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The Specification and Functional Maturation of Sub-Cerebral Projection Neurons Derived from Human Induced Pluripotent Stem Cells 源自人诱导多能干细胞的下脑投射神经元的功能特化与成熟 Jordan, Zachary; Singh, Anukriti; Kattapong-Graber, Seth; Goswami, Sonal; Sanjana, Neville E.; Zuccaro, Emanuela; Zhang, Feng; Eggan, Kevin; Hsieh, Jenny; Hermann, Brian P.; Hebert, Jean M.; Maroof, Asif Mirza 分享 收藏
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CSMD1 regulates brain complement activity and circuit development Baum, Matthew L.; Wilton, Daniel K.; Fox, Rachel G.; Carey, Alanna; Hsu, Yu-Han H.; Hu, Ruilong; Jantti, Henna J.; Fahey, Jaclyn B.; Muthukumar, Allie K.; Salla, Nikkita; Crotty, William; Scott-Hewitt, Nicole; Bien, Elizabeth; Sabatini, David A.; Lanser, Toby B.; Frouin, Arnaud; Gergits, Frederick; Havik, Bjarte; Gialeli, Chrysostomi; Nacu, Eugene; Lage, Kasper; Blom, Anna M.; Eggan, Kevin; McCarroll, Steven A.; Johnson, Matthew B.; Stevens, Beth 分享 收藏
Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS Limone, Francesco; Mordes, Daniel A.; Couto, Alexander; Joseph, Brian J.; Mitchell, Jana M.; Therrien, Martine; Ghosh, Sulagna Dia; Meyer, Daniel; Zhang, Yingying; Goldman, Melissa; Bortolin, Laura; Cobos, Inma; Stevens, Beth; McCarroll, Steven A.; Kadiu, Irena; Burberry, Aaron; Pietilainen, Olli; Eggan, Kevin 分享 收藏
Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis Huang, Xuan; Lee, Seungkyu; Chen, Kuchuan; Kawaguchi, Riki; Wiskow, Ole; Ghosh, Sulagna; Frost, Devlin; Perrault, Laura; Pandey, Roshan; Klim, Joseph R.; Boivin, Bruno; Hermawan, Crystal; Livak, Kenneth J.; Geschwind, Daniel H.; Wainger, Brian J.; Eggan, Kevin C.; Bean, Bruce P.; Woolf, Clifford J. 分享 收藏
Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice Limone, Francesco; Couto, Alexander; Wang, Jin-Yuan; Zhang, Yingying; Mccourt, Blake; Huang, Cerianne; Minkin, Adina; Jani, Marghi; Mcneer, Sarah; Keaney, James; Gillet, Gaelle; Lopez-Gonzalez, Rodrigo; Goodman, Wendy A.; Kadiu, Irena; Eggan, Kevin; Burberry, Aaron 分享 收藏
High-dimensional phenotyping to define the genetic basis of cellular morphology 高维表型确定细胞形态的遗传基础 Tegtmeyer, Matthew; Arora, Jatin; Asgari, Samira; Cimini, Beth A.; Nadig, Ajay; Peirent, Emily; Liyanage, Dhara; Way, Gregory P.; Weisbart, Erin; Nathan, Aparna; Amariuta, Tiffany; Eggan, Kevin; Haghighi, Marzieh; Mccarroll, Steven A.; O'Connor, Luke; Carpenter, Anne E.; Singh, Shantanu; Nehme, Ralda; Raychaudhuri, Soumya 分享 收藏
Econazole selectively induces cell death in NF1-homozygous mutant tumor cells Lakes, Yenal B.; Moye, Stefanie L.; Mo, Juan; Tegtmeyer, Matthew; Nehme, Ralda; Charlton, Maura; Salinas, Gabrielle; Mckay, Renee M.; Eggan, Kevin; Le, Lu Q. 分享 收藏
