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陈

陈亚东 (Yadong Chen)

China Pharmaceutical University

33H指数
289论文数
4.3K被引数
收录论文 135
发表时间
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Trends and projections in cause-specific mortality among patients with colorectal cancer in the United States, 1999–20401999—2040年美国结直肠癌患者中特异病因死亡率的趋势与预测
errPublic Health Reviews
IF4.1
err2026-08-28
err0
errOAAI
errZH Ziyan He †; YC Yadong Chen †; YH Yuxing Hu †; JL Jiajia Lin; YW Yifan Wang; CD Caiqiu Deng; YC Yue Cong; JL Jiaming Liu; RZ Rui Zhou; YH Yihan He; FH Fangfang Hou; HZ Haibo Zhang
err分享
err收藏
From biologics to small-molecule modulators: the evolving landscape of interleukin-targeted therapeutics从生物制剂到小分子调节剂：白细胞介素靶向治疗领域的演变格局
errDrug Discovery Today
IF7.5
err2026-07-01
err0
PREAI
errZhu, Yiping; He, Qindi; Chen, Yadong; Lu, Tao; Lu, Shuai
err分享
err收藏
A preliminary exploratory clinical study of Xiao-Chai-Hu-Tang co-administered with irinotecan-based chemotherapy in advanced colorectal cancer小柴胡汤联合伊立替康为基础的化疗治疗晚期结直肠癌的初步探索性临床研究
errJournal of Ethnopharmacology
IF5.4
err2026-04-17
err0
PREAI
errJialin Zhou; Jinsong Rao; Ye Yao; Yanjuan Zhu; Wentao Li; Runze Zhou; Yu Cai; Yadong Chen; Shenyuan Deng; Haibo Zhang; Zhongqiu Liu; Lijun Zhu
err分享
err收藏
TAMNet: Triple adaptive multiplexing network for wide-area infrared small target detectionTAMNet：用于广域红外小目标检测的三重自适应多路复用网络
errNeurocomputing
IF6.5
err2026-03-11
err0
PREAI
errRu Wang; Fanglong Wu; Yadong Chen; Peng Cheng
err分享
err收藏
Integrating Medicinal Chemist Expertise with Deep Learning for Automated Molecular Optimization
errJournal of Medicinal Chemistry
IF6.8
err2026-01-30
err0
PREAI
errLi Liang; Xinyi Yang; Boheng Wan; Lingxi Gu; Yan Yang; Wuchen Xie; Xiaowen Dai; Yuan Xu; Xian Wei; Haichun Liu; Tao Lu; Yadong Chen; Yanmin Zhang
err分享
err收藏
CoDrug: A Text-Driven Molecular Virtual Screening and Multiproperty Optimization Framework via Multimodal Language ModelCoDrug: 通过多模式语言模型的文本驱动的分子虚拟筛选和多属性优化框架
errJournal of Chemical Information and Modeling
IF5.3
err2026-01-22
err0
PREAI
errRui Gu; Yingxu Liu; Bingxing Zhu; Li Liang; Haichun Liu; Yanmin Zhang; Yadong Chen
err分享
err收藏
Design, Synthesis, and Biological Evaluation of Novel NIK Inhibitors for the Treatment of Inflammatory Bowel Disease and Sepsis新型NIK抑制剂的 设计、合成及生物活性评价：用于炎症性肠病和败血症的治疗
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-11-14
err0
PREAI
errNanxia Zhang; Shige Shen; Jiachen Yuan; Yue Liu; Aoting Ni; Sijie He; Mengyu Yang; Chunyue Xu; Haichun Liu; Qinghua Hu; Jie Feng; Tao Lu; Yadong Chen
err分享
err收藏
Design and Synthesis of Novel N-(1H-pyrazol-3-yl)pyrimidin-4-amine Aurora/HDAC Dual Inhibitors for Colorectal Cancer Treatment新型N-(1H-吡唑-3-基)嘧啶-4-胺Aurora/HDAC双抑制剂的设计与合成及其在结直肠癌治疗中的应用
errJournal of Medicinal Chemistry
IF6.8
err2025-11-10
err0
PREAI
errHao Cui; Xu Huang; Rui Li; Meng Zong; Shilong Sun; Hongmei Li; Yadong Chen; Tao Lu; Yong Zhu
err分享
err收藏
M3Hep: a multimodal hepatotoxicity prediction model combining mitochondrial toxicity and masking strategyM3Hep：一种结合线粒体毒性和掩码策略的多模态肝毒性预测模型
errTOXICOLOGY MECHANISMS AND METHODS
IF2.7
err2025-11-01
err0
PREAI
errLiu, Yang; Xie, Yu; Wang, Xiao; Liu, Yingxu; Zhang, Simeng; Zheng, Lidan; Ge, Qian; Gu, Lingxi; Zhang, Yanmin; Liu, Jinfeng; Chen, Yadong; Lu, Mengyi; Liu, Haichun
err分享
err收藏
Discovery of Novel MsbA Inhibitors with a Bivalent Molecular Generative Model利用双价分子生成模型发现新型MsbA抑制剂
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-11-01
err0
PREAI
errQiu, Haodi; Wang, Lei; Li, Baiqing; Wu, Song; Chen, Yadong; Ran, Ting; Xia, Jie; Chen, Hongming
