未登录 Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes 精细映射和功能研究强调了类风湿关节炎和1型糖尿病的潜在因果变异 Westra, Harm-Jan; Martinez-Bonet, Marta; Onengut-Gumuscu, Suna; Lee, Annette; Luol, Yang; Teslovich, Nikola; Worthington, Jane; Martin, Javier; Huizinga, Tom; Klareskog, Lars; Rantapaa-Dahlqvist, Solbritt; Chen, Wei-Min; Quinlan, Aaron; Todd, John A.; Eyre, Steve; Nigrovic, Peter A.; Regersen, Peter K. G.; Rich, Stephen S.; Raychaudhuri, Soumya 分享 收藏
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An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis Bossini-Castillo, Lara; Campillo-Davo, Diana; Lopez-Isac, Elena; David Carmona, Francisco; Simeon, Carmen P.; Carreira, Patricia; Luis Callejas-Rubio, Jose; Castellvi, Ivan; Fernandez-Nebro, Antonio; Rodriguez-Rodriguez, Luis; Rubio-Rivas, Manel; Garcia-Hernandez, Francisco J.; Belen Madronero, Ana; Beretta, Lorenzo; Santaniello, Alessandro; Lunardi, Claudio; Airo, Paolo; Hoffmann-Vold, Anna-Maria; Kreuter, Alexander; Riemekasten, Gabriela; Witte, Torsten; Hunzelmann, Nicolas; Vonk, MadeIon C.; Voskuyl, Alexandre E.; de Vries-Bouwstra, J.; Shiels, Paul; Herrick, Ariane; Worthington, Jane; Radstake, Timothy R. D. J.; Martin, Javier 分享 收藏
A MIF PROMOTER POLYMORPHISM IS ASSOCIATED WITH THE SUSCEPTIBILITY TO PULMONARY ARTERIAL HYPERTENSION IN DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS PATIENTS Lopez-Isac, E.; Bossini-Castillo, L.; Campillo-Davo, D.; Carmona, F. D.; Simeon, C. P.; Carreira, P.; Callejas-Rubio, J. L.; Castellvi, I.; Fernandez-Nebro, A.; Rodriguez-Rodriguez, L.; Rubio Rivas, M.; Garcia Hernandez, F. J.; Madronero, A. B.; Beretta, L.; Santaniello, A.; Lunardi, C.; Airo, P.; Hoffmann-Vold, A-M.; Kreuter, A.; Riemekasten, G.; Witte, T.; Hunzelmann, N.; Vonk, M. C.; Voskuyl, A. E.; Bouwstra, J. D. V.; Shiels, P.; Herrick, A.; Worthington, J.; Radstake, T. R. D. J.; Martin, J. 分享 收藏
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Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23 McGovern, Amanda; Schoenfelder, Stefan; Martin, Paul; Massey, Jonathan; Duffus, Kate; Plant, Darren; Yarwood, Annie; Pratt, Arthur G.; Anderson, Amy E.; Isaacs, John D.; Diboll, Julie; Thalayasingam, Nishanthi; Ospelt, Caroline; Barton, Anne; Worthington, Jane; Fraser, Peter; Eyre, Stephen; Orozco, Gisela 分享 收藏
Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway Lopez-Isac, Elena; Campillo-Davo, Diana; Bossini-Castillo, Lara; Guerra, Sandra G.; Assassi, Shervin; Pilar Simeon, Carmen; Carreira, Patricia; Ortego-Centeno, Norberto; Garcia de la Pena, Paloma; Beretta, Lorenzo; Santaniello, Alessandro; Bellocchi, Chiara; Lunardi, Claudio; Moroncini, Gianluca; Gabrielli, Armando; Riemekasten, Gabriela; Witte, Torsten; Hunzelmann, Nicolas; Kreuter, Alexander; Distler, Jorg H. W.; Voskuyl, Alexandre E.; de Vries-Bouwstra, Jeska; Herrick, Ariane; Worthington, Jane; Denton, Christopher P.; Fonseca, Carmen; Radstake, Timothy R. D. J.; Mayes, Maureen D.; Martin, Javier 分享 收藏
