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U

Umber Saleem

university medical center hamburg eppendorf
H指数:15
被引数:1,450

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Higher sensitivity to ouabain-induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes than human adult heart tissue despite similar Na+/K+-ATPase pump current amplitudes

与人类成人心脏组织相比，人类诱导多能干细胞来源的心肌细胞对哇巴因诱导的毒性具有更高的敏感性，尽管两者的Na+/K+-ATP酶泵电流幅度相似。

British Journal of Pharmacology
IF7.7
2026-02-230
OAAI
Djemail Ismaili; Paavo Virtanen; Junsoo Im; Paul Brunnbauer; Umber Saleem; Muhammed Ikbal Sönmez; Carl Schulz; Margaret Nandudu; Joris Winters; Cristina E. Molina; Johannes Petersen; Monika Stoll; Ulrich Schotten; Arne Hansen; Thomas Eschenhagen; Jussi T. Koivumäki; Torsten Christ
Fibroblast growth factor 23 and fibroblast growth factor receptor 4 promote cardiac metabolic remodeling in chronic kidney disease

成纤维细胞生长因子23和成纤维细胞生长因子受体4促进慢性肾脏病中心脏代谢重塑

KIDNEY INTERNATIONAL
IF12.6
2025-02-012
PRE
Fuchs, Michaela A. A.; Burke, Emily J.; Latic, Nejla; Murray, Susan L.; Li, Hanjun; Sparks, Matthew A.; Abraham, Dennis; Zhang, Hengtao; Rosenberg, Paul; Saleem, Umber; Hansen, Arne; Miller, Sara E.; Ferreira, Davis; Haenzelmann, Sonja; Hausmann, Fabian; Huber, Tobias; Erben, Reinhold G.; Fisher-Wellman, Kelsey; Wolf, Myles; Grabner, Alexander
Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation
EMBO MOLECULAR MEDICINE
IF8.3
2021-05-1638
OAAI
Cuello, Friederike; Knaust, Anika E.; Saleem, Umber; Loos, Malte; Raabe, Janice; Mosqueira, Diogo; Laufer, Sandra; Schweizer, Michaela; van Der Kraak, Petra; Flenner, Frederik; Ulmer, Barbel M.; Braren, Ingke; Yin, Xiaoke; Theofilatos, Konstantinos; Ruiz-Orera, Jorge; Patone, Giannino; Klampe, Birgit; Schulze, Thomas; Piasecki, Angelika; Pinto, Yigal; Vink, Aryan; Hubner, Norbert; Harding, Sian; Mayr, Manuel; Denning, Chris; Eschenhagen, Thomas; Hansen, Arne
Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes

使用人类诱导的多能干细胞衍生的心肌细胞对药物诱导的收缩性变化进行盲法，多中心评估

TOXICOLOGICAL SCIENCES
IF4.1
2020-05-1855
OAAI
Saleem, Umber; van Meer, Berend J.; Katili, Puspita A.; Yusof, Nurul A. N. Mohd; Mannhardt, Ingra; Garcia, Ana Krotenberg; Tertoolen, Leon; de Korte, Tessa; Vlaming, Maria L. H.; McGlynn, Karen; Nebel, Jessica; Bahinski, Anthony; Harris, Kate; Rossman, Eric; Xu, Xiaoping; Burton, Francis L.; Smith, Godfrey L.; Clements, Peter; Mummery, Christine L.; Eschenhagen, Thomas; Hansen, Arne; Denning, Chris
Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive?

用人类诱导多能干细胞衍生的心肌细胞解锁个性化生物医学和药物发现: 适合目的还是永远难以捉摸？

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
IF0
2020-01-0629
PREAI
de Korte, Tessa; Katili, Puspita A.; Yusof, Nurul A. N. Mohd; van Meer, Berend J.; Saleem, Umber; Burton, Francis L.; Smith, Godfrey L.; Clements, Peter; Mummery, Christine L.; Eschenhagen, Thomas; Hansen, Arne; Denning, Chris
Differentiation of cardiomyocytes and generation of human engineered heart tissue (vol 12, pg 1177, 2017)
NATURE PROTOCOLS
IF16
2019-08-052
OAAI
Breckwoldt, Kaja; Breniere-Letuffe, David; Mannhardt, Ingra; Schulze, Thomas; Ulmer, Barbel; Werner, Tessa; Benzin, Anika; Klampe, Birgit; Reinsch, Marina C.; Laufer, Sandra; Shibamiya, Aya; Prondzynski, Maksymilian; Mearini, Giulia; Schade, Dennis; Fuchs, Sigrid; Neuber, Christiane; Kramer, Elisabeth; Saleem, Umber; Schulze, Mirja L.; Rodriguez, Marita L.; Eschenhagen, Thomas; Hansen, Arne
MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo
CIRCULATION RESEARCH
IF16.2
2018-02-02249
OAAI
Sala, Luca; van Meer, Berend J.; Tertoolen, Leon G. J.; Bakkers, Jeroen; Bellin, Milena; Davis, Richard P.; Denning, Chris; Dieben, Michel A. E.; Eschenhagen, Thomas; Giacomelli, Elisa; Grandela, Catarina; Hansen, Arne; Holman, Eduard R.; Jongbloed, Monique R. M.; Kamel, Sarah M.; Koopman, Charlotte D.; Lachaud, Quentin; Mannhardt, Ingra; Mol, Mervyn P. H.; Mosqueira, Diogo; Orlova, Valeria V.; Passier, Robert; Ribeiro, Marcelo C.; Saleem, Umber; Smith, Godfrey L.; Burton, Francis L.; Mummery, Christine L.
Differentiation of cardiomyocytes and generation of human engineered heart tissue
NATURE PROTOCOLS
IF16
2017-05-11202
PREAI
Breckwoldt, Kaja; Letuffe-Breniere, David; Mannhardt, Ingra; Schulze, Thomas; Ulmer, Baerbel; Werner, Tessa; Benzin, Anika; Klampe, Birgit; Reinsch, Marina C.; Laufer, Sandra; Shibamiya, Aya; Prondzynski, Maksymilian; Mearini, Giulia; Schade, Dennis; Fuchs, Sigrid; Neuber, Christiane; Kraemer, Elisabeth; Saleem, Umber; Schulze, Mirja L.; Rodriguez, Marita L.; Eschenhagen, Thomas; Hansen, Arne

研究方向

暂未获取到该数据
A
Arne Hansen
H 指数:53论文数:222被引数:1.1万
T
Thomas Eschenhagen
H 指数:95论文数:650被引数:3.1万
I
Ingra Mannhardt
H 指数:23论文数:66被引数:3,244
C
Chris Denning
H 指数:50论文数:193被引数:7,855
T
Thomas G. Schulze
H 指数:96论文数:826被引数:5.9万
B
Bärbel Ulmer
H 指数:18论文数:40被引数:1,910
B
Birgit Klampe
H 指数:11论文数:38被引数:1,086
T
Tessa de Korte
H 指数:10论文数:45被引数:447
P
Peter Clements
H 指数:12论文数:39被引数:708
C
Christine L. Mummery
H 指数:99论文数:661被引数:3.8万