Debra K. Newman

versiti blood research institute

H指数:43

被引数:5,793

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A functionally distinct HPA-1a-specific alloantibody associated with fetal/neonatal alloimmune thrombocytopenia that activates platelets via FcγRIIa

一种功能上独特的与胎儿/新生儿同种免疫性血小板减少症相关的HPA-1a特异性 alloantibody，其通过FcγRIIa激活血小板

Transfusion

IF2

2026-09-300

OAAI

Transfusing HPA-mismatched platelets to mimic fetomaternal hemorrhage elicits fetal/neonatal alloimmune thrombocytopenia

输注HPA不合的血小板以模拟胎母出血，可引发胎儿/新生儿同种免疫性血小板减少症

Blood

IF23.1

2026-03-130

In pursuit of FNAIT biomarkers: αVβ3 specificity falls short

寻找FNAIT生物标志物：αVβ3特异性不足

Blood

IF23.1

2025-10-300

PRE

Antigen-specific immunotherapy for platelet alloimmune disorders

HUMAN IMMUNOLOGY

IF2.2

2024-11-010

OAAI

Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2022-02-018

Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia

BLOOD ADVANCES

IF7.1

2021-09-179

SLC4A11 function: evidence for H+ (OH-) and NH3-H+ transport

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2020-02-0119

OAAI

Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding

THROMBOSIS AND HAEMOSTASIS

IF4.3

2019-11-2117

OAAI

Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation

BLOOD ADVANCES

IF7.1

2019-04-098

Hemizygosity for the gene encoding glycoprotein Ibβ is not responsible for macrothrombocytopenia and bleeding in patients with 22q11 deletion syndrome

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2019-02-0110

OAAI

Frontline Science: PECAM-1 (CD31) expression in naive and memory, but not acutely activated, CD8+ T cells

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2018-07-3118

OAAI

CRISPR-mediated deletion of the PECAM-1 cytoplasmic domain increases receptor lateral mobility and strengthens endothelial cell junctional integrity

LIFE SCIENCES

IF5.1

2018-01-014

OAAI

The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-12-0129

OAAI

Multifunctional ion transport properties of human SLC4A11: comparison of the SLC4A11-B and SLC4A11-C variants

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2016-11-0134

OAAI

A whole blood model of thrombocytopenia that controls platelet count and hematocrit

ANNALS OF HEMATOLOGY

IF2.4

2016-08-128

OAAI

The adhesion molecule PECAM-1 enhances the TGF-β-mediated inhibition of T cell function

SCIENCE SIGNALING

IF6.6

2016-03-0818

OAAI

Effect of 22q11.2 deletion on bleeding and transfusion utilization in children with congenital heart disease undergoing cardiac surgery

PEDIATRIC RESEARCH

IF3.1

2015-10-2221

Interplay between Disulfide Bonding and N-Glycosylation Defines SLC4 Na+-coupled Transporter Extracellular Topography

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-02-0112

OAAI

Human SLC4A11-C functions as a DIDS-stimulatable H+ (OH-) permeation pathway: partial correction of R109H mutant transport

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2015-01-1540

OAAI

Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo

维持CD31的T细胞免疫调节功能在体外抑制T/B免疫突触的形成并在体内减轻实验性自身免疫性关节炎的发展

JOURNAL OF AUTOIMMUNITY

IF7

2015-01-0118

PREAI

Debra K. Newman

个人简介

教育背景

工作经历

荣誉奖项

研究方向