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P

Pasquale Piccolo

telethon institute of genetics and medicine
H指数:18
被引数:1,566

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p62/SQSTM1-KEAP1 complex prevents clearance of ubiquitinated Z alpha-1 antitrypsin and aggravates liver proteotoxicity

p62/SQSTM1-KEAP1复合物阻碍泛素化Z α-1抗胰蛋白酶的清除并加重肝脏蛋白质毒性

Journal of Biological Chemistry
IF3.9
2026-08-070
OAAI
Nunzia Pastore; Sergio Attanasio; Francesco Annunziata; Claudia D’Agostino; Veronica Maffia; Rita Colonna; Teresa Giuliano; Rosa Ferriero; Iolanda Boffa; Donna Palmer; Philip Ng; Rossella De Cegli; Massimo D’Agostino; Florian Rosenberger; Pavel Strnad; Joseph E. Chambers; Stefan J. Marciniak; Jeffrey Teckman; Pasquale Piccolo; Nicola Brunetti-Pierri
Normal urinary oxalate excretion in 4-hydroxy-2-oxo-glutarate aldolase 1 (HOGA1) deficient mice with AGT expression in peroxisomes and not in mitochondria

4-羟基-2-oxo-戊二酸醛缩酶1（HOGA1）缺陷小鼠中，正常尿草酸盐排泄与过氧化物酶体中存在AGT表达且线粒体中无表达。

biochimica et biophysica acta molecular basis of disease
IF0
2025-06-250
PRE
Iolanda Boffa; Rosa Ferriero; Mariarosaria Cancelliere; Edoardo Nusco; Leonardo Gatticchi; Donna Palmer; Philip Ng; Pasquale Piccolo; Barbara Cellini; Kyle Wood; John Knight; Nicola Brunetti-Pierri
Sestrin2 drives ER-phagy in response to protein misfolding

Sestrin2驱动ER-吞噬响应蛋白质错误折叠

DEVELOPMENTAL CELL
IF8.7
2024-08-013
OA
De Leonibus, Chiara; Maddaluno, Marianna; Ferriero, Rosa; Besio, Roberta; Cinque, Laura; Lim, Pei Jin; Palma, Alessandro; De Cegli, Rossella; Gagliotta, Salvatore; Montefusco, Sandro; Iavazzo, Maria; Rohrbach, Marianne; Giunta, Cecilia; Polishchuk, Elena; Medina, Diego Louis; Di Bernardo, Diego; Forlino, Antonella; Piccolo, Pasquale; Settembre, Carmine
MIB2 variants altering NOTCH signalling result in left ventricle hypertrabeculation/non-compaction and are associated with Menetrier-like gastropathy
HUMAN MOLECULAR GENETICS
IF3.2
2016-12-2311
OAAI
Piccolo, Pasquale; Attanasio, Sergio; Secco, Ilaria; Sangermano, Riccardo; Strisciuglio, Caterina; Limongelli, Giuseppe; Miele, Erasmo; Mutarelli, Margherita; Banfi, Sandro; Nigro, Vincenzo; Pons, Tirso; Valencia, Alfonso; Zentilin, Lorena; Campione, Severo; Nardone, Gerardo; Lynnes, Ty C.; Celestino-Soper, Patricia B. S.; Spoonamore, Katherine G.; D'Armiento, Francesco P.; Giacca, Mauro; Staiano, Annamaria; Vatta, Matteo; Collesi, Chiara; Brunetti-Pierri, Nicola
Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis

Wilson疾病蛋白ATP7B利用溶酶体胞吐作用维持铜稳态

DEVELOPMENTAL CELL
IF8.7
2014-06-01230
OAAI
Polishchuk, Elena V.; Concilli, Mafalda; Iacobacci, Simona; Chesi, Giancarlo; Pastore, Nunzia; Piccolo, Pasquale; Paladino, Simona; Baldantoni, Daniela; van IJzendoorn, Sven C. D.; Chan, Jefferson; Chang, Christopher J.; Amoresano, Angela; Pane, Francesca; Pucci, Piero; Tarallo, Antonietta; Parenti, Giancarlo; Brunetti-Pierri, Nicola; Settembre, Carmine; Ballabio, Andrea; Polishchuk, Roman S.
Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency

自噬调节因子TFEB的基因转移可清除毒性蛋白并纠正 α1-抗胰蛋白酶缺乏症中的肝病

EMBO MOLECULAR MEDICINE
IF8.3
2013-02-04138
OAAI
Pastore, Nunzia; Blomenkamp, Keith; Annunziata, Fabio; Piccolo, Pasquale; Mithbaokar, Pratibha; Sepe, Rosa Maria; Vetrini, Francesco; Palmer, Donna; Ng, Philip; Polishchuk, Elena; Iacobacci, Simona; Polishchuk, Roman; Teckman, Jeffrey; Ballabio, Andrea; Brunetti-Pierri, Nicola

研究方向

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N
Nicola Brunetti‐Pierri
H 指数:59论文数:380被引数:2.4万
R
Rosa Ferriero
H 指数:9论文数:19被引数:1,209
S
Sergio Attanasio
H 指数:9论文数:32被引数:245
N
Nunzia Pastore
H 指数:18论文数:45被引数:4,477
R
Rossella De Cegli
H 指数:25论文数:89被引数:3,749
S
Severo Campione
H 指数:17论文数:75被引数:689
P
Patrizia Annunziata
H 指数:14论文数:44被引数:565
E
Edoardo Nusco
H 指数:26论文数:96被引数:2,450
J
Jeffrey Teckman
H 指数:45论文数:181被引数:6,619
A
Annamaria Carissimo
H 指数:28论文数:112被引数:3,329