Peter B. Dirks - Publications, H-index & Citations

Peter B. Dirks

Hospital for Sick Children

84H指数

709论文数

4.5W被引数

收录论文 162

发表时间

Ultrasound-Enhanced Drug Delivery in Pediatric Neuro-Oncology: A New Therapeutic Strategy 超声增强的儿童神经肿瘤学药物递送：一种新的治疗策略

Pharmaceutics

IF5.5

2026-05-07

OAAI

Elora Weber; Christian A. Smith; Cynthia Hawkins; Uri Tabori; Peter B. Dirks; James T. Rutka

Glioblastoma stem cells show transcriptionally correlated spatial organization 胶质母细胞瘤干细胞显示转录相关的空间组织

Communications Biology

IF5.1

2026-01-23

OAAI

Shamini Ayyadhury; Patty Sachamitr; Michelle M. Kushida; Nicole I. Park; Fiona J. Coutinho; Owen Whitley; Panagiotis Prinos; Cheryl H. Arrowsmith; Peter B. Dirks; Trevor J. Pugh; Gary D. Bader

Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma 错配修复缺陷型神经胶质瘤的高突变形状肿瘤发生和免疫治疗反应的模式

Nature Genetics

IF29

2025-12-22

PREAI

Nicholas R. Fernandez; Yuan Chang; Nuno M. Nunes; Jose R. Dimayacyac; Adrian Levine; Amit Ringel; Logine Negm; Ayse Bahar Ercan; Julian M. Hess; Olfat Ahmad; Caitlin Lee; Lucie Stengs; Vanessa Bianchi; Melissa Edwards; Sheradan Doherty; Jiil Chung; Liana Nobre; Julie Bennett; Andrew J. Dodgshun; David T. W. Jones; Stefan M. Pfister; Anita Villani; David Malkin; Vijay Ramaswamy; Annie Huang; Eric Bouffet; Melyssa Aronson; Peter B. Dirks; Adam Shlien; Gad Getz; Yosef E. Maruvka; Birgit Ertl-Wagner; Cynthia Hawkins; Anirban Das; Uri Tabori

Segmentation-free pretherapeutic assessment of BRAF-status in pediatric low-grade gliomas 无分割预治疗评估儿童低级别胶质瘤的BRAF状态

Communications Medicine

IF6.3

2025-11-27

OAAI

Kareem Kudus; Matthias Wagner; Min Sheng; Julie Bennett; Anthony Liu; Peter Dirks; Uri Tabori; Cynthia Hawkins; Birgit Betina Ertl-Wagner; Farzad Khalvati

Multiclass machine learning models for molecular subtype identification of pediatric low-grade glioma using bi-institutional MRIs for precision medicine 基于双机构MRI的儿童低级别胶质瘤分子亚型识别的多分类机器学习模型研究

npj Precision Oncology

IF8

2025-11-17

OAAI

Khashayar Namdar; Matthias W. Wagner; Min Sheng; Peter Dirks; Kristen W. Yeom; Cynthia Hawkins; Uri Tabori; Birgit B. Ertl-Wagner; Farzad Khalvati

TRACING THE ORIGINS OF H3.3K27M MUTANT DIFFUSE MIDLINE GLIOMA 追溯H3.3K27M突变弥漫性中线胶质瘤的起源

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Herrington, Caitlin; Lubanszky, Evan; Trinh, Quang; Pontual, Luiza Lopes; Forst, Jannine; Hawkins, Cynthia; Dirks, Peter

Integrated clinical and molecular landscape of disseminated pediatric low-grade glioma 整合的播散性儿童低级别胶质瘤临床与分子全景

