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收藏Screening of candidate analgesics using a patient-derived human iPSC model of nociception identifies putative compounds for therapeutic treatment使用源自患者的疼痛觉模型人诱导多能干细胞（iPSC）筛选候选镇痛剂，以识别用于治疗性治疗的潜在化合物
Thornton, Jack R.; Capurro, Alberto; Harwood, Sally; Henderson, Thomas C.; Unsworth, Adrienne; Gortler, Franziska; Nagaraja-Grellscheid, Sushma; Telezhkin, Vsevolod; Lako, Majlinda; Sernagor, Evelyne; Armstrong, Lyle 分享 收藏 分享 收藏 Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the RetinaDorgau, Birthe; Georgiou, Maria; Chaudhary, Alexander; Moya-Molina, Marina; Collin, Joseph; Queen, Rachel; Hilgen, Gerrit; Davey, Tracey; Hewitt, Philip; Schmitt, Michael; Kustermann, Stefan; Pognan, Francois; Steel, David H.; Sernagor, Evelyne; Armstrong, Lyle; Lako, Majlinda 分享 收藏 分享 收藏 分享 收藏 Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids来自神经视网膜和视网膜色素上皮的去细胞化细胞外基质衍生肽增强人多能干细胞衍生的视网膜类器官的突触标志物和光反应性的表达Dorgau, Birthe; Felemban, Majed; Hilgen, Gerrit; Kiening, Martin; Zerti, Darin; Hunt, Nicola Claire; Doherty, Mary; Whitfield, Phil; Hallam, Dean; White, Kathryn; Ding, Yuchun; Krasnogor, Natalio; Al-Aama, Jumana; Asfour, Hani Z.; Sernagor, Evelyne; Lako, Majlinda 分享 收藏 Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences从人多能干细胞中视网膜类器官分化的系统比较揭示了阶段特异性，细胞系和方法学差异Mellough, Carla B.; Collin, Joseph; Queen, Rachel; Hilgen, Gerrit; Dorgau, Birthe; Zerti, Darin; Felemban, Majed; White, Kathryn; Sernagor, Evelyne; Lako, Majlinda 分享 收藏 分享 收藏 CRX Expression in Pluripotent Stem Cell-Derived Photoreceptors Marks a Transplantable Subpopulation of Early ConesCRX在多能干细胞衍生的光感受器中的表达标志着早期视锥细胞的可移植亚群Collin, Joseph; Zerti, Darin; Queen, Rachel; Santos-Ferreira, Tiago; Bauer, Roman; Coxhead, Jonathan; Hussain, Rafiqul; Steel, David; Mellough, Carla; Ader, Marius; Sernagor, Evelyne; Armstrong, Lyle; Lako, Majlinda 分享 收藏 分享 收藏 Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosaBuskin, Adriana; Zhu, Lili; Chichagova, Valeria; Basu, Basudha; Mozaffari-Jovin, Sina; Dolan, David; Droop, Alastair; Collin, Joseph; Bronstein, Revital; Mehrotra, Sudeep; Farkas, Michael; Hilgen, Gerrit; White, Kathryn; Pan, Kuan-Ting; Treumann, Achim; Hallam, Dean; Bialas, Katarzyna; Chung, Git; Mellough, Carla; Ding, Yuchun; Krasnogor, Natalio; Przyborski, Stefan; Zwolinski, Simon; Al-Aama, Jumana; Alharthi, Sameer; Xu, Yaobo; Wheway, Gabrielle; Szymanska, Katarzyna; McKibbin, Martin; Inglehearn, Chris F.; Elliott, David J.; Lindsay, Susan; Ali, Robin R.; Steel, David H.; Armstrong, Lyle; Sernagor, Evelyne; Urlaub, Henning; Pierce, Eric; Luehrmann, Reinhard; Grellscheid, Sushma-Nagaraja; Johnson, Colin A.; Lako, Majlinda 分享 收藏 分享 收藏 Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent EfficiencyHallam, Dean; Hilgen, Gerrit; Dorgau, Birthe; Zhu, Lili; Yu, Min; Bojic, Sanja; Hewitt, Philip; Schmitt, Michael; Uteng, Marianne; Kustermann, Stefan; Steel, David; Nicholds, Mike; Thomas, Robert; Treumann, Achim; Porter, Andrew; Sernagor, Evelyne; Armstrong, Lyle; Lako, Majlinda 分享 收藏 Unsupervised Spike Sorting for Large-Scale, High-Density Multielectrode Arrays用于大规模，高密度多电极阵列的无监督尖峰排序Hilgen, Gerrit; Sorbaro, Martino; Pirmoradian, Sahar; Muthmann, Jens-Oliver; Kepiro, Ibolya Edit; Ullo, Simona; Ramirez, Cesar Juarez; Encinas, Albert Puente; Maccione, Alessandro; Berdondini, Luca; Murino, Vittorio; Sona, Diego; Zanacchi, Francesca Cella; Sernagor, Evelyne; Hennig, Matthias Helge 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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