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B

Bram Boeckx

flanders institute for biotechnology (vib)
H指数:41
被引数:1.3万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Pan-cancer single-cell atlases of mouse and human tumor-associated dendritic cells

小鼠和人类肿瘤相关树突状细胞的泛癌单细胞图谱

Nature Communications
IF15.7
2026-05-300
OAAI
Aarushi A. Caro; Daliya Kancheva; Eva Hadadi; Bram Boeckx; Clint De Nolf; Pauline M. R. Bardet; Kevin Verstaen; Luqing Li; Lobna Oueslati; Nil Figueras-Duch; Yvon Elkrim; Niels Vandamme; Sofie Deschoemaeker; Arnaud Blomme; Pierre Close; Sophie Janssens; Michele De Palma; Diether Lambrechts; An Coosemans; Damya Laoui
Integrated multi-omics identifies distinct macrophage alterations during progression of metabolic dysfunction-associated steatohepatitis

整合多组学分析揭示代谢功能障碍相关脂肪性肝炎进展过程中巨噬细胞的特异性改变

Nature Genetics
IF29
2026-05-180
OAAI
Markus Boesch; Seray Anak; Dania El Abyad; Tessa Ostyn; Asier Antoranz; Trieu My Van; Daniel Newhouse; Caitlyn Myers; Lukas Van Melkebeke; Jeremy Palmer; Najmeh Saffarzadeh; Jonathan Sai-Hong Chui; Rita Feio-Azevedo; Lena Smets; Gautam Shankar; Nikolina Dubroja Lakić; Paula Longás Calvo; Thierry Voet; James Clark; Simon Cockell; Matthias Lannoo; Ellen Deleus; Joris Jaekers; Halit Topal; Baki Topal; Kai Markus Schneider; Michele Vacca; Michael Allison; Mattias Ekstedt; Jerome Boursier; Elisabetta Bugianesi; Vlad Ratziu; Frederik De Smet; Bram Boeckx; Ann K. Daly; Jörn M. Schattenberg; Jef Verbeek; Francesca Bosisio; Diether Lambrechts; Tania Roskams; Carolin V. Schneider; Sven Francque; Hannelie Korf; Anetta Härtlova; Dina Tiniakos; Quentin M. Anstee; Schalk van der Merwe; Olivier Govaere
Single-nucleus profiling reveals hepatocyte identity and immune features associated with corticosteroid response in severe alcohol-related hepatitis

单核分析揭示了严重酒精相关性肝炎中与皮质类固醇反应相关的肝细胞身份和免疫特征

Journal of Hepatology
IF33
2026-04-200
PRE
Lukas Van Melkebeke; Markus Boesch; Tessa Ostyn; Wenxin Huang; Cansu Akkaya; Matthias van Sligtenhorst; Dania El Abyad; Fateme Safaeifard; Alexander Dumarey; Marie Wallays; Bram Boeckx; Rita Feio-Azevedo; Lena Smets; Thierry Gustot; Eric Trepo; Christophe Moreno; Antonella Putignano; Luc Lasser; Isabelle Colle; Pierre Deltenre
A pipeline of machine learning-driven multi-modal data fusion methods for prognostic risk analysis in bevacizumab-treated metastatic colorectal cancer

一种基于机器学习的多模态数据融合方法流程，用于贝伐珠单抗治疗转移性结直肠癌的预后风险分析

Scientific Reports
IF3.9
2026-04-010
OAAI
Thomas, Valentina; Nyamundanda, Gift; Larkeryd, Adrian; Hari, P. S.; Miller, Ian S.; Venken, Tom; Smeets, Dominiek; Boeckx, Bram; Betge, Johannes; Ebert, Matthias P. A.; Gaiser, Timo; Murphy, Verena; Kay, Elaine; Verheul, Henk M.; O'Farrell, Alice C.; Cremolini, Chiara; Marmorino, Federica; Gallagher, William M.; Barat, Ana; Klinger, Rut; Fender, Bozena; Ylstra, Bauke; van Grieken, Nicole; McNamara, Deborah A.; Hennessy, Bryan T.; Das, Sudipto; Moran, Bruce; O'Connor, Darran P.; Dienstmann, Rodrigo; Lambrechts, Diether; Prehn, Jochen H. M.; Sadanandam, Anguraj; Byrne, Annette T.
Expression of antibody-drug conjugate targets in post-mortem samples of breast cancer metastases and normal tissue

