Juan A. Varela - Publications, H-index & Citations

Juan A. Varela

university of st andrews

27H指数

70论文数

7.1K被引数

收录论文 22

发表时间

Divergent toxicity mechanisms of amyloid-beta aggregates arising from a single aggregation reaction 单一生成聚集反应产生的淀粉样β聚集物的不同毒性机制

Cell Reports

IF6.9

2026-06-22

OAAI

Vanya Metodieva; Sybille Marchese; Pietro Esposito; John S.H. Danial; Andrea Di Falco; Suman De; David Klenerman; Juan A. Varela

Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity 多通路神经退行性蛋白毒性平台揭示DNAJB6促进非毒性FUS凝聚体凝胶化并抑制神经毒性

Nature Communications

IF15.7

2025-11-21

OAAI

Samuel J. Resnick; Seema Qamar; Pushya Krishna; Vladislav Korobeynikov; Hannes Ausserwoger; Alyssa Miller; Pietro Esposito; Juan A. Varela; Jenny Sheng; Lei Haley Huang; Jonathon Nixon-Abell; Schuyler Melore; Chyi Wei Chung; Nino F. Läubli; Sofia Kapsiani; Xuecong Li; Jingshu Wang; Nancy Zhang; Mahabub Maraj Alam; Alondra S. Burguete; Theresa C. Swayne; Yanyan Chen; Ya-Cheng Liao; Neil A. Shneider; Michele Vendruscolo; Tuomas P. J. Knowles; Clemens F. Kaminski; Francesco Simone Ruggeri; Gabriele S. Kaminski Schierle; Peter St George-Hyslop; Alejandro Chavez

Single-molecule imaging of aquaporin-4 array dynamics in astrocytes

NANOSCALE

IF5.1

2024-01-01

OAAI

Zepernick, Anna-Lena; Metodieva, Vanya; Pelegrina-Hidalgo, Noelia; Lippert, Anna H.; Horrocks, Mathew H.; Varela, Juan A.

Suppression of crosstalk in multielectrode arrays with local shielding 具有局部屏蔽的多电极阵列中的串扰抑制

FRONTIERS IN NANOTECHNOLOGY

IF3.8

2022-08-04

OAAI

Naughton, J. R.; Varela, J. A.; Connolly, T. J.; Shepard, S.; Dodge, T. E.; Kempa, K.; Burns, M. J.; Christianson, J. P.; Naughton, M. J.

Structure-specific amyloid precipitation in biofluids

NATURE CHEMISTRY

IF20.2

2022-07-07

OAAI

Rodrigues, M.; Bhattacharjee, P.; Brinkmalm, A.; Do, D. T.; Pearson, C. M.; De, S.; Ponjavic, A.; Varela, J. A.; Kulenkampff, K.; Baudrexel, I; Emin, D.; Ruggeri, F. S.; Lee, J. E.; Carr, A. R.; Knowles, T. P. J.; Zetterberg, H.; Snaddon, T. N.; Gandhi, S.; Lee, S. F.; Klenerman, D.

Insular cortex corticotropin-releasing factor integrates stress signaling with social affective behavior

NEUROPSYCHOPHARMACOLOGY

IF7.1

2022-02-26

OAAI

Rieger, Nathaniel S.; Varela, Juan A.; Ng, Alexandra J.; Granata, Lauren; Djerdjaj, Anthony; Brenhouse, Heather C.; Christianson, John P.

ThX - a next-generation probe for the early detection of amyloid aggregates

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Needham, Lisa-Maria; Weber, Judith; Varela, Juan A.; Fyfe, James W. B.; Do, Dung T.; Xu, Catherine K.; Tutton, Luke; Cliffe, Rachel; Keenlyside, Benjamin; Klenerman, David; Dobson, Christopher M.; Hunter, Christopher A.; Muller, Karin; O'Holleran, Kevin; Bohndiek, Sarah E.; Snaddon, Thomas N.; Lee, Steven F.

