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Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain 慢性背痛全基因组多基因风险评分的开发和复制 Tsepilov, Yakov A.; Elgaeva, Elizaveta E.; Nostaeva, Arina V.; Compte, Roger; Kuznetsov, Ivan A.; Karssen, Lennart C.; Freidin, Maxim B.; Suri, Pradeep; Williams, Frances M. K.; Aulchenko, Yurii S. 分享 收藏
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Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions 对遗传独立表型的分析确定了与慢性肌肉骨骼疼痛状况相关的共同遗传因素 Tsepilov, Yakov A.; Freidin, Maxim B.; Shadrina, Alexandra S.; Sharapov, Sodbo Z.; Elgaeva, Elizaveta E.; van Zundert, Jan; Karssen, Lennart C.; Suri, Pradeep; Williams, Frances M. K.; Aulchenko, Yurii S. 分享 收藏
Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts Sharapov, Sodbo Z.; Shadrina, Alexandra S.; Tsepilov, Yakov A.; Elgaeva, Elizaveta E.; Tiys, Evgeny S.; Feoktistova, Sofya G.; Zaytseva, Olga O.; Vuckovic, Frano; Cuadrat, Rafael; Jaeger, Susanne; Wittenbecher, Clemens; Karssen, Lennart C.; Timofeeva, Maria; Tillin, Therese; Trbojevic-Akmacic, Irena; Stambuk, Tamara; Rudman, Najda; Kristic, Jasminka; Simunovic, Jelena; Momcilovic, Ana; Vilaj, Marija; Juric, Julija; Slana, Anita; Gudelj, Ivan; Klaric, Thomas; Puljak, Livia; Skelin, Andrea; Kadic, Antonia Jelicic; Van Zundert, Jan; Chaturvedi, Nishi; Campbell, Harry; Dunlop, Malcolm; Farrington, Susan M.; Doherty, Margaret; Dagostino, Concetta; Gieger, Christian; Allegri, Massimo; Williams, Frances; Schulze, Matthias B.; Lauc, Gordan; Aulchenko, Yurii S. 分享 收藏
Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals 从对509,000个人的研究中洞察背痛的遗传结构及其危险因素 Freidin, Maxim B.; Tsepilov, Yakov A.; Palmer, Melody; Karssen, Lennart C.; Suri, Pradeep; Aulchenko, Yurii S.; Williams, Frances M. K.; Boer, Cindy G.; Yau, Michelle S.; Evans, Daniel S.; Gelemanovic, Andrea; Bartz, Traci M.; Nethander, Maria; Arbeeva, Liubov; Neogi, Tuhina; Campbell, Archie; Mellstrom, Dan; Ohlsson, Claes; Marshall, Lynn M.; Orwoll, Eric; Uitterlinden, Andre; Ratter, Jerome, I; Lauc, Gordan; Psaty, Bruce M.; Karlsson, Magnus K.; Lane, Nancy E.; Jarvik, Gail; Polasek, Ozren; Hochberg, Marc; Jordan, Joanne M.; Van Meurs, Joyce B. J.; Jackson, Rebecca; Nielson, Carrie M.; Mitchell, Braxton D.; Smith, Blair H.; Hayward, Caroline; Smith, Nicholas L. 分享 收藏
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain 欧洲血统的158,000个人的全基因组荟萃分析确定了与慢性背痛相关的三个基因座 Suri, Pradeep; Palmer, Melody R.; Tsepilov, Yakov A.; Freidin, Maxim B.; Boer, Cindy G.; Yau, Michelle S.; Evans, Daniel S.; Gelemanovic, Andrea; Bartz, Traci M.; Nethander, Maria; Arbeeva, Liubov; Karssen, Lennart; Neogi, Tuhina; Campbel, Archie; Mellstrom, Dan; Ohlsson, Claes; Marshall, Lynn M.; Orwoll, Eric; Uitterlinden, Andre; Rotter, Jerome I.; Lauc, Gordan; Psaty, Bruce M.; Karlsson, Magnus K.; Lane, Nancy E.; Jarvik, Gail P.; Polasek, Ozren; Hochberg, Marc; Jordan, Joanne M.; Van Meurs, Joyce B. J.; Jackson, Rebecca; Nielson, Carrie M.; Mitchell, Braxton D.; Smith, Blair H.; Hayward, Caroline; Smith, Nicholas L.; Aulchenko, Yurii S.; Williams, Frances M. K. 分享 收藏
