未登录 Backtracking NOM1::ETV6 fusion to neonatal pathogenesis of t(7;12) (q36;p13) infant AML Bousquets-Munoz, Pablo; Molina, Oscar; Varela, Ignacio; Alvarez-Eguiluz, Angel; Fernandez-Mateos, Javier; Gomez, Ana; Sanchez, Elena G.; Balbin, Milagros; Ruano, David; Ramirez-Orellana, Manuel; Puente, Xose S.; Menendez, Pablo; Velasco-Hernandez, Talia 分享 收藏
MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells Molina, Ester; Garcia-Gutierrez, Lucia; Junco, Vanessa; Perez-Olivares, Mercedes; de Yebenes, Virginia G.; Blanco, Rosa; Quevedo, Laura; Acosta, Juan C.; Marin, Ana V.; Ulgiati, Daniela; Merino, Ramon; Delgado, M. Dolores; Varela, Ignacio; Regueiro, Jose R.; Moreno de Alboran, Ignacio; Ramiro, Almudena R.; Leon, Javier 分享 收藏
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pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation Boix, Olga; Martinez, Marion; Vidal, Santiago; Gimenez-Alejandre, Marta; Palenzuela, Lluis; Lorenzo-Sanz, Laura; Quevedo, Laura; Moscoso, Olivier; Ruiz-Orera, Jorge; Ximenez-Embun, Pilar; Ciriaco, Nikaoly; Nuciforo, Paolo; Stephan-Otto Attolini, Camille; Alba, M. Mar; Munoz, Javier; Tian, Tian V.; Varela, Ignacio; Vivancos, Ana; Cajal, Santiago Ramon; Munoz, Purificacion; Rivas, Carmen; Abad, Maria 分享 收藏
The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte development Azagra, Alba; Meler, Ainara; de Barrios, Oriol; Tomas-Daza, Laureano; Collazo, Olga; Monterde, Beatriz; Obiols, Mireia; Rovirosa, Llorenc; Vila-Casadesus, Maria; Cabrera-Pasadas, Monica; Gusi-Vives, Mar; Graf, Thomas; Varela, Ignacio; Sardina, Jose Luis; Javierre, Biola M.; Parra, Maribel 分享 收藏
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs (May, 10.1038/s41588-018-0114-z, 2018) Gozdecka, Malgorzata; Meduri, Eshwar; Mazan, Milena; Tzelepis, Konstantinos; Dudek, Monika; Knights, Andrew J.; Pardo, Mercedes; Yu, Lu; Choudhary, Jyoti S.; Metzakopian, Emmanouil; Iyer, Vivek; Yun, Haiyang; Park, Naomi; Varela, Ignacio; Bautista, Ruben; Collord, Grace; Dovey, Oliver; Garyfallos, Dimitrios A.; De Braekeleer, Etienne; Kondo, Saki; Cooper, Jonathan; Gottgens, Berthold; Bullinger, Lars; Northcott, Paul A.; Adams, David; Vassiliou, George S.; Huntly, Brian J. P. 分享 收藏
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PLCγ1/PKCθ Downstream Signaling Controls Cutaneous T-Cell Lymphoma Development and Progression Garcia-Diaz, Nuria; Casar, Berta; Alonso-Alonso, Ruth; Quevedo, Laura; Rodriguez, Marta; Ruso-Julve, Fulgencio; Esteve-Codina, Anna; Gut, Marta; Gru, Alejandro A.; Carmen Gonzalez-Vela, Maria; Gut, Ivo; Luis Rodriguez-Peralto, Jose; Varela, Ignacio; Luis Ortiz-Romero, Pablo; Piris, Miguel A.; Pedro Vaque, Jose 分享 收藏
Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL- rearranged B cell acute lymphoblastic leukemia Tejedor, Juan Ramon; Bueno, Clara; Vinyoles, Meritxell; Petazzi, Paolo; Agraz-Doblas, Antonio; Cobo, Isabel; Torres-Ruiz, Raul; Bayon, Gustavo F.; Perez, Raul F.; Lopez-Tamargo, Sara; Gutierrez-Aguera, Francisco; Santamarina-Ojeda, Pablo; Ramirez-Orellana, Manuel; Bardini, Michela; Cazzaniga, Giovanni; Ballerini, Paola; Schneider, Pauline; Stam, Ronald W.; Varela, Ignacio; Fraga, Mario F.; Fernandez, Agustin F.; Menendez, Pablo 分享 收藏
ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer Moreno, Thaidy; Monterde, Beatriz; Gonzalez-Silva, Laura; Betancor-Fernandez, Isabel; Revilla, Carlos; Agraz-Doblas, Antonio; Freire, Javier; Isidro, Pablo; Quevedo, Laura; Blanco, Rosa; Montes-Moreno, Santiago; Cereceda, Laura; Astudillo, Aurora; Casar, Berta; Crespo, Piero; Morales Torres, Cristina; Scaffidi, Paola; Gomez-Roman, Javier; Salido, Eduardo; Varela, Ignacio 分享 收藏
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HDAC7 is a major contributor in the pathogenesis of infant t(4;11) proB acute lymphoblastic leukemia de Barrios, Oriol; Galaras, Alexandros; Trincado, Juan L.; Azagra, Alba; Collazo, Olga; Meler, Ainara; Agraz-Doblas, Antonio; Bueno, Clara; Ballerini, Paola; Cazzaniga, Giovanni; Stam, Ronald W.; Varela, Ignacio; De Lorenzo, Paola; Valsecchi, Maria Grazia; Hatzis, Pantelis; Menendez, Pablo; Parra, Maribel 分享 收藏
The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells MNT转录因子自动调节其表达并支持MYC相关因子X (MAX) 缺陷细胞的增殖 Lafita-Navarro, M. Carmen; Liano-Pons, Judit; Quintanilla, Andrea; Varela, Ignacio; Blanco, Rosa; Ourique, Fabiana; Bretones, Gabriel; Aresti, Julia; Molina, Ester; Carroll, Patrick; Hurlin, Peter; Romero, Octavio A.; Sanchez-Cespedes, Montse; Eisenman, Robert N.; Delgado, M. Dolores; Leon, Javier 分享 收藏
Analysis pipelines for cancer genome sequencing in mice Lange, Sebastian; Engleitner, Thomas; Mueller, Sebastian; Maresch, Roman; Zwiebel, Maximilian; Gonzalez-Silva, Laura; Schneider, Guenter; Banerjee, Ruby; Yang, Fengtang; Vassiliou, George S.; Friedrich, Mathias J.; Saur, Dieter; Varela, Ignacio; Rad, Roland 分享 收藏
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CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity MLL白血病的CD133-directed CAR T细胞: 靶向，非肿瘤清髓毒性 Bueno, Clara; Velasco-Hernandez, Talia; Gutierrez-Aguera, Francisco; Zanetti, Samanta Romina; Baroni, Matteo L.; Sanchez-Martinez, Diego; Molina, Oscar; Closa, Adria; Agraz-Doblas, Antonio; Marin, Pedro; Eyras, Eduardo; Varela, Ignacio; Menendez, Pablo 分享 收藏
Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusions 通过AF4-MLL和MLL-AF4融合体之间的发育合作，在人类胚胎分化过程中增强了血-内皮的规格 Bueno, Clara; Calero-Nieto, Fernando J.; Wang, Xiaonan; Valdes-Mas, Rafael; Gutierrez-Aguera, Francisco; Roca-Ho, Heleia; Ayllon, Veronica; Real, Pedro J.; Arambilet, David; Espinosa, Lluis; Torres-Ruiz, Raul; Agraz-Doblas, Antonio; Varela, Ignacio; de Boer, Jasper; Bigas, Anna; Gottgens, Bertie; Marschalek, Rolf; Menendez, Pablo 分享 收藏
Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis Agraz-Doblas, Antonio; Bueno, Clara; Bashford-Rogers, Rachael; Roy, Anindita; Schneider, Pauline; Bardini, Michela; Ballerini, Paola; Cazzaniga, Gianni; Moreno, Thaidy; Revilla, Carlos; Gut, Marta; Valsecchi, Maria G.; Roberts, Irene; Pieters, Rob; De Lorenzo, Paola; Varela, Ignacio; Menendez, Pablo; Stam, Ronald W. 分享 收藏
Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis Osorio, Fernando G.; Huber, Axel Rosendahl; Oka, Rurika; Verheul, Mark; Patel, Sachin H.; Hasaart, Karlijn; de la Fonteijne, Lisanne; Varela, Ignacio; Camargo, Fernando D.; van Boxtel, Ruben 分享 收藏
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