Kenneth C. Keiler - Publications, H-index & Citations

Kenneth C. Keiler

University of Texas at Austin

31H指数

88论文数

3.8K被引数

收录论文 35

发表时间

Ribosomal protein bL27 protects translating ribosomes from tmRNA-SmpB 核糖体蛋白bL27保护翻译中的核糖体免受tmRNA-SmpB的影响

Science Advances

IF12.5

2026-08-07

OAAI

Divyasorubini Seerpatham; George Wanes; Chathuri Pathirage; Mynthia Cabrera; Edu Usoro; Kristin S. Koutmou; Christine M. Dunham; Paul C. Whitford; Kenneth C. Keiler

A trans-Translation Inhibitor is Potentiated by Zinc and Kills Mycobacterium tuberculosis and Nontuberculous Mycobacteria 一种跨翻译抑制剂被锌增强，可杀死结核分枝杆菌和非结核分枝杆菌

ACS INFECTIOUS DISEASES

IF3.8

2025-04-09

PREAI

Varshney, A; Jia, ZY; Howe, MD; Keiler, KC; Baughn, AD

Antibiotic that inhibits trans-translation blocks binding of EF-Tu to tmRNA but not to tRNA

MBIO

IF4.7

2023-10-31

OAAI

Marathe, Neeraja; Nguyen, Ha An; Alumasa, John N.; Kuzmishin Nagy, Alexandra B.; Vazquez, Michael; Dunham, Christine M.; Keiler, Kenneth C.

Physiology of trans-translation deficiency in Bacillus subtilis - a comparative proteomics study

PROTEOMICS

IF3.9

2023-07-26

OAAI

Vazquez-Hernandez, Melissa; Leedom, Stephanie L.; Keiler, Kenneth C.; Bandow, Julia Elisabeth

Druggable differences: Targeting mechanistic differences between trans-translation and translation for selective antibiotic action

BIOESSAYS

IF2.7

2022-06-19

OAAI

Srinivas, Pooja; Keiler, Kenneth C.; Dunham, Christine M.

Ribosome collisions: New ways to initiate ribosome rescue

CURRENT BIOLOGY

IF7.5

2022-05-01

OAAI

Leedom, Stephanie L.; Keiler, Kenneth C.

Reproducible and accessible analysis of transposon insertion sequencing in Galaxy for qualitative essentiality analyses

BMC MICROBIOLOGY

IF4.2

2021-06-05

OAAI

Lariviere, Delphine; Wickham, Laura; Keiler, Kenneth; Nekrutenko, Anton

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo

NATURE COMMUNICATIONS

IF15.7

2021-03-19

OAAI

Aron, Zachary D.; Mehrani, Atousa; Hoffer, Eric D.; Connolly, Kristie L.; Srinivas, Pooja; Torhan, Matthew C.; Alumasa, John N.; Cabrera, Mynthia; Hosangadi, Divya; Barbor, Jay S.; Cardinale, Steven C.; Kwasny, Steven M.; Morin, Lucas R.; Butler, Michelle M.; Opperman, Timothy J.; Bowlin, Terry L.; Jerse, Ann; Stagg, Scott M.; Dunham, Christine M.; Keiler, Kenneth C.

Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry

NATURE BIOMEDICAL ENGINEERING

IF26.6

2021-01-04

OAAI

Simonson, Andrew W.; Mongia, Agustey S.; Aronson, Matthew R.; Alumasa, John N.; Chan, Dennis C.; Lawanprasert, Atip; Howe, Michael D.; Bolotsky, Adam; Mal, Tapas K.; George, Christy; Ebrahimi, Aida; Baughn, Anthony D.; Proctor, Elizabeth A.; Keiler, Kenneth C.; Medina, Scott H.

Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2020-12-16

OAAI

Senges, Christoph H. R.; Stepanek, Jennifer J.; Wenzel, Michaela; Raatschen, Nadja; Ay, Uemran; Maertens, Yvonne; Prochnow, Pascal; Hernandez, Melissa Vazquez; Yayci, Abdulkadir; Schubert, Britta; Janzing, Niklas B. M.; Warmuth, Helen L.; Kozik, Martin; Bongard, Jens; Alumasa, John N.; Albada, Bauke; Penkova, Maya; Lukezic, Tadeja; Sorto, Nohemy A.; Lorenz, Nicole; Miller, Reece G.; Zhu, Bingyao; Benda, Martin; Stuelke, Joerg; Schaekermann, Sina; Leichert, Lars, I; Scheinpflug, Kathi; Broetz-Oesterhelt, Heike; Hertweck, Christian; Shaw, Jared T.; Petkovic, Hrvoje; Brunel, Jean M.; Keiler, Kenneth C.; Metzler-Nolte, Nils; Bandow, Julia E.

A Small-Molecule Inhibitor of trans-Translation Synergistically Interacts with Cathelicidin Antimicrobial Peptides To Impair Survival of Staphylococcus aureus

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2019-04-01

OAAI

Huang, Yueyang; Alumasa, John N.; Callaghan, Lauren T.; Baugh, R. Samuel; Rae, Christopher D.; Keiler, Kenneth C.; McGillivray, Shauna M.

Investigating the Structural Mechanism of the Stalled Bacterial Ribosome Bound to a Drug that Targets Trans-Translation

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Mehrani, Atousa; Hoffer, Eric D.; Goralski, Tyler D. P.; Keiler, Kenneth C.; Dunham, Christine M.; Stagg, Scott

A New Mechanism for Ribosome Rescue Can Recruit RF1 or RF2 to Nonstop Ribosomes

MBIO

IF4.7

2018-12-21

OAAI

Goralski, Tyler D. P.; Kirimanjeswara, Girish S.; Keiler, Kenneth C.

Tetrazole-Based trans-Translation Inhibitors Kill Bacillus anthracis Spores To Protect Host Cells

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2017-10-01

OAAI

Alumasa, John N.; Goralski, Tyler D. P.; Keiler, Kenneth C.

Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells

ACS INFECTIOUS DISEASES

IF3.8

2017-08-07

OAAI

Alumasa, John N.; Manzanillo, Paolo S.; Peterson, Nicholas D.; Lundrigan, Tricia; Baughn, Anthony D.; Cox, Jeffery S.; Keiler, Kenneth C.

Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA

SCIENTIFIC REPORTS

IF3.9

2017-07-21

OAAI

Dillon, Nicholas A.; Peterson, Nicholas D.; Feaga, Heather A.; Keiler, Kenneth C.; Baughn, Anthony D.

Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2016-06-01

OAAI

Goralski, Tyler D. P.; Dewan, Kalyan K.; Alumasa, John N.; Avanzato, Victoria; Place, David E.; Markley, Rachel L.; Katkere, Bhuvana; Rabadi, Seham M.; Bakshi, Chandra Shekhar; Keiler, Kenneth C.; Kirimanjeswara, Girish S.

Clicking on trans-translation drug targets

FRONTIERS IN MICROBIOLOGY

IF4.5

2015-05-19

OAAI

Alumasa, John N.; Keiler, Kenneth C.

Mechanisms of ribosome rescue in bacteria

NATURE REVIEWS MICROBIOLOGY

IF103.3

2015-04-13

178

PREAI