Philip D. Dunne - Publications, H-index & Citations

Philip D. Dunne

patrick g. johnston centre for cancer research

35H指数

521论文数

1.3W被引数

收录论文 89

发表时间

Immune and stromal tumour biology associated with neoadjuvant radiotherapy response in locally advanced rectal cancer 局部晚期直肠癌对新辅助放疗的响应相关的免疫和基质肿瘤生物学

British Journal of Cancer

IF6.8

2026-08-18

OAAI

Lily V. S. Hillson; Ashley K. McCulloch; Ross K. McMahon; Phimmada Hatthakarnkul; Aula Ammar; Timothy S. Maughan; Enric Domingo; Sudhir B. Malla; Raheleh Amirkhah; James H. Park; Joanne Edwards; Philip D. Dunne; Sean M. O’Cathail; Campbell S. Roxburgh

Detection of Fusobacterium nucleatum in Colorectal Adenomas Reveals Associations with Immune Molecular Signatures

International Journal of Molecular Sciences

IF4.9

2026-08-15

OAAI

Sara Samir Foad Al-Badran; Natalie Fisher; Philip D. Dunne; Mark Johnstone; Noori Maka; William M. Rooney; Samantha Campbell; Paul Capewell; Ditte Andersen; Gerard Lynch; Stephen McSorley; Joanne Edwards

Mitochondrial metabolism determines chemotherapy sensitivity in colorectal cancer 线粒体代谢决定结直肠癌的化疗敏感性

Nature Metabolism

IF20.8

2026-07-23

OAAI

Deborah Y. Moss; Connor N. Brown; Andrew M. Shaw; Christopher McCann; Nikita Lewis; Matilda Downs; Rebecca Wurelly; Ciara Cunningham; Aaron Philips; Niamh Doherty; Sarah Gallagher; William J. McDaid; Andrew Roe; Aisling Y. Coughlan; Brenton Cavanagh; Callum Ormsby; Fiammetta Falcone; Rachel McCole; Scott Monteith; Emily Rogan; Sudhir B. Malla; Alexandra J. Emerson; Letitia Mohammed-Smith; Shaun Sharkey; Aoife Leonard; Peter F. Gallagher; Arindam Banerjee; Sandra Van Schaeybroeck; Sufyan Pandor; Brian Quinn; Brett Greer; Christopher Elliott; Sarah Maguire; Aideen E. Ryan; Philip D. Dunne; Mary Mallon; Stephanie Craig; Omar Aftab; Laura C. Greaves; Bryan P. Marzullo; Daniel A. Tennant; Vicky Coyle; Ian G. Mills; Owen Sansom; Tríona Ní Chonghaile; Daniel B. Longley; Simon S. McDade; Melissa J. LaBonte; Emma M. Kerr

Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state 病毒模拟将免疫抑制性结直肠癌景观重定向为促炎性和CMS1样再生状态

Communications Biology

IF5.1

2026-05-26

OAAI

Shania M. Corry; Svetlana Sakhnevych; Noha Ehssan Mohamed; Sudhir B. Malla; Ryan Byrne; Andrew Young; Raheleh Amirkhah; Courtney Bull; Andrea Lees; Keara Redmond; Tamsin R. M. Lannagan; Rachel A. Ridgway; Fiona R. Taggart; Natalie C. Fisher; Tim Maughan; Mark Lawler; Andrew D. Campbell; Simon J. Leedham; Aideen E. Ryan; Daniel B. Longley; Donna M. Small; Owen J. Sansom; Philip D. Dunne

Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation 核磷蛋白支持WNT驱动的过度增殖和肿瘤启动

Nature Genetics

IF29

2025-12-18

OAAI

Georgios Kanellos; Chiara Giacomelli; Alexander Raven; Nikola Vlahov; Hu Jin; Pauline Herviou; Sudhir B. Malla; Nadia Nasreddin; Patricia P. Centeno; Constantinos Alexandrou; Kathryn Gilroy; Rachel L. Baird; Kathryn Pennel; June Munro; Joseph A. Waldron; Holly Hall; Leah Officer-Jones; Sheila Bryson; Douglas Strathdee; Sergio Lilla; Sara Zanivan; Vivienne Morrison; Colin Nixon; Rachel A. Ridgway; Crispin Miller; John R. P. Knight; Andrew D. Campbell; Philip D. Dunne; John Le Quesne; Joanne Edwards; Peter J. Park; Martin Bushell; Owen J. Sansom

MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance MAPK驱动的上皮细胞可塑性驱动结直肠癌治疗抵抗

Nature

IF48.5

2025-11-24

PREAI

Mark White; Megan L. Mills; Laura M. Millett; Kathryn Gilroy; Yourae Hong; Lucas B. Zeiger; Rosalin J. Simpson; Shania M. Corry; Amelia Ligeza; Tamsin R. M. Lannagan; Susanti Susanti; Rachel A. Ridgway; Ayse S. Yazgili; Lucile Grzesiak; Raheleh Amirkhah; Catriona A. Ford; Nikola Vlahov; Hannah Tovell; Leah Officer-Jones; Catherine Ficken; Rachel Pennie; Arafath K. Najumudeen; Alexander Raven; Nadia Nasreddin; Ekansh Chauhan; Andrew S. Papanastasiou; Colin Nixon; Vivienne Morrison; Rene Jackstadt; Janet S. Graham; Crispin J. Miller; Sarah J. Ross; Simon T. Barry; Valeria Pavet; Richard H. Wilson; John Le Quesne; Philip D. Dunne; Sabine Tejpar; Simon Leedham; Andrew D. Campbell; Owen J. Sansom

Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding 上皮细胞中一种新型GREMLIN1内吞途径的鉴定，该途径需要BMP结合

Journal of Biological Chemistry

IF3.9

2025-09-29

OAAI

Zhichun Gao; Yuhan Gao; Louise R. Dutton; Melibea Berzosa Suner; Grace Todd; Gregory R. Gipson; Connor Browne; Emma M. Kerr; Carole Daly; Bianca Plouffe; Philip D. Dunne; Dessislava Malinova; Derek P. Brazil

Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis 低覆盖度全基因组测序对溃疡性结肠炎中低级别异型增生的癌前病变进展风险具有强预测作用

GUT

IF25.8

2025-01-29

PREAI

Al Bakir, Ibrahim; Curtius, Kit; Cresswell, George D.; Grant, Heather E.; Nasreddin, Nadia; Smith, Kane; Nowinski, Salpie; Guo, Qingli; Belnoue-Davis, Hayley L.; Fisher, Jennifer; Clarke, Theo; Kimberley, Christopher; Mossner, Maximilian; Dunne, Philip D.; Loughrey, Maurice B.; Speight, Ally; East, James E.; Wright, Nicholas A.; Rodriguez-Justo, Manuel; Jansen, Marnix; Moorghen, Morgan; Baker, Ann-Marie; Leedham, Simon J.; Hart, Ailsa L.; Graham, Trevor A.

Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis 基于深度学习的结直肠癌肿瘤纯度评估及其对分子分析的影响

JOURNAL OF PATHOLOGY

IF5.2

2024-12-22

OAAI

Schoenpflug, Lydia A.; Chatzipli, Aikaterini; Sirinukunwattana, Korsuk; Richman, Susan; Blake, Andrew; Robineau, James; Mertz, Kirsten D.; Verrill, Clare; Leedham, Simon J.; Hardy, Claire; Whalley, Celina; Redmond, Keara; Dunne, Philip; Walker, Steven; Beggs, Andrew D.; Mcdermott, Ultan; Murray, Graeme, I; Samuel, Leslie M.; Seymour, Matthew; Tomlinson, Ian; Quirke, Philip; S CORT Consortium, Jens; Rittscher, Jens; Maughan, Tim; Domingo, Enric; Koelzer, Viktor H.

Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data

SCIENTIFIC REPORTS

IF3.9

2024-12-04

OAAI

Bull, Courtney; Byrne, Ryan M.; Fisher, Natalie C.; Corry, Shania M.; Amirkhah, Raheleh; Edwards, Jessica; Hillson, Lily V. S.; Lawler, Mark; Ryan, Aideen E.; Lamrock, Felicity; Dunne, Philip D.; Malla, Sudhir B.