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans 欧洲人2型糖尿病的扩展全基因组关联研究 Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia; Gaulton, Kyle J.; Kaakinen, Marika; Pervjakova, Natalia; Pers, Tune H.; Johnson, Andrew D.; Eicher, John D.; Jackson, Anne U.; Ferreira, Teresa; Lee, Yeji; Ma, Clement; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Van Zuydam, Natalie R.; Mahajan, Anubha; Chen, Han; Almgren, Peter; Voight, Ben F.; Grallert, Harald; Mueller-Nurasyid, Martina; Ried, Janina S.; Rayner, Nigel W.; Robertson, Neil; Karssen, Lennart C.; Van Leeuwen, Elisabeth M.; Willems, Sara M.; Fuchsberger, Christian; Kwan, Phoenix; Teslovich, Tanya M.; Chanda, Pritam; Li, Man; Lu, Yingchang; Dina, Christian; Thuillier, Dorothee; Yengo, Loic; Jiang, Longda; Sparso, Thomas; Kestler, Hans A.; Chheda, Himanshu; Eisele, Lewin; Gustafsson, Stefan; Franberg, Mattias; Strawbridge, Rona J.; Benediktsson, Rafn; Hreidarsson, Astradur B.; Kong, Augustine; Sigurdsson, Gunnar; Kerrison, Nicola D.; Luan, Jian'an; Liang, Liming; Meitinger, Thomas; Roden, Michael; Thorand, Barbara; Esko, Tonu; Mihailov, Evelin; Fox, Caroline; Liu, Ching-Ti; Rybin, Denis; Isomaa, Bo; Lyssenko, Valeriya; Tuomi, Tiinamaija; Couper, David J.; Pankow, James S.; Grarup, Niels; Have, Christian T.; Jorgensen, Marit E.; Jorgensen, Torben; Linneberg, Allan; Cornelis, Marilyn C.; Van Dam, Rob M.; Hunter, David J.; Kraft, Peter; Sun, Qi; Edkins, Sarah; Owen, Katharine R.; Perry, John R. B.; Wood, Andrew R.; Zeggini, Eleftheria; Tajes-Fernandes, Juan; Abecasis, Goncalo R.; Bonnycastle, Lori L.; Chines, Peter S.; Stringham, Heather M.; Koistinen, Heikki A.; Kinnunen, Leena; Sennblad, Bengt; Muehleisen, Thomas W.; Noethen, Markus M.; Pechlivanis, Sonali; Baldassarre, Damiano; Gertow, Karl; Humphries, Steve E.; Tremoli, Elena; Klopp, Norman; Meyer, Julia; Steinbach, Gerald; Wennauer, Roman; Eriksson, Johan G.; Mannisto, Satu; Peltonen, Leena; Tikkanen, Emmi; Charpentier, Guillaume; Eury, Elodie; Lobbens, Stephane; Gigante, Bruna; Leander, Karin; McLeod, Olga; Bottinger, Erwin P.; Gottesman, Omri; Ruderfer, Douglas; Blueher, Matthias; Kovacs, Peter; Tonjes, Anke; Maruthur, Nisa M.; Scapoli, Chiara; Erbel, Raimund; Joeckel, Karl-Heinz; Moebus, Susanne; De Faire, Ulf; Hamsten, Anders; Stumvoll, Michael; Deloukas, Panagiotis; Donnelly, Peter J.; Frayling, Timothy M.; Hattersley, Andrew T.; Ripatti, Samuli; Salomaa, Veikko; Pedersen, Nancy L.; Boehm, Bernhard O.; Bergman, Richard N.; Collins, Francis S.; Mohlke, Karen