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收藏Genetic impairment in myosin-5b related transport processes mediates cardiac dysfunction and sudden cardiac death肌球蛋白5b相关的运输过程中的遗传缺陷介导了心脏功能障碍和心源性猝死。
Ricke-Hoch, Melanie; Heimerl, Maren; Erschow, Sergej; Mueller-Olling, Mirco; Manstein, Dietmar; Decher, Niels; Kauferstein, Silke; Jenewein, Tina; Pich, Andreas; Hilfiker-Kleiner, Denise 分享 收藏 KCNQ1 is an essential mediator of the sex- dependent perception of moderate cold temperaturesKiper, Aytug K.; Wegner, Sven; Kadala, Aklesso; Rinne, Susanne; Schuette, Sven; Winter, Zoltan; Bertoune, Mirjam A. R.; Touska, Filip; Matschke, Veronika; Wrobel, Eva; Streit, Anne-Kathrin; Lang, Florian; Schmidt, Constanze; Schulze-Bahr, Eric; Schaefer, Martin K. - H.; Voelkl, Jakob; Seebohm, Guiscard; Zimmermann, Katharina; Decher, Niels 分享 收藏 Cloxyquin activates hTRESK by allosteric modulation of the selectivity filterSchreiber, Julian Alexander; Derksen, Anastasia; Goerges, Gunnar; Schuette, Sven; Soergel, Jasmin; Kiper, Aytug K.; Strutz-Seebohm, Nathalie; Ruck, Tobias; Meuth, Sven G.; Decher, Niels; Seebohm, Guiscard 分享 收藏 Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking (vol 11, 4, 2023)Swan, Alexander H.; Schindler, Roland F. R.; Savarese, Marco; Mayer, Isabelle; Rinne, Susanne; Bleser, Felix; Schaenzer, Anne; Hahn, Andreas; Sabatelli, Mario; Perna, Francesco; Chapman, Kathryn; Pfuhl, Mark; Spivey, Alan C.; Decher, Niels; Udd, Bjarne; Tasca, Giorgio; Brand, Thomas 分享 收藏 Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular functionVera-Zambrano, Alba; Baena-Nuevo, Maria; Rinne, Susanne; Villegas-Esguevillas, Marta; Barreira, Bianca; Telli, Gokcen; de Benito-Bueno, Angela; Blazquez Jose, Antonio; Climent, Belen; Perez-Vizcaino, Francisco; Valenzuela, Carmen; Decher, Niels; Gonzalez, Teresa; Cogolludo, Angel 分享 收藏 Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane traffickingSwan, Alexander H.; Schindler, Roland F. R.; Savarese, Marco; Mayer, Isabelle; Rinne, Susanne; Bleser, Felix; Schaenzer, Anne; Hahn, Andreas; Sabatelli, Mario; Perna, Francesco; Chapman, Kathryn; Pfuhl, Mark; Spivey, Alan C.; Decher, Niels; Udd, Bjarne; Tasca, Giorgio; Brand, Thomas 分享 收藏 Selective TASK-1 Inhibitor with a Defined Structure-Activity Relationship Reduces Cancer Cell Proliferation and ViabilityArevalo, Barbara; Bedoya, Mauricio; Kiper, Aytug K.; Vergara, Fernando; Ramirez, David; Mazola, Yuliet; Bustos, Daniel; Zuniga, Rafael; Cikutovic, Rocio; Cayo, Angel; Rinne, Susanne; Teresa Ramirez-Apan, M.; Sepulveda, Francisco, V; Cerda, Oscar; Lopez-Collazo, Eduardo; Decher, Niels; Zuniga, Leandro; Gutierrez, Margarita; Gonzalez, Wendy 分享 收藏 POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK-1 in heartBaldwin, Tanya A.; Li, Yong; Marsden, Autumn N.; Rinne, Susanne; Garza-Carbajal, Anibal; Schindler, Roland F. R.; Zhang, Musi; Garcia, Mia A.; Venna, Venugopal Reddy; Decher, Niels; Brand, Thomas; Dessauer, Carmen W. 