logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
N

Nicholas D. P. Cosford

sanford burnham prebys medical discovery institute

46H指数
239论文数
6.3K被引数
收录论文 64
发表时间
logo
Synthesis and Characterization of ULK1/2 Kinase Inhibitors That Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung CancerULK1/2激酶抑制剂的合成与表征：抑制自噬并上调主要组织相容性复合体I的表达，用于非小细胞肺癌的治疗
errACS Chemical Biology
IF3.8
err2026-02-12
err0
PREAI
errFabiana Izidro A. L. Layng; Huiyu Ren; Nicole A. Bakas; Dhanya R. Panickar; Lester J. Lambert; Maria Celeridad; Jiaqian Wu; Laurent De Backer; Preeti Chandrachud; Allison S. Limpert; Mitchell Vamos; Apirat Chaikuad; Betsaida B. Verdugo; Patrick M. Hagan; Sonja N. Brun; Lutz Tautz; Stefan Knapp; Reuben J. Shaw; Guy S. Salvesen; Douglas J. Sheffler; Nicholas D. P. Cosford
err分享
err收藏
Erratum to “Spontaneous daily sleep disruptions associated with morphine dependence and withdrawal in rats” [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103766]
errthe journal of pharmacology and experimental therapeutics
IF0
err2026-01-08
err0
PREAI
errHarlie A. McKelvey; Bethany E. Pierce; Jesse M. Lynch; Audrey L. Kim; Kimberly M. Holter; Reto A. Gadient; Douglas J. Sheffler; Gonul Velicelebi; Nicholas D.P. Cosford; Robert W. Gould
err分享
err收藏
Spontaneous Daily Sleep Disruptions Associated with Morphine Dependence and Withdrawal in Rats与吗啡依赖和戒断相关的自发性日常睡眠中断（大鼠）
errThe Journal of Pharmacology and Experimental Therapeutics
IF0
err2025-10-30
err0
PREAI
errHarlie A. McKelvey; Bethany E. Pierce; Jesse M. Lynch; Audrey L. Kim; Kimberly M. Holter; Reto A. Gadient; Douglas J. Sheffler; Gonul Velicelebi; Nicholas D.P. Cosford; Robert W. Gould
err分享
err收藏
Characterizing Sleep Disruptions Associated with Morphine-Dependence and Spontaneous Withdrawal in Rats表征与吗啡依赖及自发戒断相关的睡眠紊乱在 rats
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errMckelvey, Harlie; Lynch, Jesse; Kim, Audrey; Pierce, Bethany E.; Sheffler, Douglas; Cosford, Nicholas; Gadient, Reto; Gould, Robert; Lyerly, John
err分享
err收藏
Novel Metabotropic Glutamate Receptor Subtype 2 (mGlu2) Positive Allosteric Modulator Attenuates Multiple Methamphetamine-Related Behaviors in Rodents新型代谢性谷氨酸受体亚型2 (mGlu2) 正向别构调节剂减弱啮齿动物多种甲基苯丙胺相关行为
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errGould, Robert; Mckelvey, Harlie; Pierce, Bethany E.; Kim, Audrey; Moriarty, Carson; Holter, Kimberly; Sheffler, Douglas; Gadient, Reto; Velicelebi, Gonul; Cosford, Nicholas
err分享
err收藏
Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase
errACS OMEGA
IF4.3
err2025-01-31
err0
errOAAI
errWu, Jiaqian; Baranowski, Marek R.; Aleshin, Alexander E.; Isiorho, Eta A.; Lambert, Lester J.; De Backer, Laurent J. S.; Han, Ye Na; Das, Ranajit; Sheffler, Douglas J.; Bobkov, Andrey A.; Lemberikman, Alexis M.; Keedy, Daniel A.; Cosford, Nicholas D. P.; Tautz, Lutz
err分享
err收藏
Discovery and development of novel ATG13 degrading compounds that inhibit autophagy and treat Non-Small Cell Lung Cancer
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-12-01
err0
PREAI
errHagan, Patrick M.; Emami, Atoosa; Austin, Hilarie; Pass, Ian; Limpert, Allison; Sheffler, Douglas; Cosford, Nicholas
err分享
err收藏
Discovery and characterization of novel fragment binders of the VHR phosphatase as a drug target for cervix cancer
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-12-01
err0
PREAI
errWu, Jiaqian; Baranowski, Marek R.; Cosford, Nicholas D. P.; Tautz, Lutz
err分享
err收藏
Targeting Unc51-like Autophagy Activating Kinase 1 (ULK1) Overcomes Adaptive Drug Resistance in Acute Myelogenous Leukemia
errMOLECULAR CANCER RESEARCH
IF4.7
err2023-02-14
err5
errOAAI
errBhattacharya, Seemana; Piya, Sujan; Ma, Huaxian; Sharma, Priyanka; Zhang, Qi; Baran, Natalia; Ruvolo, Vivian R.; McQueen, Teresa; Davis, R. Eric; Pourebrahim, Rasoul; Konopleva, Marina; Kantarjian, Hagop; Cosford, Nicholas D. P.; Andreeff, Michael; Borthakur, Gautam
err分享
err收藏
Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-01-01
err6
errOAAI
errRaveendra-Panickar, Dhanya; Finlay, Darren; Layng, Fabiana Izidro; Lambert, Lester J.; Celeridad, Maria; Zhao, Ming; Barbosa, Karina; De Backer, Laurent J. S.; Kwong, Elizabeth; Gosalia, Palak; Rodiles, Socorro; Holleran, John; Ardecky, Robert; Grotegut, Stefan; Olson, Steven; Hutchinson, John H.; Pasquale, Elena B.; Vuori, Kristiina; Deshpande, Aniruddha J.; Cosford, Nicholas D. P.; Tautz, Lutz