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

NATURE COMMUNICATIONS

IF15.7

2019-04-04

150

OAAI

De, Suman; Wirthensohn, David C.; Flagmeier, Patrick; Hughes, Craig; Aprile, Francesco A.; Ruggeri, Francesco S.; Whiten, Daniel R.; Emin, Derya; Xia, Zengjie; Varela, Juan A.; Sormanni, Pietro; Kundel, Franziska; Knowles, Tuomas P. J.; Dobson, Christopher M.; Bryant, Clare; Vendruscolo, Michele; Klenerman, David

Super-Resolution Imaging of the Brain Extracellular Space Deep within Intact Live Tissue using Carbon Nanotubes

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Godin, Antoine G.; Danne, Noemie; Varela, Juan A.; Gao Zhenghong; Lounis, Brahim; Groc, Laurent; Cognet, Laurent

Comparative Analysis of Photoluminescence and Upconversion Emission from Individual Carbon Nanotubes for Bioimaging Applications

ACS PHOTONICS

IF6.7

2017-12-08

PREAI

Danne, Noemie; Godin, Antoine G.; Gao, Zhenghong; Varela, Juan A.; Groc, Laurent; Lounis, Brahim; Cognet, Laurent

Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain

NATURE NANOTECHNOLOGY

IF34.9

2016-11-21

192

OAAI

Godin, Antoine G.; Varela, Juan A.; Gao, Zhenghong; Danne, Noemie; Dupuis, Julien P.; Lounis, Brahim; Groc, Laurent; Cognet, Laurent

Spatial and Structural Metrics for Living Cells Inspired by Statistical Mechanics

SCIENTIFIC REPORTS

IF3.9

2016-10-06

OAAI

Aberg, Christoffer; Varela, Juan A.; Fitzpatrick, Laurence W.; Dawson, Kenneth A.

Single nanoparticle tracking of N-methyl-D-aspartate receptors in cultured and intact brain tissue

NEUROPHOTONICS

IF3.8

2016-07-12

OAAI

Varela, Juan A.; Ferreira, Joana S.; Dupuis, Julien P.; Durand, Pauline; Bouchet, Delphine; Groc, Laurent

Shielded Coaxial Optrode Arrays for Neurophysiology

FRONTIERS IN NEUROSCIENCE

IF3.2

2016-06-09

OAAI

Naughton, Jeffrey R.; Connolly, Timothy; Varela, Juan A.; Lundberg, Jaclyn; Burns, Michael J.; Chiles, Thomas C.; Christianson, John P.; Naughton, Michael J.

Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices

NATURE COMMUNICATIONS

IF15.7

2016-03-14

OAAI

Varela, Juan A.; Dupuis, Julien P.; Etchepare, Laetitia; Espana, Agnes; Cognet, Laurent; Groc, Laurent

Toward the suppression of cellular toxicity from single-walled carbon nanotubes

BIOMATERIALS SCIENCE

IF5.7

2016-01-01

OAAI

Gao, Zhenghong; Varela, Juan A.; Groc, Laurent; Lounis, Brahim; Cognet, Laurent

Trajectory-Based Co-Localization Measures for Nanoparticle-Cell Interaction Studies

SMALL

IF12.1

2014-12-15

PREAI

Varela, Juan A.; Aberg, Christoffer; Simpson, Jeremy C.; Dawson, Kenneth A.

Surface dynamics of GluN2B-NMDA receptors controls plasticity of maturing glutamate synapses

EMBO JOURNAL

IF8.3

2014-03-03

110

OAAI

Dupuis, Julien P.; Ladepeche, Laurent; Seth, Henrik; Bard, Lucie; Varela, Juan; Mikasova, Lenka; Bouchet, Delphine; Rogemond, Veronique; Honnorat, Jerome; Hanse, Eric; Groc, Laurent

Hyper-bright Near-Infrared Emitting Fluorescent Organic Nanoparticles for Single Particle Tracking

ADVANCED MATERIALS

IF26.8

2014-02-03

OAAI

Genin, Emilie; Gao, Zhenghong; Varela, Juan A.; Daniel, Jonathan; Bsaibess, Talia; Gosse, Isabelle; Groc, Laurent; Cognet, Laurent; Blanchard-Desce, Mireille

Quantitative Assessment of the Comparative Nanoparticle-Uptake Efficiency of a Range of Cell Lines

SMALL

IF12.1

2011-10-19

227

OAAI

dos Santos, Tiago; Varela, Juan; Lynch, Iseult; Salvati, Anna; Dawson, Kenneth A.

研究方向