Yossef Av‐Gay - Publications, H-index & Citations

Yossef Av‐Gay

university of toronto

54H指数

153论文数

9.4K被引数

收录论文 59

发表时间

Comparative Phenotypic Screening Identifies Protein Synthesis Inhibitors as Compounds That Enhance Early Acidification of Mycobacterium tuberculosis in Macrophages 比较表型筛选鉴定出蛋白质合成抑制剂作为增强巨噬细胞中结核分枝杆菌早期酸化的化合物

ACS Infectious Diseases

IF3.8

2026-07-01

PREAI

Leah Rankine-Wilson; Yossef Av-Gay

Acidic pH modulates Burkholderia cenocepacia antimicrobial susceptibility in the cystic fibrosis nutritional environment 酸性pH调节囊性纤维化营养环境中的伯克霍尔德菌抗生素敏感性

MICROBIOLOGY SPECTRUM

IF3.8

2023-12-12

OAAI

Morales, L. Daniela; Av-Gay, Yossef; Murphy, Michael E. P.

Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication

MOLECULAR BIOMEDICINE

IF10.1

2022-12-12

OAAI

Shapira, Tirosh; Vimalanathan, Selvarani; Rens, Celine; Pichler, Virginia; Pena-Diaz, Sandra; Jordana, Grace; Rees, William; Winkler, Dirk F. H.; Sarai, Iqbal; Steiner, Theodore; Jean, Francois; Pelech, Steven; Av-Gay, Yossef

Hit Compounds and Associated Targets in Intracellular Mycobacterium tuberculosis

MOLECULES

IF4.6

2022-07-12

OAAI

Tsui, Clement K. M.; Sorrentino, Flavia; Narula, Gagandeep; Mendoza-Losana, Alfonso; Gonzalez del Rio, Ruben; Perez Herran, Esther; Lopez, Abraham; Bojang, Adama; Zheng, Xingji; Jesus Remuinan-Blanco, Modesto; Av-Gay, Yossef

Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1

CELL CHEMICAL BIOLOGY

IF7.2

2022-05-01

OAAI

Persaud, Rosanne; Li, Sheena C.; Chao, Joseph D.; Forestieri, Roberto; Donohue, Elizabeth; Balgi, Aruna D.; Zheng, Xingji; Chao, Jesse T.; Yashiroda, Yoko; Yoshimura, Mami; Loewen, Christopher J. R.; Gingras, Anne-Claude; Boone, Charles; Av-Gay, Yossef; Roberge, Michel; Andersen, Raymond J.

Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis 高效合成具有胞内结核分枝杆菌活性的苯并噻嗪酮类似物

CHEMMEDCHEM

IF3.4

2021-12-23

OAAI

Richter, Adrian; Narula, Gagandeep; Rudolph, Ines; Seidel, Ruediger W.; Wagner, Christoph; Av-Gay, Yossef; Imming, Peter

Editorial: New Approaches Against Drug-Resistant M. tuberculosis

FRONTIERS IN MICROBIOLOGY

IF4.5

2021-04-15

OAAI

Av-Gay, Yossef; Mori, Giorgia; Pasca, Maria Rosalia

High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity AgainstMycobacterium tuberculosis

FRONTIERS IN MICROBIOLOGY

IF4.5

2020-09-18

OAAI

Shapira, Tirosh; Rankine-Wilson, Leah; Chao, Joseph D.; Pichler, Virginia; Rens, Celine; Pfeifer, Tom; Av-Gay, Yossef

MymA Bioactivated Thioalkylbenzoxazole Prodrug Family Active against Mycobacterium tuberculosis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-04-10

OAAI

Moure, Abraham L.; Narula, Gagandeep; Sorrentino, Flavia; Bojang, Adama; Tsui, Clement K. M.; Emani, Carine Sao; Porras-De Francisco, Esther; Diaz, Beatriz; Jose Rebollo-Lopez, Maria; Alfonso Torres-Gomez, Pedro; Maria Lopez-Roman, Eva; Camino, Isabel; Casado Castro, Patricia; Guijarro Lopez, Laura; Ortega, Faprimetima; Ballell, Lluis; Barros-Aguirre, David; Remuinan Blanco, Modesto; Av-Gay, Yossef

