未登录 Fragment-to-Lead Medicinal Chemistry Publications in 2024: A Tenth Annual Perspective (vol 68, pg 24830, 2025) 2024年片段到先导药物化学出版物：第十年度展望（卷 68，第 24830 页，2025年） Twigg, David G.; Arai, Kenta; Arkin, Michelle R.; Erlanson, Daniel A.; de Esch, Iwan J. P.; Farkas, Barbara; Fesik, Stephen W.; Jahnke, Wolfgang; Johnson, Christopher N.; Schroeder, Martin 分享 收藏
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Intervertebral disc human nucleus pulposus cells associated with back pain trigger neurite outgrowth in vitro and pain behaviors in rats Jiang, Wensen; Glaeser, Juliane D.; Kaneda, Giselle; Sheyn, Julia; Wechsler, Jacob T.; Stephan, Stephen; Salehi, Khosrowdad; Chan, Julie L.; Tawackoli, Wafa; Avalos, Pablo; Johnson, Christopher; Castaneda, Chloe; Kanim, Linda E. A.; Tanasansomboon, Teerachat; Burda, Joshua E.; Shelest, Oksana; Yameen, Haneen; Perry, Tiffany G.; Kropf, Michael; Cuellar, Jason M.; Seliktar, Dror; Bae, Hyun W.; Stone, Laura S.; Sheyn, Dmitriy 分享 收藏
Human disease-associated calmodulin mutations alter calcineurin function through multiple mechanisms Williams, Ryan B.; Afsar, Md Nure Alam; Tikunova, Svetlana; Kou, Yongjun; Fang, Xuan; Somarathne, Radha P.; Gyawu, Rita F.; Knotts, Garrett M.; Agee, Taylor A.; Garcia, Sara A.; Losordo, Luke D.; Fitzkee, Nicholas C.; Kekenes-Huskey, Peter M.; Davis, Jonathan P.; Johnson, Christopher N. 分享 收藏
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Risk Factors and Comorbidities Associated with Diabetic Kidney Disease Roy, Satyajeet; Schweiker-Kahn, Olga; Jafry, Behjath; Masel-Miller, Rachel; Raju, Riya Sam; O'Neill, Liam Martin Orta; Correia, Caroline Rose; Trivedi, Aditi; Johnson, Christopher; Pilot, Christian; Saddemi, Jackson; Memon, Aatqa; Chen, Austin; McHugh, Sean Paul; Patel, Sawan; Daroshefski, Nicholas Michael; Nguyen, Tatyana; Wissler, Walter; Sharma, Elena; Hunter, Krystal 分享 收藏
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Fragment-based drug discovery to identify small molecule allosteric inhibitors of SHP2 Day, Philip J.; Berdini, Valerio; Castro, Juan; Chessari, Gianni; Davies, Thomas G.; Day, James E.; Fukaya, Satoshi; Hamlett, Chris; Hearn, Keisha; Hiscock, Steve; Holvey, Rhian; Ito, Satoru; Kodama, Yasuo; Matsuo, Kenichi; Nakatsuru, Yoko; Palmer, Nick; Price, Amanda; Shimamura, Tadashi; St Denis, Jeffrey D.; Wallis, Nicola G.; Williams, Glyn; Johnson, Christopher N. 分享 收藏
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction Trembinski, D. Julia; Bink, Diewertje I.; Theodorou, Kosta; Sommer, Janina; Fischer, Ariane; van Bergen, Anke; Kuo, Chao-Chung; Costa, Ivan G.; Schuermann, Christoph; Leisegang, Matthias S.; Brandes, Ralf P.; Alekseeva, Tijna; Brill, Boris; Wietelmann, Astrid; Johnson, Christopher N.; Spring-Connell, Alexander; Kaulich, Manuel; Werfel, Stanislas; Engelhardt, Stefan; Hirt, Marc N.; Yorgan, Kaja; Eschenhagen, Thomas; Kirchhof, Luisa; Hofmann, Patrick; Jae, Nicolas; Wittig, Ilka; Hamdani, Nazha; Bischof, Corinne; Krishnan, Jaya; Houtkooper, Riekelt H.; Dimmeler, Stefanie; Boon, Reinier A. 分享 收藏
