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Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534 (vol 11, 11066, 2021) Xue, Xiaohua; De Leon-Tabaldo, Aimee; Luna-Roman, Rosa; Castro, Glenda; Albers, Michael; Schoetens, Freddy; DePrimo, Samuel; Devineni, Damayanthi; Wilde, Thomas; Goldberg, Steve; Kinzel, Olaf; Hoffmann, Thomas; Fourie, Anne M.; Thurmond, Robin L. 分享 收藏
Phase 2a, randomized, double-blind, placebo-controlled, multicentre, parallel-group study of an H4R-antagonist (JNJ-39758979) in adults with uncontrolled asthma Kollmeier, A. P.; Greenspan, A.; Xu, X. L.; Silkoff, P. E.; Barnathan, E. S.; Loza, M. J.; Jiang, J.; Zhou, B.; Chen, B.; Thurmond, R. L. 分享 收藏
Histamine H4 receptor antagonism prevents the progression of diabetic nephropathy in male DBA2/J mice Pini, Alessandro; Grange, Cristina; Veglia, Eleonora; Argenziano, Monica; Cavalli, Roberta; Guasti, Daniele; Calosi, Laura; Ghe, Corrado; Solarino, Roberto; Thurmond, Robin L.; Camussi, Giovanni; Chazot, Paul L.; Rosa, Arianna Carolina 分享 收藏
Toreforant, A Histamine H4 Receptor Antagonist, in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: Results of 2 Phase II Studies Thurmond, Robin L.; Greenspan, Andrew; Radziszewski, Waldemar; Xu, Xie L.; Miao, Ye; Chen, Bin; Ge, TingTing; Zhou, Bei; Baker, Daniel G.; Pavlova, Dace; Ritchlin, Christopher T.; Tanaka, Yoshiya; Takeuchi, Tsutomu; Smolen, Josef S. 分享 收藏
Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy Genovese, Mark C.; Hsia, Elizabeth; Belkowski, Stanley M.; Chien, Caly; Masterson, Tara; Thurmond, Robin L.; Manthey, Carl L.; Yan, Xiaoyu (David); Ge, Tingting; Franks, Carol; Greenspan, Andrew 分享 收藏
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Effects of JNJ-40929837, a leukotriene A4 hydrolase inhibitor, in a bronchial allergen challenge model of asthma Barchuk, W.; Lambert, J.; Fuhr, R.; Jiang, J. Z.; Bertelsen, K.; Fourie, A.; Liu, X.; Silkoff, P. E.; Barnathan, E. S.; Thurmond, R. 分享 收藏
The Histamine H4 Receptor Antagonist, JNJ 39758979, Is Effective in Reducing Histamine-Induced Pruritus in a Randomized Clinical Study in Healthy Subjects Kollmeier, Alexa; Francke, Klaus; Chen, Bin; Dunford, Paul J.; Greenspan, Andrew J.; Xia, Yichuan; Xu, Xie L.; Zhou, Bei; Thurmond, Robin L. 分享 收藏
RESULTS FROM A PHASE 2A, RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY OF JNJ-40346527, AN ORAL CSF-1R INHIBITOR, IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS DESPITE DISEASE-MODIFYING ANTIRHEUMATIC DRUG THERAPY Genovese, M. C.; Hsia, E.; Belkowski, S.; Chien, C.; Masterson, T.; Thurmond, R.; Manthey, C.; Yan, D.; Ge, T.; Greenspan, A. 分享 收藏
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The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils Dib, Karim; Perecko, Tomas; Jenei, Veronika; McFarlane, Cheryl; Comer, David; Brown, Vanessa; Katebe, Mwape; Scheithauer, Torsten; Thurmond, Robin L.; Chazot, Paul L.; Ennis, Madeleine 分享 收藏
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The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis Cowden, Jeffery M.; Yu, Fuqu; Banie, Homayon; Farahani, Mandana; Ling, Ping; Nguyen, Steven; Riley, Jason P.; Zhang, Mai; Zhu, Jian; Dunford, Paul J.; Thurmond, Robin L. 分享 收藏
Discovery and SAR of 6-Alkyl-2,4-diaminopyrimidines as Histamine H4 Receptor Antagonists Savall, Brad M.; Chavez, Frank; Tays, Kevin; Dunford, Paul J.; Cowden, Jeffery M.; Hack, Michael D.; Wolin, Ronald L.; Thurmond, Robin L.; Edwards, James P. 分享 收藏
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