L. Stirling Churchman - Publications, H-index & Citations

L. Stirling Churchman

harvard medical school

37H指数

127论文数

7.6K被引数

收录论文 51

发表时间

A practical guide to studying genome function using single-molecule genomics 使用单分子基因组学进行基因组功能研究的实用指南

Nature Reviews Molecular Cell Biology

IF90.2

2026-09-14

PREAI

Arnaud R. Krebs; Nicolas Altemose; L. Stirling Churchman; William J. Greenleaf; Vijay Ramani; Michael B. Stadler; Andrew B. Stergachis

Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability 突变核糖体蛋白RPS15通过氧化应激和基因组不稳定性驱动B细胞恶性病变

Nature Communications

IF15.7

2026-03-30

OAAI

Catherine Gutierrez; Marwan Kwok; Neil Ruthen; Peyton Waddicor; Christina Curran; Tamara Ouspenskaia; Doris Fu; Brendan Smalec; Samantha Sedor; Binyamin A. Knisbacher; Anat Biran; Adi Nagler; Filip Garbicz; Tomasz Sewastianik; Johany Penailillo; Fabienne Lucas; Shanye Yin; Aviv Liani; Sarah Chen; Gregory Lazarian; Elizabeth Witten; Nathan Dangle; Ella L. Brunsting; Mei Zheng; Emma S. Lin; Madison J. Lee; Blake Wells; Lucas Pomerance; María Hernández-Sánchez; Shuqiang Li; Ziao Lin; Aziz Al’Khafaji; Lili Wang; Sudhir Thakurela; Kenneth J. Livak; Donna Neuberg; Florence Cymbalista; Gad Getz; Aviv Regev; Stirling Churchman; Elisa ten Hacken; Ruben Carrasco; Sichen Shao; Catherine J. Wu

Translational activators align mRNAs at the small mitoribosomal subunit for translation initiation 翻译激活因子将mRNAs定位于小亚基线粒体核糖体上，以进行翻译起始。

Nature Structural & Molecular Biology

IF10.1

2025-12-03

OAAI

Joseph B. Bridgers; Andreas Carlström; Dawafuti Sherpa; Mary T. Couvillion; Urška Rovšnik; Jingjing Gao; Bowen Wan; Sichen Shao; Martin Ott; L. Stirling Churchman

The regulation and function of post-transcriptional RNA splicing 转录后RNA剪接的调控与功能

NATURE REVIEWS GENETICS

IF52

2025-04-11

PREAI

Choquet, Karine; Patop, Ines L.; Churchman, L. Stirling

Genetic regulation of nascent RNA maturation revealed by direct RNA nanopore sequencing 新生的RNA成熟过程中的遗传调控，通过直接RNA纳米孔测序得以揭示

GENOME RESEARCH

IF5.5

2025-02-14

OAAI

Choquet, Karine; Chaumont, Louis-Philippe; Bache, Simon; Baxter-Koenigs, Autum R.; Churchman, L. Stirling

HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy HIF调节多种翻译的内源性逆转录病毒：对癌症免疫治疗的启示

CELL

IF42.5

2025-02-01

OAAI

Jiang, Qinqin; Braun, David A.; Clauser, Karl R.; Ramesh, Vijyendra; Shirole, Nitin H.; Duke-Cohan, Joseph E.; Nabilsi, Nancy; Kramer, Nicholas J.; Forman, Cleo; Lippincott, Isabelle E.; Klaeger, Susan; Phulphagar, Kshiti M.; Chea, Vipheaviny; Kim, Nawoo; Vanasse, Allison P.; Saad, Eddy; Parsons, Teagan; Carr-Reynolds, Melissa; Carulli, Isabel; Pinjusic, Katarina; Jiang, Yijia; Li, Rong; Syamala, Sudeepa; Rachimi, Suzanna; Verzani, Eva K.; Stevens, Jonathan D.; Lane, William J.; Camp, Sabrina Y.; Meli, Kevin; Pappalardi, Melissa B.; Herbert, Zachary T.; Qiu, Xintao; Cejas, Paloma; Long, Henry W.; Shukla, Sachet A.; Allen, Eliezer M. Van; Choueiri, Toni K.; Churchman, L. Stirling; Abelin, Jennifer G.; Gurer, Cagan; Macbeath, Gavin; Childs, Richard W.; Carr, Steven A.; Keskin, Derin B.; Wu, Catherine J.; Kaelin Jr, William G.

Timing is everything: advances in quantifying splicing kinetics

TRENDS IN CELL BIOLOGY

IF18.1

2024-11-01

PREAI

Merens, Hope E.; Choquet, Karine; Baxter-Koenigs, Autum R.; Churchman, L. Stirling

Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome (Aug, 10.1038/s41594-024-01365-9, 2024)

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-09-19

OAAI

Singh, Vivek; Moran, J. Conor; Itoh, Yuzuru; Soto, Iliana C.; Fontanesi, Flavia; Couvillion, Mary; Huynen, Martijn A.; Churchman, L. Stirling; Barrientos, Antoni; Amunts, Alexey

RNA polymerases reshape chromatin architecture and couple transcription on individual fibers

MOLECULAR CELL

IF16.6

2024-09-01

PREAI

Tullius, Thomas W.; Isaac, R. Stefan; Dubocanin, Danilo; Ranchalis, Jane; Churchman, L. Stirling; Stergachis, Andrew B.

Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome 线粒体体依赖lrpprc-slirp翻译的结构基础

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-08-12

OAAI

Singh, Vivek; Moran, J. Conor; Itoh, Yuzuru; Soto, Iliana C.; Fontanesi, Flavia; Couvillion, Mary; Huynen, Martijn A.; Churchman, L. Stirling; Barrientos, Antoni; Amunts, Alexey

Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle

MOLECULAR CELL

IF16.6

2024-07-01

OAAI

Ietswaart, Robert; Smalec, Brendan M.; Xu, Albert; Choquet, Karine; Mcshane, Erik; Jowhar, Ziad Mohamoud; Guegler, Chantal K.; Baxter-Koenigs, Autum R.; West, Emma R.; Fu, Becky Xu Hua; Gilbert, Luke; Floor, Stephen N.; Churchman, L. Stirling

Central dogma rates in human mitochondria

HUMAN MOLECULAR GENETICS

IF3.2

2024-05-23

PREAI

Mcshane, Erik; Churchman, L. Stirling

Post-transcriptional splicing can occur in a slow-moving zone around the gene

ELIFE

IF0

2024-04-05

OAAI

Cote, Allison; O'Farrell, Aoife; Dardani, Ian; Dunagin, Margaret; Cote, Chris; Wan, Yihan; Bayatpour, Sareh; Drexler, Heather L.; Alexander, Katherine A.; Chen, Fei; Wassie, Asmamaw T.; Patel, Rohan; Pham, Kenneth; Boyden, Edward S.; Berger, Shelly; Phillips-Cremins, Jennifer; Churchman, L. Stirling; Raj, Arjun

A kinetic dichotomy between mitochondrial and nuclear gene expression processes 线粒体和核基因表达过程之间的动力学二分法

MOLECULAR CELL

IF16.6

2024-04-01

PREAI

Mcshane, Erik; Couvillion, Mary; Ietswaart, Robert; Prakash, Gyan; Smalec, Brendan M.; Soto, Iliana; Baxter-Koenigs, Autum R.; Choquet, Karine; Churchman, L. Stirling

Single-nucleoid architecture reveals heterogeneous packaging of mitochondrial DNA

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-02-12

OAAI

Isaac, R. Stefan; Tullius, Thomas W.; Hansen, Katja G.; Dubocanin, Danilo; Couvillion, Mary; Stergachis, Andrew B.; Churchman, L. Stirling

Elongation rate of RNA polymerase II affects pausing patterns across 3' UTRs

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-11-01

OAAI

Khitun, Alexandra; Brion, Christian; Moqtaderi, Zarmik; Geisberg, Joseph, V; Churchman, L. Stirling; Struhl, Kevin

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation RNA聚合酶II暂时暂停协调细胞周期进程和红系分化

DEVELOPMENTAL CELL

IF8.7

2023-10-01

OAAI

Martell, Danya J.; Merens, Hope E.; Caulier, Alexis; Fiorini, Claudia; Ulirsch, Jacob C.; Ietswaart, Robert; Choquet, Karine; Graziadei, Giovanna; Brancaleoni, Valentina; Cappellini, Maria Domenica; Scott, Caroline; Roberts, Nigel; Proven, Melanie; Roy, Noemi B. A.; Babbs, Christian; Higgs, Douglas R.; Sankarsn, Vijay G.; Churchman, L. Stirling

Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression

NATURE CELL BIOLOGY

IF19.1

2023-09-28

OAAI

Kramer, Nicholas J.; Prakash, Gyan; Isaac, R. Stefan; Choquet, Karine; Soto, Iliana; Petrova, Boryana; Merens, Hope E.; Kanarek, Naama; Churchman, L. Stirling

Pre-mRNA splicing order is predetermined and maintains splicing fidelity across multi-intronic transcripts

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-07-13

PREAI

Choquet, Karine; Baxter-Koenigs, Autum R.; Dulk, Sarah-Luisa; Smalec, Brendan M.; Rouskin, Silvi; Churchman, L. Stirling

Intronic small nucleolar RNAs regulate host gene splicing through base pairing with their adjacent intronic sequences

GENOME BIOLOGY

IF9.4

2023-07-06

OAAI

Bergeron, Danny; Faucher-Giguere, Laurence; Emmerichs, Ann-Kathrin; Choquet, Karine; Song, Kristina Sungeun; Deschamps-Francoeur, Gabrielle; Fafard-Couture, Etienne; Rivera, Andrea; Couture, Sonia; Churchman, L. Stirling; Heyd, Florian; Elela, Sherif Abou; Scott, Michelle S. S.

研究方向