未登录
分享
收藏
分享
收藏
分享
收藏
分享
收藏Mediator complex subunit Med19 binds directly GATA transcription factors and is required with Med1 for GATA-driven gene regulationin vivo
Immarigeon, Clement; Bernat-Fabre, Sandra; Guillou, Emmanuelle; Verger, Alexis; Prince, Elodie; Benmedjahed, Mohamed A.; Payet, Adeline; Couralet, Marie; Monte, Didier; Villeret, Vincent; Bourbon, Henri-Marc; Boube, Muriel
分享
收藏
分享
收藏
分享
收藏
分享
收藏
分享
收藏Characterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25
Landrieu, Isabelle; Verger, Alexis; Baert, Jean-Luc; Rucktooa, Prakash; Cantrelle, Francois-Xavier; Dewitte, Frederique; Ferreira, Elisabeth; Lens, Zoe; Villeret, Vincent; Monte, Didier
分享
收藏
分享
收藏Virulence Regulation with Venus Flytrap Domains: Structure and Function of the Periplasmic Moiety of the Sensor-Kinase BvgS
Dupre, Elian; Herrou, Julien; Lensink, Marc F.; Wintjens, Rene; Vagin, Alexey; Lebedev, Andrey; Crosson, Sean; Villeret, Vincent; Locht, Camille; Antoine, Rudy; Jacob-Dubuisson, Francoise
分享
收藏
分享
收藏Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches
Villemagne, Baptiste; Flipo, Marion; Blondiaux, Nicolas; Crauste, Celine; Malaquin, Sandra; Leroux, Florence; Piveteau, Catherine; Villeret, Vincent; Brodin, Priscille; Villoutreix, Bruno O.; Sperandio, Olivier; Soror, Sameh H.; Wohlkoenig, Alexandre; Wintjens, Rene; Deprez, Benoit; Baulard, Alain R.; Willand, Nicolas
分享
收藏
分享
收藏Discovery of Novel N-Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis
Flipo, Marion; Willand, Nicolas; Lecat-Guillet, Nathalie; Hounsou, Candide; Desroses, Matthieu; Leroux, Florence; Lens, Zoe; Villeret, Vincent; Wohlkonig, Alexandre; Wintjens, Rene; Christophe, Thierry; Jeon, Hee Kyoung; Locht, Camille; Brodin, Priscille; Baulard, Alain R.; Deprez, Benoit
分享
收藏Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands
Carette, Xavier; Blondiaux, Nicolas; Willery, Eve; Hoos, Sylviane; Lecat-Guillet, Nathalie; Lens, Zoe; Wohlkoenig, Alexandre; Wintjens, Rene; Soror, Sameh H.; Frenois, Frederic; Dirie, Bertrand; Villeret, Vincent; England, Patrick; Lippens, Guy; Deprez, Benoit; Locht, Camille; Willand, Nicolas; Baulard, Alain R.
分享
收藏Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors
Flipo, Marion; Desroses, Matthieu; Lecat-Guillet, Nathalie; Villemagne, Baptiste; Blondiaux, Nicolas; Leroux, Florence; Piveteau, Catherine; Mathys, Vanessa; Flament, Marie-Pierre; Siepmann, Juergen; Villeret, Vincent; Wohlkonig, Alexandre; Wintjens, Rene; Soror, Sameh H.; Christophe, Thierry; Jeon, Hee Kyoung; Locht, Camille; Brodin, Priscille; Deprez, Benoit; Baulard, Alain R.; Willand, Nicolas
分享
收藏NMR structure of the human Mediator MED25 ACID domain
Bontems, Francois; Verger, Alexis; Dewitte, Frederique; Lens, Zoe; Baert, Jean-Luc; Ferreira, Elisabeth; de Launoit, Yvan; Sizun, Christina; Guittet, Eric; Villeret, Vincent; Monte, Didier
分享
收藏Ethionamide Boosters: Synthesis, Biological Activity, and Structure-Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors
Flipo, Marion; Desroses, Matthieu; Lecat-Guillet, Nathalie; Dirie, Bertrand; Carette, Xavier; Leroux, Florence; Piveteau, Catherine; Demirkaya, Fatma; Lens, Zoe; Rucktooa, Prakash; Villeret, Vincent; Christophe, Thierry; Jeon, Hee Kyoung; Locht, Camille; Brodin, Priscille; Deprez, Benoit; Baulard, Alain R.; Willand, Nicolas
分享
收藏