分享 收藏 分享 收藏 A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncouplingSchreiber, Julian A.; Moeller, Melina; Zaydman, Mark; Zhao, Lu; Beller, Zachary; Becker, Sebastian; Ritter, Nadine; Hou, Panpan; Shi, Jingyi; Silva, Jon; Wrobel, Eva; Strutz-Seebohm, Nathalie; Decher, Niels; Schmitt, Nicole; Meuth, Sven G.; Duefer, Martina; Wuensch, Bernhard; Cui, Jianmin; Seebohm, Guiscard 分享 收藏 Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's diseaseMatschke, Lina A.; Komadowski, Marlene A.; Stoehr, Annette; Lee, Bolam; Henrich, Martin T.; Griesbach, Markus; Rinne, Susanne; Geibl, Fanni F.; Chiu, Wei-Hua; Koprich, James B.; Brotchie, Jonathan M.; Kiper, Aytug K.; Dolga, Amalia M.; Oertel, Wolfgang H.; Decher, Niels 分享 收藏 5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective SynthesisRamirez, David; Mejia-Gutierrez, Melissa; Insuasty, Braulio; Rinne, Susanne; Kiper, Aytug K.; Platzk, Magdalena; Mueller, Thomas; Decher, Niels; Quiroga, Jairo; De-la-Torre, Pedro; Gonzalez, Wendy 分享 收藏 Treatment of atrial fibrillation with doxapram: TASK-1 potassium channel inhibition as a novel pharmacological strategyWiedmann, Felix; Beyersdorf, Christoph; Zhou, Xiao-Bo; Kraft, Manuel; Paasche, Amelie; Javorszky, Natasa; Rinne, Susanne; Sutanto, Henry; Buscher, Antonius; Foerster, Kathrin, I; Blank, Antje; El-Battrawy, Ibrahim; Li, Xin; Lang, Siegfried; Tochtermann, Ursula; Kremer, Jamila; Arif, Rawa; Karck, Matthias; Decher, Niels; van Loon, Gunther; Akin, Ibrahim; Borggrefe, Martin; Kallenberger, Stefan; Heijman, Jordi; Haefeli, Walter E.; Katus, Hugo A.; Schmidt, Constanze 分享 收藏 Identification of a critical binding site for local anaesthetics in the side pockets of Kv1 channelsKiper, Aytug K.; Bedoya, Mauricio; Stalke, Sarah; Marzian, Stefanie; Ramirez, David; de la Cruz, Alicia; Peraza, Diego A.; Vera-Zambrano, Alba; Marquez Montesinos, Jose C. E.; Arevalo Ramos, Barbara A.; Rinne, Susanne; Gonzalez, Teresa; Valenzuela, Carmen; Gonzalez, Wendy; Decher, Niels 分享 收藏 分享 收藏 POPDC2 a novel susceptibility gene for conduction disordersRinne, Susanne; Ortiz-Bonnin, Beatriz; Stallmeyer, Birgit; Kiper, Aytug K.; Fortmueller, Lisa; Schindler, Roland F. R.; Herbort-Brand, Ursula; Kabir, Nashitha S.; Dittmann, Sven; Friedrich, Corinna; Zumhagen, Sven; Gualandi, Francesca; Selvatici, Rita; Rapezzi, Claudio; Arbustini, Eloisa; Ferlini, Alessandra; Fabritz, Larissa; Schulze-Bahr, Eric; Brand, Thomas; Decher, Niels 分享 收藏 Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neuronsGanjam, Goutham K.; Bolte, Kathrin; Matschke, Lina A.; Neitemeier, Sandra; Dolga, Amalia M.; Hoellerhage, Matthias; Hoeglinger, Guenter U.; Adamczyk, Agata; Decher, Niels; Oertel, Wolfgang H.; Culmsee, Carsten 分享 收藏 POPDC3 Gene Variants Associate with a New Form of Limb Girdle Muscular DystrophyVissing, John; Johnson, Katherine; Topf, Ana; Nafissi, Shahriar; Diaz-Manera, Jordi; French, Vanessa M.; Schindler, Roland F.; Sarathchandra, Padmini; Lokken, Nicoline; Rinne, Susanne; Freund, Max; Decher, Niels; Mueller, Thomas; Duno, Morten; Krag, Thomas; Brand, Thomas; Straub, Volker 分享 收藏 Ubiquitylome profiling of Parkin-null brain reveals dysregulation of calcium homeostasis factors ATP1A2, Hippocalcin and GNA11, reflected by altered firing of noradrenergic neuronsKey, J.; Mueller, A. K.; Gispert, S.; Matschke, L.; Wittig, I; Corti, O.; Muench, C. H.; Decher, N.; Auburger, G. 分享 收藏 
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