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R

Reinhard Lührmann

am fassberg 11

100H指数
354论文数
3.6W被引数
收录论文 135
发表时间
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Unbiased screen of human transcriptome reveals an unexpected role of 3’UTRs in translation initiation无偏筛选人类转录组揭示了3'UTRs在翻译起始中的意外作用
errNature Communications
IF15.7
err2026-08-03
err0
errOAAI
errYun Yang; Xiaojuan Fan; Yanwen Ye; Zhenzhen Zhang; Chuyun Chen; Sebastian E. J. Ludwig; Sirui Zhang; Qianyun Lu; Cindy L. Will; Henning Urlaub; Jing Sun; Reinhard Lührmann; Zefeng Wang
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Structural insights into spliceosome fidelity: DHX35-GPATCH1-mediated rejection of aberrant splicing substrates剪接体精确性的结构洞察：DHX35-GPATCH1介导的对异常剪接底物的排斥
errCELL RESEARCH
IF25.9
err2025-02-28
err1
errOAAI
errLi, Yi; Fischer, Paulina; Wang, Mengjiao; Zhou, Qianxing; Song, Aixia; Yuan, Rui; Meng, Wanyu; Chen, Fei Xavier; Luehrmann, Reinhard; Lau, Benjamin; Hurt, Ed; Cheng, Jingdong
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PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5-splice-site selection causing tissue-specific defects
errNATURE COMMUNICATIONS
IF15.7
err2024-04-11
err1
errOAAI
errAtkinson, Robert; Georgiou, Maria; Yang, Chunbo; Szymanska, Katarzyna; Lahat, Albert; Vasconcelos, Elton J. R.; Ji, Yanlong; Molina, Marina Moya; Collin, Joseph; Queen, Rachel; Dorgau, Birthe; Watson, Avril; Kurzawa-Akanbi, Marzena; Laws, Ross; Saxena, Abhijit; Beh, Chia Shyan; Siachisumo, Chileleko; Goertler, Franziska; Karwatka, Magdalena; Davey, Tracey; Inglehearn, Chris F.; Mckibbin, Martin; Luehrmann, Reinhard; Steel, David H.; Elliott, David J.; Armstrong, Lyle; Urlaub, Henning; Ali, Robin R.; Grellscheid, Sushma-Nagaraja; Johnson, Colin A.; Mozaffari-Jovin, Sina; Lako, Majlinda
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Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins二聚剪接体的cryo-em分析为B复合蛋白的功能提供了新的见解
errEMBO JOURNAL
IF8.3
err2024-02-21
err4
errOAAI
errZhang, Zhenwei; Kumar, Vinay; Dybkov, Olexandr; Will, Cindy L.; Urlaub, Henning; Stark, Holger; Luehrmann, Reinhard
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cDNA cloning and characterization of the human U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err44
errOAAI
errPluk, H; Soffner, J; Lührmann, R; van Venrooij, WJ
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Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err195
errOAAI
errWatkins, NJ; Dickmanns, A; Lührmann, R
err分享
err收藏
The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several US-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err148
errOAAI
errAchsel, T; Ahrens, K; Brahms, H; Teigelkamp, S; Lührmann, R
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Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err38
errOAAI
errWatkins, Nicholas J.; Lemm, Ira; Luehrmann, Reinhard
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U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes纯化的人17s U2 snRNPs和剪接体A和B复合物中的U2 snRNA-蛋白质接触
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err52
errOAAI
errDybkov, O; Will, CL; Deckert, J; Behzadnia, N; Hartmuth, M; Lührmann, R
err分享
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Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err283
errOAAI
errDeckert, Jochen; Hartmuth, Maus; Boehringer, Daniel; Behzadnia, Nastaran; Will, Cindy L.; Kastner, Berthold; Stark, Holger; Urlaub, Henning; Luehrmann, Reinhard
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Human U4/U6 snRNP recycling factor p110:: Mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err43
errOAAI
errMedenbach, J; Schreiner, S; Liu, SB; Lührmann, R; Bindereif, A
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Protein-protein and protein-RNA contacts both contribute to the 15.5K-mediated assembly of the U4/U6 snRNP and the box C/D snoRNPs
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err49
errOAAI
errSchultz, Annemarie; Nottrott, Stephanie; Watkins, Nicholas James; Luehrmann, Reinhard
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err收藏
Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err86
errOAAI
errDellaire, G; Makarov, EM; Cowger, JJM; Longman, D; Sutherland, HGE; Lührmann, R; Torchia, J; Bickmore, WA
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The U11-48K protein contacts the 5′ splice site of U12-type introns and the U11-59K protein
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err48
errOAAI
errTurunen, Janne J.; Will, Cindy L.; Grote, Michael; Luerhrmann, Reinhard; Frilander, Mikko J.
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Role of pre-rRNA base pairing and 80S complex formation in subnucleolar localization of the U3 snoRNP
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err40
errOAAI
errGranneman, S; Vogelzangs, J; Lührmann, R; van Venrooij, WJ; Pruijn, GJM; Watkins, NJ
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Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err84
errOAAI
errSchneider, C; Will, CL; Makarova, OV; Makarov, EM; Lührmann, R
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Conservation of the Protein Composition and Electron Microscopy Structure of Drosophila melanogaster and Human Spliceosomal Complexes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err173
errOAAI
errHerold, Nadine; Will, Cindy L.; Wolf, Elmar; Kastner, Berthold; Urlaub, Henning; Luehrmann, Reinhard
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Molecular Architecture of the Human Prp19/CDC5L Complex
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err121
errOAAI
errGrote, Michael; Wolf, Elmar; Will, Cindy L.; Lemm, Ira; Agafonov, Dmitry E.; Schomburg, Adrian; Fischle, Wolfgang; Urlaub, Henning; Luehrmann, Reinhard
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Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err179
errOAAI
errAgafonov, Dmitry E.; Deckert, Jochen; Wolf, Elmar; Odenwaelder, Peter; Bessonov, Sergey; Will, Cindy L.; Urlaub, Henning; Luehrmann, Reinhard
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Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins
errSCIENCE ADVANCES
IF12.5
err2023-03-03
err9
errOAAI
errDybkov, Olexandr; Preussner, Marco; El Ayoubi, Leyla; Feng, Vivi-Yun; Harnisch, Caroline; Merz, Kilian; Leupold, Paula; Yudichev, Peter; Agafonov, Dmitry E.; Will, Cindy L.; Girard, Cyrille; Dienemann, Christian; Urlaub, Henning; Kastner, Berthold; Heyd, Florian; Luehrmann, Reinhard
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研究方向

暂无研究方向
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