYan, Tingxiang; Heckman, Michael G.; Craver, Emily C.; Liu, Chia-Chen; Rawlinson, Bailey D.; Wang, Xue; Murray, Melissa E.; Dickson, Dennis W.; Ertekin-Taner, Nilufer; Lou, Zhenkun; Bu, Guojun; Springer, Wolfdieter; Fiesel, Fabienne C.
err分享
err收藏
STK39-mediated amplification of γ-H2A.X promotes homologous recombination and contributes to PARP inhibitor resistanceΓ-h2a.x的STK39-mediated扩增促进同源重组并有助于PARP抑制剂抗性
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-11-26
err0
errOAAI
errXu, Yi; Li, Changying; Yin, Huan; Nowsheen, Somaira; Xu, Xin; Kang, Wenjuan; Liu, Xin; Chen, Lifeng; Lou, Zhenkun; Yi, Junlin; Deng, Min
err分享
err收藏
Parkin deficiency exacerbates particulate matter-induced injury by enhancing airway epithelial necroptosis
errSCIENCE OF THE TOTAL ENVIRONMENT
IF8
err2024-11-01
err2
errOAAI
errLin, Yuting; Quan, Meiyu; Wang, Xibin; Miao, Wanqi; Xu, Haibo; He, Baiqi; Liu, Bin; Zhang, Yanxia; Chen, Yijing; Zhou, Binqian; Xu, Mengying; Dong, Li; Jin, Xuru; Lou, Zhenkun; Zhang, Jin-San; Chen, Chengshui
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
F
Frederick W. Alt
H 指数: 172 · 论文数: 637
G
Gregory J. Gores
H 指数: 164 · 论文数: 1.0K
A
Arlene H. Sharpe
H 指数: 154 · 论文数: 737
W
William S. Harmsen
H 指数: 113 · 论文数: 936
S
Scott H. Kaufmann
H 指数: 111 · 论文数: 959
查看更多