Nobuhiko Kayagaki - Publications, H-index & Citations

Nobuhiko Kayagaki

Genentech

63H指数

137论文数

2.6W被引数

收录论文 53

发表时间

Gasdermin D-mediated delivery of caspase inhibitors to suppress pyroptosis Gasdermin D介导的半胱天冬酶抑制剂递送以抑制焦亡

Nature

IF48.5

2026-08-03

PREAI

Katarzyna M. Groborz; Melissa E. Truong; Irma Stowe; Katherine E. Wickliffe; Bettina Lee; Stefan Bauernfried; Robert S. Jones; Emile Plise; Elizabeth S. Levy; Ponien Kou; Wyne P. Lee; Juan Zhang; Hanna Budayeva; Christopher M. Rose; Julia Nguyen; Malgorzata Kalinka; Marcin Drag; Nobuhiko Kayagaki; Kim Newton; Marcin Poreba; Vishva M. Dixit

Surveying the roles of NINJ1 in plasma membrane rupture 调查NINJ1在质膜破裂中的作用

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-06-25

PREAI

Ishan Deshpande; Nobuhiko Kayagaki

Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury 作者更正：使用NINJ1抗体抑制膜破裂可限制组织损伤

Nature

IF48.5

2025-11-27

OAAI

Nobuhiko Kayagaki; Irma B. Stowe; Kamela Alegre; Ishan Deshpande; Shuang Wu; Zhonghua Lin; Opher S. Kornfeld; Bettina L. Lee; Juan Zhang; John Liu; Eric Suto; Wyne P. Lee; Kellen Schneider; WeiYu Lin; Dhaya Seshasayee; Tushar Bhangale; Cecile Chalouni; Matthew C. Johnson; Prajakta Joshi; Jan Mossemann; Sarah Zhao; Danish Ali; Neil M. Goldenberg; Blayne A. Sayed; Benjamin E. Steinberg; Kim Newton; Joshua D. Webster; Ryan L. Kelly; Vishva M. Dixit

Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion 致病性细菌逃避ROCK驱动的上皮细胞排出

Nature

IF48.5

2025-10-22

OAAI

Giovanni Luchetti; Marin V. Miner; Rachael M. Peterson; William P. Scott; Praveen Krishnamoorthy; Eric M. Kofoed; Angel G. Jimenez; Hua Zhang; Man Wah Tan; Rohit Reja; Tommy K. Cheung; Elizabeth Skippington; Yuxin Liang; Christopher M. Rose; Nobuhiko Kayagaki; Kim Newton; Isabella Rauch; Vishva M. Dixit

Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView (OCT, 10.1038/s41587-024-02391-0, 2024)基于图像的多路复用混合筛选方法在原代细胞和组织中的应用（PerturbView, OCT, 10.1038/s41587-024-02391-0, 2024）

NATURE BIOTECHNOLOGY

IF41.7

2025-02-26

PREAI

Kudo, Takamasa; Meireles, Ana M.; Moncada, Reuben; Chen, Yushu; Wu, Ping; Gould, Joshua; Hu, Xiaoyu; Kornfeld, Opher; Jesudason, Rajiv; Foo, Conrad; Hockendorf, Burkhard; Corrada Bravo, Hector; Town, Jason P.; Wei, Runmin; Rios, Antonio; Chandrasekar, Vineethkrishna; Heinlein, Melanie; Chuong, Amy S.; Cai, Shuangyi; Lu, Cherry Sakura; Coelho, Paula; Mis, Monika; Celen, Cemre; Kljavin, Noelyn; Jiang, Jian; Richmond, David; Thakore, Pratiksha; Benito-Gutierrez, Elia; Geiger-Schuller, Kathryn; Hleap, Jose Sergio; Kayagaki, Nobuhiko; Melo, Felipe; Mcginnis, Lisa; Li, Bo; Singh, Avtar; Garraway, Levi; Rozenblatt-Rosen, Orit; Regev, Aviv; Lubeck, Eric

Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView 具有扰动视图的原代细胞和组织中基于图像的多路复用合并屏幕

NATURE BIOTECHNOLOGY

IF41.7

2024-10-07

PREAI

Kudo, Takamasa; Meireles, Ana M.; Moncada, Reuben; Chen, Yushu; Wu, Ping; Gould, Joshua; Hu, Xiaoyu; Kornfeld, Opher; Jesudason, Rajiv; Foo, Conrad; Hockendorf, Burkhard; Bravo, Hector Corrada; Town, Jason P.; Wei, Runmin; Rios, Antonio; Chandrasekar, Vineethkrishna; Heinlein, Melanie; Chuong, Amy S.; Cai, Shuangyi; Lu, Cherry Sakura; Coelho, Paula; Mis, Monika; Celen, Cemre; Kljavin, Noelyn; Jiang, Jian; Richmond, David; Thakore, Pratiksha; Benito-Gutierrez, Elia; Geiger-Schuller, Kathryn; Hleap, Jose Sergio; Kayagaki, Nobuhiko; Melo, Felipe; McGinnis, Lisa; Li, Bo; Singh, Avtar; Garraway, Levi; Rozenblatt-Rosen, Orit; Regev, Aviv; Lubeck, Eric

