William H. Parsons - Publications, H-index & Citations

William H. Parsons

oberlin college

36H指数

140论文数

5.4K被引数

收录论文 33

发表时间

Hydralazine inhibits cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma 肼苯哒嗪通过抑制半胱胺二氧化酶来治疗子痫前期并使胶质母细胞瘤衰老。

Science Advances

IF12.5

2025-10-15

PREAI

Kyosuke Shishikura; Jiasong Li; Yiming Chen; Nate R. McKnight; Thomas P. Keeley; Katelyn A. Bustin; Eric W. Barr; Snehil R. Chilkamari; Mahaa Ayub; Sun Woo Kim; Zongtao Lin; Ren-Ming Hu; Kelly Hicks; Xie Wang; Donald M. O’Rourke; J. Martin Bollinger; Zev A. Binder; William H. Parsons; Kirill A. Martemyanov; Aimin Liu; Megan L. Matthews

Activity-Based Protein Profiling of RHBDL4 Reveals Proteolysis of the Enzyme and a Distinct Inhibitor Profile

ACS CHEMICAL BIOLOGY

IF3.8

2024-07-23

PREAI

Davies, Cassondra C.; Hu, Ren-Ming; Kamitsuka, Paul J.; Morais, Gabriel N.; de Gonzalez, Regina Stasser; Bustin, Katelyn A.; Matthews, Megan L.; Parsons, William H.

Development of Activity-Based Protein Profiling Assays for the Human Rhomboid Proteases 开发基于活性的人菱形蛋白酶蛋白谱分析

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-01

OAAI

Nguyen, Dat; de Gonzalez, Regina Stasser; Kamitsuka, Paul; Davies, Cassondra; Franowicz, Nicole; Parsons, William

Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-03-02

OAAI

Wang, Xie; Lin, Zongtao; Bustin, Katelyn A.; McKnight, Nate R.; Parsons, William H.; Matthews, Megan L.

Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets

ACS CENTRAL SCIENCE

IF10.4

2021-08-19

OAAI

Lin, Zongtao; Wang, Xie; Bustin, Katelyn A.; Shishikura, Kyosuke; McKnight, Nate R.; He, Lin; Suciu, Radu M.; Hu, Kai; Han, Xian; Ahmadi, Mina; Olson, Erika J.; Parsons, William H.; Matthews, Megan L.

AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice AIG1和ADTRP是小鼠羟基脂肪酸脂肪酸酯 (FAHFAs) 的内源性水解酶

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-05-01

OAAI

Erikci Ertunc, Meric; Kok, Bernard P.; Parsons, William H.; Wang, Justin G.; Tan, Dan; Donaldson, Cynthia J.; Pinto, Antonio F. M.; Vaughan, Joan M.; Ngo, Nhi; Lum, Kenneth M.; Henry, Cassandra L.; Coppola, Aundrea R.; Niphakis, Micah J.; Cravatt, Benjamin F.; Saez, Enrique; Saghatelian, Alan

Role of AIG1 and ADTRP in Endogenous FAHFA Regulation

FASEB JOURNAL

IF4.2

2020-04-17

OAAI

Ertunc, Meric; Kok, Bernard; Parsons, William; Wang, Justin; Tan, Dan; Donaldson, Cynthia; Pinto, Antonio; Vaughan, Joan; Ngo, Nhi; Lum, Kenneth; Henry, Cassandra; Coppola, Aundrea; Niphakis, Micah; Cravatt, Benjamin; Saez, Enrique; Saghatelian, Alan

Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan

NATURE CHEMICAL BIOLOGY

IF13.7

2019-03-25

OAAI

Chen, Alice L.; Lum, Kenneth M.; Lara-Gonzalez, Pablo; Ogasawara, Daisuke; Cognetta, Armand B.; To, Alan; Parsons, William H.; Simon, Gabriel M.; Desai, Arshad; Petrascheck, Michael; Bar-Peled, Liron; Cravatt, Benjamin F.

