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Y

Yajie Yin

Parker Institute for Cancer Immunotherapy
H指数:18
被引数:1,223

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Synthetic transcription factors designed by domain recombination enhance CAR T cell antitumor function

通过结构域重组设计的合成转录因子增强了CAR T细胞抗肿瘤功能

Cell
IF42.5
2026-08-190
OA
Oliver Takacsi-Nagy; Sivakanthan Kasinathan; Austin Hartman; Yajie Yin; Lujing Wu; Andy Y. Chen; Laura M. Moser; Audre P. May; Gabriella C. Reeder; Emily Celallos Fuentes; Courtney Kernick; Johnathan Lu; Alison K. McClellan; Colin J. Raposo; Brendan Terrall; Nicole E. Theberath; Patrick K. Yan; Peng Xu; Elena Sotillo; Justin Eyquem
Engineering T cells with a membrane-tethered version of SLP-76 overcomes antigen-low resistance to CAR T cell therapy

工程化T细胞，通过膜锚定形式的SLP-76可克服CAR T细胞疗法中的抗原低表达耐药性。

Nature Cancer
IF28.5
2025-10-230
OAAI
Maria Caterina Rotiroti; Aidan M. Tousley; Hoyin Chu; Marco Herrera-Barrera; Antigoni Manousopoulou; Won-Ju Kim; Yajie Yin; Thomas Spencer Parish; Aniela Mitchell; Malcolm Holterhus; Lea Wenting Rysavy; Guillermo Nicolas Dalton; Katherine Ann Freitas; Gernot Kaber; Korbinian N. Kropp; Christopher A. Klebanoff; Ansuman T. Satpathy; Leo D. Wang; Caleb A. Lareau; Robbie G. Majzner
Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation

不同的表观基因组景观是组织特异性记忆T细胞分化的基础

IMMUNITY
IF26.3
2024-09-014
PRE
Buquicchio, Frank A.; Fonseca, Raissa; Yan, Patrick K.; Wang, Fangyi; Evrard, Maximilien; Obers, Andreas; Gutierrez, Jacob C.; Raposo, Colin J.; Belk, Julia A.; Daniel, Bence; Zareie, Pirooz; Yost, Kathryn E.; Qi, Yanyan; Yin, Yajie; Nico, Katherine F.; Tierney, Flora M.; Howitt, Michael R.; Lareau, Caleb A.; Satpathy, Ansuman T.; Mackay, Laura K.
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells
NATURE GENETICS
IF31.8
2023-06-2917
OA
Lareau, Caleb A.; Dubois, Sonia M.; Buquicchio, Frank A.; Hsieh, Yu-Hsin; Garg, Kopal; Kautz, Pauline; Nitsch, Lena; Praktiknjo, Samantha D.; Maschmeyer, Patrick; Verboon, Jeffrey M.; Gutierrez, Jacob C.; Yin, Yajie; Fiskin, Evgenij; Luo, Wendy; Mimitou, Eleni P.; Muus, Christoph; Malhotra, Rhea; Parikh, Sumit; Fleming, Mark D.; Oevermann, Lena; Schulte, Johannes; Eckert, Cornelia; Kundaje, Anshul; Smibert, Peter; Vardhana, Santosha A.; Satpathy, Ansuman T.; Regev, Aviv; Sankaran, Vijay G.; Agarwal, Suneet; Ludwig, Leif S.
Co-opting signalling molecules enables logic-gated control of CAR T cells
Nature
IF48.5
2023-03-080
PRE
Aidan M. Tousley; Maria Caterina Rotiroti; Louai Labanieh; Lea Wenting Rysavy; Won-Ju Kim; Caleb Lareau; Elena Sotillo; Evan W. Weber; Skyler P. Rietberg; Guillermo Nicolas Dalton; Yajie Yin; Dorota Klysz; Peng Xu; Eva L. de la Serna; Alexander R. Dunn; Ansuman T. Satpathy; Crystal L. Mackall; Robbie G. Majzner
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations

来自高通量单细胞RNA测序的线粒体变体富集可解决克隆种群

NATURE BIOTECHNOLOGY
IF41.7
2022-02-2461
OA
Miller, Tyler E.; Lareau, Caleb A.; Verga, Julia A.; DePasquale, Erica A. K.; Liu, Vincent; Ssozi, Daniel; Sandor, Katalin; Yin, Yajie; Ludwig, Leif S.; El Farran, Chadi A.; Morgan, Duncan M.; Satpathy, Ansuman T.; Griffin, Gabriel K.; Lane, Andrew A.; Love, J. Christopher; Bernstein, Bradley E.; Sankaran, Vijay G.; van Galen, Peter
Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium

单细胞多组学定义了与胸腺上皮具有独特同源性的致耐受性胸腺外Aire表达群体

SCIENCE IMMUNOLOGY
IF16.3
2021-11-2641
OA
Wang, Jiaxi; Lareau, Caleb A.; Bautista, Jhoanne L.; Gupta, Alexander R.; Sandor, Katalin; Germino, Joe; Yin, Yajie; Arvedson, Matthew P.; Reeder, Gabriella C.; Cramer, Nathan T.; Xie, Fang; Ntranos, Vasilis; Satpathy, Ansuman T.; Anderson, Mark S.; Gardner, James M.
ONC206, an Imipridone Derivative, Induces Cell Death Through Activation of the Integrated Stress Response in Serous Endometrial Cancer In Vitro

Imipridone衍生物ONC206通过体外激活浆液性子宫内膜癌中的整合应激反应诱导细胞死亡

FRONTIERS IN ONCOLOGY
IF3.3
2020-10-2018
OAAI
Zhang, Yingao; Huang, Yu; Yin, Yajie; Fan, Yali; Sun, Wenchuan; Zhao, Xiaoling; Tucker, Katherine; Staley, Allison; Paraghamian, Sarah; Hawkins, Gabrielle; Prabhu, Varun; Allen, Joshua E.; Zhou, Chunxiao; Bae-Jump, Victoria

研究方向

暂未获取到该数据
V
Victoria Bae‐Jump
H 指数:41论文数:483被引数:5,915
C
Chunxiao Zhou
H 指数:34论文数:271被引数:3,655
W
Wenchuan Sun
H 指数:13论文数:66被引数:522
C
Caleb A. Lareau
H 指数:60论文数:285被引数:1.9万
A
Ansuman T. Satpathy
H 指数:75论文数:322被引数:2.8万
Z
Ziwei Fang
H 指数:13论文数:58被引数:6,411
Y
Yali Fan
H 指数:21论文数:113被引数:2,646
K
Katherine L. Tucker
H 指数:0论文数:4被引数:0
A
Allison Staley
H 指数:10论文数:65被引数:389
V
Varun V. Prabhu
H 指数:28论文数:362被引数:2,846