Neuro-Oncology

IF13.4

2025-10-21

PREAI

Adrian B Levine; Julie Bennett; Prabhumallikarjun Patil; Ian Burns; Robert Siddaway; Cyril Li; Joseline Haizel-Cobbina; Mansuba Rana; Richard Yuditskiy; Andrew Son; Yoshiko Nakano; Palak Patel; I-Chen Ho; Michelle Ku; Alexander T Lyons; José E Velázquez Vega; Matthew J Schniederjan; Craig Erker; Chantel Cacciotti; Mariarita Santi; Ernest J Nelson; Sylvia Cheng; Christopher Dunham; Bev Wilson; Karina Black; Frank Van Landeghem; Liana Nobre; David D Eisenstat; Ana S Guerreiro Stücklin; Annette Weiser; Valerie Larouche; Panagiota Giannakouros; Adriana Fonseca; Lane Williamson; Igor L Fernandes; Ashley S Plant-Fox; Adam Fleming; Shawde Campbell; Naureen Mushtaq; Syed Ibrahim Bukhari; Khurram Minhas; Richard T Graham; Scott Raskin; Filip Jadrijevic-Cvrlje; Louise Ludlow; Mary V Macneil; Jean M Mulcahy-Levy; Samantha Demarsh; Kohei Fukuoka; Kai Yamasaki; Tomonari Suzuki; Fumiharu Ohka; Atsufumi Kawamura; Yoshiki Arakawa; Takashi Ishihara; Fumiyuki Yamasaki; Jordan R Hansford; Amanda Luck; Maclean P Nasrallah; Helen Toledano; Roaya M Masoud; Alvaro Lassaletta; Luis Blasco-Santana; John-Paul Kilday; Alisa Talianski; Caroline Davies; James Johnston; Andrew T Hale; Peter B Dirks; James T Rutka; Michael C Dewan; Uri Tabori; Cynthia E Hawkins

Targeting synthetic lethality between non-homologous end joining and radiation in very-high-risk medulloblastoma 靶向非同源末端连接与辐射之间的合成致死作用以治疗极高危性髓母细胞瘤

Cell Reports Medicine

IF10.6

2025-06-24

OAAI

Alexandria DeCarlo; Graham MacLeod; Carolina Fernandes da Silva; Li Qing Shen; Julija Povilaikaite; Madeline Deane; Lucas Aragao; Mariska Sie; Deborah Termini; Jonathan Magee; Brian Gudenas; Sneha Sukumaran; Frederic Charron; Richard Marcellus; Rima Al-Awar; Ahmed Aman; Denis Reynaud; Amarine Trolat; Leanne Wybenga-Groot; Uri Tabori; Carolina Nör; Shane M. Harding; Michael F. Moran; Paul A. Northcott; Peter Dirks; Stephane Angers; Vijay Ramaswamy

Re-irradiation for children with diffuse intrinsic pontine glioma and diffuse midline glioma 复发弥漫性内生性脑桥胶质瘤和弥漫性中线胶质瘤儿童的重照射治疗

RADIOTHERAPY AND ONCOLOGY

IF5.3

2025-06-01

OAAI

Shariff, Nisha; Moreno, Alejandro S.; Bennett, Julie; Ramaswamy, Vijay; Das, Anirban; Liu, Anthony P.; Huang, Annie; Tabori, Uri; Hawkins, Cynthia; Dirks, Peter; Bouffet, Eric; Keilty, Dana M.; Millar, Barbara-Ann; Hodgson, David C.; Tsang, Derek S.

Importin-alpha transports Norrin to the nucleus to promote proliferation and Notch signaling in glioblastoma stem cells Importin-alpha将Norrin转运至细胞核，以促进胶质母细胞瘤干细胞增殖和Notch信号通路。

ONCOGENE

IF7.3

2025-05-27

PREAI

El-Sehemy, Ahmed; Tachibana, Nobuhiko; Ortin-Martinez, Arturo; Ringuette, Dene; Coyaud, Etienne; Raught, Brian; Dirks, Peter; Wallace, Valerie A.

Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration Wu, Y.; Wu, B.Z.; Ellenbogen, Y.; Kant, J.B.Y.; Yu, P.; Li, X.; Caloren, L.; Sotov, V.; Tran, C.; Restrepo, M.; 等. 少突胶质细胞系程序神经发育劫持驱动胶质母细胞瘤浸润。Dev. Cell 2025. [Google Scholar] [CrossRef]

Developmental Cell

IF8.7

2025-05-16

OAAI

Yiyan Wu; Benson Z. Wu; Yosef Ellenbogen; Joan B.Y. Kant; Pengcheng Yu; Xuyao Li; Loïc Caloren; Valentin Sotov; Christine Tran; Michelle Restrepo; Michelle Kushida; Shamini Ayyadhury; Pathum Kossinna; Ruth Lau; Parnian Habibi; Sheila Mansouri; Johanna Regala; Tanja Durbic; Farzaneh Aboualizadeh; Julissa Tsao; Troy Ketela; Trevor Pugh; Marcus O. Butler; Ben X. Wang; Peter B. Dirks; Andrew Gao; Gelareh Zadeh; Federico Gaiti

A population-based analysis of the molecular landscape of glioma in adolescents and young adults reveals insights into gliomagenesis 基于人群的胶质瘤分子景观分析揭示了青少年和年轻成人胶质瘤发生的见解

NATURE CANCER

IF28.5

2025-05-07

PREAI

Bennett, Julie; Levine, Adrian B.; Nobre, Liana; Negm, Logine; Chung, Jiil; Fang, Karen; Johnson, Monique; Komosa, Martin; Krumholtz, Stacey; Nunes, Nuno Miguel; Rana, Mansuba; Ryall, Scott; Sheth, Javal; Siddaway, Robert; Bale, Tejus A.; Bouffet, Eric; Cusimano, Michael D.; Das, Sunit; Detsky, Jay; Dirks, Peter; Karajannis, Matthias A.; Kongkham, Paul; Giantini-Larsen, Alexandra; Li, Bryan Kincheon; Lim-Fat, Mary Jane; Lin, Andrew L.; Mason, Warren P.; Miller, Alexandra; Perry, James R.; Sahgal, Arjun; Sait, Sameer Farouk; Tsang, Derek S.; Zadeh, Gelareh; Laperriere, Normand; Nguyen, Lananh; Gao, Andrew; Keith, Julia; Munoz, David G.; Tabori, Uri; Hawkins, Cynthia

OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma OLIG2 介导了一种罕见的可靶向的干细胞命运转换，在 sonic hedgehog medulloblastoma 中。

NATURE COMMUNICATIONS

IF15.7

2025-02-04

OAAI

Desai, Kinjal; Wanggou, Siyi; Luis, Erika; Whetstone, Heather; Yu, Chunying; Vanner, Robert J.; Selvadurai, Hayden J.; Lee, Lilian; Vijay, Jinchu; Jaramillo, Julia E.; Fan, Jerry; Guilhamon, Paul; Kushida, Michelle; Li, Xuejun; Stein, Gregory; Kesari, Santosh; Simons, Benjamin D.; Huang, Xi; Dirks, Peter B.

High detection rate of circulating-tumor DNA from cerebrospinal fluid of children with central nervous system germ cell tumors 中枢神经系统生殖细胞肿瘤患儿脑脊液循环肿瘤DNA的高检出率

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-11-20

OAAI

Nakano, Yoshiko; Burns, Ian; Nobre, Liana; Siddaway, Robert; Rana, Mansuba; Nesvick, Cody; Bondoc, Andrew; Ku, Michelle; Yuditskiy, Richard; Ku, Dennis T. L.; Shing, Matthew M. K.; Cheng, Kevin K. F.; Ng, Ho-Keung; Das, Anirban; Bennett, Julie; Ramaswamy, Vijay; Huang, Annie; Malkin, David; Ertl-Wagner, Birgit; Dirks, Peter; Bouffet, Eric; Bartels, Ute; Tabori, Uri; Hawkins, Cynthia; Liu, Anthony P. Y.

