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SOUND: A phase II trial evaluating the efficacy of molecular profiling of circulating ± tumor tissue DNA for salvagetherapy matching in patients with advanced and refractory carcinoma Riedl, J. M.; Steinlechner, S. M.; Moik, F.; Heitzer, E.; Jahn, S.; Hasenleithner, S.; Doleschal, B.; Weiss, L.; Seeber, A.; Rumpold, H.; Winder, T.; Greil, R.; Jost, P. J.; Hoefler, G.; Speicher, M.; Gerger, A. 分享 收藏
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway STAT3/LKB1通过调控mTORC1/CREB通路调控转移性前列腺癌 Pencik, Jan; Philippe, Cecile; Schlederer, Michaela; Atas, Emine; Pecoraro, Matteo; Grund-Groeschke, Sandra; Li, Wen (Jess); Tracz, Amanda; Heidegger, Isabel; Lagger, Sabine; Trachtova, Karolina; Oberhuber, Monika; Heitzer, Ellen; Aksoy, Osman; Neubauer, Heidi A.; Wingelhofer, Bettina; Orlova, Anna; Witzeneder, Nadine; Dillinger, Thomas; Redl, Elisa; Greiner, Georg; D'Andrea, David; Ostman, Johnny R.; Tangermann, Simone; Hermanova, Ivana; Schaefer, Georg; Sternberg, Felix; Pohl, Elena E.; Sternberg, Christina; Varady, Adam; Horvath, Jaqueline; Stoiber, Dagmar; Malcolm, Tim I.; Turner, Suzanne D.; Parkes, Eileen E.; Hantusch, Brigitte; Egger, Gerda; Rose-John, Stefan; Poli, Valeria; Jain, Suneil; Armstrong, Chris W. D.; Hoermann, Gregor; Goffin, Vincent; Aberger, Fritz; Moriggl, Richard; Carracedo, Arkaitz; McKinney, Cathal; Kennedy, Richard D.; Klocker, Helmut; Speicher, Michael R.; Tang, Dean G.; Moazzami, Ali A.; Heery, David M.; Hacker, Marcus; Kenner, Lukas 分享 收藏
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Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation Carvalhal, Sara; Bader, Ingrid; Rooimans, Martin A.; Oostra, Anneke B.; Balk, Jesper A.; Feichtinger, Rene G.; Beichler, Christine; Speicher, Michael R.; van Hagen, Johanna M.; Waisfisz, Quinten; van Haelst, Mieke; Bruijn, Martijn; Tavares, Alexandra; Mayr, Johannes A.; Wolthuis, Rob M. F.; Oliveira, Raquel A.; de Lange, Job 分享 收藏
Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiency Verheyen, Sarah; Blatterer, Jasmin; Speicher, Michael R.; Bhavani, Gandham SriLakshmi; Boons, Geert-Jan; Ilse, Mai-Britt; Andrae, Dominik; Spross, Jens; Vaz, Frederic Maxime; Kircher, Susanne G.; Posch-Pertl, Laura; Baumgartner, Daniela; Luebke, Torben; Shah, Hitesh; Al Kaissi, Ali; Girisha, Katta M.; Plecko, Barbara 分享 收藏
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Biallelic truncating variants in ATP9A cause a novel neurodevelopmental disorder involving postnatal microcephaly and failure to thrive Vogt, Guido; Verheyen, Sarah; Schwartzmann, Sarina; Ehmke, Nadja; Potratz, Cornelia; Schwerin-Nagel, Anette; Plecko, Barbara; Holtgrewe, Manuel; Seelow, Dominik; Blatterer, Jasmin; Speicher, Michael R.; Kornak, Uwe; Horn, Denise; Mundlos, Stefan; Fischer-Zirnsak, Bjorn; Boschann, Felix 分享 收藏
Profiling of circulating tumor DNA and tumor tissue for treatment selection in patients with advanced and refractory carcinoma: a prospective, two-stage phase II Individualized Cancer Treatment trial 循环肿瘤DNA和肿瘤组织的分析用于晚期和难治性癌症患者的治疗选择: 一项前瞻性，两阶段的II期个体化癌症治疗试验 Riedl, Jakob M.; Hasenleithner, Samantha O.; Pregartner, Gudrun; Scheipner, Lukas; Posch, Florian; Groller, Karin; Kashofer, Karl; Jahn, Stephan W.; Bauernhofer, Thomas; Pichler, Martin; Stoger, Herbert; Berghold, Andrea; Hoefler, Gerald; Speicher, Michael R.; Heitzer, Ellen; Gerger, Armin 分享 收藏
Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction (vol 14, pg 73, 2011) Sperka, Tobias; Song, Zhangfa; Morita, Yohei; Nalapareddy, Kodandaramireddy; Guachalla, Luis Miguel; Lechel, Andre; Begus-Nahrmann, Yvonne; Burkhalter, Martin D.; Mach, Monika; Schlaudraff, Falk; Liss, Birgit; Ju, Zhenyu; Speicher, Michael R.; Rudolph, K. Lenhard 分享 收藏
On-treatment measurements of circulating tumor DNA during FOLFOX therapy in patients with colorectal cancer Moser, Tina; Waldispuehl-Geigl, Julie; Belic, Jelena; Weber, Sabrina; Zhou, Qing; Hasenleithner, Samantha O.; Graf, Ricarda; Terzic, Jasmin Alia; Posch, Florian; Sill, Heinz; Lax, Sigurd; Kashofer, Karl; Hoefler, Gerald; Schoellnast, Helmut; Heitzer, Ellen; Geigl, Jochen B.; Bauernhofer, Thomas; Speicher, Michael R. 分享 收藏
A higherctDNAfraction decreases survival in regorafenib-treated metastatic colorectal cancer patients. Results from the regorafenib's liquid biopsy translational biomarker phaseIIpilot study Unseld, Matthias; Belic, Jelena; Pierer, Kerstin; Zhou, Qing; Moser, Tina; Bauer, Raimund; Piringer, Gudrun; Gerger, Armin; Siebenhuener, Alexander; Speicher, Michael; Heitzer, Ellen; Prager, Gerald W. 分享 收藏
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Profiling of circulating tumour DNA for treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage phase II individualized cancer treatment trial Gerger, A.; Riedl, J. M.; Perakis, S.; Pregartner, G.; Scheipner, L.; Posch, F.; Groller, K.; Kashofer, K.; Jahn, S. W.; Bauernhofer, T.; Pichler, M.; Stoeger, H.; Berghold, A.; Hoefler, G.; Speicher, M.; Heitzer, E. 分享 收藏
Early circulating tumor DNA dynamics as a real-time predictor of FOLFOX efficacy in advanced colorectal cancer patients Moser, Tina; Waldispuehl-Geigl, Julie; Belic, Jelena; Perakis, Samantha; Weber, Sabrina; Zhou, Qing; Sill, Heinz; Lax, Sigurd; Kashofer, Karl; Hoefler, Gerald; Schoellnast, Helmut; Bauernhofer, Thomas; Heitzer, Ellen; Geigl, Jochen B.; Speicher, Michael R. 分享 收藏
Identification of actionable targets in advanced cancer patients from circulating tumor DNA using clinical decision support platforms Perakis, Samantha O.; Weber, Sabrina; Graf, Ricarda; Zhou, Qing; Riedl, Jakob M.; Dandachi, Nadia; Balic, Marija; Gerger, Armin; Schuuring, Ed; Groen, Harry J.; Geigl, Jochen B.; Speicher, Michael R.; Heitzer, Ellen 分享 收藏
Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity Koch, Claudia; Kuske, Andra; Joosse, Simon A.; Yigit, Goekhan; Sflomos, George; Thaler, Sonja; Smit, Daniel J.; Werner, Stefan; Borgmann, Kerstin; Gaertner, Sebastian; Mossahebi Mohammadi, Parinaz; Battista, Laura; Cayrefourcq, Laure; Altmueller, Janine; Salinas-Riester, Gabriela; Raithatha, Kaamini; Zibat, Arne; Goy, Yvonne; Ott, Leonie; Bartkowiak, Kai; Tan, Tuan Zea; Zhou, Qing; Speicher, Michael R.; Mueller, Volkmar; Gorges, Tobias M.; Juecker, Manfred; Thiery, Jean-Paul; Brisken, Cathrin; Riethdorf, Sabine; Alix-Panabieres, Catherine; Pantel, Klaus 分享 收藏
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Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection (vol 10, 4666, 2019) Ulz, Peter; Perakis, Samantha; Zhou, Qing; Moser, Tina; Belic, Jelena; Lazzeri, Isaac; Woelfler, Albert; Zebisch, Armin; Gerger, Armin; Pristauz, Gunda; Petru, Edgar; White, Brandon; Roberts, Charles E. S.; John, John St.; Schimek, Michael G.; Geigl, Jochen B.; Bauernhofer, Thomas; Sill, Heinz; Bock, Christoph; Heitzer, Ellen; Speicher, Michael R. 分享 收藏
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