Lukas P. Feilen - Publications, H-index & Citations

Lukas P. Feilen

university of copenhagen

5H指数

15论文数

55被引数

收录论文 7

发表时间

Integrative structural analysis of human endosomal NHE6 reveals a lipid-associated gate and disordered C-terminus 人类内体NHE6的整合结构分析揭示了一个脂质相关闸门和无序C末端

Nature Communications

IF15.7

2026-08-11

OAAI

Lukas P. Feilen; Lara K. Sach; Emil E. Tranchant; Milena R. Lalic; Jesper F. Havelund; Céline M. Jeria Cerda; Marie Ginsthofer; Jan Ostendorf; Li Ma; Eric M. Morrow; Nils J. Færgeman; Stine F. Pedersen; Birthe B. Kragelund; Henriette E. Autzen

MAASTY: a (dis)ordered copolymer for structural determination of human membrane proteins in native nanodiscs MAASTY: 一种 (dis) 有序共聚物，用于天然纳米盘中人膜蛋白的结构测定

Nature Communications

IF15.7

2025-12-10

OAAI

Ciara F. Pugh; Lukas P. Feilen; Dušan Živković; Kaia F. Præstegaard; Charalampos Sideris; Neil J. Borthwick; Casper de Lichtenberg; Jani R. Bolla; Anton A. A. Autzen; Henriette E. Autzen

Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site

COMMUNICATIONS BIOLOGY

IF5.1

2023-06-24

OAAI

Chen, Shu-Yu; Feilen, Lukas P.; Chavez-Gutierrez, Lucia; Steiner, Harald; Zacharias, Martin

Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-05-01

OAAI

Schmidt, Fabian C.; Fitz, Katja; Feilen, Lukas P.; Okochi, Masayasu; Steiner, Harald; Langosch, Dieter

Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis

ELIFE

IF0

2022-05-17

OAAI

Feilen, Lukas P.; Chen, Shu-Yu; Fukumori, Akio; Feederle, Regina; Zacharias, Martin; Steiner, Harald

Substrate recruitment by γ-secretase

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2020-09-01

PREAI

Fukumori, Akio; Feilen, Lukas P.; Steiner, Harald

Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2017-05-11

OAAI

Feilen, Lukas P.; Haubrich, Kevin; Strecker, Paul; Probst, Sabine; Eggert, Simone; Stier, Gunter; Sinning, Irmgard; Konietzko, Uwe; Kins, Stefan; Simon, Bernd; Wild, Klemens

研究方向