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陈

陈建新 (Jianxin Chen)

South China Agricultural University

H指数:17

被引数:908

个人简介

现任华南农业大学兽医学院研究员、博士生导师，广东省兽药研制与安全评价重点实验室副主任，动物药学专业主任。1989年毕业于武汉大学分析测试科学系，1998年获中国科学院长春应用化学研究所硕士学位，2010年获暨南大学生物医药工程专业博士学位。2003年起在华南农业大学兽医学院从事教学科研工作，2011年晋升为研究员。2013年至2014年作为公派访问学者在澳大利亚La Trobe大学学习研究。研究方向为抗病毒中药药效物质发现及其作用机理。

教育背景

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工作经历

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荣誉奖项

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Biochanin A Exerts Broad-Spectrum Antiviral Activity Against Coronaviruses via Activating the AMPK/Nrf2/GSH Pathway

Biochanin A 通过激活 AMPK/Nrf2/GSH 通路对冠状病毒产生广谱抗病毒活性。

IF4.2

2026-04-100

OAAI

Lapachol, a Dihydroorotate Dehydrogenase Inhibitor, Demonstrates Antiviral Activity against Feline Calicivirus in Vitro and in Vivo

Antiviral Research

IF4

2026-01-210

PRE

Prognostic value of nuclear features based on tumor-associated collagen signatures in breast cancer

基于肿瘤相关胶原特征核特征的预后价值在乳腺癌中

npj Breast Cancer

IF7.6

2025-12-140

OAAI

Early C-reactive protein reduction predicts survival in real-world extensive-stage small cell lung cancer treated with first-line adebrelimab-based immunotherapy

早期C-反应蛋白降低可预测接受一线adebrelimab为基础的免疫疗法治疗的广泛期小细胞肺癌患者的生存情况

Frontiers in Oncology

IF3.3

2025-11-050

OAAI

An Herbal Enema Formula Alleviates Ulcerative Colitis by Inhibiting Enteric Glial Activation via the S100β/RAGE/NF-κB Pathway

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

IF1

2025-11-010

PRE

Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells

盐酸石蒜碱早期增强p38 MAPK信号通路，显著抑制PRRSV在原代和已建立细胞中的增殖。

Frontiers in Microbiology

IF4.5

2025-08-210

OA

Siglec-15 is a putative receptor for porcine epidemic diarrhea virus infection

Siglec-15 是猪流行性腹泻病毒感染的假定受体。

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2025-04-020

OA

Cepharanthine inhibits African swine fever virus replication by suppressing AKT-associated pathways through disrupting Hsp90-Cdc37 complex

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-12-010

OAAI

Chemical profiling of Zhi-Ke-Bao pills and its potential mechanism against cough by ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and network pharmacology

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2024-09-011

PRE

Eugenilones A-N sesquiterpenoids from the fruits of Eugenia uniflora

IF3.4

2023-07-011

PRE

Identification of N- and C-3-Modified Laudanosoline Derivatives as Novel Influenza PAN Endonuclease Inhibitors

鉴定N-和C-3-Modified的Laudanosoline衍生物作为新型流感泛核酸内切酶抑制剂

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-12-158

PRE

Screening and identification of 3-aryl-quinolin-2-one derivatives as antiviral agents against influenza A

JOURNAL OF MEDICAL VIROLOGY

IF4.6

2022-12-051

PRE

Toosendanin suppresses African swine fever virus replication through upregulating interferon regulatory factor 1 in porcine alveolar macrophage cultures

FRONTIERS IN MICROBIOLOGY

IF4.5

2022-08-3014

OAAI

Toosendanin activates caspase-1 and induces maturation of IL-1β to inhibit type 2 porcine reproductive and respiratory syndrome virus replication via an IFI16-dependent pathway

Toosendanin激活caspase-1并诱导IL-1β 成熟通过IFI16-dependent途径抑制2型猪繁殖与呼吸综合征病毒复制

VETERINARY RESEARCH

IF3.5

2022-07-299

OAAI

A total infectome approach to understand the etiology of infectious disease in pigs

IF12.7

2022-05-1016

OAAI

The Antimalaria Drug Artesunate Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by Activating AMPK and Nrf2/HO-1 Signaling Pathways

JOURNAL OF VIROLOGY

IF3.8

2022-02-0923

OA

Prevention and Control Strategies of African Swine Fever and Progress on Pig Farm Repopulation in China

IF3.5

2021-12-2061

OAAI

Major Vault Protein Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection in CRL2843CD163 Cell Lines and Primary Porcine Alveolar Macrophages

IF3.5

2021-11-123

OAAI

Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-04-0116

OAAI

Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-08-2641

OAAI