err分享
err收藏
Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-11-22
err22
errOAAI
errBata, Nicole; Chaikuad, Apirat; Bakas, Nicole A.; Limpert, Allison S.; Lambert, Lester J.; Sheffler, Douglas J.; Berger, Lena M.; Liu, Guoxiong; Yuan, Cunxiang; Wang, Li; Peng, Yi; Dong, Jing; Celeridad, Maria; Layng, Fabiana; Knapp, Stefan; Cosford, Nicholas D. P.
err分享
err收藏
Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-11-17
err37
errOAAI
errRen, Huiyu; Bakas, Nicole A.; Vamos, Mitchell; Chaikuad, Apirat; Limpert, Allison S.; Wimer, Carina D.; Brun, Sonja N.; Lambert, Lester J.; Tautz, Lutz; Celeridad, Maria; Sheffler, Douglas J.; Knapp, Stefan; Shaw, Reuben J.; Cosford, Nicholas D. P.
err分享
err收藏
Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-09-22
err5
errOAAI
errYamasaki, Tomoteru; Zhang, Xiaofei; Kumata, Katsushi; Zhang, Yiding; Deng, Xiaoyun; Fujinaga, Masayuki; Chen, Zhen; Mori, Wakana; Hu, Kuan; Wakizaka, Hidekatsu; Hatori, Akiko; Xie, Lin; Ogawa, Masanao; Nengaki, Nobuki; Van, Richard; Shao, Yihan; Sheffler, Douglas J.; Cosford, Nicholas D. P.; Liang, Steven H.; Zhang, Ming-Rong
err分享
err收藏
Inhibitor of apoptosis protein antagonists as novel targeted chemotherapeutic agents for acute myeloid leukemia
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errFinlay, Darren; Bata, Nicole; Limpert, Allison; Heimann, Dominik; Teriete, Peter; Burian, Carol; Mason, James; Cosford, Nicholas D.; Vuori, Kristiina
err分享
err收藏
How the gatekeeper helix of the thioesterase domain of fatty acid synthase controls substrate recognition and initiation of cleavage of the proper substrate
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errFromm, Joseph; Teriete, Peter; Cieplak, Piotr; Misson, Laetitia; Burkart, Michael; Cosford, Nicholas
err分享
err收藏
Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo
errCELL REPORTS MEDICINE
IF10.6
err2020-06-01
err40
errOAAI
errPache, Lars; Marsden, Matthew D.; Teriete, Peter; Portillo, Alex J.; Heimann, Dominik; Kim, Jocelyn T.; Soliman, Mohamed S. A.; Dimapasoc, Melanie; Carmona, Camille; Celeridad, Maria; Spivak, Adam M.; Planelles, Vicente; Cosford, Nicholas D. P.; Zack, Jerome A.; Chanda, Sumit K.
err分享
err收藏
Preparation of Mono- and Diisocyanates in Flow from Renewable Carboxylic Acids
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2020-05-29
err26
PREAI
errHai, Thien An Phung; De Backer, Laurent J. S.; Cosford, Nicholas D. P.; Burkart, Michael D.
err分享
err收藏
A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors用于表征SHP2 (PTPN11) 磷酸酶抑制剂的细胞靶标接合测定法
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-02-01
err14
errOAAI
errRomero, Celeste; Lambert, Lester J.; Sheffler, Douglas J.; De Backer, Laurent J. S.; Raveendra-Panickar, Dhanya; Celeridad, Maria; Grotegut, Stefan; Rodiles, Socorro; Holleran, John; Sergienko, Eduard; Pasquale, Elena B.; Cosford, Nicholas D. P.; Tautz, Lutz
err分享
err收藏
Synthesis and preliminary studies of 11C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 2
errTHERANOSTICS
IF13.3
err2020-01-01
err14
errOAAI
errZhang, Xiaofei; Zhang, Yiding; Chen, Zhen; Shao, Tuo; Van, Richard; Kumata, Katsushi; Deng, Xiaoyun; Fu, Hualong; Yamasaki, Tomoteru; Rong, Jian; Hu, Kuan; Hatori, Akiko; Xie, Lin; Yu, Qingzhen; Ye, Weijian; Xu, Hao; Sheffler, Douglas J.; Cosford, Nicholas D. P.; Shao, Yihan; Tang, Pingping; Wang, Lu; Zhang, Ming-Rong; Liang, Steven H.
err分享
err收藏
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
errBIOCHEMICAL JOURNAL
IF4.3
err2019-03-12
err44
errOAAI
errChaikuad, Apirat; Koschade, Sebastian E.; Stolz, Alexandra; Zivkovic, Katarina; Pohl, Christian; Shaid, Shabnam; Ren, Huiyu; Lambert, Lester J.; Cosford, Nicholas D. P.; Brandts, Christian H.; Knapp, Stefan
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
H
Hagop M. Kantarjian
H 指数: 230 · 论文数: 5.5K
J
John C. Reed
H 指数: 179 · 论文数: 1.5K
M
Michael Andreeff
H 指数: 139 · 论文数: 2.0K
M
Marina Konopleva
H 指数: 130 · 论文数: 2.1K
G
Guy S. Salvesen
H 指数: 119 · 论文数: 383
查看更多