L.; Tuomilehto, Jaakko; Hansen, Torben; Pedersen, Oluf; Barroso, Ines; Lannfelt, Lars; Ingelsson, Erik; Lind, Lars; Lindgren, Cecilia M.; Cauchi, Stephane; Froguel, Philippe; Loos, Ruth J. F.; Balkau, Beverley; Boeing, Heiner; Franks, Paul W.; Gurrea, Aurelio Barricarte; Palli, Domenico; Van der Schouw, Yvonne T.; Altshuler, David; Groop, Leif C.; Langenberg, Claudia; Wareham, Nicholas J.; Sijbrands, Eric; Van Duijn, Cornelia M.; Florez, Jose C.; Meigs, James B.; Boerwinkle, Eric; Gieger, Christian; Strauch, Konstantin; Metspalu, Andres; Morris, Andrew D.; Palmer, Colin N. A.; Hu, Frank B.; Thorsteinsdottir, Unnur; Stefansson, Kari; Dupuis, Josee; Morris, Andrew P.; Boehnke, Michael; McCarthy, Mark I.; Prokopenko, Inga 分享 收藏
Variants in TTC25 affect autistic trait in patients with autism spectrum disorder and general population Vojinovic, Dina; Brison, Nathalie; Ahmad, Shahzad; Noens, Ilse; Pappa, Irene; Karssen, Lennart C.; Tiemeier, Henning; van Duijn, Cornelia M.; Peeters, Hilde; Amin, Najaf 分享 收藏
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A Genome-Wide Association Study in isolated populations reveals new genes associated to common food likings Pirastu, Nicola; Kooyman, Maarten; Traglia, Michela; Robino, Antonietta; Willems, Sara M.; Pistis, Giorgio; Amin, Najaf; Sala, Cinzia; Karssen, Lennart C.; Van Duijn, Cornelia; Toniolo, Daniela; Gasparini, Paolo 分享 收藏
Population-specific genotype imputations using minimac or IMPUTE2 van Leeuwen, Elisabeth M.; Kanterakis, Alexandros; Deelen, Patrick; Kattenberg, Mathijs V.; Slagboom, P. Eline; de Bakker, Paul I. W.; Wijmenga, Cisca; Swertz, Morris A.; Boomsma, Dorret I.; van Duijn, Cornelia M.; Karssen, Lennart C.; Hottenga, Jouke Jan 分享 收藏
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation Horikoshi, Momoko; Maegi, Reedik; van de Bunt, Martijn; Surakka, Ida; Sarin, Antti-Pekka; Mahajan, Anubha; Marullo, Letizia; Thorleifsson, Gudmar; Haegg, Sara; Hottenga, Jouke-Jan; Ladenvall, Claes; Ried, Janina S.; Winkler, Thomas W.; Willems, Sara M.; Pervjakova, Natalia; Esko, Tonu; Beekman, Marian; Nelson, Christopher P.; Willenborg, Christina; Wiltshire, Steven; Ferreira, Teresa; Fernandez, Juan; Gaulton, Kyle J.; Steinthorsdottir, Valgerdur; Hamsten, Anders; Magnusson, Patrik K. E.; Willemsen, Gonneke; Milaneschi, Yuri; Robertson, Neil R.; Groves, Christopher J.; Bennett, Amanda J.; Lehtimaeki, Terho; Viikari, Jorma S.; Rung, Johan; Lyssenko, Valeriya; Perola, Markus; Heid, Iris M.; Herder, Christian; Grallert, Harald; Mueller-Nurasyid, Martina; Roden, Michael; Hypponen, Elina; Isaacs, Aaron; van Leeuwen, Elisabeth M.; Karssen, Lennart C.; Mihailov, Evelin; Houwing-Duistermaat, Jeanine J.; de Craen, Anton J. M.; Deelen, Joris; Havulinna, Aki