抗体偶联药物靶点在乳腺癌转移灶和正常组织死后样本中的表达

Nature Communications
IF15.7
2025-12-260
OAAI
Kristien Borremans; Anirudh Pabba; Gitte Zels; Amena Mahdami; Camille Carette; Marion Maetens; Karen Van Baelen; Josephine Van Cauwenberge; Ha Linh Nguyen; Hava Izci; Sophia Leduc; Sigrid Hatse; Madita Nysen; Bram Boeckx; Evy Vanderheyden; Thomas Van Brussel; Françoise Derouane; Kevin Punie; Wouter Van Den Bogaert; Peter Vermeulen; Elia Biganzoli; Diether Lambrechts; Patrick Neven; Hans Wildiers; Giuseppe Floris; François Richard; Christine Desmedt
ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer

ctDNA在转移性乳腺癌患者七种体液中的检测性与代表性

Nature Communications
IF15.7
2025-12-020
OAAI
François Richard; Marion Maetens; Karen Van Baelen; Kristien Borremans; Josephine Van Cauwenberge; Gitte Zels; Emma Rousseau; Tatjana Geukens; Maxim De Schepper; Amena Mahdami; Evy Vanderheyden; Thomas Van Brussel; Ha-Linh Nguyen; Anirudh Pabba; Sophia Leduc; Hava Izci; Imane Bachir; Camille Carette; Sigrid Hatse; Madita Nysen; Peter Vermeulen; Bram Boeckx; Diether Lambrechts; Elia Biganzoli; Patrick Neven; Hans Wildiers; Wouter Van Den Bogaert; Jonas Demeulemeester; Giuseppe Floris; Christine Desmedt
Enhancing translational research in metastatic cancer through an open science environment: the UPTIDER experience

通过开放科学环境增强转移性癌症的转化研究：UPTIDER项目经验

npj Precision Oncology
IF8
2025-11-060
OAAI
Anirudh Pabba; Marion Maetens; Amena Mahdami; Tatjana Geukens; Maxim De Schepper; Gitte Zels; Karen Van Baelen; Sophia Leduc; Ha Linh Nguyen; Josephine Van Cauwenberge; Kristien Borremans; Sigrid Hatse; Madita Nysen; Emma Rousseau; Angelica Di Tommaso; Bram Boeckx; Patrick Neven; Hans Wildiers; Elia Biganzoli; Peter Vermeulen; Wouter Van Den Bogaert; Diether Lambrechts; Giuseppe Floris; Christine Desmedt; François Richard
Decoding tumor heterogeneity: A spatially informed pan-cancer analysis of the tumor microenvironment

解码肿瘤异质性：一项关于肿瘤微环境的基于空间信息的泛癌分析

Cell Reports Medicine
IF10.6
2025-10-140
OAAI
Francesca Lodi; Sam Vanmassenhove; Duojiao Chen; Bram Boeckx; Lucas Ferreira Maciel; Frederik Peeters; Elena Donders; Heesoo Song; Luuk Harbers; Joanna Poźniak; Liselore Loverix; Yiduo Zhou; Michel Bila; Ayse Bassez; Sarah Cappuyns; Tom Venken; Siel Olbrecht; Amelie Franken; Pierre Van Mol; Rogier Schepers; Thomas van Brussel; Gino Philips; Hanne Vos; Machteld Keupers; Frederik De Smet; Sabine Tejpar; Oliver Bechter; Gabriele Bergers; Ann Smeets; Paul Clement; Els Wauters; Jeroen Dekervel; Toon Van Gorp; Junbin Qian; Jean-Christophe Marine; Diether Lambrechts
Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial

