logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
C

Chunquan Sheng

second military medical university (naval medical university)

56H指数
333论文数
1.1W被引数
收录论文 189
发表时间
logo
Discovery of Novel Hsp90 Inhibitor-Evodiamine Derivative Conjugates as Potent and Orally Active Antitumor Agents for Colon Cancer Therapy新型Hsp90抑制剂-吴茱萸碱衍生物共轭物作为结肠癌治疗中具有显著疗效和口服活性的抗肿瘤剂
errJournal of Medicinal Chemistry
IF6.8
err2026-05-28
err0
PREAI
errYuhang Sun; Keliang Li; Hua Sun; Changlu Li; Jie Su; Yuhong Shang; Liangsiyu Zhang; Yutong Zhu; Haoyu Li; Chunquan Sheng; Shanchao Wu
err分享
err收藏
Exosome-Coated Boron-Containing Evodiamine Derivative Triggered by Pathology-Specific Reactive Oxygen Species Targets Myofibroblasts to Ameliorate Hypertrophic Scarring外泌体包被的硼元素含有的吴茱萸碱衍生物，通过病理特异性活性氧触发，靶向肌成纤维细胞以改善增生性瘢痕
errACS Applied Materials & Interfaces
IF0
err2026-05-19
err0
PREAI
errFuting Shu; Hongchao Huang; Hua Sun; Ziyu Fang; Wenfeng Wu; Zixuan Zhou; Chunquan Sheng; Huazhen Liu; Shichu Xiao; Shanchao Wu; Yongjun Zheng
err分享
err收藏
Discovery of New Pyrazolone Derivatives for Treating Invasive Fungal Infections by Iron Homeostasis Disruption通过铁稳态破坏发现用于治疗侵袭性真菌感染的新型吡唑酮衍生物
errJournal of Medicinal Chemistry
IF6.8
err2026-05-04
err0
PREAI
errPiaopiao Zou; Jie Tu; Ruxiong Liu; Qianqian He; Wanzhen Yang; Yahui Huang; Chunquan Sheng
err分享
err收藏
Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for Improving Muscle Function and Alleviating Fatigue烟酰胺磷酸核糖基转移酶（NAMPT）激活剂的发现：用于改善肌肉功能并缓解疲劳
errJournal of Medicinal Chemistry
IF6.8
err2026-04-16
err0
PREAI
errYanjie Li; Sicheng Yang; Yuxin Fang; Yu Li; Zhewei Xia; Chunquan Sheng; Guoqiang Dong; Jing Zhang
err分享
err收藏
Discovery of Benzodiazepinepyrimidine Scaffold Derivatives as Potent Doublecortin-Like Kinase 1 (DCLK1) Inhibitors for the Treatment of Acute Inflammatory Diseases双苯二氮䓬嘧啶骨架衍生物作为强效双皮层素样激酶1（DCLK1）抑制剂在急性炎症性疾病治疗中的发现
errJournal of Medicinal Chemistry
IF6.8
err2025-10-07
err0
PREAI
errShanchao Wu; Lei Wang; Yingqi Song; Changlu Li; Xiaoyao Lu; Qingwei Bu; Keliang Li; Yuping Chen; Hua Sun; Guang Liang; Gaozhi Chen; Chunquan Sheng
err分享
err收藏
HerTACs Enable Tumor-Selective Lysosomal Degradation of Membrane and Extracellular Proteins via HER2 TraffickingHerTACs 通过 HER2 转运实现肿瘤选择性溶酶体降解膜蛋白和细胞外蛋白
errAngewandte Chemie International Edition
IF0
err2025-08-21
err0
PREAI
errShipeng He; Wenjing Huang; Yaojin Zhu; Fei Gao; Yuxin Fang; Jiayi Zhu; Yuhan Bao; Guoqiang Dong; Prof. Chunquan Sheng
err分享
err收藏
Chemical and genetic molecular glues to degrade CoREST corepressors化学和遗传分子胶水降解CoREST核心抑制因子
errActa Pharmaceutica Sinica B
IF14.6
err2025-07-07
err0
errOAAI
errYing-Qi Song; Qingjun Li; Chunquan Sheng
err分享
err收藏
Discovery of Potent PDEδ/NAMPT Dual Inhibitors: Preclinical Evaluation in KRAS Mutant Pancreatic Cancer Cells发现强效PDEδ/NAMPT双靶点抑制剂：在KRAS突变胰腺癌细胞中的临床前评估
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-04-28
err0
PREAI
errZhu, Yaojin; Chen, Zhenqian; Wu, Guoyuan; Fang, Yuxin; Bao, Yuhan; Zhu, Jiayi; Dong, Guoqiang; Sheng, Chunquan
err分享
err收藏
Discovery of New Pyrazolone Carbothioamide Derivatives as Potent Antifungal Agents for the Treatment of Candidiasis and Cryptococcosis新型吡唑酮硫代甲酰胺衍生物作为强效抗真菌剂，用于治疗念珠菌病和隐球菌病
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-04-04
err1
PREAI
errLiang, Tingting; Tu, Jie; He, Qianqian; Zou, Piaopiao; Yang, Wanzhen; Huang, Yahui; Liu, Na; Sheng, Chunquan
err分享
err收藏
Evodiamine-Based Nitroreductase Responsive Theranostic Agents for Treatment of Colon Cancer埃vodiamine基硝基还原酶响应性诊疗一体化剂在结肠癌治疗中的应用
