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K

Kazuhiro Irie

kyoto university

42H指数
337论文数
7.3K被引数
收录论文 96
发表时间
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Isolation and characterization of blastmycetin G, a sofa-conformation fixed analog of teleocidin B's, produced by Streptomyces blastmyceticus从链霉菌属blastmyceticus中分离和鉴定出blastmycetin G，一种teleocidin B的沙发构象固定类似物
errBioscience Biotechnology and Biochemistry
IF1.3
err2026-06-01
err0
PREAI
errKajiyama, Shin-ichiro; Yanagita, Ryo C.; Tsukano, Chihiro; Irie, Kazuhiro
err分享
err收藏
Synthesis of Unnatural Aplysiatoxin Analogs with High Affinity for Protein Kinase C合成具有高亲和力的非天然海兔毒素类似物，用于蛋白激酶C
errEuropean Journal of Organic Chemistry
IF2.7
err2025-10-21
err0
errOAAI
errMana Morishita; Kohei Hada; Yusuke Araki; Keisuke Fukaya; Daisuke Urabe; Ryo C. Yanagita; Jumpei Maki; Yusuke Hanaki; Masaki Kita; Kazuhiro Irie; Toshio Nishikawa
err分享
err收藏
3,4-Dihydroquinolizinium Ring, the Core Structure of Quinocidin, as a Cysteine-Selective Electrophile3,4-二氢喹啉咪环，奎诺西丁的核心结构，作为半胱氨酸选择性亲电体
errCHEMPLUSCHEM
IF2.8
err2025-05-22
err0
PREAI
errYu Nakagawa; Yuka Manabe; Wataru Kondo; Tatsuhiko Kondo; Kazuhiro Irie
err分享
err收藏
Identification of the binding site and immunoreactivity of anti-Aβ antibody 11A1: Comparison with the toxic conformation-specific TxCo-1 antibody抗-Aβ抗体11A1的结合位点及免疫反应性鉴定：与毒性构象特异性TxCo-1抗体的比较
errBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
IF2.2
err2025-04-01
err0
PREAI
errFukui, Rara; Hafizal, Uswah; Kageyama, Yusuke; Irie, Yumi; Matsushima, Yuka; Hosoi, Katsuma; Nakayama, Takahisa; Kaneda, Daita; Hashizume, Yoshio; Miki, Kunio; Kita, Akiko; Mukaisho, Ken-ichi; Kushima, Ryoji; Tooyama, Ikuo; Irie, Kazuhiro
err分享
err收藏
Isolation of Allosteric Tryptase Inhibitor from Methanol Extract of Rhubarb and Enhancement of Its Tryptase Inhibitory Activity by Compounds That Were Screened by In Silico Screening
errMOLECULES
IF4.6
err2025-03-17
err0
PREAI
errFujii, Hidetoshi; Ito, Moeno; Nishioka, Kentaro; Nishino, Katsutoshi; Otsuka, Takanao; Irie, Kazuhiro; Tanaka, Takashi; Nagao, Masaya
err分享
err收藏
Teleocidin B-4, a PKC Activator, Upregulates Hypoxia-Inducible Factor 1 (HIF-1) Activity by Promoting the Accumulation of HIF-1α Protein via the PKCα/mTORC Signaling Pathway
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2024-06-06
err2
PREAI
errIseki, Shogo; Ikeda, Hiroaki; Kobayashi, Sayaka; Irie, Kazuhiro; Harada, Hiroshi; Kakeya, Hideaki
err分享
err收藏
Detection of Dietary Chalcone and Flavonoid Metabolites in Mice Using UPLC-MS/MS and Their Modulatory Effects on Amyloid β Aggregation
errJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
IF6.2
err2023-09-13
err1
PREAI
errTaniwa, Kota; Murakami, Kazuma; Sakaguchi, Yoshiki; Izuo, Naotaka; Hanaki, Mizuho; Sampa, Nobuaki; Kume, Toshiaki; Shimizu, Takahiko; Irie, Kazuhiro
err分享
err收藏
Total Synthesis and Structure Revision of (+)-Lancilactone C
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-06-16
err1
PREAI
errKuroiwa, Hidetaka; Suzuki, Soichiro; Irie, Kazuhiro; Tsukano, Chihiro
err分享
err收藏
Enhancement of Inhibitory Activity by Combining Allosteric Inhibitors Putatively Binding to Different Allosteric Sites on Cathepsin K
errMOLECULES
IF4.6
err2023-05-19
err2
errOAAI
errSato, Shun; Yamamoto, Kana; Ito, Moeno; Nishino, Katsutoshi; Otsuka, Takanao; Irie, Kazuhiro; Nagao, Masaya
err分享
err收藏
Synthesis of Stereoisomeric Simplified Analogs of Alotaketals toward the Elucidation of the Structural Requirements of Protein Kinase C Isozyme-Selective Binding
errORGANIC LETTERS
IF5
err2023-01-30
err2
PREAI
errOkuda, Sogen; Tsukano, Chihiro; Irie, Kazuhiro
err分享
err收藏