新辅助nivolumab或nivolumab联合ipilimumab治疗早期三阴性乳腺癌: 2期适应性试验

NATURE MEDICINE
IF50
2024-09-162
OAAI
Nederlof, Iris; Isaeva, Olga I.; de Graaf, Manon; Gielen, Robbert C. A. M.; Bakker, Noor A. M.; Rolfes, Adrianne L.; Garner, Hannah; Boeckx, Bram; Traets, Joleen J. H.; Mandjes, Ingrid A. M.; de Maaker, Michiel; van Brussel, Thomas; Chelushkin, Maksim; Champanhet, Elisa; Lopez-Yurda, Marta; van de Vijver, Koen; van den Berg, Jose G.; Hofland, Ingrid; Klioueva, Natasja; Mann, Ritse M.; Loo, Claudette E.; van Duijnhoven, Frederieke H.; Skinner, Victoria; Luykx, Sylvia; Kerver, Emile; Kalashnikova, Ekaterina; van Dongen, Marloes G. J.; Sonke, Gabe S.; Linn, Sabine C.; Blank, Christian U.; de Visser, Karin E.; Salgado, Roberto; Wessels, Lodewyk F. A.; Drukker, Caroline A.; Schumacher, Ton N.; Horlings, Hugo M.; Lambrechts, Diether; Kok, Marleen
A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma ( vol 30 , pg 1667 , 2024)
NATURE MEDICINE
IF50
2024-07-151
PRE
Kinget, Lisa; Naulaerts, Stefan; Govaerts, Jannes; Vanmeerbeek, Isaure; Sprooten, Jenny; Laureano, Raquel S.; Dubroja, Nikolina; Shankar, Gautam; Bosisio, Francesca M.; Roussel, Eduard; Verbiest, Annelies; Finotello, Francesca; Ausserhofer, Markus; Lambrechts, Diether; Boeckx, Bram; Wozniak, Agnieszka; Boon, Louis; Kerkhofs, Johan; Zucman-Rossi, Jessica; Albersen, Maarten; Baldewijns, Marcella; Beuselinck, Benoit; Garg, Abhishek D.
Single-cell RNA sequencing of cystic fibrosis liver disease explants reveals endothelial complement activation