Identification of personalized active agents in pediatric medulloblastoma through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft neurosphere and monolayer cells

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Qi, Lin; Du, Yuchen; Bae, Goeun; Mari, Mari; Braun, Frank; Lindsay, Holly; Zhang, Huiyuan; Zhao, Sibo; Injac, Sarah; Baxter, Patricia; Su, Jack; Mancini, Michael; Hampton, Oliver; Parsons, William; Chintagumpala, Mural; Stephan, Clifford; Davies, Peter; Li, Xiaonan

Identification of personalized active agents in pediatric gliomas through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft (PDOX) neurosphere and monolayer cells

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Qi, Lin; Du, Yuchen; Kogiso, Mari; Bae, Goeun; Braun, Frank; Lindsay, Holly; Zhang, Huiyuan; Zhao, Sibo; Injac, Sarah; Baxter, Patricia; Su, Jack; Mancini, Michael; Hampton, Oliver; Parsons, William; Chintagumpala, Murali; Stephan, Clifford; Davies, Peter; Li, Xiao-Nan; Li, Xiao-Nan

A calcium-dependent acyltransferase that produces N-acyl phosphatidylethanolamines

NATURE CHEMICAL BIOLOGY

IF13.7

2016-07-11

OAAI

Ogura, Yuji; Parsons, William H.; Kamat, Siddhesh S.; Cravatt, Benjamin F.

AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs

NATURE CHEMICAL BIOLOGY

IF13.7

2016-03-28

OAAI

Parsons, William H.; Kolar, Matthew J.; Kamat, Siddhesh S.; Cognetta, Armand B., III; Hulce, Jonathan J.; Saez, Enrique; Kahn, Barbara B.; Saghatelian, Alan; Cravatt, Benjamin F.

Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-04-15

PREAI

Parsons, William H.; Calvo, Raul R.; Cheung, Wing; Lee, Yu-Kai; Patel, Sharmila; Liu, Jian; Youngman, Mark A.; Dax, Scott L.; Stone, Dennis; Qin, Ning; Hutchinson, Tasha; Lubin, Mary Lou; Zhang, Sui-Po; Finley, Michael; Liu, Yi; Brandt, Michael R.; Flores, Christopher M.; Player, Mark R.

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

NATURE CHEMICAL BIOLOGY

IF13.7

2015-01-12

133

OAAI

Kamat, Siddhesh S.; Camara, Kaddy; Parsons, William H.; Chen, Dong-Hui; Dix, Melissa M.; Bird, Thomas D.; Howell, Amy R.; Cravatt, Benjamin F.

Saxitoxin

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2014-04-25

138

PREAI

Thottumkara, Arun P.; Parsons, William H.; Du Bois, J.

A 18F-Labeled Saxitoxin Derivative for in Vivo PET-MR Imaging of Voltage-Gated Sodium Channel Expression Following Nerve Injury

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2013-11-21

OAAI

Hoehne, Aileen; Behera, Deepak; Parsons, William H.; James, Michelle L.; Shen, Bin; Borgohain, Preeti; Bodapati, Deepika; Prabhakar, Archana; Gambhir, Sanjiv S.; Yeomans, David C.; Biswal, Sandip; Chin, Frederick T.; Du Bois, J.

Maleimide Conjugates of Saxitoxin as Covalent Inhibitors of Voltage-Gated Sodium Channels

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2013-07-15

PREAI

Parsons, William H.; Du Bois, J.

Marked difference in saxitoxin and tetrodoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1.7)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-10-17

OAAI

Walker, James R.; Novick, Paul A.; Parsons, William H.; McGregor, Malcolm; Zablocki, Jeff; Pande, Vijay S.; Du Bois, J.

Design and Optimization of Benzimidazole-Containing Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2010-12-03

PREAI

Parks, Daniel J.; Parsons, William H.; Colburn, Raymond W.; Meegalla, Sanath K.; Ballentine, Shelley K.; Illig, Carl R.; Qin, Ning; Liu, Yi; Hutchinson, Tasha L.; Lubin, Mary Lou; Stone, Dennis J., Jr.; Baker, Judith F.; Schneider, Craig R.; Ma, Jianya; Damiano, Bruce P.; Flores, Christopher M.; Player, Mark R.

Pyrido[2,3-d]pyrimidin-5-ones: A Novel Class of Antiinflammatory Macrophage Colony-Stimulating Factor-1 Receptor Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-02-04

PREAI

Huang, Hui; Hutta, Daniel A.; Rinker, James M.; Hu, Huaping; Parsons, William H.; Schubert, Carsten; DesJarlais, Renee L.; Crysler, Carl S.; Chaikin, Margery A.; Donatelli, Robert R.; Chen, Yanmin; Cheng, Deping; Zhou, Zhao; Yurkow, Edward; Manthey, Carl L.; Player, Mark R.

研究方向