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C

Courtney C. Aldrich

university of minnesota

48H指数
370论文数
6.6K被引数
收录论文 228
发表时间
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Design; Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosis设计；哌嗪基生物A抑制剂的合成与生物评价：靶向结核分枝杆菌生物素生物合成
errJournal of Medicinal Chemistry
IF6.8
err2026-04-22
err0
PREAI
errQiang Liu; Curtis A. Engelhart; Joshua B. Wallach; Peng Ge; Tsung-Yun Wong; Moyosore O. Orimoloye; Suyapa Rodriguez; Yahani P. Jayasinghe; Donald R. Ronning; Véronique Dartois; Jansy P. Sarathy; Dirk Schnappinger; Matthew D. Zimmerman; Courtney C. Aldrich
err分享
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Metal–Ligand Interactions: Overlooked Confounders in Antibiotic Discovery and Development金属-配体相互作用：抗生素发现与发展中被忽视的混杂因素
errACS Infectious Diseases
IF3.8
err2026-03-11
err0
PREAI
errZiyi Jia; Moyosore Oluseyi Orimoloye; Courtney C. Aldrich; Anthony D. Baughn
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Development of activators for SERCA2a for heart failure treatmentsSERCA2a激活剂的研发用于心力衰竭治疗
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-11-29
err0
PREAI
errMarzena Brinkmann; Tsung-Yun (Kent) Wong; Osha Roopnarine; Samantha L. Yuen; Kaja Berg; Razvan L. Cornea; Robyn T. Rebbeck; David D. Thomas; Courtney C. Aldrich
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Large-scale high-throughput screen for cardiac ryanodine receptor targeted therapeutics大规模高通量筛选针对心脏ryanodine受体靶向治疗药物
errJournal of Biological Chemistry
IF3.9
err2025-11-17
err0
errOAAI
errRoman Nikolaienko; Elisa Bovo; Jonathan C. Solberg; Marzena A. Brinkmann; Levy M. Treinen; Andrew R. Thompson; Kaja C.G. Berg; David D. Thomas; Jennifer J. Thomas; Donald M. Bers; Courtney C. Aldrich; Aleksey V. Zima; Razvan L. Cornea; Robyn T. Rebbeck
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Kupyaphores─Self-Assembling Diisocyanolipopeptide ZnII Ionophores in Mycobacterium tuberculosis ZnII/CuI/II Homeostasis and Antibacterial EffectsKupyaphores─在结核分枝杆菌ZnII/CuI/II稳态和抗菌效应中的自组装二异氰酸脂肽锌离子载体
errJournal of the American Chemical Society
IF15.6
err2025-10-23
err0
PREAI
errTsung-Yun Wong; Sachin Sharma; Kritee Mehdiratta; Rashmi S. Bhosale; Kaavya Nimmakayala; Randall K. Wilharm; Arnab Chakraborty; Moyosore Orimoloye; Qiang Liu; Siddhesh S. Kamat; Valérie C. Pierre; Rajesh S. Gokhale; Courtney C. Aldrich
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Mechanism of the dual action self-potentiating antitubercular drug morphazinamide双作用自增强抗结核药物morphazinamide的作用机制
errPNAS NEXUS
IF3.8
err2025-08-01
err1
errOAAI
errOstrer, Lev; Crooks, Taylor A.; Howe, Michael D.; Vo, Sang; Jia, Ziyi; Hegde, Pooja; Schacht, Nathan; Aldrich, Courtney C.; Baughn, Anthony D.
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Structure-Activity Relationship of Pseudouridimycin Focusing on the Improvement of Chemical Stability
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-07-01
err0
PREAI
errOkawa, Ryotaro; Artsimovitch, Irina; Katsuyama, Akira; Sato, Toyotaka; Aldrich, Courtney C.; Ichikawa, Satoshi
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Enzymatic Pathway for Kupyaphore Degradation in Mycobacterium tuberculosis: Mechanism of Metal Homeostasis and Turnover结核分枝杆菌中kuphyaphore降解的酶促途径：金属稳态和周转的机制
errACS Chemical Biology
IF3.8
err2025-06-30
err0
PREAI
errRashmi S. Bhosale; Arnab Chakraborty; Tsung-Yun Wong; Dattatraya P. Masal; Rahul Choudhury; Sonali Srivastava; D. Srinivasa Reddy; Courtney C. Aldrich; Siddhesh S. Kamat; Debasisa Mohanty; Rajesh S. Gokhale
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Mycobactin and clofazimine activity are negatively correlated in mycobacteriaMycobactin和clofazimine活性在分枝杆菌中呈负相关。
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2025-04-03
err0
errOAAI
errVoskuil, Martin I.; Covey, Christopher R.; Reichlen, Matthew J.; Chatterjee, Anushila; Duerkop, Breck A.; Dawadi, Surendra; Aldrich, Courtney C.; Aaring, Alexander
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err收藏
Central nervous system distributional kinetics of selected histone deacetylase inhibitors
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-01-01