囊性纤维化肝病外植体的单细胞RNA测序揭示了内皮补体激活

LIVER INTERNATIONAL
IF5.2
2024-06-073
PRE
Declercq, Mathias; Treps, Lucas; Geldhof, Vincent; Conchinha, Nadine V.; de Rooij, Laura P. M. H.; Subramanian, Abhishek; Feyeux, Magalie; Cotinat, Marine; Boeckx, Bram; Vinckier, Stefan; Dupont, Lieven; Vermeulen, Francois; Boon, Mieke; Proesmans, Marijke; Libbrecht, Louis; Pirenne, Jacques; Monbaliu, Diethard; Jochmans, Ina; Dewerchin, Mieke; Eelen, Guy; Roskams, Tania; Verleden, Stijn; Lambrechts, Diether; Carmeliet, Peter; Witters, Peter
A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma
NATURE MEDICINE
IF50
2024-05-217
PRE
Kinget, Lisa; Naulaerts, Stefan; Govaerts, Jannes; Vanmeerbeek, Isaure; Sprooten, Jenny; Laureano, Raquel S.; Dubroja, Nikolina; Shankar, Gautam; Bosisio, Francesca M.; Roussel, Eduard; Verbiest, Annelies; Finotello, Francesca; Ausserhofer, Markus; Lambrechts, Diether; Boeckx, Bram; Wozniak, Agnieszka; Boon, Louis; Kerkhofs, Johan; Zucman-Rossi, Jessica; Albersen, Maarten; Baldewijns, Marcella; Beuselinck, Benoit; Garg, Abhishek D.
Distinct immunometabolic signatures in circulating immune cells define disease outcome in acute-on-chronic liver failure
HEPATOLOGY
IF15.8
2024-05-162
OAAI
Feio-Azevedo, Rita; Boesch, Markus; Radenkovic, Silvia; van Melkebeke, Lukas; Smets, Lena; Wallays, Marie; Boeckx, Bram; Philips, Gino; Prata de Oliveira, Janaine; Ghorbani, Mohammad; Laleman, Wim; Meersseman, Philippe; Wilmer, Alexander; Cassiman, David; van Malenstein, Hannah; Triantafyllou, Evangelos; Sanchez, Cristina; Aguilar, Ferran; Nevens, Frederik; Verbeek, Jef; Moreau, Richard; Arroyo, Vicente; Denadai Souza, Alexandre; Claria, Joan; Lambrechts, Diether; Ghesquiere, Bart; Korf, Hannelie; van der Merwe, Schalk
PI3K/mTOR inhibition induces tumour microenvironment remodelling and sensitises pS6high uterine leiomyosarcoma to PD-1 blockade
CLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
2024-05-062
OAAI
De Wispelaere, Wout; Annibali, Daniela; Tuyaerts, Sandra; Messiaen, Julie; Antoranz, Asier; Shankar, Gautam; Dubroja, Nikolina; Herreros-Pomares, Alejandro; Baiden-Amissah, Regina E. M.; Orban, Marie-Pauline; Delfini, Marcello; Berardi, Emanuele; Van Brussel, Thomas; Schepers, Rogier; Philips, Gino; Boeckx, Bram; Baietti, Maria Francesca; Congedo, Luigi; HoWangYin, Kiave Yune; Bayon, Emilie; Van Rompuy, Anne-Sophie; Leucci, Eleonora; Tabruyn, Sebastien P.; Bosisio, Francesca; Mazzone, Massimiliano; Lambrechts, Diether; Amant, Frederic
Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program
NPJ BREAST CANCER
IF7.6
2024-04-244
OAAI
Geukens, Tatjana; De Schepper, Maxim; van den Bogaert, Wouter; Van Baelen, Karen; Maetens, Marion; Pabba, Anirudh; Mahdami, Amena; Leduc, Sophia; Isnaldi, Edoardo; Nguyen, Ha-Linh; Bachir, Imane; Hajipirloo, Maysam; Zels, Gitte; Van Cauwenberge, Josephine; Borremans, Kristien; Vandecaveye, Vincent; Weynand, Birgit; Vermeulen, Peter; Leucci, Eleonora; Baietti, Maria Francesca; Sflomos, George; Battista, Laura; Brisken, Cathrin; Derksen, Patrick W. B.; Koorman, Thijs; Visser, Daan; Scheele, Colinda L. G. J.; Thommen, Daniela S.; Hatse, Sigrid; Fendt, Sarah-Maria; Vanderheyden, Evy; Van Brussel, Thomas; Schepers, Rogier; Boeckx, Bram; Lambrechts, Diether; Marano, Giuseppe; Biganzoli, Elia; Smeets, Ann; Nevelsteen, Ines; Punie, Kevin; Neven, Patrick; Wildiers, Hans; Richard, Francois; Floris, Giuseppe; Desmedt, Christine
Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases

乳腺癌肝转移中组织病理学生长模式的转录组学特征

CLINICAL & EXPERIMENTAL METASTASIS
IF3.2
2024-03-290
OAAI
Leduc, Sophia; Nguyen, Ha-Linh; Richard, Francois; Zels, Gitte; Mahdami, Amena; De Schepper, Maxim; Maetens, Marion; Pabba, Anirudh; Jaekers, Joris; Latacz, Emily; Bohlok, Ali; Vanderheyden, Evy; Van Brussel, Thomas; Boeckx, Bram; Schepers, Rogier; Lambrechts, Diether; Dirix, Luc; Larsimont, Denis; Vankerckhove, Sophie; Lucidi, Valerio; Topal, Baki; Bachir, Imane; Donckier, Vincent; Floris, Giuseppe; Vermeulen, Peter; Desmedt, Christine
Heterogeneity of the hormone receptor-positive breast tumor immune microenvironment according to patient's body mass index

根据患者体重指数的激素受体阳性乳腺肿瘤免疫微环境的异质性

CANCER RESEARCH
IF16.6
2024-03-220
PRE
Ha-Linh Nguyen; Geukens, Tatjana; De Schepper, Maxim; Van Baelen, Karen; Maetens, Marion; Zels, Gitte; Mahdami, Amena; Isnaldi, Edoardo; Hatse, Sigrid; Verbeke, Joke; Matthys, Christophe; Thienpont, Bernard; Vanderheyden, Evy; Van Brussel, Thomas; Schepers, Rogier; Philips, Gino; Boeckx, Bram; Lambrechts, Diether; Floris, Giuseppe; Richard, Francois; Desmedt, Christine
Highly populated phylogenetic reconstruction in patients with hormone receptor positive-HER2 non-amplified metastatic breast cancer
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Richard, Francois; Geukens, Tatjana; De Schepper, Maxim; Mahdami, Amena; Van Baelen, Karen; Maetens, Marion; Zels, Gitte; Nguyen, Ha-Linh; Pabba, Anirudh; Leduc, Sophoa; Isnaldi, Edoardo; Van Cauwenberge, Josephine; Borremans, Kristien; Izci, Hava; Bachir, Imane; Hatse, Sigrid; Vermeulen, Peter; Vanderheyden, Evy; Boeckx, Bram; Lambrechts, Diether; Smeets, Ann; Nevelsteen, Ines; Punie, Kevin; Neven, Patrick; Wildiers, Hans; Van den Bogaert, Wouter; Demeulemeester, Jonas; Biganzoli, Elia; Floris, Giuseppe; Desmedt, Christine
CD4+T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy

CD4 T细胞活化区分对anti-PD-L1 anti-CTLA4疗法的反应与anti-PD-L1单一疗法

IMMUNITY
IF26.3
2024-03-0112
OAAI
Franken, Amelie; Bila, Michel; Mechels, Aurelie; Kint, Sam; Van Dessel, Jeroen; Pomella, Valentina; Vanuytven, Sebastiaan; Philips, Gino; Bricard, Orian; Xiong, Jieyi; Boeckx, Bram; Hatse, Sigrid; Brussel, Thomas Van; Schepers, Rogier; Van Aerde, Cedric; Geurs, Sarah; Vandecaveye, Vincent; Hauben, Esther; Poorten, Vincent Vander; Verbandt, Sara; Vandereyken, Katy; Qian, Junbin; Tejpar, Sabine; Voet, Thierry; Clement, Paul M.; Lambrechts, Diether

研究方向

暂未获取到该数据
D
Diether Lambrechts
H 指数:122论文数:1,318被引数:6.9万
C
Christine Desmedt
H 指数:75论文数:640被引数:4.9万
M
Marion Maetens
H 指数:25论文数:220被引数:3,552
G
Giuseppe Floris
H 指数:47论文数:486被引数:1.3万
T
Thomas Van Brussel
H 指数:33论文数:141被引数:3,399
P
Patrick Neven
H 指数:88论文数:1,186被引数:3.8万
S
Sigrid Hatse
H 指数:43论文数:209被引数:5,929
H
Hans Wildiers
H 指数:84论文数:979被引数:3.3万
F
François Richard
H 指数:41论文数:472被引数:6,459
M
Maxim De Schepper
H 指数:12论文数:118被引数:918