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro 将iPSC衍生的人类小胶质细胞暴露于脑底物，可以在体外产生和操纵多种转录状态 Dolan, Michael-John; Therrien, Martine; Jereb, Sasa; Kamath, Tushar; Gazestani, Vahid; Atkeson, Trevor; Marsh, Samuel E. E.; Goeva, Aleksandrina; Lojek, Neal M. M.; Murphy, Sarah; White, Cassandra M. M.; Joung, Julia; Liu, Bingxu; Limone, Francesco; Eggan, Kevin; Hacohen, Nir; Bernstein, Bradley E. E.; Glass, Christopher K. K.; Leinonen, Ville; Blurton-Jones, Mathew; Zhang, Feng; Epstein, Charles B. B.; Macosko, Evan Z. Z.; Stevens, Beth 分享 收藏
Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality Biniszkiewicz, D; Gribnau, J; Ramsahoye, B; Gaudet, F; Eggan, K; Humpherys, D; Mastrangelo, MA; Jun, Z; Walter, J; Jaenisch, R 分享 收藏
Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages Wells, Michael F.; Nemesh, James; Ghosh, Sulagna; Mitchell, Jana M.; Salick, Max R.; Mello, Curtis J.; Meyer, Daniel; Pietilainen, Olli; Piccioni, Federica; Guss, Ellen J.; Raghunathan, Kavya; Tegtmeyer, Matthew; Hawes, Derek; Neumann, Anna; Worringer, Kathleen A.; Ho, Daniel; Kommineni, Sravya; Chan, Karrie; Peterson, Brant K.; Raymond, Joseph J.; Gold, John T.; Siekmann, Marco T.; Zuccaro, Emanuela; Nehme, Ralda; Kaykas, Ajamete; Eggan, Kevin; McCarroll, Steven A. 分享 收藏
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders 人类诱导神经元中的蛋白质相互作用研究表明自闭症谱系障碍的趋同生物学 Pintacuda, Greta; Hsu, Yu-Han H.; Tsafou, Kalliopi; Li, Ka Wan; Martin, Jacqueline M.; Riseman, Jackson; Biagini, Julia C.; Ching, Joshua K. T.; Mena, Daya; Gonzalez-Lozano, Miguel A.; Egri, Shawn B.; Jaffe, Jake; Smit, August B.; Fornelos, Nadine; Eggan, Kevin C.; Lage, Kasper 分享 收藏
Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons Pietilainen, Olli; Trehan, Aditi; Meyer, Daniel; Mitchell, Jana; Tegtmeyer, Matthew; Valakh, Vera; Gebre, Hilena; Chen, Theresa; Vartiainen, Emilia; Farhi, Samouil L.; Eggan, Kevin; McCarroll, Steven A.; Nehme, Ralda 分享 收藏
Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues Limone, Francesco; San Juan, Irune Guerra; Mitchell, Jana M.; Smith, Janell L. M.; Raghunathan, Kavya; Meyer, Daniel; Ghosh, Sulagna Dia; Couto, Alexander; Klim, Joseph R.; Joseph, Brian J.; Gold, John; Mello, Curtis J.; Nemesh, James; Smith, Brittany M.; Verhage, Matthijs; McCarroll, Steven A.; Pietilainen, Olli; Nehme, Ralda; Eggan, Kevin 分享 收藏
A Multimodal and Multifunctional CMOS Cellular Interfacing Array for Digital Physiology and Pathology Featuring an Ultra Dense Pixel Array and Reconfigurable Sampling Rate Wang, Adam Y.; Sheng, Yuguo; Li, Wanlu; Jung, Doohwan; Junek, Gregory V.; Liu, Hangxing; Park, Jongseok; Lee, Dongwon; Wang, Mian; Maharjan, Sushila; Kumashi, Sagar; Hao, Jin; Zhang, Yu S.; Eggan, Kevin; Wang, Hua 分享 收藏
Loss of mouse Stmn2 function causes motor neuropathy (vol 110, pg 1671, 2022) Juan, Irune Guerra San; Nash, Leslie A.; Smith, Kevin S.; Leyton-Jaimes, Marcel F.; Qian, Menglu; Klim, Joseph R.; Limone, Francesco; Dorr, Alexander B.; Couto, Alexander; Pintacuda, Greta; Joseph, Brian J.; Whisenant, D. Eric; Noble, Caroline; Melnik, Veronika; Potter, Deirdre; Holmes, Amie; Burberry, Aaron; Verhage, Matthijs; Eggan, Kevin 分享 收藏
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