S.; Blades, Matthew; Hengstenberg, Christian; Erdmann, Jeanette; Schunkert, Heribert; Kaprio, Jaakko; Tobin, Martin D.; Samani, Nilesh J.; Lind, Lars; Salomaa, Veikko; Lindgren, Cecilia M.; Slagboom, P. Eline; Metspalu, Andres; van Duijn, Cornelia M.; Eriksson, Johan G.; Peters, Annette; Gieger, Christian; Jula, Antti; Groop, Leif; Raitakari, Olli T.; Power, Chris; Penninx, Brenda W. J. H.; de Geus, Eco; Smit, Johannes H.; Boomsma, Dorret I.; Pedersen, Nancy L.; Ingelsson, Erik; Thorsteinsdottir, Unnur; Stefansson, Kari; Ripatti, Samuli; Prokopenko, Inga; McCarthy, Mark I.; Morris, Andrew P. 分享 收藏
Characteristics of de novo structural changes in the human genome Kloosterman, Wigard P.; Francioli, Laurent C.; Hormozdiari, Fereydoun; Marschall, Tobias; Hehir-Kwa, Jayne Y.; Abdellaoui, Abdel; Lameijer, Eric-Wubbo; Moed, Matthijs H.; Koval, Vyacheslav; Renkens, Ivo; van Roosmalen, Markus J.; Arp, Pascal; Karssen, Lennart C.; Coe, Bradley P.; Handsaker, Robert E.; Suchiman, Eka D.; Cuppen, Edwin; Thung, Djie Tjwan; McVey, Mitch; Wendl, Michael C.; Uitterlinden, Andre; van Duijn, Cornelia M.; Swertz, Morris A.; Wijmenga, Cisca; van Ommen, GertJan B.; Slagboom, P. Eline; Boomsma, Dorret I.; Schoenhuth, Alexander; Eichler, Evan E.; de Bakker, Paul I. W.; Ye, Kai; Guryev, Victor 分享 收藏
Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking Pirastu, Nicola; Kooyman, Maarten; Traglia, Michela; Robino, Antonietta; Willems, Sara M.; Pistis, Giorgio; Amin, Najaf; Sala, Cinzia; Karssen, Lennart C.; van Duijn, Cornelia M.; Toniolo, Daniela; Gasparini, Paolo 分享 收藏
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels van Leeuwen, Elisabeth M.; Karssen, Lennart C.; Deelen, Joris; Isaacs, Aaron; Medina-Gomez, Carolina; Mbarek, Hamdi; Kanterakis, Alexandros; Trompet, Stella; Postmus, Iris; Verweij, Niek; van Enckevort, David J.; Huffman, Jennifer E.; White, Charles C.; Feitosa, Mary F.; Bartz, Traci M.; Manichaikul, Ani; Joshi, Peter K.; Peloso, Gina M.; Deelen, Patrick; van Dijk, Freerk; Willemsen, Gonneke; de Geus, Eco J.; Milaneschi, Yuri; Penninx, Brenda W. J. H.; Francioli, Laurent C.; Menelaou, Androniki; Pulit, Sara L.; Rivadeneira, Fernando; Hofman, Albert; Oostra, Ben A.; Franco, Oscar H.; Leach, Irene Mateo; Beekman, Marian; de Craen, Anton J. M.; Uh, Hae-Won; Trochet, Holly; Hocking, Lynne J.; Porteous, David J.; Sattar, Naveed; Packard, Chris J.; Buckley, Brendan M.; Brody, Jennifer A.; Bis, Joshua C.; Rotter, Jerome I.; Mychaleckyj, Josyf C.; Campbell, Harry; Duan, Qing; Lange, Leslie A.; Wilson, James F.; Hayward, Caroline; Polasek, Ozren; Vitart, Veronique; Rudan, Igor; Wright, Alan F.; Rich, Stephen S.; Psaty, Bruce M.; Borecki, Ingrid B.; Kearney, Patricia M.; Stott, David J.; Cupples, L. Adrienne; Jukema, J. Wouter; van der Harst, Pim; Sijbrands, Eric J.; Hottenga, Jouke-Jan; Uitterlinden, Andre G.; Swertz, Morris A.; van Ommen, Gert-Jan B.; de Bakker, Paul I. W.; Slagboom, P. Eline; Boomsma, Dorret I.; Wijmenga, Cisca; van Duijn, Cornelia M. 分享 收藏
Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses Demirkan, Ayse; Henneman, Peter; Verhoeven, Aswin; Dharuri, Harish; Amin, Najaf; van Klinken, Jan Bert; Karssen, Lennart C.; de Vries, Boukje; Meissner, Axel; Goraler, Sibel; van den Maagdenberg, Arn M. J. M.; Deelder, Andre M.; 't Hoen, Peter A. C.; van Duijn, Cornelia M.; van Dijk, Ko Willems 分享 收藏
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium Li, Qing; Wojciechowski, Robert; Simpson, Claire L.; Hysi, Pirro G.; Verhoeven, Virginie J. M.; Ikram, Mohammad Kamran; Hoehn, Rene; Vitart, Veronique; Hewitt, Alex W.; Oexle, Konrad; Makela, Kari-Matti; MacGregor, Stuart; Pirastu, Mario; Fan, Qiao; Cheng, Ching-Yu; St Pourcain, Beat; McMahon, George; Kemp, John P.; Northstone, Kate; Rahi, Jugnoo S.; Cumberland, Phillippa M.; Martin, Nicholas G.; Sanfilippo, Paul G.; Lu, Yi; Wang, Ya Xing; Hayward, Caroline; Polasek, Ozren; Campbell, Harry; Bencic, Goran; Wright, Alan F.; Wedenoja, Juho; Zeller, Tanja; Schillert, Arne; Mirshahi, Alireza; Lackner, Karl; Yip, Shea Ping; Yap, Maurice K. H.; Ried, Janina S.; Gieger, Christian; Murgia, Federico; Wilson, James F.; Fleck, Brian; Yazar, Seyhan; Vingerling, Johannes R.; Hofman, Albert; Uitterlinden, Andre; Rivadeneira, Fernando; Amin, Najaf; Karssen, Lennart; Oostra, Ben A.; Zhou, Xin; Teo, Yik-Ying; Tai, E. Shyong; Vithana, Eranga; Barathi, Veluchamy; Zheng, Yingfeng; Siantar, Rosalynn Grace; Neelam, Kumari; Shin, Youchan; Lam, Janice; Yonova-Doing, Ekaterina; Venturini, Cristina; Hosseini, S. Mohsen; Wong, Hoi-Suen; Lehtimaki, Terho; Kahonen, Mika; Raitakari, Olli; Timpson, Nicholas J.; Evans, David M.; Khor, Chiea-Chuen; Aung, Tin; Young, Terri L.; Mitchell, Paul; Klein, Barbara; van Duijn, Cornelia M.; Meitinger, Thomas; Jonas, Jost B.; Baird, Paul N.; Mackey, David A.; Wong, Tien Yin; Saw, Seang-Mei; Parssinen, Olavi; Stambolian, Dwight; Hammond, Christopher J.; Klaver, Caroline C. W.; Williams, Cathy; Paterson, Andrew D.; Bailey-Wilson, Joan E.; Guggenheim, Jeremy A. 分享 收藏
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process Springelkamp, Henriet; Hoehn, Rene; Mishra, Aniket; Hysi, Pirro G.; Khor, Chiea-Chuen; Loomis, Stephanie J.; Bailey, Jessica N. Cooke; Gibson, Jane; Thorleifsson, Gudmar; Janssen, Sarah F.; Luo, Xiaoyan; Ramdas, Wishal D.; Vithana, Eranga; Nongpiur, Monisha E.; Montgomery, GrantW.; Xu, Liang; Mountain, Jenny E.; Gharahkhani, Puya; Lu, Yi; Amin, Najaf; Karssen, Lennart C.; Sim, Kar-Seng; van Leeuwen, Elisabeth M.; Iglesias, Adriana I.; Verhoeven, Virginie J. M.; Hauser, Michael A.; Loon, Seng-Chee; Despriet, Dominiek