Identi fi cation and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune in fi ltrate and TGF P as key predictors

EBIOMEDICINE

IF10.8

2024-08-01

OAAI

Domingo, Enric; Rathee, Sanjay; Blake, Andrew; Samuel, Leslie; Murray, Graeme; Sebag-Montefiore, David; Gollins, Simon; West, Nicholas; Begum, Rubina; Richman, Susan; Quirke, Phil; Redmond, Keara; Chatzipli, Aikaterini; Barberis, Alessandro; Hassanieh, Sylvana; Mahmood, Umair; Youdell, Michael; McDermott, Ultan; Koelzer, Viktor; Leedham, Simon; Tomlinson, Ian; Dunne, Philip; Buffa, Francesca M.; Maughan, Timothy S.

Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids

Stem Cells

IF3.6

2024-07-25

OAAI

Naderi-Meshkin, Hojjat; Setyaningsih, Wiwit A. Wahyu; Yacoub, Andrew; Carney, Garrett; Cornelius, Victoria A.; Nelson, Clare-Ann; Kelaini, Sophia; Donaghy, Clare; Dunne, Philip D.; Amirkhah, Raheleh; Zampetaki, Anna; Zeng, Lingfang; Stitt, Alan W.; Lois, Noemi; Grieve, David J.; Margariti, Andriana

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024)

NATURE GENETICS

IF31.8

2024-06-03

OAAI

Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.

Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy

NPJ PRECISION ONCOLOGY

IF8

2024-04-09

OAAI

Lafarge, Maxime W.; Domingo, Enric; Sirinukunwattana, Korsuk; Wood, Ruby; Samuel, Leslie; Murray, Graeme; Richman, Susan D.; Blake, Andrew; Sebag-Montefiore, David; Gollins, Simon; Klieser, Eckhard; Neureiter, Daniel; Huemer, Florian; Greil, Richard; Dunne, Philip; Quirke, Philip; Weiss, Lukas; Rittscher, Jens; Maughan, Tim; Koelzer, Viktor H.

Poor Diagnostic Reproducibility in the Identification of Nonconventional Dysplasia in Colitis Impacts the Application of Histologic Stratification Tools

MODERN PATHOLOGY

IF5.5

2024-03-01

OAAI

Nasreddin, Nadia; Jansen, Marnix; Loughrey, Maurice B.; Wang, Lai Mun; Koelzer, Viktor H.; Rodriguez-Justo, Manuel; Novelli, Marco; Fisher, Jennifer; Brown, Matthew W.; Al Bakir, Ibrahim; Hart, Ailsa L.; Dunne, Philip; Graham, Trevor A.; Leedham, Simon J.

Molecular pathological classification of colorectal cancer-an update(feb, 10.1007/s00428-024-03746-3, 2024)

VIRCHOWS ARCHIV

IF3.1

2024-02-28

OAAI

Dunne, Philip D.; Arends, Mark J.

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer

NATURE GENETICS

IF31.8

2024-02-13

OAAI

Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.

Molecular pathological classification of colorectal cancer-an update 大肠癌的分子病理分类-最新进展

VIRCHOWS ARCHIV

IF3.1

2024-02-06

OAAI

Dunne, Philip D.; Arends, Mark J.

Pre-emptive TIPS in high-risk acute variceal bleeding. An updated and revised individual patient data meta-analysis

HEPATOLOGY

IF15.8

2023-10-02

PREAI

Nicoara-Farcau, Oana; Han, Guohong; Rudler, Marika; Angrisani, Debora; Monescillo, Alberto; Torres, Ferran; Casanovas, Georgina; Bosch, Jaime; Lv, Yong; Dunne, Philip D. J.; Hayes, Peter C.; Thabut, Dominique; Fan, Daiming; Hernandez-Gea, Virginia; Garcia-Pagan, Juan C.

PLAC8-Mediated Activation of NOX4 Signalling Restores Angiogenic Function of Endothelial Colony-Forming Cells in Experimental Hypoxia

CELLS

IF5.2

2023-09-06

OAAI

Pun, Shun Hay; O'Neill, Karla M.; Edgar, Kevin S.; Gill, Eleanor K.; Moez, Arya; Naderi-Meshkin, Hojjat; Malla, Sudhir B.; Hookham, Michelle B.; Alsaggaf, Mohammed; Madishetti, Vinuthna Vani; Botezatu, Bianca; King, William; Brunssen, Coy; Morawietz, Henning; Dunne, Philip D.; Brazil, Derek P.; Medina, Reinhold J.; Watson, Chris J.; Grieve, David J.

研究方向