err分享
err收藏
Combining IMWG GA and hematopoietic score to optimize the evaluation of dynamic chemotherapy tolerance in multiple myeloma结合IMWG GA和造血评分以优化多发性骨髓瘤动态化疗耐受性的评估
errAnnals of Medicine
IF4.3
err2025-10-14
err0
errOAAI
errYadong Chen; Fenfen He; Yanyu Chen; Zhibin He; Dongxia Wu; Huihua An; Qian Liu; Yongjiang Zheng
err分享
err收藏
Oral bioavailability property prediction based on task similarity transfer learning基于任务相似性迁移学习的口服生物利用度性质预测
errMolecular Diversity
IF3.8
err2025-09-10
err0
PREAI
errChen Zeng; Chengcheng Xu; Yingxu Liu; Yunya Jiang; Lidan Zheng; Yang Liu; Yanmin Zhang; Yadong Chen; Haichun Liu; Rui Gu
err分享
err收藏
Integrating Generative Pretrained Transformer and Genetic Algorithms for Efficient and Diverse Molecular Generation集成生成预训练Transformer和遗传算法以实现高效且多样化的分子生成
errMolecular Informatics
IF3.1
err2025-08-05
err0
PREAI
errChengcheng Xu; Chen Zeng; Xi Yang; Yingxu Liu; Xiangzhen Ning; Lidan Zheng; Yang Liu; Qing Fan; Chao Xu; Haichun Liu; Xian Wei; Yadong Chen; Yanmin Zhang; Rui Gu
err分享
err收藏
Discovery of THB Derivates as Ferroptosis Inhibitors for the Treatment of Acute Kidney Injury by Targeting VDAC靶向VDAC的THB衍生物作为 ferroptosis 抑制剂在急性肾损伤治疗中的发现
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-05-22
err0
PREAI
errPeng, Shengkuan; Zhang, Wenhao; Sun, Qiaoyi; Zhang, Wenqiang; Chen, Yadong; Lv, Zhicheng; Fang, Zhihang; Lu, Tao; Chen, Guo; Jiao, Yu
err分享
err收藏
MGF-GCN: Multimodal interaction Mamba-aided graph convolutional fusion network for semantic segmentation of remote sensing imagesMGF-GCN：基于多模态交互Mamba辅助图卷积融合网络的高分辨率遥感图像语义分割
errINFORMATION FUSION
IF15.5
err2025-05-13
err0
PREAI
errZhao, Yanfeng; Qiu, Linwei; Yang, Zhenjian; Chen, Yadong; Zhang, Yunjie
err分享
err收藏
Discovery of novel spirocyclic derivates as potent androgen receptor antagonists
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-04-01
err0
PREAI
errZhang, Wenqiang; Zhou, Xiaoyu; Zhu, Hao; Fan, Yawen; Chen, Zhuolin; Wang, Chenxiao; Chen, Xingru; Li, Hongmei; Lu, Tao; Wei, Xian; Chen, Yadong; Chen, Caiping; Jiao, Yu
err分享
err收藏
Exploring MERTK inhibitor binding mechanisms: insights from adaptive steered molecular dynamics and free energy calculation探索MERTK抑制剂的结合机制：自适应引导分子动力学和自由能计算的见解
errJOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
IF2.4
err2025-03-08
err0
PREAI
errYanmin Zhang; Yi Hua; Lingxi Gu; Wenhao Ji; Kairan Cui; Haoxuan Luo; Chao Xu; Haichun Liu; Xian Wei; Yadong Chen
err分享
err收藏
MALT1 Inhibitors and Degraders: Strategies for NF-κB-Driven MalignanciesMALT1 抑制剂和降解剂：针对 NF-κB 驱动的恶性疾病的策略
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-02-25
err0
PREAI
errZhang, Ru-Yue; Wang, Zi-Xuan; Zhang, Meng-Yuan; Wang, Yu-Fan; Zhou, Si-Li; Xu, Jia-Lu; Lin, Wen-Xuan; Ji, Tian-Rui; Chen, Ya-Dong; Lu, Tao
err分享
err收藏
Microbial Selenium-Enriched Bacterial Fertilizer: Biofortification Technology to Boost Pea Sprout Quality and Selenium Content
errAGRONOMY-BASEL
IF3.4
err2025-02-09
err0
errOAAI
errWang, Yaqi; Li, Ying; Wu, Yu; Liu, Yang; Chen, Yadong; Zhang, Yanlong; Jia, Xiangqian
err分享
err收藏
Modulating the phosphorylation status of target proteins through bifunctional molecules
errDRUG DISCOVERY TODAY
IF7.5
err2025-02-01
err0
PREAI
errHe, Qindi; Wang, Zhijie; Wang, Rongrong; Lu, Tao; Chen, Yadong; Lu, Shuai
err分享
err收藏

研究方向

原创小分子药物发现基于人工智能的药物分子设计
合作学者
合作期刊
朱勇 封面图
朱勇 (Yong‐Guan Zhu)
H 指数: 159 · 论文数: 1.6K
黄
黄飞 (Fei Huang)
H 指数: 121 · 论文数: 1.4K
T
Tamio Hayashi
H 指数: 117 · 论文数: 959
王慧 封面图
王慧 (Hui Wang)
H 指数: 113 · 论文数: 2.3K
张
张丽 (Li Zhang)
H 指数: 112 · 论文数: 4.1K
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