err1
errOAAI
errZhang, Wenqiu; Oh, Ju-Hee; Zhang, Wenjuan; Aldrich, Courtney C.; Sirianni, Rachael W.; Elmquist, William F.
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Protecting Group Control of Hydroxyketone-Hemiketal Tautomeric Equilibrium Enables the Stereoselective Synthesis of a 1′-Azido C-Nucleoside
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2024-11-19
err0
PREAI
errPanda, Subhankar; Orimoloye, Moyosore O.; Poudel, Tej Narayan; De Jonghe, Steven; Jochmans, Dirk; Neyts, Johan; Aldrich, Courtney C.
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Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin
errNATURE COMMUNICATIONS
IF15.7
err2024-05-16
err0
errOAAI
errQu, Di; Ge, Peng; Botella, Laure; Park, Sae Woong; Lee, Ha-Na; Thornton, Natalie; Bean, James M.; Krieger, Inna V.; Sacchettini, James C.; Ehrt, Sabine; Aldrich, Courtney C.; Schnappinger, Dirk
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Pharmacokinetics of Panobinostat: Interspecies Difference in Metabolic Stability
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2024-04-01
err0
errOAAI
errZhang, Wenqiu; Oh, Ju-Hee; Zhang, Wenjuan; Aldrich, Courtney C.; Sirianni, Rachael W.; Elmquist, William F.
err分享
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Amycolatopsis mediterranei: A Sixty-Year Journey from Strain Isolation to Unlocking Its Potential of Rifamycin Analogue Production by Combinatorial Biosynthesis
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2024-01-30
err1
PREAI
errSood, Utkarsh; Mueller, Moritz; Lan, Tian; Garg, Gauri; Singhvi, Nirjara; Hira, Princy; Singh, Priya; Nigam, Aeshna; Verma, Mansi; Lata, Pushp; Kaur, Hardeep; Kumar, Abhilash; Rawat, Charu Dogra; Lal, Sukanya; Aldrich, Courtney; Bechthold, Andreas; Lal, Rup
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Blocking ADP-ribosylation expands the anti-mycobacterial spectrum of rifamycins
errMICROBIOLOGY SPECTRUM
IF3.8
err2023-10-17
err2
errOAAI
errGanapathy, Uday S.; Lan, Tian; Dartois, Veronique; Aldrich, Courtney C.; Dick, Thomas
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ADP-ribosylation-resistant rifabutin analogs show improved bactericidal activity against drug-tolerant M. abscessus in caseum surrogate
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-09-19
err8
errOAAI
errXie, Min; Ganapathy, Uday S.; Lan, Tian; Osiecki, Paulina; Sarathy, Jansy P.; Dartois, Veronique; Aldrich, Courtney C.; Dick, Thomas
err分享
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Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators
errSCIENTIFIC REPORTS
IF3.9
err2023-07-01
err10
errOAAI
errRoopnarine, Osha; Yuen, Samantha L.; Thompson, Andrew R.; Roelike, Lauren N.; Rebbeck, Robyn T.; Bidwell, Philip A.; Aldrich, Courtney C.; Cornea, Razvan L.; Thomas, David D.
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Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis
errMBIO
IF4.7
err2023-06-23
err7
errOAAI
errSharma, Ritu; Hartman, Travis E.; Beites, Tiago; Kim, Jee-Hyun; Eoh, Hyungjin; Engelhart, Curtis A.; Zhu, Linnan; Wilson, Daniel J.; Aldrich, Courtney C.; Ehrt, Sabine; Rhee, Kyu Young; Schnappinger, Dirk
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Gram Scale Synthesis of Membrane-Active Antibacterial 4-Quinolone Lead Compound
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2023-04-18
err2
errOAAI
errJachak, Gorakhnath R.; Orimoloye, Moyosore O.; Aldrich, Courtney C.
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SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naph- thoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-03-01
err2
errOAAI
errBerg, Kaja; Hegde, Pooja; Pujari, Venugopal; Brinkmann, Marzena; Wilkins, David Z.; Parish, Tanya; Crick, Dean C.; Aldrich, Courtney C.
err分享
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研究方向

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合作学者
合作期刊
D
David L. Kaplan
H 指数: 194 · 论文数: 2.4K
J
John R. Yates
H 指数: 188 · 论文数: 1.5K
P
Prashant V. Kamat
H 指数: 155 · 论文数: 1.1K
刘彬 封面图
刘彬 (Bin Liu)
H 指数: 142 · 论文数: 1.7K
C
Carolyn R. Bertozzi
H 指数: 140 · 论文数: 942
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