Control of Cell Death in Health and Disease

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE

IF34.5

2024-01-24

OAAI

Kayagaki, Nobuhiko; Webster, Joshua D.; Newton, Kim

Epigenetic and transcriptional control of gasdermins

SEMINARS IN IMMUNOLOGY

IF7.8

2023-11-01

PREAI

Cadena, Cristhian; Kornfeld, Opher S.; Lee, Bettina L.; Kayagaki, Nobuhiko

Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury 用NINJ1抗体抑制膜破裂可限制组织损伤

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2023-05-17

OAAI

Kayagaki, Nobuhiko; Stowe, Irma B.; Alegre, Kamela; Deshpande, Ishan; Wu, Shuang; Lin, Zhonghua; Kornfeld, Opher S.; Lee, Bettina L.; Zhang, Juan; Liu, John; Suto, Eric; Lee, Wyne P.; Schneider, Kellen; Lin, WeiYu; Seshasayee, Dhaya; Bhangale, Tushar; Chalouni, Cecile; Johnson, Matthew C.; Joshi, Prajakta; Mossemann, Jan; Zhao, Sarah; Ali, Danish; Goldenberg, Neil M.; Sayed, Blayne A.; Steinberg, Benjamin E.; Newton, Kim; Webster, Joshua D.; Kelly, Ryan L.; Dixit, Vishva M.

Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections

CELL REPORTS

IF6.9

2021-08-01

OAAI

Digby, Zsofi; Tourlomousis, Panagiotis; Rooney, James; Boyle, Joseph P.; Bibo-Verdugo, Betsaida; Pickering, Robert J.; Webster, Steven J.; Monie, Thomas P.; Hopkins, Lee J.; Kayagaki, Nobuhiko; Salvesen, Guy S.; Warming, Soren; Weinert, Lucy; Bryant, Clare E.

Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-15

OAAI

Davies, Christopher W.; Stowe, Irma; Phung, Qui T.; Ho, Hoangdung; Bakalarski, Corey E.; Gupta, Aaron; Zhang, Yingnan; Lill, Jennie R.; Payandeh, Jian; Kayagaki, Nobuhiko; Koerber, James T.

Rescue from a fiery death: A therapeutic endeavor

SCIENCE

IF45.8

2019-11-08

PREAI

Kayagaki, Nobuhiko; Dixit, Vishva M.

IRF2 transcriptionally induces GSDMD expression for pyroptosis IRF2转录诱导焦亡的GSDMD表达

SCIENCE SIGNALING

IF6.6

2019-05-21

133

PREAI

Kayagaki, Nobuhiko; Lee, Bettina L.; Stowe, Irma B.; Kornfeld, Opher S.; O'Rourke, Karen; Mirrashidi, Kathleen M.; Haley, Benjamin; Watanabe, Colin; Roose-Girma, Merone; Modrusan, Zora; Kummerfeld, Sarah; Reja, Rohit; Zhang, Yafei; Cho, Vicky; Andrews, T. Daniel; Morris, Lucy X.; Goodnow, Christopher C.; Bertram, Edward M.; Dixit, Vishva M.

Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2018-08-22

132

OAAI

Lee, Bettina L.; Stowe, Irma B.; Gupta, Aaron; Kornfeld, Opher S.; Roose-Girma, Merone; Anderson, Keith; Warming, Soren; Zhang, Juan; Lee, Wyne P.; Kayagaki, Nobuhiko

ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages

SCIENTIFIC REPORTS

IF3.9

2018-02-28

117

OAAI

Lee, Bettina L.; Mirrashidi, Kathleen M.; Stowe, Irma B.; Kummerfeld, Sarah K.; Watanabe, Colin; Haley, Benjamin; Cuellar, Trinna L.; Reichelt, Michael; Kayagaki, Nobuhiko

The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

PLOS PATHOGENS

IF4.9

2016-12-02

104

OAAI

Ratner, Dmitry; Orning, M. Pontus A.; Proulx, Megan K.; Wang, Donghai; Gavrilin, Mikhail A.; Wewers, Mark D.; Alnemri, Emad S.; Johnson, Peter F.; Lee, Bettina; Mecsas, Joan; Kayagaki, Nobuhiko; Goguen, Jon D.; Lien, Egil

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes 焦亡期间caspase-11引起的GsdmD p30在膜中形成孔

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-06-23

760

OAAI

Aglietti, Robin A.; Estevez, Alberto; Gupta, Aaron; Ramirez, Monica Gonzalez; Liu, Peter S.; Kayagaki, Nobuhiko; Ciferri, Claudio; Dixit, Vishva M.; Dueber, Erin C.

Caspase-11: arming the guards against bacterial infection

IMMUNOLOGICAL REVIEWS

IF8.3

2015-04-16

PREAI

Stowe, Irma; Lee, Bettina; Kayagaki, Nobuhiko

Interleukin-22 Induces Interleukin-18 Expression from Epithelial Cells during Intestinal Infection

IMMUNITY

IF26.3

2015-02-01

173

OAAI

Munoz, Melba; Eidenschenk, Celine; Ota, Naruhisa; Wong, Kit; Lohmann, Uwe; Kuehl, Anja A.; Wang, Xiaoting; Manzanillo, Paolo; Li, Yun; Rutz, Sascha; Zheng, Yan; Diehl, Lauri; Kayagaki, Nobuhiko; van Lookeren-Campagne, Menno; Liesenfeld, Oliver; Heimesaat, Markus; Ouyang, Wenjun

Phosphorylation-dependent activity of the deubiquitinase DUBA

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2012-01-15

110

PREAI

Huang, Oscar W.; Ma, Xiaolei; Yin, JianPing; Flinders, Jeremy; Maurer, Till; Kayagaki, Nobuhiko; Phung, Qui; Bosanac, Ivan; Arnott, David; Dixit, Vishva M.; Hymowitz, Sarah G.; Starovasnik, Melissa A.; Cochran, Andrea G.

研究方向