DMN-Tre Labeling for Detection and High-Content Screening of Compounds against Intracellular Mycobacteria

ACS OMEGA

IF4.3

2020-02-14

OAAI

Sahile, Henok A.; Rens, Celine; Shapira, Tirosh; Andersen, Raymond J.; Av-Gay, Yossef

THP-1 and Dictyostelium Infection Models for Screening and Characterization of Anti-Mycobacterium abscessus Hit Compounds

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2019-12-20

OAAI

Richter, Adrian; Shapira, Tirosh; Av-Gay, Yossef

Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-07-31

OAAI

Heinkel, Florian; Abraham, Libin; Ko, Mary; Chao, Joseph; Bach, Horacio; Hui, Lok Tin; Li, Haoran; Zhu, Mang; Ling, Yeou Mei; Rogalski, Jason C.; Scurll, Joshua; Bui, Jennifer M.; Mayor, Thibault; Gold, Michael R.; Chou, Keng C.; Av-Gay, Yossef; McIntosh, Lawrence P.; Gsponer, Jorg

S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-04-02

OAAI

Kaner, Ziv; Engelman, Rotem; Schuster, Ronen; Rider, Peleg; Greenberg, David; Av-Gay, Yossef; Benhar, Moran; Lewis, Eli C.

Screening of Preselected Libraries Targeting Mycobacterium abscessus for Drug Discovery

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2018-09-01

OAAI

Richter, Adrian; Strauch, Angelika; Chao, Joseph; Ko, Mary; Av-Gay, Yossef

Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2018-07-01

PREAI

Laqua, Katja; Klemm, Marcel; Richard-Greenblatt, Melissa; Richter, Adrian; Liebe, Linda; Huang, Tingting; Lin, Shuangjun; Guardia, Ana; Perez-Herran, Esther; Ballell, Lluis; Av-Gay, Yossef; Imming, Peter

Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages

SCIENTIFIC REPORTS

IF3.9

2018-01-09

OAAI

Wong, Dennis; Li, Wu; Chao, Joseph D.; Zhou, Peifu; Narula, Gagandeep; Tsui, Clement; Ko, Mary; Xie, Jianping; Martinez-Frailes, Carlos; Av-Gay, Yossef

Epigenetic Phosphorylation Control of Mycobacterium tuberculosis Infection and Persistence

MICROBIOLOGY SPECTRUM

IF3.8

2017-03-10

PREAI

Richard-Greenblatt, Melissa; Av-Gay, Yossef

Aminorifannycins and Sporalactams Produced in Culture by a Micromonospora sp Isolated from a Northeastern-Pacific Marine Sediment Are Potent Antibiotics

ORGANIC LETTERS

IF5

2017-02-06

PREAI

Williams, David E.; Dalisay, Doralyn S.; Chen, Jessie; Polishchuck, Elena A.; Patrick, Brian O.; Narula, Gagandeep; Ko, Mary; Av-Gay, Yossef; Li, Haoxin; Magarvey, Nathan; Andersen, Raymond J.

Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis

CELL REPORTS

IF6.9

2016-01-01

123

OAAI

Saini, Vikram; Cumming, Bridgette M.; Guidry, Loni; Lamprecht, Dirk A.; Adamson, John H.; Reddy, Vineel P.; Chinta, Krishna C.; Mazorodze, James H.; Glasgow, Joel N.; Richard-Greenblatt, Melissa; Gomez-Velasco, Anaximandro; Bach, Horacio; Av-Gay, Yossef; Eoh, Hyungjin; Rhee, Kyu; Steyn, Adrie J. C.

Development of an Intracellular Screen for New Compounds Able To Inhibit Mycobacterium tuberculosis Growth in Human Macrophages

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2016-01-01

OAAI

Sorrentino, Flavia; Gonzalez del Rio, Ruben; Zheng, Xingji; Presa Matilla, Jesus; Torres Gomez, Pedro; Martinez Hoyos, Maria; Perez Herran, Maria Esther; Mendoza Losana, Alfonso; Av-Gay, Yossef

研究方向