A simplified analog of debromoaplysiatoxin lacking the B-ring of spiroketal moiety retains protein kinase C-binding and antiproliferative activities
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2022-11-01
err0
errOAAI
errSekido, Tomoki; Yamamoto, Kosuke; Yanagita, Ryo C.; Kawamani, Yasuhiro; Hanaki, Yusuke; Irie, Kazuhiro
err分享
err收藏
Optimization of the Linker Length in the Dimer Model of E22P-Aβ40 Tethered at Position 38
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2022-09-12
err5
PREAI
errChikugo, Ayaka; Irie, Yumi; Tsukano, Chihiro; Uchino, Ayumi; Maki, Takahito; Kume, Toshiaki; Kawase, Taiji; Hirose, Kenji; Kageyama, Yusuke; Tooyama, Ikuo; Irie, Kazuhiro
err分享
err收藏
Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2022-08-05
err4
PREAI
errUchino, Ayumi; Irie, Yumi; Tsukano, Chihiro; Kawase, Taiji; Hirose, Kenji; Kageyama, Yusuke; Tooyama, Ikuo; Yanagita, Ryo C.; Irie, Kazuhiro
err分享
err收藏
Analysis of binding mode of vibsanin A with protein kinase C C1 domains: An experimental and molecular dynamics simulation study
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2022-07-01
err1
errOAAI
errYanagita, Ryo C.; Otani, Mao; Hatanaka, Satoshi; Nishi, Hiroto; Miyake, Shota; Hanaki, Yusuke; Sato, Masashi; Kawanami, Yasuhiro; Irie, Kazuhiro
err分享
err收藏
Synthetic Biology-Based Discovery of Diterpenoid Pyrones from the Genome of Eupenicillium shearii
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2022-01-20
err17
PREAI
errMorishita, Yohei; Tsukada, Kento; Murakami, Kazuma; Irie, Kazuhiro; Asai, Teigo
err分享
err收藏
AI and computational chemistry-accelerated development of an alotaketal analogue with conventional PKC selectivity
errCHEMICAL COMMUNICATIONS
IF4.2
err2022-01-01
err8
PREAI
errMaki, Jumpei; Oshimura, Asami; Tsukano, Chihiro; Yanagita, Ryo C.; Saito, Yutaka; Sakakibara, Yasubumi; Irie, Kazuhiro
err分享
err收藏
Lysine-targeting inhibition of amyloid β oligomerization by a green perilla-derived metastable chalcone in vitro and in vivo
errRSC CHEMICAL BIOLOGY
IF3.1
err2022-01-01
err4
errOAAI
errMurakami, Kazuma; Sakaguchi, Yoshiki; Taniwa, Kota; Izuo, Naotaka; Hanaki, Mizuho; Kawase, Taiji; Hirose, Kenji; Shimizu, Takahiko; Irie, Kazuhiro
err分享
err收藏
The Novel PKC Activator 10-Methyl-Aplog-1 Combined with JQ1 Induced Strong and Synergistic HIV Reactivation with Tolerable Global T Cell Activation
errVIRUSES-BASEL
IF3.5
err2021-10-09
err10
errOAAI
errWashizaki, Ayaka; Murata, Megumi; Seki, Yohei; Kikumori, Masayuki; Tang, Yinpui; Tan, Weikeat; Wardani, Nadita P.; Irie, Kazuhiro; Akari, Hirofumi
err分享
err收藏
Searching for Natural Products That Delay Nucleation Phase and Promote Elongation Phase of Amyloid β42 toward Alzheimer's Disease Therapeutics
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-08-31
err4
PREAI
errMurakami, Kazuma; Horii, Shiori; Hanaki, Mizuho; Irie, Kazuhiro
err分享
err收藏
Characterization of a Conformation-Restricted Amyloid β Peptide and Immunoreactivity of Its Antibody in Human AD brain
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-08-31
err15
errOAAI
errKageyama, Yusuke; Irie, Yumi; Matsushima, Yuka; Segawa, Tatsuya; Bellier, Jean-Pierre; Hidaka, Kumi; Sugiyama, Hiroshi; Kaneda, Daita; Hashizume, Yoshio; Akatsu, Hiroyasu; Miki, Kunio; Kita, Akiko; Walker, Douglas G.; Irie, Kazuhiro; Tooyama, Ikuo
err分享
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研究方向

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合作期刊
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H 指数: 116 · 论文数: 924
W
William H. Gerwick
H 指数: 96 · 论文数: 653
P
Paul A. Wender
H 指数: 94 · 论文数: 603
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