TRANSLATING COMBINED PD1 AND LAG3 INHIBITION FROM PRECLINICAL MODELS TO PATIENTS WITH REFRACTORY, DNA REPLICATION REPAIR DEFICIENT (RRD) GLIOBLASTOMA: AN IRRDC STUDY

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Das, Anirban; Crump, Owen; Kos, Olha; Nunes, Nuno; Stengs, Lucie; Li, Amanda; Levine, Adrian; Nakano, Yoshiko; Friedman, Hope; O'Flaherty, Katharine; Stein, Alexander; Abebe-Campino, Gadi; Bronsema, Annika; Bianchi, Vanessa; Edwards, Melissa; Zacharoulis, Stergios; Ertl-Wagner, Birgit; Morgenstern, Daniel; Pugh, Trevor; Ohashi, Pamela; Bouffet, Eric; Hawkins, Cynthia; Dirks, Peter; Tabori, Uri

TRANS-SPECIES STUDY OF IDH-MUTANT REPLICATION-REPAIR DEFICIENT HIGH-GRADE GLIOMAS (RRD-HGG) AND RESPONSE TO COMBINED TARGETED AND IMMUNOTHERAPY: AN IRRDC STUDY

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Das, Anirban; Mazzoli, Vienna; Fernandez, Nicholas; Aamir, Zoya; Nunes, Nuno; O'Flaherty, Katharine; Friedman, Hope; Bielamowicz, Kevin; Abebe-Campino, Gadi; Caspi, Shani; Nyman, Per; Graham, Richard; Kim, John; Wilhelmsson, Mari; Jorgensen, Mette; Michaeli, Orli; Fernandez, Maria; Reddy, Alyssa; Llosa, Nicholas; Li, Amanda; Levin, Adrian; Stengs, Lucie; Negm, Logine; Bianchi, Vanessa; Edwards, Melissa; Ertl-Wagner, Birgit; Bennett, Julie; Dirks, Peter; Bouffet, Eric; Hawkins, Cynthia; Tabori, Uri

Neurocognitive outcomes following intracerebral hemorrhage in childhood 儿童期脑出血后的神经认知结局

CHILD NEUROPSYCHOLOGY

IF1.9

2024-10-29

PREAI

Champigny, Claire M.; Kahnami, Leila; Isaacs, Tamiko; Beribisky, Nataly; Desrocher, Mary; Feldman, Samantha J.; Krishnan, Pradeep; Dlamini, Nomazulu; Dirks, Peter; Westmacott, Robyn

Central nervous system tumors in adolescents and young adults: A Society for Neuro-Oncology consensus review on diagnosis, management, and future directions

NEURO-ONCOLOGY

IF13.4

2024-10-23

PREAI

Lim-Fat, Mary Jane; Bennett, Julie; Ostrom, Quinn; Touat, Mehdi; Franceschi, Enrico; Schulte, Jessica; Bindra, Ranjit S.; Fangusaro, Jason; Dhall, Girish; Nicholson, James; Jackson, Sadhana; Davidson, Tom Belle; Calaminus, Gabriele; Robinson, Giles; Whittle, James R.; Hau, Peter; Ramaswamy, Vijay; Pajtler, Kristian W.; Ruda, Roberta; Foreman, Nicholas K.; Hervey-Jumper, Shawn L.; Das, Sunit; Dirks, Peter; Bi, Wenya Linda; Huang, Annie; Merchant, Thomas E.; Fouladi, Maryam; Aldape, Kenneth; van den Bent, Martin J.; Packer, Roger J.; Miller, Julie J.; Reardon, David A.; Chang, Susan M.; Haas-Kogan, Daphne; Tabori, Uri; Hawkins, Cynthia; Monje, Michelle; Wen, Patrick Y.; Bouffet, Eric; Yeo, Kee Kiat

Magnetic Resonance Angiography Alone Is Insufficient for Diagnosis and Surgical Planning in Children With Moyamoya

PEDIATRIC NEUROLOGY

IF2.1

2024-10-01

PREAI

Lehman, Laura L.; Wu, Clara; Kaseka, Matsanga-Leyila; Muthusami, Prakash; Armstrong, Derek; Dirks, Peter; Shroff, Manohar; Moharir, Mahendranath; Macgregor, Daune; deVeber, Gabrielle; Dlamini, Nomazulu

Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities

CANCER RESEARCH

IF16.6

2024-08-26

PREAI

Macleod, Graham; Molaei, Fatemeh; Haider, Shahan; Almeida, Maira P.; Lin, Sichun; Kushida, Michelle; Sureshkumar, Haresh; Bhatti, Jasmine K.; Lu, Jack Q.; Schramek, Daniel; Dirks, Peter B.; Angers, Stephane

研究方向