KBTBD13 is an actin-binding protein that modulates muscle kinetics de Winter, Josine M.; Molenaar, Joery P.; Yuen, Michaela; van der Pijl, Robbert; Shen, Shengyi; Conijn, Stefan; van de Locht, Martijn; Willigenburg, Menne; Bogaards, Sylvia J. P.; van Kleef, Esmee S. B.; Lassche, Saskia; Persson, Malin; Rassier, Dilson E.; Sztal, Tamar E.; Ruparelia, Avnika A.; Oorschot, Viola; Ramm, Georg; Hall, Thomas E.; Xiong, Zherui; Johnson, Christopher N.; Li, Frank; Kiss, Balazs; Lozano-Vidal, Noelia; Boon, Reinier A.; Marabita, Manuela; Nogara, Leonardo; Blaauw, Bert; Rodenburg, Richard J.; Kusters, Benno; Doorduin, Jonne; Beggs, Alan H.; Granzier, Henk; Campbell, Ken; Ma, Weikang; Irving, Thomas; Malfatti, Edoardo; Romero, Norma B.; Bryson-Richardson, Robert J.; van Engelen, Baziel G. M.; Voermans, Nicol C.; Ottenheijm, Coen A. C. 分享 收藏
Genetic Mosaicism in Calmodulinopathy Wren, Lisa M.; Jimenez-Jaimez, Juan; Al-Ghamdi, Saleh; Al-Aama, Jumana Y.; Bdeir, Amnah; Al-Hassnan, Zuhair N.; Kuan, Jyn L.; Foo, Roger Y.; Potet, Franck; Johnson, Christopher N.; Aziz, Miriam C.; Carvill, Gemma L.; Kaski, Juan-Pablo; Crotti, Lia; Perin, Francesca; Monserrat, Lorenzo; Burridge, Paul W.; Schwartz, Peter J.; Chazin, Walter J.; Bhuiyan, Zahurul A.; George, Alfred L., Jr. 分享 收藏
The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1.5 and RyR2 function Johnson, Christopher N.; Pattanayek, Rekha; Potet, Franck; Rebbeck, Robyn T.; Blackwell, Daniel J.; Nikolaienko, Roman; Sequeira, Vasco; Le Meur, Remy; Radwanski, Przemyslaw B.; Davis, Jonathan P.; Zima, Aleksey, V; Cornea, Razvan L.; Damo, Steven M.; Gyorke, Sandor; George, Alfred L., Jr.; Knollmann, Bjorn C. 分享 收藏
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Novel calmodulin mutations associated with congenital long QT syndrome affect calcium current in human cardiomyocytes 与先天性长QT综合征相关的新型钙调蛋白突变会影响人类心肌细胞的钙电流 Pipilas, Daniel C.; Johnson, Christopher N.; Webster, Gregory; Schlaepfer, Jurg; Fellmann, Florence; Sekarski, Nicole; Wren, Lisa M.; Ogorodnik, Kateryna V.; Chazin, Daniel M.; Chazin, Walter J.; Crotti, Lia; Bhuiyan, Zahurul A.; George, Alfred L., Jr. 分享 收藏
Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks Gomez-Hurtado, Nieves; Boczek, Nicole J.; Kryshtal, Dmytro O.; Johnson, Christopher N.; Sun, Jennifer; Nitu, Florentin R.; Cornea, Razvan L.; Chazin, Walter J.; Calvert, Melissa L.; Tester, David J.; Ackerman, Michael J.; Knollmann, Bjorn C. 分享 收藏
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MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells Beke, Lijs; Kig, Cenk; Linders, Joannes T. M.; Boens, Shannah; Boeckx, An; van Heerde, Erika; Parade, Marc; De Bondt, An; Van den Wyngaert, Ilse; Bashir, Tarig; Ogata, Souichi; Meerpoel, Lieven; Van Eynde, Aleyde; Johnson, Christopher N.; Beullens, Monique; Brehmer, Dirk; Bollen, Mathieu 分享 收藏
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