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-04-02
err0
PREAI
errLi, Keliang; Sun, Yuhang; Ma, Zonglin; Chen, Yuping; Li, Xinglin; Dong, Guoqiang; Liu, Dan; Sheng, Chunquan
err分享
err收藏
Strategies for Precise Modulation of Protein Degradation蛋白质降解精确调控的策略
errACCOUNTS OF CHEMICAL RESEARCH
IF17.7
err2025-03-25
err0
PREAI
errHe, SP; Dong, GQ; Sheng, CQ
err分享
err收藏
[18F]QTFT, a nicotinate-based radiotracer targeting P2Y12 with satisfactory blood-brain barrier (BBB) permeability[18F]QTFT，一种基于烟酸的放射性示踪剂，靶向P2Y12，具有令人满意的血脑屏障（BBB）通透性。
errACTA PHARMACEUTICA SINICA B
IF14.6
err2025-02-01
err0
errOAAI
errSong, YQ; Sheng, CQ
err分享
err收藏
Discovery of new fungal jumonji H3K27 demethylase inhibitors for the treatment of Cryptococcus neoformans and Candida auris infections
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-01-01
err0
PREAI
errLiu, Xin; Li, Wang; Liu, Yang; Wang, Xiaoqing; Shi, Qiao; Yang, Wanzhen; Tu, Jie; Wang, Yan; Sheng, Chunquan; Liu, Na
err分享
err收藏
Precise HER2 Protein Degradation via Peptide-Conjugated Photodynamic Therapy for Enhanced Breast Cancer Immunotherapy通过肽缀合的光动力疗法进行精确的HER2蛋白降解，以增强乳腺癌免疫疗法
errADVANCED SCIENCE
IF14.1
err2024-11-18
err0
errOAAI
errGuo, Changyong; Gao, Fei; Wu, Guoyuan; Li, Jinqiu; Sheng, Chunquan; He, Shipeng; Hu, Honggang
err分享
err收藏
Indolo[3,2-c]isoquinoline Hydroxamic Acid Derivatives as Novel Orally Topoisomerase-Histone Deacetylase Dual Inhibitors for NSCLC Therapy
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-10-23
err0
PREAI
errWang, Bichuan; Shi, Ting; Jia, Shuolei; Wang, Enyuan; Ruan, Xiuqin; Sheng, Chunquan; Wu, Shanchao; Zhou, Qingfa
err分享
err收藏
Discovery of Janus Kinase and Histone Deacetylase Dual Inhibitors as a New Strategy to Treat Psoriasis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-10-17
err0
PREAI
errHu, Weijie; Shen, Jing; Zhou, Chenchen; Tai, Zongguang; Zhu, Quangang; Chen, Zhongjian; Huang, Yahui; Sheng, Chunquan
err分享
err收藏
RMC-7977, a highly selective inhibitor of the active RAS-GTP to treat pancreatic cancer高选择性活性RAS-GTP抑制剂RMC-7977治疗胰腺癌
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-10-01
err0
errOAAI
errSong, Ying-Qi; Li, Qingjun; Sheng, Chunquan
err分享
err收藏
Targeting EFHD2 inhibits interferon-γ signaling and ameliorates non-alcoholic steatohepatitis
errJOURNAL OF HEPATOLOGY
IF33
err2024-09-01
err3
PREAI
errFu, Jiang-Tao; Liu, Jian; Wu, Wen-Bin; Chen, Yi-Ting; Lu, Guo-Dong; Cao, Qi; Meng, Hong-Bo; Tong, Jie; Zhu, Jia-Hui; Wang, Xu-Jie; Liu, Yi; Zhuang, Chunlin; Sheng, Chunquan; Shen, Fu-Ming; Liu, Xingguang; Wang, Hua; Yu, Yongsheng; Zhang, Yuefan; Liang, Hai-Yan; Zhang, Jia-Bao; Li, Dong-Jie; Li, Xiang; Wang, Zhi-Bin; Wang, Pei
err分享
err收藏
PROTAC derivatization of natural products for target identification and drug discovery: Design of evodiamine-based PROTACs as novel REXO4 degraders天然产物的PROTAC衍生化用于靶标鉴定和药物发现: 基于evodiamine的PROTAC作为新型REXO4降解剂的设计
errJOURNAL OF ADVANCED RESEARCH
IF13
err2024-09-01
err4
errOAAI
errChen, Shuqiang; Bi, Kaijian; Liang, Huixin; Wu, Zhe; Huang, Min; Chen, Xi; Dong, Guoqiang; Sheng, Chunquan
err分享
err收藏
Hydrophobic tagging-induced degradation of NAMPT in leukemia cells
errCHINESE CHEMICAL LETTERS
IF8.9
err2024-09-01
err1
PREAI
errGuo, Menglu; Song, Ying-Qi; Cheng, Junfei; Dong, Guoqiang; Sun, Xun; Sheng, Chunquan
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
余君 封面图
余君 (Jun Yu)
H 指数: 133 · 论文数: 1.8K
K
Kanyi Pu
H 指数: 131 · 论文数: 389
王
王华 (Hua Wang)
H 指数: 113 · 论文数: 1.6K
张建 封面图
张建 (Jian Zhang)
H 指数: 99 · 论文数: 1.6K
T
Tony D. James
H 指数: 98 · 论文数: 846
查看更多