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A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases Han, Buhm; Pouget, Jennie G.; Slowikowski, Kamil; Stahl, Eli; Lee, Cue Hyunkyu; Diogo, Dorothee; Hu, Xinli; Park, Yu Rang; Kim, Eunji; Gregersen, Peter K.; Dahlqvist, Solbritt Rantapaa; Worthington, Jane; Martin, Javier; Eyre, Steve; Klareskog, Lars; Huizinga, Tom; Chen, Wei-Min; Onengut-Gumuscu, Suna; Rich, Stephen S.; Wray, Naomi R.; Raychaudhuri, Soumya 分享 收藏
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Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis Plant, Darren; Webster, Amy; Nair, Nisha; Oliver, James; Smith, Samantha L.; Eyre, Steven; Hyrich, Kimme L.; Wilson, Anthony G.; Morgan, Ann W.; Isaacs, John D.; Worthington, Jane; Barton, Anne 分享 收藏
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DIFFERENTIAL METHYLATION AS A BIOMARKER OF RESPONSE TO ETANERCEPT IN PATIENTS WITH RHEUMATOID ARTHRITIS 差异甲基化作为类风湿关节炎患者对依那西普反应的生物标志物 Plant, D.; Webster, A.; Nair, N.; Oliver, J.; Smith, S.; Eyre, S.; Hyrich, K. L.; Wilson, A. G.; Morgan, A. W.; Isaacs, J.; Worthington, J.; Barton, A. 分享 收藏
Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study Yarwood, Annie; Viatte, Sebastien; Okada, Yukinori; Plenge, Robert; Yamamoto, Kazuhiko; Barton, Anne; Symmons, Deborah; Raychaudhuri, Soumya; Klareskog, Lars; Gregersen, Peter; Worthington, Jane; Eyre, Steve 分享 收藏
Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci Martin, Paul; McGovern, Amanda; Orozco, Gisela; Duffus, Kate; Yarwood, Annie; Schoenfelder, Stefan; Cooper, Nicholas J.; Barton, Anne; Wallace, Chris; Fraser, Peter; Worthington, Jane; Eyre, Steve 分享 收藏
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases Lenz, Tobias L.; Deutsch, Aaron J.; Han, Buhm; Hu, Xinli; Okada, Yukinori; Eyre, Stephen; Knapp, Michael; Zhernakova, Alexandra; Huizinga, Tom W. J.; Abecasis, Goncalo; Becker, Jessica; Boeckxstaens, Guy E.; Chen, Wei-Min; Franke, Andre; Gladman, Dafna D.; Gockel, Ines; Gutierrez-Achury, Javier; Martin, Javier; Nair, Rajan P.; Noethen, Markus M.; Onengut-Gumuscu, Suna; Rahman, Proton; Rantapaa-Dahlqvist, Solbritt; Stuart, Philip E.; Tsoi, Lam C.; van Heel, David A.; Worthington, Jane; Wouters, Mira M.; Klareskog, Lars; Elder, James T.; Gregersen, Peter K.; Schumacher, Johannes; Rich, Stephen S.; Wijmenga, Cisca; Sunyaev, Shamil R.; de Bakker, Paul I. W.; Raychaudhuri, Soumya 分享 收藏
Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls (vol 47, pg 839, 2015) Fortune, Mary D.; Guo, Hui; Burren, Oliver; Schofield, Ellen; Walker, Neil M.; Ban, Maria; Sawcer, Stephen J.; Bowes, John; Worthington, Jane; Barton, Anne; Eyre, Steve; Todd, John A.; Wallace, Chris 分享 收藏
Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls Fortune, Mary D.; Guo, Hui; Burren, Oliver; Schofield, Ellen; Walker, Neil M.; Ban, Maria; Sawcer, Stephen J.; Bowes, John; Worthington, Jane; Barton, Anne; Eyre, Steve; Todd, John A.; Wallace, Chris 分享 收藏
ASSOCIATION OF TYK2 WITH SYSTEMIC SCLEROSIS, A NEW LOCUS IN THE IL-12 PATHWAY Bossini-Castillo, L.; Lopez-Isac, E.; Guerra, S.; Assassi, S.; Simeon, C. P.; Carreira, P. E.; Ortego-Centeno, N.; Beretta, L.; Lunardi, C.; Riemekasten, G.; Witte, T.; Hunzelmann, N.; Kreuter, A.; Distler, J. H.; Voskuyl, A. E.; de Vries-Bouwstra, J.; Herrick, A.; Worthington, J.; Denton, C.; Fonseca, C.; Radstake, T.; Mayes, M. D.; Martin, J. 分享 收藏
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