未登录 Transcriptome profiling reveals a potential role for antagonism of the calcium-sensing receptor in the prophylaxis of idiopathic pulmonary fibrosis Wolffs, Kasope L.; Pass, Daniel A.; Mansfield, Beth; Bruce, Richard T.; Popov, Petar A.; Corrigan, Christopher J.; Ward, Jeremy P. T.; Kemp, Paul J.; Hope-Gill, Benjamin; Riccardi, Daniela 分享 收藏
Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease Choompoo, Narawadee; Bartley, Oliver J. M.; Precious, Sophie V.; Vinh, Ngoc-nga; Schnell, Christian; Garcia, Ana; Roberton, Victoria H.; Williams, Nigel M.; Kemp, Paul J.; Kelly, Claire M.; Rosser, Anne E. 分享 收藏
Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma Yarova, Polina L.; Huang, Ping; Schepelmann, Martin W.; Bruce, Richard; Ecker, Rupert; Nica, Robert; Telezhkin, Vsevolod; Traini, Daniela; Dos Reis, Larissa Gomes; Kidd, Emma J.; Ford, William R.; Broadley, Kenneth J.; Kariuki, Benson M.; Corrigan, Christopher J.; Ward, Jeremy P. T.; Kemp, Paul J.; Riccardi, Daniela 分享 收藏
Calcium-sensing receptor antagonists, calcilytics, prevent activation of human dendritic and epithelial cells by urban particulate matter Mansfield, Bethan; Ho, Tzer-Ren; Mudway, Ian; Lugg, Sebastian T.; Corrigan, Chris J.; Ward, Jeremy P. T.; Thickett, David; Prytherch, Zoe; Scofield, Simon; Kemp, Paul J.; Lewis, Keir E.; Mur, Luis A.; Hawrylowicz, Catherine; Riccardi, Daniela 分享 收藏
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Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation 通过WNT信号调节在成人发病的亨廷顿氏病iPSC衍生的神经元培养物中纠正异常发育 Smith-Geater, Charlene; Hernandez, Sarah J.; Lim, Ryan G.; Adam, Miriam; Wu, Jie; Stocksdale, Jennifer T.; Wassie, Brook T.; Gold, Maxwell Philip; Wang, Keona Q.; Miramontes, Ricardo; Kopan, Lexi; Orellana, Iliana; Joy, Shona; Kemp, Paul J.; Allen, Nicholas D.; Fraenkel, Ernest; Thompson, Leslie M. 分享 收藏
Calcium-sensing receptor (CaSR) drives lung ECM remodelling and fibrosis in murine asthma models and in ageing mice Bruce, Richard; Huang, Ping; Yarova, Polina; Schepelmann, Martin; Schepelmann, Martin; Wolffs, Kasope; Mansfield, Bethan; Ford, William; Kidd, Emma; Chang, Wenhan; Ecker, Rupert; Nica, Robert; Ying, Sun; Kemp, Paul; Riccardi, Daniela 分享 收藏
Therapeutic effects of topical calcilytic in IgE/Th2 and alarmin-driven surrogates of human asthma Huang, Ping; Mansfield, Bethan; Du, Xiaonan; Huang, Qiong; Wang, Wei; William, Ford; Kidd, Emma; Corrigan, Chris; Ward, Jeremy; Kemp, Paul; Sun, Ying; Riccardi, Daniela 分享 收藏
Calcium-sensing receptor (CaSR) antagonists (calcilytics) prevent urban particulate matter (UPM)-induced dendritic cell activation Mansfield, Bethan; Ho, Tzer-Ren; Mudway, Ian; Corrigan, Christopher; Ward, Jeremy; Kemp, Paul; Lewis, Kier; Mur, Luis; Hawrylowicz, Catherine; Riccardi, Daniela 分享 收藏
CALCIUM-SENSING RECEPTOR AS A THERAPEUTIC TARGET FOR PULMONARY FIBROSIS Wolffs, K.; Mansfield, B.; Bruce, R.; Verckist, L.; De Araujo, R. Paes; Attanoos, R.; Ward, J.; Corrigan, C.; Kemp, P.; Adriaensen, D.; Mur, L.; Hope-Gill, B.; Riccardi, D. 分享 收藏
CALCIUM-SENSING RECEPTOR ANTAGONISTS (CALCILYTICS) AS A NOVEL THERAPEUTIC FOR ALARMIN-DRIVEN INFLAMMATORY LUNG DISEASE Mansfield, B.; Huang, P.; Bruce, R.; Ho, T-R; Du, X.; Huang, Q.; Wang, W.; Lugg, S. T.; Ford, W.; Kidd, E.; Corrigan, C.; Ward, J. P. T.; Hawrylowicz, C.; Thickett, D.; Lewis, K. E.; Mur, L.; Kemp, P. J.; Sun, Y.; Riccardi, D. 分享 收藏
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Development of a new calcilytic for the treatment of inflammatory lung disease Yarova, Polina; Schepelmann, Martin; Ferla, Salvatore; Huang, Ping; Telezhkin, Vsevolod; Kidd, Emma; Ford, William; Broadley, Kenneth; Ward, Jeremy; Corrigan, Christopher; Kemp, Paul; Brancale, Andrea; Riccardi, Daniela 分享 收藏
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Comparable efficacy of calcilytic and corticosteroid in short-term and long-term allergic asthma models in vivo Riccardi, Daniela; Huang, Ping; Yarova, Polina; Schepelmann, Martin; Kidd, Emma J.; Ford, William R.; Broadley, Kenneth J.; Corrigan, Christopher J.; Ward, Jeremy Pt; Kemp, Paul J. 分享 收藏
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Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons Telezhkin, Vsevolod; Schnell, Christian; Yarova, Polina; Yung, Sun; Cope, Emma; Hughes, Alis; Thompson, Belinda A.; Sanders, Philip; Geater, Charlene; Hancock, Jane M.; Joy, Shona; Badder, Luned; Connor-Robson, Natalie; Comella, Andrea; Straccia, Marco; Bombau, Georgina; Brown, Jon T.; Canals, Josep M.; Randall, Andrew D.; Allen, Nicholas D.; Kemp, Paul J. 分享 收藏
The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR Brennan, Sarah C.; Wilkinson, William J.; Tseng, Hsiu-Er; Finney, Brenda; Monk, Bethan; Dibble, Holly; Quilliam, Samantha; Warburton, David; Galietta, Luis J.; Kemp, Paul J.; Riccardi, Daniela 分享 收藏
The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure 血管Ca2感应受体调节血管张力和血压 Schepelmann, M.; Yarova, P. L.; Lopez-Fernandez, I.; Davies, T. S.; Brennan, S. C.; Edwards, P. J.; Aggarwal, A.; Graca, J.; Rietdorf, K.; Matchkov, V.; Fenton, R. A.; Chang, W.; Krssak, M.; Stewart, A.; Broadley, K. J.; Ward, D. T.; Price, S. A.; Edwards, D. H.; Kemp, P. J.; Riccardi, D. 分享 收藏
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