D. G.; Nag, Abhishek; Venturini, Cristina; Sanfilippo, Paul G.; Schillert, Arne; Kang, Jae H.; Landers, John; Jonasson, Fridbert; Cree, Angela J.; van Koolwijk, Leonieke M. E.; Rivadeneira, Fernando; Souzeau, Emmanuelle; Jonsson, Vesteinn; Menon, Geeta; Weinreb, Robert N.; de Jong, Paulus T. V. M.; Oostra, Ben A.; Uitterlinden, Andre G.; Hofman, Albert; Ennis, Sarah; Thorsteinsdottir, Unnur; Burdon, Kathryn P.; Spector, Timothy D.; Mirshahi, Alireza; Saw, Seang-Mei; Vingerling, Johannes R.; Teo, Yik-Ying; Haines, Jonathan L.; Wolfs, Roger C. W.; Lemij, Hans G.; Tai, E-Shyong; Jansonius, Nomdo M.; Jonas, Jost B.; Cheng, Ching-Yu; Aung, Tin; Viswanathan, Ananth C.; Klaver, Caroline C. W.; Craig, Jamie E.; Macgregor, Stuart; Mackey, David A.; Lotery, Andrew J.; Stefansson, Kari; Bergen, Arthur A. B.; Young, Terri L.; Wiggs, Janey L.; Pfeiffer, Norbert; Wong, Tien-Yin; Pasquale, Louis R.; Hewitt, Alex W.; van Duijn, Cornelia M.; Hammond, Christopher J. 分享 收藏
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma Hysi, Pirro G.; Cheng, Ching-Yu; Springelkamp, Henriet; Macgregor, Stuart; Bailey, Jessica N. Cooke; Wojciechowski, Robert; Vitart, Veronique; Nag, Abhishek; Hewitt, Alex W.; Hohn, Rene; Venturini, Cristina; Mirshahi, Alireza; Ramdas, Wishal D.; Thorleifsson, Gudmar; Vithana, Eranga; Khor, Chiea-Chuen; Stefansson, Arni B.; Liao, Jiemin; Haines, Jonathan L.; Amin, Najaf; Wang, Ya Xing; Wild, Philipp S.; Ozel, Ayse B.; Li, Jun Z.; Fleck, Brian W.; Zeller, Tanja; Staffieri, Sandra E.; Teo, Yik-Ying; Cuellar-Partida, Gabriel; Luo, Xiaoyan; Allingham, R. Rand; Richards, Julia E.; Senft, Andrea; Karssen, Lennart C.; Zheng, Yingfeng; Bellenguez, Celine; Xu, Liang; Iglesias, Adriana I.; Wilson, James F.; Kang, Jae H.; van Leeuwen, Elisabeth M.; Jonsson, Vesteinn; Thorsteinsdottir, Unnur; Despriet, Dominiek D. G.; Ennis, Sarah; Moroi, Sayoko E.; Martin, Nicholas G.; Jansonius, Nomdo M.; Yazar, Seyhan; Tai, E-Shyong; Amouyel, Philippe; Kirwan, James; van Koolwijk, Leonieke M. E.; Hauser, Michael A.; Jonasson, Fridbert; Leo, Paul; Loomis, Stephanie J.; Fogarty, Rhys; Rivadeneira, Fernando; Kearns, Lisa; Lackner, Karl J.; de Jong, Paulus T. V. M.; Simpson, Claire L.; Pennell, Craig E.; Oostra, Ben A.; Uitterlinden, Andre G.; Saw, Seang-Mei; Lotery, Andrew J.; Bailey-Wilson, Joan E.; Hofman, Albert; Vingerling, Johannes R.; Maubaret, Cecilia; Pfeiffer, Norbert; Wolfs, Roger C. W.; Lemij, Hans G.; Young, Terri L.; Pasquale, Louis R.; Delcourt, Cecile; Spector, Timothy D.; Klaver, Caroline C. W.; Small, Kerrin S.; Burdon, Kathryn P.; Stefansson, Kari; Wong, Tien-Yin; Viswanathan, Ananth; Mackey, David A.; Craig, Jamie E.; Wiggs, Janey L.; van Duijn, Cornelia M.; Hammond, Christopher J.; Aung, Tin 分享 收藏
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