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Impact of bimekizumab and certolizumab pegol on efficacy, safety and osteoblastic activity in radiographic axial spondyloarthritis: results from a phase IIa, multicentre, randomised, double-blind, exploratory study with PET-CT imaging Baraliakos, Xenofon; de Jongh, Jerney; Poddubnyy, Denis; Zwezerijnen, Gerben J. C.; Hemke, Robert; Glatt, Sophie; Shaw, Stevan; Ionescu, Lucian; el Baghdady, Assem; Mann, Joanne; Maguire, Ralph Paul; Vaux, Tom; de Peyrecave, Natasha; Oortgiesen, Marga; Baeten, Dominique; van der Laken, Conny 分享 收藏
Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599) Mercier, Joel; Bani, Massimo; Colson, Anny-Odile; Germani, Massimiliano; Lalla, Marianna; Plisson, Christophe; Huiban, Mickael; Searle, Graham; Mathy, Francois-Xavier; Nicholl, Richard; Otoul, Christian; Smit, Johan Willem; van Asch, Vanja; Wagneur, Michel; Maguire, Ralph Paul 分享 收藏
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Drug characteristics derived from kinetic modeling: combined 11C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A Naganawa, Mika; Gallezot, Jean-Dominique; Finnema, Sjoerd J.; Maguire, Ralph Paul; Mercier, Joel; Nabulsi, Nabeel B.; Kervyn, Sophie; Henry, Shannan; Nicolas, Jean-Marie; Huang, Yiyun; Chen, Ming-Kai; Hannestad, Jonas; Klitgaard, Henrik; Stockis, Armel; Carson, Richard E. 分享 收藏
Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density Cawthorne, Christopher; Maguire, Paul; Mercier, Joel; Sciberras, David; Serdons, Kim; Bormans, Guy; de Hoon, Jan; Van Laere, Koen; Koole, Michel 分享 收藏
A Comparative Study of in vitro Assays for Predicting the Nonspecific Binding of PET Imaging Agents in vivo Gobbi, Luca; Mercier, Joel; Bang-Andersen, Benny; Nicolas, Jean-Marie; Reilly, John; Wagner, Bjoern; Whitehead, David; Briard, Emmanuelle; Maguire, R. Paul; Borroni, Edilio; Auberson, Yves P. 分享 收藏
The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease (vol 9, pg 553, 2019) Stephenson, Diane; Hill, Derek; Cedarbaum, Jesse M.; Tome, Maria; Vamvakas, Spiros; Romero, Klaus; Conrado, Daniela J.; Dexter, David T.; Seibyl, John; Jennings, Danna; Nicholas, Timothy; Matthews, Dawn; Xie, Zhiyong; Imam, Syed; Maguire, Paul; Russell, David; Gordon, Mark Forrest; Stebbins, Glenn T.; Somer, Ed; Gallagher, Jill; Roach, Arthur; Basseches, Peter; Grosset, Donald; Marek, Ken 分享 收藏
Assessment of a white matter reference region for 11C-UCB-J PET quantification Rossano, Samantha; Toyonaga, Takuya; Finnema, Sjoerd J.; Naganawa, Mika; Lu, Yihuan; Nabulsi, Nabeel; Ropchan, Jim; De Bruyn, Steven; Otoul, Christian; Stockis, Armel; Nicolas, Jean-Marie; Martin, Paul; Mercier, Joel; Huang, Yiyun; Maguire, R. Paul; Carson, Richard E. 分享 收藏
The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease Stephenson, Diane; Hill, Derek; Cedarbaum, Jesse M.; Tome, Maria; Vamvakas, Spiros; Romero, Klaus; Conrado, Daniela J.; Dexter, David T.; Seibyl, John; Jennings, Danna; Nicholas, Timothy; Matthews, Dawn; Xie, Zhiyong; Imam, Syed; Maguire, Paul; Russell, David; Gordon, Mark Forrest; Stebbin, Glenn T.; Somer, Ed; Gallagher, Jill; Roach, Arthur; Basseches, Peter; Grosset, Donald; Marek, Kenneth 分享 收藏
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A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers Finnema, Sjoerd J.; Rossano, Samantha; Naganawa, Mika; Henry, Shannan; Gao, Hong; Pracitto, Richard; Maguire, Ralph P.; Mercier, Joel; Kervyn, Sophie; Nicolas, Jean-Marie; Klitgaard, Henrik; DeBruyn, Steven; Otoul, Christian; Martin, Paul; Muglia, Pierandrea; Matuskey, David; Nabulsi, Nabeel B.; Huang, Yiyun; Kaminski, Rafal M.; Hannestad, Jonas; Stockis, Armel; Carson, Richard E. 分享 收藏
Quantifying SV2A density and drug occupancy in the human brain using [11C]UCB-J PET imaging and subcortical white matter as reference tissue Koole, Michel; van Aalst, June; Devrome, Martijn; Mertens, Nathalie; Serdons, Kim; Lacroix, Brigitte; Mercier, Joel; Sciberras, David; Maguire, Paul; Van Laere, Koen 分享 收藏
Task-related fMRI responses to a nicotinic acetylcholine receptor partial agonist in schizophrenia: A randomized trial Barch, Deanna M.; Marder, Stephen R.; Harms, Michael P.; Jarskog, L. Fredrik; Buchanan, Robert W.; Cronenwett, Will; Chen, Li-Shiun; Weiss, Markus; Maguire, Ralph P.; Pezous, Nicole; Feuerbach, Dominik; Lopez-Lopez, Cristina; Johns, Donald R.; Behrje, Rhett B.; Gomez-Mancilla, Baltazar 分享 收藏
Coalition Against Major Diseases/European Medicines Agency biomarker qualification of hippocampal volume for enrichment of clinical trials in predementia stages of Alzheimer's disease Hill, Derek L. G.; Schwarz, Adam J.; Isaac, Maria; Pani, Luca; Vamvakas, Spiros; Hemmings, Robert; Carrillo, Maria C.; Yu, Peng; Sun, Jia; Beckett, Laurel; Boccardi, Marina; Brewer, James; Brumfield, Martha; Cantillon, Marc; Cole, Patricia E.; Fox, Nick; Frisoni, Giovanni B.; Jack, Clifford; Kelleher, Thomas; Luo, Feng; Novak, Gerald; Maguire, Paul; Meibach, Richard; Patterson, Patricia; Bain, Lisa; Sampaio, Cristina; Raunig, David; Soares, Holly; Suhy, Joyce; Wang, Huanli; Wolz, Robin; Stephenson, Diane 分享 收藏
Arterial Transit Time Effects in Pulsed Arterial Spin Labeling CBF Mapping: Insight From a PET and MR Study in Normal Human Subjects Qiu, Maolin; Maguire, R. Paul; Arora, Jagriti; Planeta-Wilson, Beata; Weinzimmer, David; Wang, Jinghua; Wang, Yuenan; Kim, Hyeonjin; Rajeevan, Nallakkandi; Huang, Yiyun; Carson, Richard E.; Constable, R. Todd 分享 收藏
Kinetic modeling of the serotonin 5-HT1B receptor radioligand [11C]P943 in humans Gallezot, Jean-Dominique; Nabulsi, Nabeel; Neumeister, Alexander; Planeta-Wilson, Beata; Williams, Wendol A.; Singhal, Tarun; Kim, Sunhee; Maguire, R. Paul; McCarthy, Timothy; Frost, J. James; Huang, Yiyun; Ding, Yu-Shin; Carson, Richard E. 分享 收藏
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